Richard Jacobs

Future Tech: Almost Here, Round-the-Corner Future Technology Podcast

Future Technologies Poised to Transform Our Lives For The Better
Future Tech: Almost Here, Round-the-Corner Future Technology Podcast

Description

Future Technologies Poised to Transform Our Lives For The Better are the focus of this podcast. Almost here means these technologies are Now Here, or Just Around The Corner: from Bitcoin to Artifical Intelligence, 3D Printing, Blockchain, Virtual Reality and More.

Categories

Education
Technology

Episodes

Financial Transactions – Frank Holmes, HIVE Blockchain Technologies Ltd. – Blockchain, Bitcoin, and The Changing Financial Landscape

Mar 22, 2019 21:43

Description:

Frank Holmes, Interim Executive Chairman of HIVE Blockchain Technologies Ltd.’s board of directors, provides an analysis of blockchain, bitcoin, and the future of finance. Holmes is a seasoned investor and financial strategist. Throughout his illustrious career, he has helmed many financial entities, and is currently the chief executive and chief investment officer at U.S. Global Investors, a forward-thinking mutual fund and asset management firm. 


Holmes talks about his background in finance. As a young analyst, he transitioned into corporate finance and pushed forward until he took his first company public. He became well known in the gold funds market and eventually discovered bitcoin and that was the beginning of his passion for the new currency. His excitement over the processing of these transactions led him to launch a company in the space.


Holmes’ passion for emerging financial markets is perfectly matched to his current role directing the board of directors at HIVE Blockchain Technologies Ltd., and he is leading the company forward evidenced by their significant innovation in the market. HIVE is a growth-oriented, TSX.V-listed company that has built a bridge from the blockchain sector to traditional capital markets. HIVE’s team seeks to create significant long-term shareholder value. HIVE has formed a solid partnership with Genesis Mining Ltd. to create the next wave of blockchain infrastructure. 


HIVE even owns the actual GPU-based digital currency mining facilities in Iceland and Sweden that produce these new digital currencies like Ethereum. Holmes discusses HIVE’s place in the market as a proxy, and he explains the interconnectedness of HIVE to the market, in terms of flow. He discusses the enthusiasm globally for blockchain, and he outlines the arrival of the JP Morgan coin that is backed by US dollars. Holmes goes on to explain regulations and speculation as they relate to investor interests. And he talks about the benefits of cash trades in the market and the future of emerging financial markets. Holmes discusses the mobile gaming industry and the astronomical revenue that is pushing that industry. Wrapping up, Holmes discusses volatility in the markets and how to steer in the right direction to financial stability as technology changes everything in our world.


Holmes is a regular keynote speaker at various international investment conferences and his popular “Frank Talk” CEO blog is one of the most read in the financial industry.

Gamifying Stroke Rehabilitation for Better Outcomes—Dr. John W. Krakauer—Johns Hopkins University School of Medicine, Department of Neurology

Mar 22, 2019 23:19

Description:

Human beings enjoy a level of dexterity superior to most other species by virtue of what’s called the corticospinal tract, which is a projection that reaches from the motor cortex in the brain, down to the brain stem and spinal cord,  and connects directly to the muscles. As beneficial as this special pathway in humans can be, it comes at a cost: even a small amount of damage can have devastating results. When someone suffers from a stroke, it is this pathway that gets damaged and leads to many possible symptoms, including weakness, loss of dexterity, clumsiness, and the inability to isolate joint movements. The key to the best recovery from stroke is very early, very intense rehab, but it can be challenging to motivate people into maintaining such intense work.

Dr. John W. Krakauer works in the Brain, Learning, Animation, and Movement (BLAM) Lab at Johns Hopkins University School of Medicine, where he’s not only studying the differences between movement in health and movement in disease, but also exploring and testing ways of engaging post-stroke patients in the intense rehab routines necessary in order to help them regain as much movement and control over their bodies as possible. He explains how important it is to create emotionally gratifying and motivating experiences for people early on in their recovery in order to engage them in ways that will best amplify the abilities they do have—the abilities they did not lose as a result of stroke. The same idea applies to all types of neurological diseases and injuries, including traumatic brain injury, Parkinson’s disease, cerebellar ataxia, and multiple sclerosis.

At the BLAM lab, they are developing interactive, exciting, and engaging games specifically geared toward patients with neurodegenerative issues, encouraging them to perform miles’ worth of movement without even noticing it. They are also working on forming cohorts of people who have suffered from stroke and who could benefit from working together in multi-player games. The idea is that this would build a sense of competition, thereby making it easier for people to sustain the level of rehabilitative intensity needed. Furthermore, by isolating problems with particular  body parts to particular characters in games, each individual’s specific problem area could be addressed in the most effective way possible. Interested in learning more? Tune in for all the details and visit www.blam-lab.org.



The Smartest Motorcycle Helmet in the World—Jeremy Lu—Jarvish

Mar 21, 2019 23:36

Description:

If you’ve ever ridden a motorcycle, you might understand all too well the drawbacks of the helmet—it makes it hard to see, hard to hear, and feels very insulating. The team at Jarvish set out to improve this while keeping safety as their top priority. They’ve used traditional motorcycle helmets as their starting point, adding a high-resolution front camera for greater visibility in foggy or rainy weather, a sensor and alert system for detecting accidents and contacting an ambulance and next of kin, biosensors to detect the rider’s heart rate and other vitals which may indicate an impending medical emergency, and a crystal-clear sound system. The team at Jarvish has trained their AI to analyze videos and identify objects or vehicles obscured from the rider’s line of sight, as well as remove raindrops from videos and penetrate foggy conditions. All of this data is then analyzed and sent back to the rider warning them of dangers on the road ahead. It’s the world’s first truly smart motorcycle helmet, and it has the ability to save lives.


Jeremy Lu is the CEO of Jarvish and he joins the podcast to discuss all the details of this technology, how they are allowing for comfort customization of their helmets, what’s in store for them over the next year, and how their technology could be implemented in all types of helmets—bicycle, industrial, police, military, and even space helmets.


Previous press kit with most of the content, and below is the most updated crowdfunding prices and new updates: 


- a NASA iTech Finalist (2019) 

- Partnering with Qualcomm for its X-AR helmet.

- JARVISH Tron Electric Helmet: 

The brand just launched an awesome helmet design for the X and X-AR range. The JARVISH Tron Electric Helmet with LED strips, will certainly make riders stand out on the road. Current backers have the option to upgrade their pledges to this design. The LED light could be controlled by voice command or app. 

- secured over $420K in funding on Kickstarter and have continued their funding on Indiegogo.


-Discounted prices on Indiegogo campaign:

 

JARVISH X - USD 499 

JARVISH X-AR - USD 1099

JARVISH Tron X USD 599

JARVISH Tron X-AR USD 1199


The X-AR and X models have been designed with a range of technology integrations, such as voice control, noise cancellation, built-in memory to give riders a safer, more enjoyable on-road experience. The X-AR also includes an AR-powered head-up display (HUD) for riders who prefer visual instructions. 


Press play for more information, reach out with questions via jeremy@jarvish.com, and visit <a href="http://www.jarvish.com">www.jarvish.com</a>. 

The World’s First Electronic Completions Recorder for the Fracking Industry—Brett Chell—Cold Bore Technology

Mar 20, 2019 26:41

Description:

“If you don’t track it you can’t improve it… and you can’t pay enough people to go through the data fast enough to get a handle on it…but every other industry in the world…has switched over to sensors that drive software…which produces ten times the results you could ever get out of humans in the blink of an eye,” says Brett Chell, founder of Cold Bore Technology. 


The company began as a manufacturer of drilling tools, and it was through that line of work that the team at Cold Bore Technology made a realization which would completely change the focus of their efforts: frack locations were missing the operating systems and IOT software that drilling locations—and really every industry in the world—rely upon for efficient, accurate data collection and operations.


Instead, they’ve been relying upon the manual collection of data with the use of notebooks and Excel sheets—an inefficient method with tons of room for errors which could end up costing hundreds of thousands of dollars.


Fracking operations are complex and involve several service companies acting independently but simultaneously; this creates a constant flow of important data which must be accurately captured and organized in order for mistakes and inefficiencies to be identified and corrected.


Cold Bore Technology is offering a solution that will allow for exactly this. Despite being just a small to mid-sized company, they are now working with some of the largest oil companies in the world, delivering a sensor-based software solution and level of automation never before seen in the field.


The results? Greater operational visibility, the ability to identify important and costly errors that would otherwise continue to happen, less expensive and more efficient operations, and the ability to move data through businesses seamlessly and without anyone touching it.


Learn more by visiting coldboretechnology.com

Alexa-Integrated Smart Pillow Designed to Improve Your Sleep—Kevin Houston—REM-Fit

Mar 20, 2019 19:37

Description:

Kevin Houston is head of execution at REM-Fit, a company that was founded about five years ago with the goal of harnessing the power of technology to improve one of the most important aspects of life: sleep. At REM-Fit, sleep is considered the most important factor in recovery, whether you’re recovering from a stressful day at work or an intense workout. The team at REM-Fit is passionate about sleep, and for the past several years they’ve poured that passion into the design, development, and continual improvement of a product which actively participates in your sleep: the ZEEQ smart pillow.


It’s Alexa-integrated and able to connect with other smart devices in your home, which means it can get your coffee brewing before you wake up, draw the shades back when you need to get up, change the humidity in your environment based on your sleep patterns, and heat your bathroom floor just a few minutes before you need to get ready for your day. The pillow is wrapped in a unique textile that’s antimicrobial-resistant, moisture-wicking, and cool to the touch. Perhaps the most popular feature is its ability to stream music, white noise, guided meditations, or whatever else it is you might want to hear in your own private ecosystem. With a compartment located on both the top and bottom of the pillow, you decide how much filling you want and where you want it—a feature which truly makes it infinitely adjustable.


The team at REM-Fit takes a personal approach with every customer and wants to hear feedback, whether it’s good or bad. They are constantly looking for ways to improve their product and working on the release of a new mattress line in the fall of 2019. 


Interested in learning how to get a ZEEQ pillow for yourself? Visit <a href="http://remfit.com">remfit.com</a>

The Fabulous Life of Plants – Dennis van der Wiel, Co-founder at Polariks – Advancing Technology That Can Detect Problems With Plant Health and Help Agricultural Farmers Manage Their Crops

Mar 20, 2019 26:13

Description:

Dennis van der Wiel, co-founder at Polariks (polariks.com/en/home), provides an overview of their groundbreaking technology that can help farmers assess their agriculture and improve their production. 


Polariks is all about precision agriculture and remote sensing. Polariks has developed a precision agriculture analysis method that is directly based on Hyperspectral Imaging. Their innovative technology enables better harvest planning with increased efficiency in resources, as well as early detection of diseases. And, importantly, it significantly reduces overall inspection costs.


Dennis discusses the premise of his company, Polariks, that uses reflected light to determine properties. By using their technique of light they can determine whether a plant is sick or healthy, which ultimately helps farmers to make better decisions. Dennis explains how their technology can be integrated with drone and aerial tech to make the assessments regarding agriculture.


From strawberries to grapes, Dennis discusses how their robotic and stationary systems-implemented technology can help improve agriculture and prevent outbreaks. He states that humans can easily detect coloring and other issues that could be indicative of a plant’s ailing health, but the real test comes from looking deeper, beyond what the naked eye can reveal. He outlines the infrared analysis that can assess photosynthetic activity.


The tech guru explains some of the overall goals that Polariks has in the works. He talks about the differences between outside farming and greenhouse growing. He states that greenhouses promote very homogeneous qualities and plant disease can spread quickly in a greenhouse environment. He explains that two plants side by side may both appear green and healthy, but one could already be well into a deep stage of sickness. 


This is why the Polariks technology is so useful, because the Polariks technology can identify problems with plant health several weeks before even the most trained human eye can. He explains the advanced principles of their technology and how it generates much more information that can be utilized to understand plant health.


Dennis discusses modern farming techniques and he talks about the importance of regular monitoring over time, in regard to plant disease or plant health conditions, including the effects of drought. Finally, the farming technology expert provides some thoughts on predictive modeling and other advances that Polariks expects to promote as they develop their innovative technology and platform further.

Dental Education – John Tucker, DMD, Founder of Tucker Educational Excellence LLC – Sleep Apnea and Dental Sleep Medicine

Mar 20, 2019 33:58

Description:

John Tucker, DMD, founder of Tucker Educational Excellence LLC (tuckereducationalexcellence.com), discusses sleep apnea and treatment.


Tucker is an experienced medical professional who has treated many patients over his long career, as well as educated countless dentists on dental sleep medicine. Tucker Educational Excellence provides intensive educational programs that focus on the successful implementation of dental sleep medicine practices within the dental industry. Tucker is a respected dentist and Diplomate of The American Board of Dental Sleep Medicine.


Tucker explains that dental sleep medicine focuses on treating patients who have obstructive sleep apnea and are intolerant of their traditional CPAP therapy. Tucker describes CPAP, which stands for Continuous Positive Airway Pressure, as a vacuum cleaner in reverse. 


CPAP provides a continuous flow of airway pressure to your throat to keep your airway open during sleep, which is generally successful as a means to treat the spontaneous pauses in your breath that are so often connected with sleep apnea. 


Tucker describes their process for diagnosing, which must come from a board certified sleep physician. He discusses home sleep testing, which is becoming more and more popular as it offers users the opportunity to stay within the comfort of their own home and bed.


Tucker talks about his experiences as a child, watching his father have snoring problems and extended periods without breathing. Tucker states that remarkably, some people they have seen, go up to a minute and a half without breathing when they are experiencing sleep apnea. 


The sleep expert talks about strategies to prevent various diseases; and he stresses the importance of early intervention, accessible care that is cost effective, and the family members need to be engaged. He talks about the costs of untreated sleep apnea, and the correlation with diabetes, sexual dysfunction, stroke, and GERD. 


Tucker states that 1 out of 4 Americans are undiagnosed. Tucker goes on to explain his practice and how they discover airway issues. He explains how they look into the mouth and search for what he refers to as a high-vaulted palate, as well as tongue issues, and gum issues.


Tucker Educational Excellence offers intensive learning experiences for all levels of knowledge. Their courses cover basic dental sleep medicine implementation, individualized onsite programs, as well as guided learning experiences working directly with Tucker for extended periods.

Biological Beginnings – Luis P. Villarreal, Professor Emeritus, Department of Molecular Biology and Biochemistry, University of California, Irvine – The Viruses In Our World

Mar 19, 2019 58:19

Description:

Luis P. Villarreal, Professor Emeritus, Department of Molecular Biology and Biochemistry, School of Biological Sciences at the University of California, Irvine, discusses his thoughts on viruses, life, and the changes that motivate evolution.


Is it possible to be passionate about viruses? The answer is yes. As a scientist who is constantly experimenting, with an unquenchable thirst for knowledge, Luis Villarreal is definitely passionate about understanding viruses, indeed, especially with regard to viruses that linger either in the genomes or epigenomes of their host. For over 20 years, Villarreal has centralized his study on the overall role of virus evolution on life. And Villarreal states that viruses have had a significant and profound influence on the origin and evolution of life.


Villarreal talks about his early years in science and the classes and information that truly sparked his desire to learn more, and how it organically led him to his life’s work. He details his study of negative-strand RNA viruses, viruses that resemble rabies and ebola—highly pathogenic. He recounts his observation of regulatory RNA that had dramatic consequences, which was the beginning of his true curiosity about viruses. He delves into his study of rearrangements of the genome by various types of retroviruses. He describes how retroviruses actually work together to create the placental network. He questions why this would happen, and surmises that in order for a mother or host to create life, they must take in a foreign biological entity, the embryo, and suppress its natural immune rejection, feed it, and host it for its lifespan, which requires a significant amount of change. Villarreal states that the virus footprint is literally all over all of these functions. 


The biology expert provides an overview of cellular DNA and the many jobs that DNA can fulfill. He explains how RNA and DNA react with each other and outlines their complicated network, although he states that there is much work to be done still to understand the complexity. He discusses his thoughts on human evolution and recounts stories that relate, such as endogenization of the koalas in Australia. He explains that a particular virus that was within these koalas was becoming part of them, and thus their ability to deal with the virus in their immune systems was being changed in real time. He compares this example to human development over time and discusses theories about viruses as they relate to humans, discussing the details of modification as it pertains to viruses and survival. 


His discussion of viruses and biology continues as he summarizes his thoughts on the human species and the many elements that relate to evolution and brain function, etc. On a lighter note, Villarreal muses about some Hollywood versions of viral mutations and provides his thoughts on Hollywood’s interpretation of real science turned into fiction for the movies we enjoy. He goes on to explain the astronomic scale of viruses in our environment, discussing the ocean extensively, and the microbiome. 

Sleep Rockin’– Mark Russell, Founder of Rocking Bed – Sleep and Motion, the Science Behind It and the Potential for Great Sleep

Mar 19, 2019 23:01

Description:

Mark Russell, founder of Rocking Bed (rockingbed.com), talks extensively about sleep quality, and their rocking bed that is causing a stir in the good sleep industry.


Russell is a self-described career entrepreneur, and his curiosity for creation has led him on an interesting journey in business. From small business to tree service, computers to marketing, with a little software design, advertising and sales thrown in, Russell has really done it all. In this interesting podcast, Russell talks about his exciting creation, Rocking Bed, the better way to fall asleep.


Russell discusses the bed that will literally allow you to sleep like a baby again, as it gently rocks you to sleep. Russell recounts his early experiences as a child, trying to sleep in the family car on long road trips. He talks about a cruise he went on in 2004 that literally rocked his world. As he describes, he was truly amazed by the quality of sleep he got due to the cruise vessel’s gentle rocking motion. After the cruise he was driven to find a way to create this experience in his own home, and after much study and research, Rocking Bed was born.


The sleep entrepreneur discusses various studies on movement and sleep, and explains that some studies are backing what he already knew to be true—that motion helps with sleep. As he states, the rocking motion of their product is so subtle that most people who try out their product at demo/trade shows think the rocking stops when they close their eyes, and then open their eyes quickly to discover that it’s still rocking. Russell recounts some of the stories he has heard from people regarding sleep and the rocking bed, and he talks about the immense potential for special needs children who need to be rocked to even fall asleep.


He talks about the mechanics of the bed, its movement, and the potential for helping those who have trouble falling asleep. And Russell explains some of the product tweaks that they are working on to try to keep quality high but lower the price point. Ultimately, it is Russell’s hope that they can launch the bed to a larger audience as they grow their business, and help everyone… find a way to better sleep.

Exploring the Neurobiology of Sleep—Dr. John Peever—University of Toronto Department of Cell and Systems Biology, Canadian Sleep Society

Mar 19, 2019 37:18

Description:

“Even Aristotle, over 2,000 years ago, remarked on the benefits of sleep…there’s no doubt that it’s beneficial, but we are trying to understand the specific benefits and how those benefits are occurring,” says Dr. John Peever, professor at the University of Toronto Department of Cell & Systems Biology and Vice President of research at the Canadian Sleep Society. 


It’s easy to identify the benefits of a good night’s sleep—we wake feeling more refreshed and alert, and we stay more focused and productive throughout the day—but it’s a lot harder to identify how exactly those benefits occur. Part of the investigation into this question involves understanding the neurobiology of sleep, which means understanding how different parts of the brain cause different behaviors relating to sleep.


The work being done in Dr. Peever’s lab is focused on the study of rapid eye movement sleep, commonly referred to as REM or dreaming sleep. Specifically, Dr. Peever and his team are trying to determine what part of the brain is responsible for pushing us into REM sleep, what occurs once we are experiencing REM sleep, the underlying mechanism of REM sleep behavior disorder, and why parts of brain that cause REM are so vulnerable to degenerative processes, such as those that underlie Parkinson’s disease.


Dr. Peever offers an exciting and informative conversation that touches on a range of other topics, including sleep’s potential to repair DNA damage, genetic predispositions for being a night owl versus an early bird, and the importance of understanding the true nature of narcolepsy. Tune in for all the details and learn more by visiting www.peeverlab.com.

The Lexicon of Life – John Hands, Author of Cosmosapiens:Human Evolution from the Origin of the Universe – Asking the Big Questions Regarding the Origin of Life

Mar 18, 2019 36:40

Description:

John Hands, a British author who received his scholarly training as a scientist, discusses his thoughts on the origin of life in the universe.


Hands’ book, Cosmosapiens: Human Evolution from the Origin of the Universe, is a crash course of sorts that bridges the gap between cosmology and neuroscience and hits a lot of points in between. In Cosmosapiens, Hands provides his theories on how humans evolved to be such a dominating force on Earth. It delves into current themes of study such as cosmic inflation, dark energy, and neurogenetic determinism. It examines various fields of study such as string theory and often challenges the general consensus in multiple areas of science from cosmology to biology, and even neuroscience.


Hands talks about his curiosity regarding various matters of science. He recounts how it was the passing of his wife that caused him to take an introspective look, as he began to ask big questions related to our existence on Earth, such as “what are we,” and “where do we come from,” and “why do we exist.” He explains how society has sought answers to these and other questions from the supernatural, and also from science. As a curious scientist, he was dissatisfied with the current literature on these complex subjects and decided to dig deeper on his own. He states that the specialization of science has perhaps prevented us from seeing the bigger picture as a whole. He embarked on a journey of discovery on his quest to get to the beginning of it all. He talks about some widely accepted theories in science, such as the big bang theory, that have been clearly contradicted by observation evidence. He delves into a discussion of dark matter and dark energy and explains how decades of research has failed to provide answers or evidence of what that is, leaving no scientific explanation whatsoever. He discusses the obvious fallacies in Darwinism and expounds upon the details that pertain to them. 


The scientific author explains the collaborative process that produces life and change. Continuing, Hands expounds further on his conclusion that humans are unique as a species. He states that it is actually reflected consciousness that makes humans unique. As neural complexity increased, human consciousness was created. Hands state, “We are the only species that not only knows but knows it knows.” Hands deliver an overview of ancient philosophies and other theories that make an effort to explain the origin of life. Hands talks about how it is important to admit when we do not know the answers, and though he has answered many questions about life in his book, there is so much we do not know. 


Hands talks about interesting feedback he has received from his readers, including validation of his theories from some of the world’s leading scientists and philosophers. And he talks about his plans for future works in the subjects of science.

Amid a Major Evolutionary Transition—Michael Garfield—Future Fossils Podcast, Santa Fe Institute

Mar 18, 2019 34:15

Description:

Michael Garfield is a paleontologist, futurist, evolutionary theorist, multimedia artist, and public speaker currently on the trail of a new unifying theory to explain major evolutionary transitions. In particular, he’s looking at the one he says humans are experiencing today, amidst unprecedented extinctions and innovation and rapid change—an environment that’s actually creating discomfort for many. He refers to the current major evolutionary transition as a conceptual one, whereby the human is seen not as separate from its environment or the systems around it, but embedded within its many layers. In his view, everything from single-celled organisms to the solar system itself can be seen as different layers of a single metabolic process; humans exist somewhere in between, as thinking organisms navigating their environment like any other.


He draws attention to the effect of technological advances and third-world development on the ecosystem within which we live, comments on the way in which AI and augmented reality will continue to impact evolutionary change, and challenges us to rethink the nature of our existence and perceived realities. 


Check out michaelgarfield.net to learn more about Garfield’s theories and thought processes, and follow him on Twitter and Instagram.

Wisdom Tooth Removal Replacing the Industry Standard with an Opioid-Free Surgical and Post-Op Solution—Dr. James Babiuk—The Wisdom Tooth Doc

Mar 18, 2019 23:34

Description:

It’s a procedure most people end up needing, and one that almost everyone dreads: wisdom tooth removal. But aside from the puffy cheeks and pain and misery that follow, there’s one other drawback that accompanies the standard protocol and actually threatens lives: the use of highly addictive narcotics for surgical and post-op pain management.


Dr. James Babiuk has been a practicing oral surgeon in Chicago for about 25 years now, and over time he’s noticed a marked increase in the number of people who have become reliant upon heavy-duty and highly addictive narcotics for pain management. He's seen first-hand how something as benign as a shoulder injury or back pain can result in long-term use of heavy narcotics for pain management and eventual addiction. As he began digging deeper into research regarding opioid use in the medical field, he learned that most people’s first exposure to narcotics is during and after wisdom tooth removal; this compelled him to take action.


Dr. Babiuk set out to alter his technique in a way that would allow him to perform wisdom tooth extractions without the use of IV narcotics and without having to prescribe narcotics for post-op pain management. This might initially sound impossible, but Dr. Babiuk has made it a reality—one that's proving to be incredibly effective. Rather than follow the standard protocol which is to expect and alleviate the pain associated with wisdom tooth removal, Dr. Babiuk’s approach focuses on reducing the cause of the pain, which is simply inflammation.


He joins the podcast to discuss all of this and more, including the need for medical providers to receive narcotic education and the long-term goals for his practice. 


For more information, reach out via email at info@wisdomteethjoliet.com, visit <a href="http://wisdomteethjoliet.com">wisdomteethjoliet.com</a>, or call 815-254-1560.

Master of the Tickets – Micah Hollingworth, Co-founder and CEO of BROADWai – High Tech Ticketing, Using Technology to Simplify the Ticketing Industry

Mar 18, 2019 26:38

Description:

Micah Hollingworth, co-founder and CEO of BROADWai (broadw.ai), delivers an overview of the current state of special event ticketing and the technology that drives it.


Hollingworth is a seasoned entrepreneur with over two decades of experience in creating, operating, and marketing live events. His innovative entrepreneurial skills include strategic planning, fundraising, and execution. And with an intensive fascination for all things technology it was inevitable that Hollingworth would launch another great tech-oriented business such as BROADWai.


Hollingworth talks about the many and varied interests that led him to launch BROADWai, along with co-founder, Jon Scott. He describes his entrepreneurial spirit as a child and the love for live theater he developed that led him to his current career. Moving to NYC about 25 years ago set the stage for his total immersion in the theater world.


The technology guru discusses the many challenges that people face when trying to purchase tickets for events. He states that difficulty in purchasing or reserving tickets for live events can often discourage ticket buyers, and providers may lose them to other events when the experience is arduous. Hollingworth explains how their technology platform works, and how it provides a smooth, efficient process for ticket buyers.  


BROADWai’s technology solutions assist customers with their total experience, helping them to navigate and effortlessly plan. The platform offers a valuable exchange between the guests and the Broadway community, a customized experience in one simple, single digital transaction that incorporates everything, from ticketing to parking, as well as preshow and postshow needs to provide real-time information regarding theater policies and so much more. Hollingworth discusses their integration with other ticketing partners, and the events that they currently support. Hollingworth expounds upon the future of ticketing. He states that voice-enabled devices will be a part of their future because the voice-enabled tech market is exploding. And he talks about their voice clients that will be launching later in the year. Regarding their platform, BROADWai’s AI/ML abilities continue to evolve during each conversation and with every question asked. Their innovative platform will set the bar high for competitors as BROADWai accelerates to the edge of technology and continually integrates the latest and greatest, in order to deliver a totally frictionless experience to the user.

Understanding Biological Meaning, Biological Versus Artificial Intelligence, and Evolutionary Agency—Victoria N. Alexander—Dactyl Foundation, Author of The Biologist's Mistress

Mar 15, 2019 49:59

Description:

“In biosemiotics, we say that the human ability to interpret signs—which is the ability to think really, to think creatively and adaptively and learn new things—didn’t just emerge with animals; rudimentary sign reading emerged in the simplest forms of life with single-celled organisms,” says Victoria Alexander, biosemiotician, Director of Dactyl Foundation, Fulbright specialist, and author of The Biologist's Mistress: Rethinking Self-Organization in Art, Literature, and Nature.


What’s biosemiotics, you ask? Alexander explains biosemiotics as the study of sign use in biological systems, where signs can be almost anything in the environment—a word, a pictogram, a smell, a sound, or a chemical gradient. Signs are intelligence; we can train a computer to read signs, but can we train a computer to interpret signs that depend on the context within which they exist? 


Answering this question is one aspect of the investigation into the differences between biological and artificial intelligence, which is what Alexander’s work is currently focused on. She explains that biological cells don’t just react to the chemistry around them, but interpret and respond to it. 


She goes on to explain how this underlies a system of interpretation that's related to random change in a way that’s changing the direction of evolution. In this way, Alexander argues that it is within the organism that evolutionary agency is found and explained, rather than in the mechanisms of randomness and competition.


Alexander offers an exciting and informative conversation that touches on a variety of topics, including metabolic pathways, the association of properties and the placebo effect, the idea that dysfunctional semiotic habits are the cause of some syndromes and conditions, cell differentiation, self-organization in nature, and butterfly wing pattern development. Press play to hear the full conversation.

Drug Discovery – Ilan Morad, PhD, Founder and CEO of Accelerated Evolution Biotechnologies Ltd. – How Advanced Biopharmaceutical Technology Is Making Great Strides Toward Treating Diseases

Mar 15, 2019 35:40

Description:

Ilan Morad, Ph.D., founder, and CEO of Accelerated Evolution Biotechnologies Ltd. (aebi-bio.com) discusses drug discovery and development on the cellular level.


Morad has been fascinated with biology most of his life and began practicing molecular biology and biochemistry in 1984. He is a noted expert in gene cloning, protein engineering, purification, and characterization, as well as drug discovery and development. Morad’s company, Accelerated Evolution Biotechnologies Ltd. (AEBI) is a development-stage biopharmaceutical company primarily engaged in the discovery and development of various therapeutic peptides and has developed an innovative combinatorial biology screening platform technology.


Morad discusses the origin of his company, AEBI. He details their groundbreaking screening platform and explains how it works. Their platform provides functional leads to extremely difficult targets, not merely those that best bind with the target.

AEBI’s novel technology that goes by the name, SoAP, allows them to develop drugs for many illnesses, among them cancer, and Morad expects to completely transform the drug discovery R&D phase by seriously reducing the attrition rate of any new drug candidates.


As Morad explains, peptides are microproteins. He elaborates on these and other building blocks and where they are produced and how. He discusses how they make large numbers of synthetic peptides and how they isolate them for research and development. Further, he expounds upon the roles of various peptides within the body. He discusses drug resistance, side effects of drugs, and cancer treatment. Digging deeper, he explains the properties of cancer and how the disease reacts to certain treatment, drugs, etc. Morad relates some of his thoughts on drug successes, such as the drug cocktail that has solved the problem of HIV for many patients. And as he states, drug cocktails are a possibility for other diseases. He details how cancer cells work and explains the related probabilities. 


The biology expert continues his discussion of cancer and peptides. He explains how toxic peptides can be utilized to poison cells and kill them very efficiently. This strategy shows great promise for future treatment. And he explains how immune systems work and how they recognize molecules, giving special attention to how cancer cells are targeted. Wrapping up, Morad talks about the expectations for his company and the areas they are expecting to make strides in as they move into the future. Finally, Morad talks about upcoming clinical trials and his expectations for the new cocktails and peptides. 

Self-Experiments and the Power of Data: When Medical Systems Fail to Diagnose—Damien Blenkinsopp— The Quantified Body Podcast, Ketosource.co

Mar 15, 2019 42:50

Description:

In his early twenties, Damien Blenkinsopp lived a nomadic lifestyle, rolling with life’s punches and going in whatever direction it seemed to take him. But when it took him to Thailand, it presented something which would change him forever: a mysterious illness that would leave him intermittently bed-bound and battling symptom after symptom for years on end. No matter how many specialists he visited, he couldn’t get an answer as to what was going on with his body. Not many of us have found ourselves in such a position, but the prospect terrifyingly begs the question: where would we turn for help?


Forced to answer this question for himself, Blenkinsopp embarked on a journey filled with research, self-experimentation, and conversation with any and every scientist or layperson who might provide some insight. Along this journey, Blenkinsopp created The Quantified Body, a podcast that he used as a tool for collecting information and anecdotal evidence. 


Having tried countless avenues of potential relief, Blenkinsopp can attest to his personal success with two things: the ketogenic diet and the fasting diet. He has since founded Ketosource, a website dedicated to providing others with the information and insight he’s learned throughout his journey, which continues to this day.


Blenkinsopp has a one-of-a-kind story that is simultaneously inspiring and intriguing, informative and enlightening. Press play to hear all the details, including his advice on navigating medical systems that fail to provide diagnoses, the fasting mimicking diet, and how to take back control of your health by harnessing the power of data. For resources, check out his podcast and visit ketosource.co.

Medical Crisis – Jack Rubinstein, Associate Professor of Medicine, University of Cincinnati – An Interesting Look at the Many Challenges and Problems in Today’s Medical and Pharmaceutical Industries

Mar 13, 2019 39:09

Description:

Jack Rubinstein, Associate Professor of Medicine, University of Cincinnati discusses his medical thriller, The Perfect Dose, and how it relates to real-world problems in the healthcare industry.


Dr. Rubinstein is affiliated with multiple hospitals in the greater Cincinnati area, including Cincinnati Veterans Affairs Medical Center and University of Cincinnati Medical Center. Dr. Rubinstein talks about his book, The Perfect Dose, which is a medical thriller that highlights corruption within the healthcare system, and those who threaten scientific progress. He outlines his reasons for writing the book, specifically mentioning that he thought a fictional thriller with interesting characters and story would establish a stage for societal dialogue regarding the very real, demonstrable problems within the American healthcare system. He discusses the case of Martin Shkreli, the much-maligned, now imprisoned American businessman and former hedge fund manager who sent shockwaves across the country when he raised drug prices thousands of percent. He uses Shkreli as an example of the constant battle in the industry—helping the most people possible versus helping shareholders of pharmaceutical companies make large profits. Dr. Rubinstein points out that many drugs are funded by the government agency, National Institutes of Health (NIH), which funds academia that conducts much of the research that leads to new drug development. Then drugs are often licensed to pharmaceutical companies who may charge a very high price for the drug as they sell it back to taxpayers, the very people who funded the drugs in the first place.


Dr. Rubinstein discusses many of the drugs and medical issues in his spectrum of study. He studies select drugs that have had success in specific areas of medicine and through his research has repurposed some of them for cardiovascular issues such as heart failure. He delves further into the off-label uses of many prescription drugs. Further, he expounds upon how his book highlights many issues in the American system versus other countries outside of the US. Dr. Rubinstein talks about his experiences caring for other doctors and their family members. He speaks extensively about what makes a doctor a good doctor, and the systems and standardized treatments that play a part in reputation.

Thyroid Health and A Life Well-Lived – Dr. Christianson, Naturopathic Medical Doctor – Improving the Thyroid, Adrenal Issues, and the Path to Better Health

Mar 13, 2019 41:32

Description:

Dr. Alan Christianson is one of America’s revered naturopathic physicians and the bestselling author of several books, including The Metabolism Reset Diet, the celebrated book that teaches its readers how to repair the liver, stop storing fat and lose weight naturally. Dr. Christianson, or Dr. C as many of his patients call him, provides an interesting overview of the many factors that influence good health.


Dr. Christianson is a naturopathic medical doctor, a specialist in natural endocrinology who focuses on thyroid disorders. He is extremely passionate about bringing life-changing medical information to his patients and the general public alike. Specifically, he discusses the power of diet and how it can absolutely affect your body’s hormones. An understanding of these issues provides insight into the many interrelated issues of diet, weight, and hormone balance. 


The naturopathic physician talks about the personal journey that led him to his career path. Afflicted with cerebral palsy and seizures, abysmal coordination, and the onset of obesity, Dr. Christianson had many medical and physical struggles as a child. His struggles pushed him to learn more and shift his lifestyle, which led to a new physical life and career path as well. He talks about eating well, and being active, and discusses the studies in medical school that he found particularly intriguing, such as thyroid and adrenal problems. Hormones, endocrinology, and the connection points between lifestyle and health are the basis of his intensive study. 


Dr. Christianson goes deep into an analysis of thyroid issues and explains the many problems that people can and do experience regularly. He talks about compounded thyroid medicines, and Dr. C discusses T3 in detail. As he states, T3 is a thyroid hormone that is often overlooked in basic lab work. And measuring T3 is critically important for understanding the complete functionality of the thyroid. He talks about the many medical issues that patients struggle with and how his doctors diagnose and treat the myriad of complex thyroid issues. 


Dr. C underscores the importance of optimizing blood levels and taking a serious look at everything that patients are putting in their bodies, even down to the vitamins that they are taking, some of which could even block thyroid function for those being treated. From circadian rhythms to diet, hormones, and the importance of iodine, there are many impacting factors that will definitely influence health, and Dr. Christianson seeks to spread this important knowledge to everyone, to improve lives and health.

Increasing the Accessibility and Convenience of Healthier Food Options via Gene Editing—Ryan Rapp—Pairwise

Mar 12, 2019 21:15

Description:

The power of gene editing is putting nutritious, convenient produce in the hands of people who otherwise might not have access to it. Ryan Rapp is the head of product discovery at Pairwise, a company whose mission is to utilize gene editing technology to explore collaborations focused on gene editing in the production of real crops, such as cotton, corn, and soybeans, as well as the accessibility of healthy produce options for consumers. Still, in the exploratory phase, the team at Pairwise is looking into how to help plants make the transition to the lab, which tools in the gene editing process are most efficient and effective for their goals, and how to overcome the challenges presented.


Rather than trying to breed new crops, the team at Pairwise has been focused on improving those that already exist in order to bring spectacular options to consumers. There are many products out there that hold great potential but suffer from one or more hang-ups—perhaps it’s the taste, the convenience, or the production system. Regardless of what it is, the team at Pairwise is dedicated to fixing it and maximizing consumer satisfaction.


Rapp provides a few examples of real-world results of the type of work they’re aiming to accomplish, discusses how the production of ‘baby’ carrots has significantly increased the general consumption of carrots, explains what drives their work, and what makes a plant a good food source for human food production. 


Interested in hearing more? Press play and check out their website at <a href="http://pairwise.com">pairwise.com</a>.

Addressing the Underrated Importance of Temperature In Sleep Quality—Nicolas Roux—Moona

Mar 12, 2019 23:12

Description:

As shown by many studies, a major commonality among chronic insomniacs is nighttime temperature dysregulation, preventing them from falling asleep. After beginning to explore additional research on the relationship between body temperature and sleep, it didn’t take Nicolas Roux too long to realize that temperature plays a key role in the ability to obtain quality sleep and to realize that this is a seriously underrated consideration in the area of sleep health.


He’s now the head of marketing at Moona, a company established in 2016 with the goal of developing a solution for poor sleep—something which is reported by over a third of the global population—by manipulating people’s experience with temperature before, during, and while waking from sleep. So, how are they doing it?


The team at Moona has created a pillow insert that rests in the space between a pillow and pillow case that’s designed to change temperature based on the needs of the user. The insert is connected to a bedside device that provides a constant, quiet flow of water at just the right temperature and at just the right time for an individual user. For example, cooler temperatures might be provided as someone tries to fall asleep because cooler temperatures facilitate the ability to fall asleep, and warmer temperatures might be provided before someone wants to wake up since they facilitate the ability to wake from sleep gradually and naturally, rather than jarringly from a loud alarm clock. The device is backed by AI-driven software that will provide temperature suggestions based on an individual’s sleep history data, and this is something which will only improve with an increasing amount of user data. 


This product is still in the beginning stages and there are currently only a limited number of prototypes, but feedback from user testing has been very positive, with almost everyone reporting the ability to fall asleep quicker and stay asleep longer. Roux joins the podcast to discuss all the details, including his own experience with the insert. Interested in learning more? Press play and check out the website at en.getmoona.com.

Nutrition & Disease – Andrew Koutnik, Biomedical Researcher, University of South Florida Morsani College of Medicine – Understanding the Complex Connections Regarding Nutrition, Metabolism, and Disease Complications

Mar 12, 2019 49:58

Description:

Andrew Koutnik, biomedical researcher, discusses cancer cachexia, wasting in general, the impact of inflammation within the body, and various other issues.


Koutnik is a seasoned researcher. His notable and extensive work studying nutrition and metabolism and their combined impact on health, disease, and even performance has generated much interest in the scientific medical community. He is actively involved in biomedical research with the Metabolic Medicine Lab at University of South Florida Morsani College of Medicine.


Koutnik provides an overview of cancer cachexia, which he describes as a multi-factorial, dynamic, systemic wasting syndrome. And surprisingly, Koutnik states that in spite of its long history, the condition currently has no standard of care. Cancer cachexia is often characterized by a loss of skeletal muscle mass, sometimes with fat loss, that cannot be completely reversed by conventional and standard nutritional support and can result in progressive and significant functional impairment. Koutnik explains anabolic signals and synthetic responses as well as inflammatory responses. As he states, inflammatory signals may be inhibiting the synthesis response in the muscle. Koutnik explains, by citing specific examples, the ways in which atrophy is initiated, and why it occurs. And with up to 20% of cancer patients dying of this disease, it’s clear that advanced research is needed ongoing.


The biomedical research expert discusses the process of fasting and how it affects the body. And he provides information on past research and recorded studies on ketone bodies. Koutnik explains why adipose tissue is not always used first as an energy source during fasting. He states that in a normal, healthy response to a fasting scenario or carbohydrate restriction, adipose tissue, over time, becomes a preferential fuel. He explains that while fat is a very important fuel that we also need to use intermediary metabolites. Simply defined, metabolites are the intermediate products of specific metabolic reactions that are catalyzed by select enzymes that naturally occur within the cells. Koutnik goes into detail on inflammation issues that relate to atrophy, as it is an underlying current in many of these cases though it may not always be rapid. He talks about his theories on how the body sees and understands subtle information it is receiving regarding atrophy issues. And ultimately, he states that from a physiological perspective the body will always do whatever it can to survive.


Koutnik continues his discussion on ketones. He cites various studies that provided new and significant information on ketones and specifically, exogenous esters. He explains how antioxidant responses are related to ketone presence. He states that much of the work in this area has been implemented in rodent-based studies, and now the desire is to try to translate these studies to the human scenario, and more research is needed to understand the compatibility with previous studies.

Diabetes & Diet – Andrew Koutnik, Morsani College of Medicine – Nutritional Considerations and Impact for Type 1 and Type 2 Diabetes

Mar 12, 2019 1:38:41

Description:

In this informative podcast, biomedical research expert, Andrew Koutnik, discusses nutrition as it relates to type 1 and type 2 diabetes.


Koutnik has dedicated his life to the study of the many biological factors that impact disease and their implications regarding treatment. His body of work has often focused on nutrition and metabolism as they relate to disease and general health. A significant amount of Koutnik’s biomedical research has been conducted at the Metabolic Medicine Lab at the University of South Florida.


Koutnik provides an overview of the differences between type 1 and type 2 diabetes. He states that type 1 diabetes is an autoimmune disease and the current thought is that an inappropriate immune response targets specific cells in the pancreas that produce and/or secrete insulin (beta cells). And because the immune system response has targeted them inappropriately, they are seen as foreign, thus the body may produce antibodies against them or attack them. There can sometimes be a rapid change and ultimately the body may no longer be able to manage glucose levels. Therefore insulin and glucose must be managed by the patient/doctor, as the body is negligent in its normal duties in this regard. Koutnik explains that type 2 diabetes is generally described as insulin resistance, where you have the ability to produce insulin but the body is resistant to the insulin that is present. 


Koutnik discusses the relative blood sugar levels in diabetics and various treatment protocols for both types of diabetes from the traditional to new emerging concepts. He details dietary issues for diabetics and how that relates to their insulin and treatment, with a special analysis of ketones and an explanation of ketoacidosis. Ketoacidosis is a complication of type 1 diabetes mellitus that can certainly be life threatening, a condition that results from dangerously high levels of ketones and blood sugar. Koutnik provides a granular overview of the many processes that the body goes through touching on details of elevated blood sugar, carbohydrates, molecules, proteins/amino acids, lipid molecules and more.


Delving deeper into other related issues, Koutnik talks about the relationship between sleep and glucose control. He explains how stress, caffeine, time of day, etc. can influence insulin sensitivity. 


Koutnik details the many beneficial factors of regular exercise and how it directly impacts the effectiveness of insulin. However, he stresses that with type 1 diabetes there are numerous variables that influence insulin sensitivity. Additionally, the biomedical researcher provides an analysis of nutritional guidelines for diabetics. He talks about the effects of protein and explains the kinetics of protein. He expounds upon the benefits of a low carbohydrate diet and cites his own personal success after making the shift to low carb. 


He underscores the importance of glycemic management and its great impact on the quality of life. He talks about the positive feeling that someone can get when they finally feel that they are taking control of their diabetes through diet, and succeeding! And while taking certain foods, foods we might love, out of the diet completely can be difficult, ultimately the healthy feeling that you achieve is worth the sacrifice.

On the Relationship between Ketones and Pediatric Oncology—Adrienne Scheck, PhD—Phoenix Children’s Research Institute, Arizona College of Medicine, Cancer Biology Program at the University of Arizona

Mar 12, 2019 42:48

Description:

For nearly a decade now, Adrienne Scheck, Ph.D. has focused her research on the effect of ketones and the ketogenic diet on brain tumors. As the author of Cancer and the Ketogenic Diet, senior research scientist at the Institute of Molecular Medicine at Phoenix Children’s Research Institute, research associate professor at the University of Arizona College of Medicine, adjunct professor at Arizona State University, and associate investigator in the cancer biology program at the University of Arizona, she brings an impressive amount of experience and knowledge to the discussion today.


Her research on the effect of ketones on cancerous tumors began in collaboration with Dr. John Roe, a clinician, scientist, and expert in the field who at the time had only applied the use to ketones to the treatment of epilepsy. When they studied the effects of adding ketones to an aggressive brain cancer cell line, the results were surprisingly positive: significant enhancement of the effectiveness of chemotherapy. This opened the door to many other questions yet to be investigated, such as the role of ketones as epigenetic modifiers, the confirmation of DNA within cells and how it dictates susceptibility to damage, whether or not cancer cells can use ketones as an energy source, phenotypic differences between different types of tumors, and the coming advances in technology that will lead to better data and analyses in this area.


Press play for all the details and search for Adrienne Scheck online to stay up to date with her latest research.

Developing Genetic-Based Tests for the Acceleration of Neurodegenerative Disease Drug Development—Julie Collens, PhD—Vivid Genomics

Mar 11, 2019 31:41

Description:

Over the last 20 years, there have been about 150 failed attempts to get different Alzheimer’s drugs on the market. Why? Sometimes it’s because the drugs showed toxicity in clinical trials, and other times it's because study subjects simply weren’t responding to the drugs. When the clinical target and endpoint of a clinical study is not met, the drug simply won’t move forward. But what if there are unseen variables at play that are pointing to the inefficacy of otherwise efficacious drugs? What if drugs which actually do hold great potential to treat Alzheimer’s are being rejected simply because the trials themselves aren’t being run properly, or because the right patients aren’t being enrolled?


As the CEO and founder of Vivid Genomics, these are the kinds of questions Julie Collens and her team are investigating. “There are lots of reasons why drugs can fail aside from them not working,” says Collens, as she explains how different stages and forms of Alzheimer’s can affect how a patient responds to certain drugs, as well as cognitive impairment from vitamin B deficiency, vascular dementia, or having recently suffered a stroke. Their goal is to develop and implement genetic-based tests to identify forms of variation in the disease of Alzheimer’s that are known to exist, and thereby help pharmaceutical companies run better clinical trials, perform better analyses, and get more drugs approved.


Collens describes in detail the four prototypes Vivid Genomics has already developed, how they are utilizing information from genome-wide association studies in combination with the data they’re collecting to identify predictive effects on disease, and the general challenges presented by the diagnosis and treatment of Alzheimer’s disease.


Learn more by visiting<a href="http://vividgenomics.com"> vividgenomics.com</a> and reach out via email at julie@vividgenomics.com.

Where Artificial Intelligence Meets Interior Design—Leslie Oliver Karpas—Lexset AI

Mar 11, 2019 28:28

Description:

“Democratizing access to good design is absolutely core to our mission of helping people make the world more beautiful…there are millions and millions of people out there who would like to have better design in their environments, but they can’t afford an interior designer, and for all of those people, Lexset will be a go-to,” says Leslie Oliver Karpas, co-founder of Lexset AI, a company that has built and applied an AI visual recognition system from 3D models of objects to the world of interior design.


The team at Lexset has created a synthetic data generation engine of about 80,000 different objects of furniture imaged from thousands of different angles and in different lighting conditions in order to maximize the system’s ability to recognize those objects when presented with a photo or real-world space. The system is even able to distinguish between different styles of furniture (e.g. modernist vs. industrial) and materials (e.g. wood, stone, fabric). One of the use cases of this technology is a plug-in for furniture company websites through which images of what you’d like a space in your home to look like could be uploaded, scanned by Lexset AI, and compared to the products offered by that furniture company.


Karpas offers an exciting and intriguing glimpse into what the future of interior design might look like, explaining in depth how their technology works, the positive effect of good design on people’s well-being, the objective versus subjective aspects of interior design, and use cases unrelated to interior design involving robotics.


Tune in for all the details and visit https://www.lexset.ai/ to learn more.

MyCode Biobank Sequencing Delivering Potentially Life-Saving Information to Patient Participants—Erica Ramos—Geisinger

Mar 11, 2019 23:11

Description:

Erica Ramos is the director and head of clinical and product development at Geisinger, an innovative health service organization covering about 1.5 million patients throughout Pennsylvania and New Jersey, and encompassing 13 hospital campuses, two research centers, and the Geisinger Commonwealth School of Medicine. Ramos joins the podcast to discuss the MyCode program, a research effort that began as a Geisinger biobank in 2007 and has since become a collaboration with Regeneron Pharmaceuticals to perform whole exome sequencing on the samples collected.

They very quickly realized the potential impact of the genomic information they were gathering—information with immediate medical relevancy,

such as that related to hereditary breast cancer, hereditary colon cancer, irregular heart conditions, and familial high cholesterol.


As a result, the MyCode protocol was changed in 2015 to include a return of results to patient participants for a defined set of conditions. Of the 92,000 samples they’ve sequenced, the team at MyCode has returned about 1,050 results to participants. Today, they are looking at how people respond to the information they receive, how the information is delivered, how chatbots could be used in the delivery of results to patients, and how to make genetics and genomics more accessible by primary care physicians.


To hear the full conversation and learn what’s on the horizon, tune in and visit geisinger.org/precision-health/mycode.

Biomedical Engineering for Intratumoral Drug Delivery, Tissue Regeneration, and In Vitro Disease Modelling—Jeannine Coburn—Worcester Polytechnic Institute

Mar 8, 2019 38:04

Description:

You probably didn’t realize that you’re likely wearing a material that can serve as the foundation of biomaterials used for a variety of functions, including drug delivery, tissue regeneration, and in vitro disease modelling. That’s right, Jeannine Coburn, PhD is an assistant professor at Worcester Polytechnic Institute who is altering silk fibroin—a material found in most articles of clothing—to create unique properties that could have a number of biomedical applications. In addition to silk fibroin, Dr. Coburn and her team are working with chondroitin sulfate and bacteria and plant-derived cellulose for testing methods of tissue regeneration and studying disease processes that occur in the body.


One of the main focuses of Dr. Coburn’s lab is on intratumoral drug delivery—the delivery of drugs locally inside cancerous tumors rather than systemically as conventionally done today. In order to do this, they are considering different drug delivery modifications that will allow the drugs to act more or less with the material in which they are enclosed, thereby allowing for control over the rate at which the drugs are released into tumors. In this way, the drug delivery system would mimic that of conventional practices while minimizing the many negative effects of chemotherapy on the body’s organs.


Dr. Coburn discusses the main challenge of this pursuit—namely the problem of rejection by the body. In other words, how can they prevent the body from encapsulating and attacking the drug that it identifies as a foreign body? Answering this question leads to an informative and intriguing conversation about the body’s mechanism of immune response, inflammatory responses, and how cancer cells shut off their immune recognition and how that can be modelled in vitro for the study of immunotherapy drugs used to treat cancer.


Interested in learning more? Tune in for the full conversation and don’t hesitate to contact Dr. Coburn directly by email at jmcoburn@wpi.edu.

A Pulmonologist’s Perspective on Sleep - Seema Khosla, MD—Medical Director of the North Dakota Center for Sleep

Mar 8, 2019 34:31

Description:

It might not be the first thing you associate with pulmonology, but the study of the lungs actually has quite a bit to do with the study of sleep. Dr. Seema Khosla didn’t really make this association either until she slowly began learning about the importance of sleep and the critical role it plays in our health. “It was something that I never really thought about when I was a resident,” she recalls, mentioning a time when she thought going days without sleep and pushing through it was more like wearing a badge of honor than engaging in a dangerous and detrimental way of living. 


She now serves as the medical director of the North Dakota Center for Sleep, where she sees patients who are suffering from a variety of sleep conditions ranging from insomnia, to narcolepsy, to sleep apnea, to REM sleep behavior disorder—a disorder that causes people to act out their dreams. She discusses pulmonary-related sleep issues, including poorly-controlled asthma, emphysema, and other chronic medical conditions that can cause insomnia and fragmented sleep.


She provides a glimpse into the fascinating world of sleep studies, where real-time changes in oxygen and carbon dioxide levels in the blood are correlated with real-time brain wave changes, indicating disruption from certain sleep stages. Dr. Khosla also touches more broadly on how people’s attitude toward sleep seems to be changing for the better, effective options for the treatment of sleep apnea that do not involve CPAP machines, and why so many people are initially resistant to the idea of seeking help from sleep doctors. Lastly, she discusses her takeaway from a recent conversation she had with a Fitbit representative regarding plans to further implement sleep tracking technology in their products.


Tune in for all the details and get in contact by calling 701-356-3000 

Replacing Reactivity with Proactivity in the World of Cyber Security—Dan Schoenbaum—RiskIQ

Mar 8, 2019 28:01

Description:

“Research has shown that traditional approaches in security just aren’t working,” says Dan Schoenbaum, citing large security breaches with British Airways and Target as just a couple of examples. Despite having large, sophisticated security programs, many companies simply aren’t able to prevent people from stealing their data or leveraging their websites and accessing customers’ credit card information. It’s an approach that’s been taken for the past 25 years, and according to Schoenbaum, it’s the wrong one.


When Schoenbaum discovered Risk IQ, he discovered an entirely different approach to the problem of internet security—one that focuses on what’s outside of the firewall, where the majority of attacks originate. “The heart and core of what we do is data science,” he explains. The team at Risk IQ spends their days reviewing billions of web pages, social media platforms, and mobile applications, scanning for the illegitimate ones among the legitimate.


As the COO and President of Risk IQ, Schoenbaum joins the podcast to discuss the details of all this and more, including the path that led him to Risk IQ, the ins and outs of what they offer, the changing landscape of cyber security and cyber-attacks, and what’s to come. Press play to hear the full conversation and visit https://www.riskiq.com/ to learn more. 

Comfortable, Wearable SleepPhones – Dr. Wei-Shin Lai and Jason Wolfe, founders of SleepPhones – Headphones in a Headband for Sleep, Work, Exercise and More to Improve Relaxation, Sleep, and Ease of Movement

Mar 7, 2019 19:58

Description:

Dr. Wei-Shin Lai, family physician, and husband Jason Wolfe, a video game developer, discuss their interesting and organic journey as sleep improvement entrepreneurs born out of necessity. They detail the process of how their company, SleepPhones (sleepphones.com) came to be, and discuss the many benefits of their soft, sleeping aid. 


Confronting her own problem of getting to sleep efficiently, especially after late night work, Dr. Lai explains how she sought a better solution. She often used meditative music for relaxation but found that headphones were clumsy and awkward, and ear buds were just plain uncomfortable. As necessity is the mother of invention, Dr. Lai set out to create her own. After creating the first successful working prototype of her soft, sleeping aid, she enlisted the partnership of her husband as they soldered and sewed the first 500 units right on their kitchen table. And spreading her good fortune, Dr. Lai began to provide this sleeping solution to many of her patients who suffered from bad sleep or insomnia and were regularly taking sleeping pills to assist them with sleep.



Lai and Wolfe discuss the technology behind their product. And after eleven years in business, they have continued to advance and improve their product. As they state, many people find that the SleepPhones headband is more comfortable than competitors’ products, even the much bigger companies with large revenue. 


One of the additional benefits to their product is that it is designed to sit over the ear making them supremely comfortable even for those who sleep on their side. Their super soft headband is made of their specialized SheepCloud™ fabrics, and contains very thin, padded removable speakers in which users can play any auditory preference, from music, to audiobooks, meditations, white noise, or anything else that an individual finds relaxing and helps them to fall asleep.


Dr. Lai talks about the various testimonials they have received from people who have now been able to end their use of sleeping pills. People have stated that the sleeping headphones have even saved marriages, helping people get their sleep when sharing beds with partners who snore, etc. 


Wolfe discusses some of the content providers they have worked with, and he hints about the new initiative they have developed internally that utilizes AI and machine learning to discover what sound technologies are the most effective for various applications. And Lai and Wolfe discuss the many fabrics that they offer in their products, that vary for user preferences, environments, and differing climates.

Restoring Health – Douglas W. Losordo, MD, FACC, FAHA, Executive Vice President, Global Head of Research and Development, Caladrius Biosciences – Cells, Tissue, and Repair

Mar 7, 2019 37:20

Description:

Douglas W. Losordo, MD, FACC, FAHA, Executive Vice President, Global Head of Research and Development, and Chief Medical Officer of Caladrius Biosciences, delivers a thorough overview of biopharmaceutical research and product development.


Dr. Losordo has spent decades digging deep into the many and various biological science issues that are relevant to advanced medical research. His work has made a significant impact in the areas of angiogenesis/vasculogenesis, progenitor/adult stem cells, tissue repair/regeneration, as well as vascular biology in general.


Dr. Losordo’s company, Caladrius Biosciences, Inc., is a noted clinical-stage biopharmaceutical company featuring multiple technology platforms that are specifically targeted to certain cardiovascular indications as well as autoimmune diseases. In this informative podcast Dr. Losordo gives an overview of his company’s work and their research. He states their primary objective is not to manage disease but to actually restore health. He outlines many of their late stage programs in the area of cardiovascular disease, clinical trials, and progress they have made. In prior studies they have found that just a single dose of their therapies makes people better long term. Trials are promising and he expects continued approvals as they bring more products to the market. Caladrius is committed to the development of innovative products for cardiovascular and autoimmune diseases that carry great potential to restore health to people with chronic, often severe, illnesses, to address many unmet medical needs.


The biopharmaceutical expert discusses blood vessel regeneration, and the research they are doing in this area of angiogenesis. He talks about their work with patients and how their process works, in detail, explaining how the cells are injected and how angiogenesis begins. Dr. Losordo discusses their experimentation with cells and the dramatic successes they see in the repair of ischemic tissue. Dr. Losordo talks about some of the many regulatory issues that impact the medical and biological science development industries. He outlines how their refractory angina program has been designated with a high designation for accelerated approval. 


Dr. Losordo’s successful career in regenerative medicine therapeutics has received significant backing. He has obtained over $35 million in National Institutes of Health funding for discovering and developing new therapeutic concepts in the laboratory that provide the basis for clinical studies that may lead the way to medical breakthroughs.

Getting Better Sleep – Kelly Glazer Baron, PhD, MPH, DBSM, Associate Professor, Division of Public Health, Department of Family and Preventive Medicine, University of Utah – The Importance of Sleep and Treating Sleep Disorders

Mar 7, 2019 32:04

Description:

Kelly Glazer Baron, PhD, MPH, DBSM, Associate Professor in the Division of Public Health, Department of Family and Preventive Medicine at the University of Utah, delivers a fascinating overview of sleep and its importance.


As an experienced clinical psychologist with specialty training in behavioral sleep medicine, Dr. Baron has been a leader in the area of sleep research for many years. In her clinic, Dr. Baron provides cognitive behavioral therapy (CBT) for insomnia, as well as myriad other sleep disorders such as circadian disorders, sleep apnea, nightmares, sleep walking, and narcolepsy. She received her bachelor's degree from Ohio State University then went on to complete a master's degree and PhD in clinical psychology at the University of Utah. 


The sleep doctor discusses her background and what motivated her to pursue this specific area of research and treatment. She talks about her two main areas of interest: how the disruption of sleep and the circadian rhythm can lead to the development of obesity and diabetes, and the advancement of wearables in regard to sleep technology. She talks about the benefits of wearables and how learning about your sleep can help you to improve the sleep you get. She answers questions that relate to circadian rhythms and what essentially makes one a ‘night owl.’ She explains that those who identify as night owls, the people who stay up later and then wake up later the next day, are certainly better off if they are allowed to exist as night owls as opposed to those who are night owls and are forced into a more 9 to 5 existence. However, she states that timing really isn’t the issue, but it is the alignment of melatonin and sleep schedule that impacts dietary behaviors. For example, people who force themselves to sleep earlier in their melatonin timing have greater meal frequency and tend to eat more calories, and if they are overweight… have signs of insulin resistance. Thus, ultimately, being a night owl isn’t a factor, but it’s really more about whether that night owl is forced to function in the morning. Dr. Baron states that if people find their ideal sleep schedule, and are allowed to maintain their natural rhythm, then they are probably better off than someone who is forcing themselves to adhere to a schedule based on what society says.


Dr. Baron discusses sleep loss and its affect on metabolism. But as she states, there are multiple factors that determine weight, and sleep is merely one. She does mention however, that many times late sleepers find that fitting exercise into their day is challenging, and thus needed movement may be squeezed out of their daily schedules. 


Additionally, she details sleep devices and the benefits of sleep monitoring data. And she adds that many times the data simply confirms what a user may have suspected, such as sleep is intermittent, or they are not sleeping deep enough, etc. 


In Dr. Baron’s research they are interested in helping people get rid of bedtime procrastination and other issues that interfere with good sleep. She explains the many issues and activities that may interrupt sleep or impact one’s ability to get to bed and also relax before sleeping.


Dr. Baron’s research has been generously supported by the NIH, and she has been regularly featured in top tier media such as the New York Times, US News and World Report, Men's Health, Webmd.com, and others.

Hypnotic Suggestions – Kevin Kastelnik and Guillaume Gautier, Founders of dreaminzZz – Technology and Innovation That Enables Better Sleep and Relaxation That Can Be Achieved Faster and More Efficiently

Mar 7, 2019 21:53

Description:

In this informative podcast, Kevin Kastelnik and Guillaume Gautier, the founders of dreaminzZz (dreaminzzz.com), discuss sleep and hypnosis and the benefits of relaxation for reducing stress and increasing productivity.


After many sleepless nights amidst an incredible amount of work, Kastelnik began to dig deeper into the process of sleep. He found that poly-phasic sleep (sleeping multiple times, and typically more than two) was successful, and allowed him to absorb heavy workloads more efficiently while still feeling well rested.


Kastelnik discusses his company’s vision and their primary product, HYPNOS. The objective of HYPNOS is to facilitate access and ease of use for modern hypnosis, applying it to any type of application from service, to health, fitness, or wellness. At dreaminzZz, Kastelnik and Gautier bring together technology, methods of hypnosis, and creative innovation to launch efficient alternatives to achieve their highest priorities. 


HYPNOS is the first connected hypnosis mask. It is a set of groundbreaking tools that enables users to utilize hypnosis in their professional activities, synchronized to visual and motion simulations in order to bring the benefits of hypnosis to customers.


Kastelnik & Gautier talk about the mechanisms of HYPNOS. The HYPNOS sleep mask provides light and vibration that are connected to a mobile app, which works to allow people to focus on many areas that need attention, from stress reduction to pain reduction, to relaxation, fear, and much more. 


The app will deliver hypnotic suggestions that allow the users to fall asleep or achieve their objective. They talk about the various suggestions that users can utilize, which allow users to fall asleep 3 times faster than usual. Specifically, while listening to the story in the app, the hypnotic suggestions are introduced, which as stated above, enables sleep to come faster. And with quality, restorative sleep being achieved faster and more efficiently, everyone can improve their health.


The sleep and hypnosis experts talk about the feedback they are getting from their users. As they state, sleep disorders and stress are the two main areas that their more than 10,000 users primarily tend to focus on. 


Finally, the hypnosis marketers discuss their product rollout globally, and the new, exciting products that they will be introducing in the coming years.

Reservations & Booking – Roger Sholanki, CEO of Book4Time – The App That Makes Booking and Scheduling Easier and More Efficient

Mar 7, 2019 11:12

Description:

Roger Sholanki, CEO of Book4Time (book4time.com), provides an analysis of the many issues that individuals and businesses face in regard to booking and scheduling for every industry.


Sholanki is an experienced and tested entrepreneur who has spent his career focused on disruptive companies and products that seek to improve the global health and wellness industry in general. Never accepting any given situation, Sholanki thrives on challenging the status quo, and he inspires his team at Book4Time as they set the bar higher for everything from product development to customer success. He is a pioneer in the spa and wellness industry and Book4Time is the world's most innovative cloud-based management software.


Sholanki talks about Book4Time’s objectives as a business management platform focused on the global wellness industry. He states that online booking is the preference today as call booking wanes more and more. Sholanki discusses the users’ preferences, and how users research then book their reservations. He explains the details of their app and how users can benefit from its many features. From spas in hotel resorts, to the beauty industry, wellness, leisure, and more, there are many industries and services that can take advantage of Book4Time’s platform. Sholanki provides specific examples of their wide customer base and how they each utilize the specific booking and reservation application features.

Sholanki gives specific details about the app’s features and their uses. With Appointment Booking users can maximize and grow their revenue with convenient, centrally managed guest bookings as well as optimized therapist schedules. With Marketing & Retention, the app enables users to drive revenue and retention with specialized memberships, loyalty points, and even referral incentives. Revenue Management allows every user to precisely manage and track revenues over the cloud with a sophisticated point-of-sale and payment processing system. Business Intelligence & Reporting provides for centrally managed and automated business processes and best practices. Their Staff Management feature allows users to save time on staff scheduling and bolster productivity with goal tracking, incentives and more. And their Inventory Management feature keeps everything centrally managed, so you know the inventory and can manage it for all your spa locations, and so much more.


The organizational tech entrepreneur talks about feedback from consumers and the areas of their app in which he hopes to expand. He describes certain challenges that come up in the booking process and how Book4Time is solving various industries’ problems.

Expression of Life – Dr. John Torday, MSc, PhD, Professor of Pediatrics and Ob/Gyn, Harbor-UCLA – Discussing the Intricate Details of Biological Development and Life

Mar 6, 2019 53:02

Description:

Dr. John Torday, MSc, PhD, Professor of Pediatrics and Ob/Gyn, Harbor-UCLA, Division of Neonatology, discusses biomedical research, genomics, and life.


Dr. Torday’s extensive career in medicine and education has afforded him some choice opportunities, working and researching as a faculty member at prestigious universities such as Harvard Medical School, the University of Maryland School of Medicine, and the David Geffen School of Medicine.


Dr. Torday discusses some of his early experiences in the field, as well as some of the incredible advances he has seen in science and medicine. He specifically talks about the landmark observation of his career: that the cortisol hormone could accelerate human development, which was the beginning of neonatology. The implications of this observation were immense and became the fodder for much research ongoing.


The neonatology expert comments on the vast changes in biomedical research, from biochemistry to the transition to molecular biology, and the concept of genomics. He talks in depth about the importance of epigenetics. Epigenetics is the study of heritable phenotype changes that do not require alterations in the existing DNA sequence. He muses on the concepts of epigenetics, regarding embryogenesis (embryonic development). As he states, epigenetic inheritance is passed in more than one generation, which is a particularly interesting and vital point in regard to research. He answers questions regarding genetic expression and the idea of epigenetic heritability. As he states, environment such as habitation in water or on land, play a role in organism development. And additionally, he states that diet can have an influence as well.


Speaking about evolutionary development, the PhD discusses some of his thoughts on various species, considering land and water environments. He provides extensive details on the complex biological factors that are involved. He talks in detail about three genes he states are necessary: parathyroid hormone-related protein gene, glucocorticoid receptor, and the beta adrenergic receptor.


Additionally, he expounds upon the importance of intercepting the loss of homeostatic control, which would provide for profound advances in the way we treat disease. He discusses the distinguishing traits between species, and then recounts some of the concepts and theories he has studied regarding the origin of life.

Snake Robots Are Coming! – Dragos Axinte, Professor of Manufacturing Engineering, The University of Nottingham – Exploring the World of Advanced Robotic Technology for Industry

Mar 6, 2019 22:28

Description:

Dragos Axinte, Professor of Manufacturing Engineering, The University of Nottingham, gives us a glimpse into the complex world of advanced robotic technology.


Axinte is an experienced professional specializing in manufacturing engineering. Throughout his impressive career he has held two NATO Research Fellowships in Italy and Denmark. He has been an active part of the groundbreaking research teams at the University of Birmingham as well as the University of Nottingham. Axinte was named Fellow of the Institution of Mechanical Engineer (IMechE) and Fellow of the International Academy of Production Engineering (FCIRP), and continues to contribute to the dialogue internationally in his industry.


As the prominent Director of the Rolls-Royce University Technology Centre (UTC) in Manufacturing and On-Wing Technology, Axinte works with his team to develop a range of robotic technologies that can enable engines to be inspected and repaired at remote locations, all while remaining on-wing. Axinte discusses the form and design of the robots they are creating. He mentions that they are making snake-like robots, for this design is best for entering tiny spaces that are impossible for other forms to access. He provides detailed information on how the robots access these interior spaces and exactly the kinds of jobs that they perform, such as engine maintenance, and more.


Axinte talks about the various technologies that they have developed at Rolls-Royce. He provides details on their current designs and his expectations for future redesigns and improvements. He speaks about their challenges in design and use, and the importance of making their robotic technology easy to use by untrained operators, so extensive training is not necessary. Speaking about future advances, he provides information on other operational challenges they will face in development. Axinte states that there are many opportunities to utilize their technology in the aerospace, oil and gas, and defense industries.


Axinte hopes that the future will bring more integrated use of artificial intelligence in their robotic manufacturing, and he and his team are working toward this and other goals.

Genome Exploration – Dr. Andreas Werner of the Institute for Cell and Molecular Biosciences at Newcastle University – Understanding the Vast Complexity of the Human Genome

Mar 5, 2019 35:29

Description:

Dr. Andreas Werner of the Institute for Cell and Molecular Biosciences at Newcastle University delivers a detailed overview of current research pertaining to the human genome.


Dr. Werner is skilled in many areas; he is a biochemist, molecular biologist, journalist, and teacher, currently working as an associate professor at Newcastle University specializing in RNA biology. Dr. Werner is widely known for his innovative work in the field of non-protein coding RNAs, specifically natural antisense transcripts. Dr. Werner received a PhD in Physiology at the University of Zurich.


Dr. Werner discusses his current work studying the human genome. Our genomes show small variations that make each person unique. With modern genome sequencing, the detection of mutations is now not only fast and efficient, but it is finally affordable. Dr. Werner talks about their specific work in this space. They are leading the way, investigating how mutations affect function, of various membrane proteins, in order to better grasp the underlying mechanisms of specific diseases. Dr. Werner explains transcription. Transcription is the initial step of gene expression, when a specific segment of DNA is copied into RNA by the enzyme RNA polymerase. DNA and RNA are both nucleic acids that use base pairs of nucleotides as a compatible, harmonious language. Dr. Werner and his team are particularly interested in the function of noncoding RNAs in the organization of the genome as well as the regulation of single genes.


The genome expert discusses some of the hypotheses that they are currently working on, and why. He explains cell structure and viral structure, and talks about the balance within cells. As Dr. Werner explains, double stranded RNA could possibly be a sign of low-level stress that occurs with aging, or other issue, and his team is looking for answers to multiple questions regarding links to degenerative disease. He talks about the importance of finding these double stranded RNAs to distinguish whether they are confined within the mitochondria and the nucleus or if they perhaps are leaking out and are interfering with protective mechanisms. Going further, Dr. Werner talks about specific inflammatory responses and some of the known and unknown factors regarding double stranded RNA.


Dr. Werner is a sought-after speaker at various world conferences on the subject of regulatory RNAs, epigentics and evolution. And he continues to work diligently toward the goal of deciphering a biological role for natural antisense transcripts.

The Biology of Life – Franklin M. Harold, Noted Author of The Way of the Cell--Molecules, Organisms and the Order of Life – Biochemistry, Molecular Biology, and Research

Mar 5, 2019 39:43

Description:

Franklin M. Harold, noted author of The Way of the Cell: Molecules, Organisms and the Order of Life, discusses his research in complex biochemistry and thoughts on the origin of life.


Harold’s long career has impacted many areas of science. Harold received his PhD in Comparative Biochemistry from U.C. Berkeley in 1955, and has spent a lifetime as a physiologist, specializing as a cell physiologist. It is the machinery of life, not its molecular constituents, that continues to fascinate him. As a young man, Harold was heavily influenced by the work of esteemed microbiologist, Roger Stanier, by whom he was taught that bacteria are not only the smallest creatures but also the simplest, and to truly understand life, one should study bacteria, not lab rats.


Harold talks about his long career in science and biology, starting with a passion for chemistry, which he developed at the age of fifteen. Over the years, he became more interested in cellular and evolutionary biology, and embarked on a prolific career in the scientific community. Harold discusses the tenets of Neo-Darwinism, and its need for tweaking, updating. He states that the early study was primarily focused on mutations in genes, but according to Harold, that doesn’t tell the full story. He expounds on the properties of eukaryotic cells and their origin. Eukaryotic cells contain a nucleus and organelles, and they are encompassed by a plasma membrane. Some of the many organisms that possess eukaryotic cells are as follows: protozoa, fungi, plants, and animals.


The biochemistry expert states that organisms throw off new species because their environment changes. He states that in order to see the evolution of organisms we would have to change their environment in a novel way, and give it time, lots of time. Harold remarks that the major changes that resulted in new animal species have to do with the genes that affect the web of regulation, the regulatory elements that control how much, and to what extent, a particular gene is expressed. Harold goes on to say that he believes in the theory that life must have begun with very simple chemical systems, not necessarily involving a gene, but a system sufficiently complex and interactive to be able to reproduce itself. And while he states there is zero evidence for it, nor good models, it is however a speculation that Harold finds particularly interesting.


Harold served on the research staff of the National Jewish Hospital and Research Center in Denver, and was a longtime member of the faculty at the University of Colorado School of Medicine. Harold retired from Colorado State University in 2000 as Professor Emeritus of Biochemistry and Molecular Biology.

Successful Sleep – Matthew J. Davis, MD, Associate Medical Director, Sleep Dynamics – The Importance of Quality Sleep and the Major Advances In Sleep Medicine

Mar 5, 2019 26:28

Description:

Matthew J. Davis, MD, associate medical director and section chief of the neurology division at Sleep Dynamics, discusses the importance of sleep and the sleep-related disorders that many people face.


Dr. Davis has devoted much study to sleep disorders in general, including insomnia, sleep apnea, restless leg syndrome, narcolepsy, and parasomnias. He is board certified in neurology and sleep medicine, and his extensive education includes Vanderbilt University and then medical school at the University of Buffalo. In addition to his work at Sleep Dynamics, Dr. Davis is also a respected Clinical Assistant Professor in Neurology at Rutgers-Robert Wood Johnson School of Medicine.


Dr. Davis talks about his background and the keen interest he has developed in the study of sleep. As he states, the study of sleep is multi-disciplinary; it involves neurology, pulmonology, psychiatry and psychology. Today, sleep is finally being recognized as the truly important, but once overlooked, area that it is. He discusses the technical aspects of sleep issues and the new technology utilized. And as more and more data on the subject is collected, Dr. Davis seeks to use the vast information to improve sleep quality for everyone. He talks about what a truly good night’s sleep actually means. The goal, he says, is not necessarily some externally measured parameter, but is in fact simply healthy sleep that allows an individual to function well the next day. It’s not about specific hours; it’s about an individual’s specific needs, though population data will provide guidelines that are procured from averages.


The sleep expert talks about the impact of new devices and technologies that, surprisingly, aren’t always productive for achieving improved sleep. He underscores that it is not about sleep time, but more about sleep quality. Specifically, he explains that many of the devices people use to measure aspects of sleep are really just accelerometers that measure movement and don’t really provide important data on quality or depth of sleep. He cautions that these consumer devices do not measure all the parameters of sleep in a particularly useful way. From sleep staging to breathing, eye movement, heart rate, etc., there is so much that is not being measured that is critically relevant in regard to understanding whether quality, restorative sleep is being achieved.


The sleep expert talks about home sleep testing versus sleep lab testing, and the various circumstances that unfortunately taint some of the data. And he elaborates on the future of his work and the big areas he wants to make strides in, such as insomnia improvement. Dr. Davis hopes that through further research and testing they can help provide better, non-pharmacological treatments to allow people to find their way back to quality sleep.

Anxiety & Sleep – Edward Franz Pace-Schott, PhD, Assistant Professor of Psychiatry, Harvard Medical School –Experimentation, Understanding the Connections Between Sleep and Anxiety

Mar 5, 2019 39:03

Description:

Edward Franz Pace-Schott, PhD, Assistant Professor of Psychiatry, Harvard Medical School, delivers a fascinating auditory exploration of the many issues surrounding sleep, trauma, and anxiety.


Pace-Schott has spent the better part of his notable career studying anxiety and sleep related disorders. Pace-Schott’s extensive research centers on how sleep assists humans in the regulation of their emotions and how sleep is altered in psychopathology. He is an Assistant Professor of Psychiatry at Massachusetts General Hospital and Harvard Medical School as well as the Director of the Sleep and Anxiety Disorders Laboratory. Pace-Schott holds a PhD in Behavioral Neuroscience, earned at the prestigious Boston University. 


The PhD discusses how sleep disturbance increases the risk of developing anxiety disorders. Studying people across the entire spectrum of psychological trauma, Pace-Schott looks at participants’ sleep, as well as behavioral responses to emotional memory experiments known as fear extinction and fear conditioning. By studying sleep after traumatic experiences Pace-Schott is learning more about the impact of sleep on the mental and physical. Persistent sleep disturbances can put someone at a heightened risk for developing post-traumatic stress symptoms. 


Pace-Schott details various shock-oriented experimentation that relates to fear response, called fear conditioning, citing examples such as how one might be afraid of a dark street if they had previously been attacked by a dog on a dark street. Additionally, his team utilizes experimentation techniques with fear extinction. He explains that when subjects are presented with a situation that has caused fear in the past, but now without the dreadful consequences, over time the reaction to that fear situation is decreased. Extinction, as Pace-Schott explains, creates a new inhibitory memory, that then reminds the person that this situation is not to be feared. 


The sleep expert talks about ways to utilize sleep to strengthen the extinction memory, to bolster this within traumatized or phobic individuals. He details various experimentation in this area and how these issues affect the individuals. As he explains, sleep helps to increase the participants’ ability to feel less fear about previously feared subjects. Testing provides information on the brain, body, and emotions, and the expression of circadian rhythms. They found that participants seemed to do better in the morning after restorative sleep, and retention of extinction learning. Pace-Schott’s research is highly focused on sleep's influences on evolutionary ancient learning and the myriad memory processes that contribute to human emotion regulation.

Tracking Transactions – Dan Abbate, CEO and Cofounder of EIGHTY ONE-c – Blockchain, Security, Crypto, and the Future of Transactional Business and Accounts

Mar 4, 2019 23:16

Description:

Dan Abbate, CEO and cofounder of EIGHTY ONE-c (81-c.com), provides a complete overview of blockchain, security, and the new developing markets.


Abbate is a skilled entrepreneur and investor who has specialized in business process automation via advanced technology and organizational development. Throughout his illustrious career, Abbate has helped many innovative businesses overcome systemic challenges and advance forward with important, critical decisions regarding growth, revenue, operational performance, automation, profitability, systematization, organizational improvement, and much more. Abbate earned a degree from DePaul University in Philosophy and Business, and has continued his education at The Wharton School studying complex operations and financial performance.


Abbate talks about his background in 90s internet tech and how he organically moved into the crypto and blockchain area. He connected with the early movement and kept his eye on the crypto markets all along. He explains how he knew the underlying technology of blockchain, with its simplicity for ensuring security, would eventually come to dominate certain areas of transactional business.


Abbate discusses the many and varied regulations that have shaped the industry. He discusses the regulatory space in detail, and explains how it hasn’t really changed with the times. He explains the structure of his company, 81-c, and its primary objectives. Since its inception in 2016, 81-c has sought to acquire solid companies that generate cash flow, and improve them. But in 2017, Abbate made the decision to securitize their portfolio and build an operating company that was backed by the new blockchain technology. And in 2018, as the SEC stepped in and made everything a security, it became clear that they could take their operating company and utilize the blockchain to push forward in transactional business.


Blox is aware that there is a tremendous amount of value created in the world that simply isn’t accessible to most people. Thus blox is continually seeking ways to allow everyone to have a fair and equal opportunity to invest in the success of the world’s greatest thinkers, innovators, and entrepreneurs.

Crypto Asset Tracking – Alon Muroch, Cofounder and CEO of Blox – Keeping Your Accounts Clean, Safe, and Secure—Cryptocurrency, Blockchain, and Beyond

Mar 4, 2019 26:06

Description:

Alon Muroch, cofounder and CEO of blox (blox.io), talks about the current state of cryptocurrency, blockchain, and the new advances in portfolio management.


Muroch talks about his background in development and coding and how he discovered blockchain by accident. He recounts his early experiences seeking out a way to transfer money more effectively. Fast forwarding to the future, Muroch discusses how his company was created out of his own organic need to find a better way to sync various wallets and exchange accounts into one place, to better manage his assets.


Blox is more than numbers and charts; it is an incredibly efficient system that helps to provide a clearer image of your crypto assets. Muroch’s company, Blox, has developed the most advanced, organized crypto currency asset and portfolio-tracking platform in the entire industry. The blox platform enables users to track, collect past transactions and pricing automatically, and more, by connecting directly to tens of blockchains as well as up to date crypto currency exchanges.


Muroch discusses the many potential problems that could arise when ordering one’s books, regarding taxes and auditing. As he states, even a small error could become a giant problem when dealing with financial issues, and mistakes can be made easily. Even the practical side of daily transfers can be a place where mistakes happen. Muroch talks about transactional data, and how to make it robust and complete, and the importance of reporting and bookkeeping to ensure all records are intact. The financial technology expert provides a wealth of information on the future of blox and their work with accounting firms.


As Muroch explains, blox provides many tools to assist with accounting and for regulation compliance. He provides details on some of the plans blox is developing, from the re-imagination of transactional data to feedback-based development in the areas of wallets, ledgers, and high-level security features.

Human Physiology – Michael J. Joyner, MD, Researcher, Noted Expert on Human Performance –Understanding Physiology, Performance, and Blood Flow

Mar 1, 2019 50:26

Description:

Michael J. Joyner, MD, physician, researcher, and noted expert on human performance and exercise physiology delivers an overview of the extensive study and research he has embarked upon throughout his long career in the field.


Dr. Joyner has spent a lifetime studying the human body and how it performs and functions. Through his impressive research studying exercise physiology he has made significant contributions to the greater understanding of muscle and skin blood flow, as well as blood pressure regulation, and of course athletic performance. 


Dr. Joyner has been a respected consultant to the National Institutes of Health (NIH) as well as NASA and the groundbreaking research at his Mayo Clinic lab has been funded by the NIH since the early 90s. In this informative podcast Dr. Joyner talks about integrative physiology, how humans respond to complex challenges, and the limits of perspective. He discusses blood flow and the restorative properties of systems. He recounts some of the past experimentation regarding blood flow and circulation. He delves into detail about angiogenesis, which is the physiological process by which new blood vessels begin to form from those preexisting vessels already present, and formed in the initial stage of vasculogenesis. The doctor talks about gene therapy and drugs that have been used to stimulate blood vessel growth, but he stresses that the best means for achieving this goal is actually exercise.


Dr. Joyner discusses drug repurposing, and the history of various notable drugs that have found their purpose later, after development and trial. He talks about some of the early experimentation and important studies regarding bed rest, and how we have learned that we need to, in most cases, mobilize people as early as possible right after medical procedures and operations, etc. He expands on his thoughts about progress made in the surgical environment, and the future of technology—and how it can help us to improve. And he rounds the discussion back to his primary area of study—physiology and human performance, which he has studied intensively since the 80s. 


The human performance expert discusses the latest findings regarding glucose and physical exercise. He states that exercise is really the key to fighting prediabetes and diabetes, and its effects are powerful. He discusses various trials, and drug development for many medical conditions, and the evidence that supports some of the new blood pressure controlling type drugs. 


The prestigious Mayo Clinic named Dr. Joyner a Distinguished Investigator in 2010 and his lab provides major educational opportunities for students and trainees, as it continues to further the dialogue on human performance.

Dental Care, Digital World – Brian McCarthy, Executive Vice President, Dentistry.com – Using Technology and Communication to Advance the Oral Care Industry, Connect Patients to Doctors, and Improve Wellness

Mar 1, 2019 27:07

Description:

Brian McCarthy, Executive Vice President, Dentistry.com, provides an extensive overview of the current state of dental care.


As the operational leader of Dentistry.com as well as the Executive Vice President at Futuredontics, Inc., McCarthy has spent many years advancing the field of modern dentistry. His vision and strategic execution of goals has helped to deliver value to dentists and patients via the design and creation of multiple products that push interactions, leading to better quality dentistry for all.


McCarthy talks about a growing epidemic in the United States—the lack of oral care. McCarthy states that many Americans are simply not taking care of their teeth, and as the connection between oral care and overall wellness is significant, this is a problem. He talks in detail about how dentists in particular have been slow to adapt to the mobile web and have not taken full advantage of changes in technology. Interestingly, he mentions a study that showed 67% of US adults will expect to be able to book their healthcare appointments entirely online—by 2019. The future of online access is here, but the vast majority of dentists don’t support online booking. Seeing this need, McCarthy sought to make dentistry more accessible for everyone. In any given year, less than half of the population goes to the dentist, and McCarthy states that this is a problem Dentistry.com aims to correct. 


The dental care entrepreneur talks about the many advanced products that have been developed in the dental industry, from clear aligners to other orthodontic products and more. He discusses new equipment that reduces risk, and the great advances that are happening in tooth repair. McCarthy discusses preventive care in detail, and explains how modern dentistry can offer improvements in the arena of oral care. Today, dentists offer so many features in their offices that make the experience calmer, more fun, and sometimes even spa-like. As he states, it is the age of the consumer, and businesses that recognize that are moving ahead of their competition and excelling in the industry. 


And McCarthy talks about the inclusion of texting technology in the marketing efforts of many dental offices. He discusses how the concept of teledentistry can improve patient/doctor relations. Teledentistry is the use of various information technology and advanced telecommunications for dental care consultation and education. While McCarthy is careful to point out that teledentistry is certainly not a replacement for office visits, it is an opportunity to have more direct contact with those who care for your teeth, an opportunity to learn more, and to motivate individuals to work toward improving their overall oral care.

Adolescent Health, Obesity, and the Latest in Sleep Technology—Dr. Conrad Iber—University of Minnesota and Fairview Sleep Center

Feb 26, 2019 29:07

Description:

Dr. Conrad began his career studying patterns of sleep interruption and doing work in various areas of epidemiology, and lately he’s been working to improve population health and sleep conditions while entering the realm of policy and population management within larger healthcare systems.


More recently, he’s been working in conjunction with the University of Minnesota on the evaluation of school start time issues and the connection between sleep, obesity, and adolescent health. “Adolescents have by nature a delay in their sleep schedule, beginning roughly around the age of 12…independent of their tendency to surf the internet and study late into the evening, there’s perhaps a stronger drive to go to bed later and get up later,” says Dr. Iber. As quasi-experimental evidence of this, some schools that have tried out later start times have seen better academic performance, fewer car accidents, improved moods and attention spans, and better overall sleep health. Conversely, a study out of Fairfax, VA found higher suicide rates, weight gain, and decreased academic performance among adolescents who regularly get fewer than five to six hours of sleep. So, why haven’t widespread reforms been implemented?


Dr. Iber provides the answer to this question and many others, discussing a range of topics to include the latest advances in sleep medicine, such as the increased use of home monitoring and wearable devices to track sleep duration among patients who can’t make it to a sleep clinic for in-house studies. He also touches on the increased emphasis being placed on police officers, health care providers, bus drivers, and other public service members to improve their sleep health. According to Dr. Iber, there is a growing awareness and acceptance of the importance of sleep, which is nothing but positive for individuals and public health in general. Interested in learning more? Press play for all the details.

Intelligence Augmentation—Alex Bates—Author of Augmented Mind, Co-Founder of Sandbox, and Director at Neocortex Ventures

Feb 26, 2019 23:57

Description:

Ever since he was a kid, Alex Bates held a fascination for the inner workings of the mind and brain, and the interconnectedness of philosophy and mathematics. So when the internet began really taking shape in the late 90s, it only felt natural for him to dive into the realm of artificial neural networks. He’s since devoted his professional life to anything and everything that revolves around artificial intelligence and machine learning.


Bates discusses his role as co-founder of Sandbox, a company designed to support engineers by providing mentor networks and developing an investment and incubation community around AI and machine learning for B-to-B enterprise software. Among other topics, he explains the types of entrepreneurs they are best suited to help and the criteria they look for when making selections.  


But before Sandbox, Bates was involved with Neocortex Ventures. “You can think of Neocortex Ventures as like an idea laboratory, where I have data scientists help people build ventures and I can invest as well,” says Bates. He goes on to discuss some of the most surprising and impressive recent developments in the field of AI and machine learning, including generative adversarial neural networks and the fascinating results that can emerge, such as turning artistic paintings into 3D immersive videos, and the way in which this technology underscores the value and extent of human creativity as complimentary to AI--the combination of which leads to what he calls ‘intelligence augmentation.’ Press play for more.

Catastrophe Calculations – Peter Saunders, Co-Director of The Institute of Science in Society, London – Understanding the Practical Applications of Catastrophe Theory

Feb 26, 2019 54:40

Description:

Peter Saunders, Co-Director of The Institute of Science in Society, London, and Emeritus professor of Applied Mathematics, King’s College London, provides a thorough and interesting overview of catastrophe theory and its many real and relevant applications.


Saunders holds a BA in Applied Mathematics from the University of Toronto as well as a PhD in Theoretical Astrophysics from the University of London. He is a sought-after lecturer and keynote speaker and has presented his findings and theories for many groups and events, notably at Queen Elizabeth College and then at King’s College.


Saunders discusses the etymology of the word, ‘catastrophe,’ and discusses the background of catastrophe theory. Saunders explains that catastrophe theory is a theory that allows us to deal mathematically with things that change suddenly. And as he states, things that change suddenly are often the most interesting. He details catastrophe theory, explaining that if you have a system that is displaying certain jumps of one kind or another that these jumps will occur in a pattern. Saunders outlines the five basic properties that tend to go together: sudden jumps, hysteresis, divergence, inaccessibility, and bimodality. As Saunders explains, when you observe one, you begin looking for the other four. He talks about the many applications of the theory and how it enables researchers to come to conclusions within their research.


Saunders explains that when a researcher is considering what has been observed, he or she makes a statement, and what is most desired is a theory that enables one to take that statement, that is based on observable actions, and do something with it. He discusses the relevance to applied mathematicians, and elaborates on how they seek to utilize what they do know, and little else, so their applications are based on truth. Saunders discusses the many possible applications for catastrophe theory, and he specifically talks about utilizing the theory to study important issues such as climate change. He provides interesting examples, regarding extreme fluctuations and how they can be indicators of increasing instability in regard to climate changes. As he explains catastrophe theory doesn’t provide absolute proof, but in fact it only provides signs and indicators. Saunders states that if you want absolute proof, the only way to get that is to sit back and let something happen, but by then it will be too late to prevent that ‘something’ from happening.


Saunders’ groundbreaking book on the subject, An Introduction to Catastrophe Theory, breaks down catastrophe theory for everyone, even those who may have only a basic understanding of mathematics. The book explains the basic tenets of the theory and discusses practical applications, often citing biological science examples due to their particular ability to demonstrate catastrophe theory’s distinctive nature. The celebrated book is a good read for theoretical biologists, scientists in general, and anyone who has an inquisitive mind and seeks to learn more about the theory and its applications.

Lynn Caporale

Feb 25, 2019 52:29

Description:

Jen Fisch - Founder, ketointhecity-com (RJ)

Feb 25, 2019 23:01

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Keith Baverstock.

Feb 25, 2019 38:07

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Gabriele M. Barthlen, MD, PhD

Feb 25, 2019 28:05

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Foot Fantastic – Emily Splichal, Podiatrist, Naboso Technology – Foot Stimulation For Multiple Improvements In Health

Feb 25, 2019 23:15

Description:

Dr. Emily Splichal knows all about your feet. In fact, she has spent a lifetime studying feet, in her practice as a successful podiatrist, and also as a foot technology entrepreneur. In this podcast we’ll learn all about the foot and the many benefits we can get from understanding what its nerves are communicating.


Dr. Splichal spends her time helping people with their feet in a clinical setting as a podiatrist, but also helping them by developing new products that provide for better posture, rehabilitation, wellness and more. Her work in the field is innovative and she is a leader in the research of movement dysfunction and neuromuscular issues.


Dr. Splichal discusses her company’s many products that improve health. The company she leads is Naboso Technology, which offers the preeminent line of insoles and mats designed for increasing ease of movement and improving posture.

As she states, Naboso’s prime objective is to improve foot function and foot stimulation from a neurosensory perspective.


The foot physician talks about the texture of their Naboso insoles and she explains how the insoles create powerful stimulation and provide benefits that everyone can experience. Dr. Splichal explains how their products work to improve neuro rehabilitation and wellness, and can assist with podiatry and orthopedics issues, pediatric development and more. She details the ways nerves in the foot relate to our posture and movement, and she explains just how important our feet truly are. If you thought feet were just for walking, then tune in to this podcast and discover the amazing truth about the power of the foot.

The Potentially Life-Saving Benefits of Human in Vitro Technologies In Lieu of Animal-Based Product Safety Testing—Dr. Ellen Berg—Alto Predict

Feb 25, 2019 37:23

Description:

“As we have learned more and more about the mechanisms of toxicity and drug mechanisms, we’ve come to appreciate how different… people are from animals, and it makes us realize why drugs still fail 30% of the time for safety in people,” says Dr. Ellen Berg, reflecting on the current state and usefulness of animal-based drug testing. For many years, product developers and the pharmaceutical industry has relied upon the assumption that what’s toxic to non-human animals is more likely to be toxic to human animals; while this is true, it is not the best we can do, it does not account for the growing number of differences being identified between the animal model and human being, and it comes at a price.


As the founder of Alto Predict, it is Dr. Ellen Berg’s goal to introduce alternative approaches to product safety testing that remove the animal model and replaces it with human in vitro technologies, such as organs-on-chips, organoids, bioprinted tissues, and stem cell-based assays. She explains that despite many innovative advances in these methods over the past decade, there’s been a significant lag in adoption by product developers. Why?


According to Dr. Berg, the answer is multifold, but one of the primary reasons is because validation data showing predictivity of the assays is either limited or simply hard to access. This means that those who critically need this data in order to feel confident in moving forward with adoption of these technologies simply don’t have it, and don’t have an easy way to obtain it. The same type of problem exists with animal testing data but for different reasons: “A lot of in vivo animal data is in silos within pharmaceutical or consumer products companies and nobody has access to it, so…the lack of predictivity of animal testing has been hidden,” explains Dr. Berg.


Alto Predict is addressing this problem by building a platform that provides easy access to human in vitro technology validation data, alongside specialized analytics and data visualization tools as a way to bring business intelligence analysis to complicated scientific data. Having spent the last 15 years developing this platform, Dr. Berg has discovered many novel mechanisms of toxicity that are contributing to the safer selection of molecules with assay predictivity.


The team at Alto Predict is currently working on the beta version of the platform and have already partnered with Collaborative Drug Discovery to showcase various in vitro assays relevant to cardiovascular toxicity. Tune in and visit altopredict.com to learn more.

The Physics of Life – Adrian Bejan, J.A. Jones Professor of Mechanical Engineering at Duke University – Science and The Origin of Living Things

Feb 22, 2019 54:03

Description:

Adrian Bejan, J.A. Jones Professor of Mechanical Engineering at Duke University, delivers a thought-provoking analysis of the mechanics of life, energy, and the science of our natural world.


Bejan is world renowned for his pioneering work in engineering and applied science. Specifically, his extensive research has delved deep into multiple areas of science—engineering and applied physics covering thermodynamics, heat transfer and convection, as well as design and evolution in the natural world. Bejan has been celebrated for his work, receiving 18 honorary doctorates from prestigious universities around the world, and he has authored 30 books and in excess of 650 articles on various subjects in his many areas of expertise. His recent book, The Physics of Life The Evolution of Everything, is considered a must-read for the scientific community and anyone who is interested in practical science and the origin of living things. 


Professor Bejan delivers a robust overview of the areas of practical science that are misunderstood, and some that are simply incorrect. Bejan lists a few of the commonly held theories that are inaccurate: that nature is complicated, that we cannot predict nature, and that we are threatened by a population explosion. He cites specific examples that prove his theories about the aforementioned. He states that many of those who speak about science publicly are not actually trained in science. As such, ideas can float around in the public discourse that may not be based in hard science. 


The engineering and science professor discusses thermodynamics, which is, as he describes, everything that has to do with movement—movement that comes from power, with the power coming from burning fuels, etc. Two things are certain: thermodynamics is about everything, and changes are occurring continually in science. The physics of evolution is constantly pushing all life and manufacturing to become a better version of itself. Changes occur, and science is the reason. Professor Bejan talks about the details of the physics of evolution, touching on the topic of power, as he states that nature is full of engines. He details the structure of the greatest engines of Earth. The earth, as an engine, drives our atmosphere and heating from the sun and cooling by the sky drive the earth engine. And this immense power delivery drives all the things on Earth. 


Bejan explains energy within animals and life in general. He talks about the elements of life and predictable design in nature. He states that much in science is recognizable and easy to draw, and all too often we overcomplicate the basic elements and structures of life. Bejan talks about the meaning of the word evolution, and how it is used in every language in western civilization and was certainly not invented or coined by Darwin. Bejan speaks of evolution as a ‘moving forward’ that assures us that tomorrow will be different than today—the future will be different than the past.


Professor Bejan talks about the laws of physics as they relate to evolution, and how the laws of physics help us to see oneness in nature as opposed to blinding complexity. Further, Bejan discusses our organic preference for certain forms in nature, such as the golden ratio. As he explains, there is a globally accepted preference for forms due to the fact that certain shapes are the easiest to be perceived and scanned by the human eye. From business cards to flags to computer screens, we have shaped our world with the shapes that the physics of our humanity prefers. 


Professor Bejan continues to explore his interests in thermodynamics and applied physics, as well as evolution in nature, and his work is pushing the scientific world forward, advancing the understanding of life itself.

Genetic Gateways – Kenneth Weiss, Penn State Department of Biology – The Quest for Answers About Genetic Variation

Feb 22, 2019 42:11

Description:

As an interested scientific mind, Kenneth Weiss has been fascinated by biology and genetic research through his long career in science. In this podcast, the Evan Pugh Professor Emeritus of Penn State’s biology department discusses genetics and variations.


Dr. Weiss has spent years studying the effects of genetic variations and how they impact disease. He details how genes play a part in the development of complex traits such as blood pressure and diabetes, as well as many other health issues. He provides his thoughts on the current state of genetic prediction and explains why there are significant difficulties in precision genomic medicine that relate to a myriad of impacting factors such as where we live, climate, diet and nutrition, one’s occupation, and much more. Genomes, as he states, are different from person to person, and thus interpreting general information through the use of finite genomic data is not necessarily highly accurate. 


The gene expert lays out his theories on gene repair and discusses CRISPR technology, a technology that assists scientists to alter a DNA sequence and modify gene function, which many have touted as the next great leap in medical advancement. But Dr. Weiss stresses the complexity of these issues due to variations from person to person.

Providing the Tools for Citizen and Community-Led Science—Sharon Terry—Genetic Alliance

Feb 22, 2019 24:18

Description:

There are approximately 10,000 known diseases affecting modern humans—about 7,000 of which are rare, and about 3,000 more which are common. Each and every one of us is susceptible to developing or contracting a disease at any point in our lives, and most of us will. And once we do, then what? Where will the resources be?


The team at Genetic Alliance is working to make those resources comprehensive and easily accessible by the community in the form of biobanks containing tissue and blood samples, information on the progression of diseases, data on treatment methods and drug therapies, and statistics correlating phenotypic and genotypic traits. They are a 32-year-old non-profit initially established to help other non-profit disease advocacy groups work efficiently and effectively, but over the years they have worked increasingly toward creating and raising awareness of the benefits of disease registries and biobanks. Not only do they allow individuals to decide the way in which their data will be used, but they are making it easier than ever before to share that data by providing non-profit advocacy groups with free sample collection kits.


Sharon Terry, CEO of Genetic Alliance, joins the podcast to discuss all of this and more, including large-scale genome sequencing, the stratification of drug therapies, FDA interest in various gene therapy/editing registries, and at least one aspect of Genetic Alliance’s mission that doesn’t sit well with some academic institutions.


Search for information on any of the 10,000 diseases by visiting diseasinfosearch.org, and learn more about Genetic Alliance by visiting <a href="http://geneticalliance.org">geneticalliance.org</a>.

Delivering Compliant and Secure Cloud-Based Automated Solutions to 500,000 Professionals Worldwide—Eric Cutler—Abacus Next

Feb 22, 2019 1:17:28

Description:

Abacus Next is the only fully-integrated technology as a service solution provider on the market, and their cloud-based solution is helping a wide range of professionals manage and automate the complexities specific to their business in a compliant and secure way. They specialize in helping companies that work in highly regulated industries that deal with protected and sensitive client data, and they’re not new to the field—they’ve been in business for 35 years now, evolving alongside the changing landscape of technology, and servicing about a half million business professionals across the globe.


One of their main products is the Abacus private cloud, which helps professionals get off IT and enter a full-managed private cloud, and another one of their main products is HotDocs, a document automation and assembly platform that’s currently being used by four out of the five largest banks in the world. While they primarily service professionals in the legal, accounting, finance, insurance, and government realms, their customer base ranges from Fortune 100 companies to small and medium-sized businesses.


Chief Marketing officer, Eric Cutler, has been a member of the team at Abacus Next for several years now, and joins the podcast to discuss all the ins and outs of the services they provide, including the tailored platforms they have for subsections within the legal profession—a profession that’s particularly complicated, varied, and immersed in highly sensitive data. Interested in learning how Abacus Next may be of service to you or your business? Tune in and visit https://www.abacusnext.com/

A Philosopher’s Insight on the World of Biology and Communication—Günther Witzany—Biocommunication and Natural Genome Editing

Feb 22, 2019 39:34

Description:

Gunther Witzany’s original area of expertise was the philosophy of language, which brought him into the world where philosophy and the sciences meet. After reading many biological papers and noticing that they used many of the same terms to describe the behavior of organisms, such as cell-cell communication, genetic code, translation, and encryption, he realized that biologists were trying to use communication and language in a mechanistic way. According to Witzany—and the general conclusion of a 60-year-long discussion in the philosophy of science—this is an error simply because language and communication cannot be explained by mechanistic terms. Why?


Witzany offers his answer to this question, and in doing so, gives his account of his concept of life as a communicative structure, meaning that organisms and their components communicate through processes and sign-mediated interactions, much like one might describe parts of human communication. He discusses the three levels that exist in every language, the role of epigenetic markings in the expression and transcription of DNA, how viruses edit code and why more of them are our friends than enemies, and whether viruses or cellular life emerged first.


Tune in and learn more by visiting biocommunication.at.

Reversing Diabetes with a Simple Diet Change—Dr. Adam Nally—Author of The Keto Cure and Founder of Docmuscles.com

Feb 22, 2019 50:13

Description:

With a family history of diabetes, heart disease, hypertension, and a variety of other metabolic syndrome problems, Dr. Adam Nally tried to keep his calorie count low and exercise five to six days a week, but it wasn’t working: he was still 65 lbs overweight, his triglyceride levels were almost four times what they should be, he was prediabetic, and he was always hungry. As a practicing family medicine physician, he was noticing the same patterns in many of his patients. “I started looking for answers for myself and for my patients, realizing that what I was taught in the traditional school just was not effective,” says Dr. Nally.


This search led him to the most recent research on obesity, which led him to eventually compile a plethora of information on the many hormones used by the body in order to control weight and the powerful influence of food on hormonal behavior. For the past 15 years, Dr. Nally has implemented everything he’s learned into his practice, removing starches and sugars from his patients’ diets and replacing them with fats and proteins. The results? He’s helped reverse over 50 cases of diabetes and continues to treat 16 diseases that respond very well to the removal of starches from the diet. The Keto Cure: A Low Carb High Fat Dietary Solution to Heal Your Body and Optimize Your Health is all about Dr. Nally’s experience over the past 15 years treating patients with this diet and “walking the walk.”

3D Printing Revolution – Nathan Wilmot & Keith Wilson, Dow Industrial Solutions – Advances in 3D Printing Processes and Materials That Are Improving Manufacturing Efficiency, Quality, and Accessibility

Feb 19, 2019 28:55

Description:

Nathan Wilmot, associate R&D director, and Keith Wilson, strategic marketing manager, of Dow Industrial Solutions, discuss the launch of their new 3D printing product. They provide a wealth of information on the many ways 3D printing is revolutionizing product manufacturing, and they discuss in detail—additive manufacturing.


Additive manufacturing utilizes data computer-aided-design (CAD) software or advanced 3D object scanners to conduct hardware to deposit material, via layering, in exact geometric shapes. Wilmot and Wilson talk about their work with Dow, specifically in manufacturing, regarding additives or ingredients that impact the way that water interacts with materials in a wide variety of areas such as breweries and wineries for their cooling and thermal stability, to concentrated solar power and renewable energy, etc. They talk about the innovations that they are looking to bring to the concept of additives, specifically in regard to 3D printing. They state that the company’s strength lies in the polymer space, and that is currently their primary focus. Wilmot and Wilson talk about their product launches and the development of prototypes. They discuss the filament type printers that many people use, and the new technology and new materials that are improving mechanical durability and performance. Additionally they outline how some of the new materials may require a learning curve to fully understand how to work with them, but ultimately the effort is needed in order to continually advance the 3D customized printing revolution that is upon us. 


The manufacturing experts detail some of the ways that they hope to bring products to the market faster and more efficiently. They discuss the issues that they hear about through their close contact with the industrial community at large, and how Dow has continually worked to meet the needs of the community and not only solve the problems, but ask the questions that can keep them ahead of the curve as the technology changes rapidly. Wilmot and Wilson detail some of the opportunities to streamline production of parts via 3D printing. As they state, in many cases the processes that are used in injection molding, etc. utilize materials that are specific to those processes, thus Dow is seeking to make the necessary adjustments to materials, etc., to meet the needs of the new manufacturing wave.


Finally, Wilmot and Wilson discuss some of the new development in their industry and they talk about where the industry is headed as additive manufacturing evolves. Dow is striving to develop ways to make 3D printing scalable, and offer new solutions to improve mechanical performance, to increase accessibility to products in remote areas, and improve materials so they can withstand environmental conditions. 

Biological Phenomena — Christopher Barrett, PhD, Biocomplexity Institute & Initiative — Biocomplexity, Answers Leading to Questions and More Answers As Scientists Seek To Understand the Myriad Pathways to Disease

Feb 19, 2019 45:20

Description:

Christopher Barrett, PhD, is a distinguished professor and the executive director of the newly established Biocomplexity Institute & Initiative at the University of Virginia. Dr. Barrett talks about biocomplexity and the premise of his work.


Dr. Barrett is an established interdisciplinary computational scientist. Over his illustrious 35-year career he has published more than100 research articles examining many aspects of various scale interaction systems. Dr. Barrett is celebrated for his outstanding work, and for founding some of the most notable national and international technology programs of their kind. He has worked with the Department of Defense, the Department of Energy as well as the Department of Homeland Security.


Dr. Barrett states their mission: to look at massively interacting systems, systems built of extremely large numbers of interacting heterogenous pieces. From cells within our bodies to the cellular machinery involved, to ecology and life on the planet, and more… the Biocomplexity Initiative will cast a wide net as they study many and various systems. He states they are focused on practical applications in important areas such as epidemiology, bioinformatics as it relates to nucleotide sequences, and to basic public policy and how it affects human health.


The biology and infectious disease expert discusses how population and other social determinants, sanitary practices, etc. impact the spread of disease. He talks about infrastructure modeling, health modeling, and economic variables that are studied to see the bigger picture and make assessments about possibilities.


The Biocomplexity Initiative provides high-performance computing capabilities that will assist researchers as they develop a greater understanding of the complex relationship between human genomics, behavioral aspects of health, as well as the environmental effects, in the myriad ways that diseases may exhibit. Dr. Barrett discusses their disciplined approach that seeks to forecast, explain, and visually present the behavioral interactions of substantial, highly complex systems. Dr. Barrett’s long-term mission is to enable research and help researchers to get a better grasp of how diseases spread based on various factors such as cultural behavior, specifics of a pathogen, human transportation of disease, and other important issues. And the ultimate goal of the work is to be prepared for the worst-case scenario—global pandemic.

Biological Changes – James A. Shapiro, Professor of Microbiology, University of Chicago – Active Biological Functions and a History of Evolutionary Theory

Feb 19, 2019 54:25

Description:

James A. Shapiro, professor of microbiology with the department of biochemistry and molecular biology at the University of Chicago, provides an overview of how organisms adapt to change.


Since 1973, Shapiro has been helping to shape the field of microbiology. In fact, he was a member of the initial team to successfully isolate a single gene from an organism. With a long history in the study of bacterial genetics, Shapiro has helped to craft the concept of natural genetic engineering, a process of biological evolution. As a supporter of non-Darwinian evolution and outspoken critic of the modern synthesis, Shapiro has published many works in the field detailing his analyses of the various related subjects and topics.


Shapiro discusses his basic thoughts on the concept of evolution. He provides a historical analysis on the theory that random mutations and natural selection are the essential elements of evolutionary change, and states that not only is this an oversimplification—it is inaccurate. As Shapiro states, many active biological functions are taking place, and accidents are not necessary for evolution; essentially, organisms can create their own evolution when challenged. Shapiro details some of their early experimentation with bacteria in the study of antibiotics. He states that they found in their experimentation that mutations in bacteria were able to allow bacteria to become resistant to antibiotics.


The microbiology expert talks about symbiotic organisms such as the microbiome, which contributes to properties of the larger organism. He discusses what happens in cells and the cellular activity that creates change in organisms. Specifically he discusses mitochondria and DNA sequences and the relational aspects in terms of biology. He explains how disparate organisms in our bodies share the same genome, yet they have different characteristics. Epigenetic changes determine which regions of the genome are being expressed. Epigenetics, simply stated, is the study of heritable changes within gene expression that do not involve any specific changes to an underlying DNA sequence, and as such affects how cells can then read genes. As he underscores, organisms sense changes and adjust to them. And interestingly, as Shapiro states, bacteria and cells in general are keenly aware of what is happening in their environment.


James Shapiro’s latest book, Evolution: A View from the 21st Century, discusses his thoughts on new ways to understand the tenets of biological evolution.

Toxic Algae Bloom, Carbon Fixation, and Potential Fuel Sources—Dr. Ben Long—Australian National University College of Science

Feb 18, 2019 44:01

Description:

In comparison to most plants, cyanobacteria are simple and easy to work with—after all, they can be grown in glass tubes. However, there is a lot that is still unknown about them, and as such, they’re the focus of a great deal of research. Dr. Ben Long received his PhD in plant biology from La Trobe University in Australia where he spent time as an undergraduate and post-doctoral student studying cyanobacteria and trying to identify all the compounds they produce. In particular, he’s looking at the type and quantity of toxins and other bioactive compounds they produce and what can be learned about these compounds. For example, just within the last several years, cyanobacteria have been shown to produce an amino acid that may play a role in neurodegenerative diseases.

Dr. Long brings a wealth of interesting information to the conversation on today’s podcast, detailing cyanobacteria biochemical reactions previously thought to be nonexistent, discussing the difference between the way plants and cyanobacteria fix carbon dioxide in the environment, mysterious toxins called microcystins produced by cyanobacteria, the photosynthetic efficiency of C4 plants, and the application of cyanobacteria compounds in bioreactor work, such as the ability to produce oils from them that could be used as a form of fuel.

Tune in for the full conversation and learn more by searching for RIPE photosynthesis on the web and visiting http://photosynthesis.org.au.

Sleep Matter Initiative—Dr. Stuart Quan—Brigham and Women’s Hospital, Division of Sleep and Circadian Disorders

Feb 18, 2019 34:49

Description:

“Sleep affects everybody; we sleep for one third of our lives, it’s the one activity we do the most of, and it’s the one thing that if we don’t do well or long enough, will have significant repercussions on our health, on our quality of life, and on others,” says Dr. Quan, Clinical Chief and Medical Director of the Division of Sleep and Circadian Disorders at Brigham Women’s Hospital. With over half of the American population reporting that they don’t get enough sleep, he argues that sleep deficiency has become an epidemic. While many people dismiss the importance of sleep, studies have shown that regularly getting fewer than six hours of sleep per night increases your risk of heart disease, stroke, high blood pressure, and diabetes, while lowering your overall quality of life and putting other people’s lives in danger.


Dr. Quan and his team are working to combat this problem with the Sleep Matters Initiative, which involves giving presentations about sleep health at various institutions and organizations, as well as administering screening questionnaires to all audience members after each presentation. If someone’s answers on the questionnaire suggest that they might have a sleep issue, then the Sleep Matters Initiative will help them contact the right healthcare provider in order to have their sleep further evaluated.  


Tune in to learn more from Dr. Quan, visit www.brighamandwomens.org to find the clinic and make an appointment, and learn more at<a href="http://www.understanidngsleep.org"> www.understanidngsleep.org</a>.

Genetic Generation — Kamal Obbad, CEO and Cofounder of Nebula Genomics — The Mysteries Revealed Through Genomic Data

Feb 18, 2019 27:28

Description:

Kamal Obbad, CEO and cofounder of Nebula Genomics (<a href="http://nebula.org">nebula.org</a>), delivers a thorough overview of the current state of genomic data, research, and what the future holds for the study of the genome.


As a self-described Harvard graduate and Cambridge University computer science dropout, Kamal Obbad has definitely taken his own path to success. Obbad is a passionate biotech entrepreneur whose keen interest in both tech, and helping others, led to his cofounding of Nebula Genomics.


Obbad discusses the mission of his company—to make genomic data extraordinarily useful for medical researchers. Getting their start at Harvard Medical School in the lab of fellow cofounder George Church, known as the "father of synthetic biology,” the entrepreneurs set out to expand the opportunities for genomic data to be used. From data driven clinical decision making to drug design, Obbad discusses the possibilities. He provides detailed information on sequencing genomes, explaining how a genome can be read, and what information can be gathered through the process.


The science tech entrepreneur talks about how genomes are utilized in the study of diseases, and the mechanisms of genetic change. Obbad states that there are many barriers to getting genomic data, from regulation to personal fears about revealing one’s genomic data. Genomics, specifically stated, is the interdisciplinary field of biology that focuses on the structure, mapping, function, evolution, and editing of genomes. And a genome is an organism's comprehensive set of DNA that includes all of its genes. Obbad discusses data sets that are accessible and the challenges to gather the appropriate amount of data in aggregate. Obbad states, when individuals use genetic data companies such as 23andMe and others, to gather personal information they are curious about, what the individuals are really doing is paying these companies for the privilege to resell this genetic data.


Because of the many aforementioned problems and challenges, Obbad and his co-founding partners have decided to take Nebula Genomics in an entirely different direction, better for everyone involved. As they state, the future of health is in your DNA. Nebula Genomics allows users to contribute to significant medical breakthroughs and get rewarded for it, unlike other companies who may sell your data and provide you with no real compensation in any form. Nebula Genomics stands firmly on the idea that everyone should understand their genes, and truly own their personal health data. As such, Nebula Genomics has reinvented the genomic data business model, utilizing blockchain to connect data buyers with data users, and liberating genomic data by bringing records to a single network where researchers can gain critical access.

Robotic Sensors as the Eyes and Ears of New Jet Engines—Dr. James Kell—Rolls-Royce Engineering Company

Feb 15, 2019 28:23

Description:

Rolls-Royce is an engineering company that makes jet engines which get distributed all over the world for use in land, air, and sea. Some engines made in the 1960s are still in use, and they aren’t actually that different from the engines being made today—that is, with one main (and important) exception: they weren’t designed with service or repair ability in mind. Without this design, repairs can be time-consuming and cost hundreds of thousands of dollars. This is where the importance of keyholes—small holes through which repairs can be completed in the field—on jet engines becomes particularly important.


As a technologist at Rolls-Royce engineering company, Dr. James Kell explains new ways of allowing more service ability with these engines, and how this challenge has spurred new projects and designs for the construction of jet engines. For example, the team at Rolls-Royce has already created engine health monitoring networks capable of monitoring an engine’s temperature, pressure, and vibration. The newest project in the works is a permanently embedded camera network that would provide an unprecedented amount of insight into the functional health of the engines that the world so heavily relies upon.


Tune in for all the details on this intriguing topic. To learn more, visit the media section of the Rolls-Royce website at <a href="http://rolls-royce.com">rolls-royce.com</a>. 


Sleep & Technology — Sandeep Jain, MD, Pulmonary and Sleep Medicine Specialist — Medical Technology Advances for Sleep, and Controlling Access & Delivery of Your Patient Information

Feb 14, 2019 28:57

Description:

Sandeep Jain, MD, FCCP, pulmonary and sleep medicine specialist, as well as the founder of ListenMD, discusses sleep issues and disorders, and the technology that is helping patients who suffer to get the care they need.


ListenMD is an intelligent, innovative universal health care communication platform centered on patients that have been specifically designed for doctors and nurses, their staff, caregivers and patients alike. The platform minimizes tedious tasks and expands a doctor’s time while improving care, and—saving money. The HIPAA compliant messaging app is easy to use and it allows a patient to control access and view their appointments with physicians or other healthcare providers. More information can be found online at listenmd.com. Since the dawn of medical records, maintaining accurate information has been challenging. Jain discusses ways that ListenMD can help. As Jain explains, patients are now able to use their app to put them in the center of the data collection process, which improves their chances for better health.


Jain stresses the importance of communication in health care, especially in regard to sleep. Regarding patient care, Jain states that patients need to be looked in the eye and talked to directly so they can get the attention they deserve. Jain talks about obesity rates, how they are increasing, and thus—so is apnea. 


Jain talks about the advances in auto-titrating CPAP devices used by some patients with sleep issues. He explains how the technology can vary the pressure and deliver the best breathing possible for each patient, tailored to their daily needs. CPAP is an acronym that stands for Continuous Positive Airway Pressure therapy. CPAP is a useful treatment for obstructive sleep apnea. A CPAP machine contains a hose and mask, or sometimes a nosepiece, and it can deliver a steady air pressure to control breathing and keep it regulated.


Finally, Dr. Jain provides some real advice for those who are concerned that they may have a sleep disorder, and what they can do about it. And he underscores the importance of quality sleep, and the dangers we face in our daily environment if we are performing activities, especially driving or operating machinery, when sleep deprived.

Future Web is Now – Gabriel Rene, Director of VERSES Foundation – Spatial Web, How Tech Advances Such As Virtual Reality and Artificial Intelligence will Impact our World

Feb 14, 2019 41:24

Description:

Gabriel Rene, an architect of the spatial web, director of VERSES Foundation (verses.io), delivers an overview of the current state of technology, including AI and product interfaces as we move to a Web 3.0 world. 


Gabriel Rene is excited about technology. As an experienced deep technology entrepreneur and researcher, he has been a leader in the technology, telecom, and entertainment industries for over 25 years. Rene has helmed innovative tech companies, and has been instrumental in developing consumer software. He has advised many leading industry brands including Verizon, Sony, Coca-Cola, Apple, Samsung, Microsoft, Intel, Qualcomm, Universal, Boost Mobile, Conde Naste, Elle Magazine and even the Obama Campaign. 


Rene talks about the history of humans and our relationship to information, transitions, and experiences. He provides his thoughts on evolution and the progression of man in regard to communication, from early years all the way up to the computer revolution that is now powering a multi-trillion dollar economy progressing through Web 2.0 developments. Web 2.0 refers to websites that push user-generated content, simplify use, etc. As the web develops, Rene states that we are moving toward spatial web.


Rene explains how the current AI boom will transition everything in our world into smart, autonomous, and self-programming products and devices. Blockchain and cloud-enabled systems and services will be able to support a secure data layer, and new virtual as well as augmented reality eyewear advancements will provide an opportunity to truly interface with an exciting, digitally-mapped, changing world, bursting with visual imagery and details never before seen.


Rene’s company, VERSES, is a non-profit foundation that is producing the universal protocols and standards for the next-generation web. No longer tied to a page, the Spatial Web will exist freely, as a single, worldwide network that can creatively link people, places, and things—in the virtual and physical realms—and enable flowing interaction, transaction, as well as full and immersive navigation between them for a more advanced way to experience our daily lives.


Rene discusses the many regulatory issues surrounding data and privacy, etc. In Web 3.0, he states, the risks must be mitigated, and security must be built in to protect privacy, etc. He explains that a type of digital force field will be utilized to implement protections and securities for all of our products within our space, to control the information that is going out. Ultimately, as Rene states, much regulation will be needed, and that we will need to hold our elected officials accountable to implement laws that can help us all to enjoy the technological advances while keeping our privacy secure. 

Nano Nano – Trevor Morin and William Dunbar of Two Pore Guys, Inc. – Nanotechnology Opens New Opportunities in Research

Feb 14, 2019 29:12

Description:

Trevor Morin, PhD, CSO biochemistry, and William Dunbar, PhD, cofounder and acting CEO, of Two Pore Guys, Inc., provide an interesting overview of nanotechnology as it applies to scientific advances.


Morin and Dunbar’s company, Two Pore Guys, Inc., is literally transforming human and environmental health by bringing nanotechnology and precision science together to detect and quantify biomolecular targets. 


The science and technology entrepreneurs discuss their products and advances in nanotechnology in regard to agriculture, human, and animal use cases. They discuss nanopores, which are sort of like tiny gateways that allow only one molecule to proceed through at a time. As they explain, this ‘passing through’ process allows for information to be gathered in detail. The sweet spot for their technology, as they explain, is identifying pathogens based on their DNA or RNA-specific sequence.


Specifically, Morin and Dunbar’s, Two Pore Guys, Inc. is a team of biochemists and engineers who work together to develop groundbreaking technology. Their innovative single-molecule-sensing platform can provide the precision, accuracy, and sensitivity of reference lab equipment while saving time and money.


The scientific pathology tech guys elaborate on how they solve problems built into field-deployable products. With singe molecule counting using an electrical output they find that their accuracy is heightened, with extremely sensitive reagents. Their breakthrough technology allows for superior detection of multiple infectious agents. Their device differentiates among a whole suite of infectious diseases with improved time performance. Additionally, as they explain, the Two Pore Guys’ platform eliminates the need for complex instrumentation and chemistries, and again, is more cost effective than traditional methods used currently. And in regard to quantifying genetic variants, their outstanding platform can detect and quantify cancer variants from liquid biopsies with the precision of droplet digital PCR, and again, at a faster rate and reduced cost than traditionally used methods.


The science innovators discuss their timetable for revealing more of their product line. As they explain, their beta unit will be available in less than two years. Morin and Dunbar are excited about the possibilities and their continual advancement of products that can enhance scientific and medical innovation.

Cancer and Bone Marrow Fat Cells New Research on the Mechanism and Treatment of Multiple Myeloma—Michaela Reagan—Maine Medical Center Research Institute

Feb 13, 2019 33:39

Description:

Quite a bit is known about bone-building cells (osteoblasts) and bone-resorbing cells (osteoclasts), but not much is known about bone marrow fat cells—aside from the fact that bone marrow becomes packed with them as we age or become obese. We also know that there is a correlation between the incidence of multiple myeloma (a type of blood cancer that affects the bone marrow) and age, and multiple myeloma and obesity. This naturally poses the question, how might bone marrow fat cells be connected to or aid in the development of the tumor cells seen in multiple myeloma?


This is precisely what Michaela Reagan, PhD and her team at the Maine Medical Center Research Institute are investigating. She joins the podcast today to discuss a variety of interesting topics, including the details of this research, the process of multiple myeloma, how tumor and non-tumor cells enter the bloodstream from the bone, the parallels between bone cancer and osteoporosis, epigenetic changes in tumors, and where her research is headed. Press play for all the details and learn more by visiting mmcri.org and clicking on Dr. Reagan in the faculty list.

Surprising Insights from a Facial Plastic Surgeon—Howard David Stupak, MD—American Board of Facial Plastic and Reconstructive Surgery

Feb 13, 2019 35:27

Description:

Turn on the TV or flip through the latest celebrity magazine and you’re almost guaranteed to find a blurb or picture of the latest botched plastic surgery or rumors about a celebrity’s suddenly changed look. Why are these stories so commonplace—particularly the plastic-surgery-gone-wrong stories? Wouldn’t these millionaire celebrities be able to afford the best out there?


Dr. Howard David Stupak joins the podcast to provide his answer to these questions, discuss the ironic reality and misconceptions surrounding plastic surgery, and touch on a range of topics in the field of plastic and reconstructive surgery. He specializes exclusively in cosmetic and reconstructive surgery of the face, head, and neck is board-certified by the American Board of Facial Plastic and Reconstructive Surgery and is known for his delicate technique and natural-appearing results.


To get in touch and find out more, contact Dr. Stupak’s Connecticut-based private practice at 203-227-1826.

Silkworm Cocoons Aiding in the Surgical Repair of Injured or Diseased Tissues—Whitney Stoppel—Stoppel Lab, University of Florida

Feb 13, 2019 38:21

Description:

The Stoppel Lab at the University of Florida opened its doors and accepted its first Ph.D. student just a few months ago, but they’re already knee-deep in an exciting endeavor which could aid in the repair of injured or diseased tissues in patients: designing natural material that has the same characteristics and structure of natural tissue and is constructed to match the wound healing rate of different patients with different injuries or illnesses.


While other scientists may be working on similar projects, the Stoppel Lab is going about this in a unique way, by using a natural biopolymer extracted from the cocoon of silkworms. When these cocoons are washed, broken down into viscous solutions, and made insoluble, they can be used to create fully formed scaffolds which will be used in different tissue structures. The acellular platform being created has many beneficial characteristics that make it convenient for use in the surgery room. For example, it’s easy to sterilize and easy to store, which means it doesn’t have to be made on demand.


Whitney Stoppel, Ph.D. runs the Stoppel Lab and joins the podcast to discuss all the ins and outs of the chemistry and physiology behind the work being done and the greatest challenges faced so far. Press play for the full conversation and visit<a href="http://www.stoppellab.com"> www.stoppellab.com </a>to learn more.

Sleep An Undervalued, Misunderstood Human Necessity—Michael Howell, MD—Sleep Performance Institute

Feb 13, 2019 43:55

Description:

“Poor sleep is pervasive in our culture and is thought of as being…dispensable, and this has consequences that range from motor vehicle accidents to cancer,” says Michael Howell, MD, and co-founder of Sleep Performance Institute. He’s been practicing sleep medicine for years now and realizes all too well how many people don’t consider their sleep challenges serious enough to seek help when in most cases all they need is a bit of knowledge and understanding in order to identify and fix their sleep issues. He also realizes the widespread impact of poor sleep on performance in general, and the Sleep Performance Institute focuses on helping organizations achieve their best performance by helping their employees achieve the best sleep.


Dr. Howell offers an impressive amount of information on everything sleep, including natural circadian rhythms and how they vary from individual to individual, the circumstances under which overnight work schedules can be detrimental, the process of lymphatic clearance during sleep, what happens during REM versus non-REM sleep, circadian realignment strategies, why many people don’t enjoy or aren’t hungry for breakfast in the morning, and tips on achieving just the perfect nap. 


The team at Sleep Performance Institute is developing a web-based application that will help people better understand their natural circadian rhythm, which is the first step to achieving better sleep that’s more aligned with the needs of individual bodies. Tune in for all the details and visit <a href="http://sleepperformanceinstitute.com">sleepperformanceinstitute.com</a> for more.

Sleep & Recovery — Dr. Charles Samuels, Medical Director, Centre for Sleep & Human Performance — Sleeping Well, the Key to Good Health

Feb 12, 2019 26:06

Description:

Dr. Charles Samuels, M.D., CCFP, DABSM, is devoted to a good night’s sleep—for everyone. He has committed many years to the study of sleep and recovery and in this podcast, he outlines the importance of sleep and what to do when our sleep is suffering.


Dr. Samuels is a board certified sleep medicine expert, certified with the American Board of Sleep Medicine, as well as the medical director of the Centre for Sleep & Human Performance in Calgary. As a top researcher he has been a primary player in multiple clinical trials from Phase II to Phase IV, and he has worked with some of Canada’s extraordinary athletes on their sleep and recovery.


Dr. Samuels talks about his motivation for getting into the sleep research area, and he recalls a particular night in which he was driving on a low amount of sleep and nearly drove into a lake. From that brush with danger, he was alerted to the true power of sleep and the dangers of inadequate sleep in regard to performance. He decided to dig deeper and began to research more, which led to his development of a passion for sleep science.


Dr. Samuels’ lab, The Centre for Sleep & Human Performance, offers study and consultation for sleep apnea, sleepwalking, insomnia, narcolepsy, sleep phases, movement disorders, sports performance, etc. The sleep guru provides an overview of occupational medicine, and makes a point about workweeks, stating that companies should limit employees’ workweeks to the 40 to 48 hours per week range to ensure their greatest chance for safety and good health. Dr. Samuels outlines proper training and recovery for professional athletes, and great options to help them recover, and maintain better overall health and extend their professional careers in their chosen sport or competition. As president of the Canadian Sleep Society, Dr. Samuels has a responsibility to public health and he works tirelessly to provide the general public with valuable information on sleep and recovery to help them help themselves—and achieve the best health possible.

E. Deorbit: The Space Debris Removal Mission—Luisa Innocenti—European Space Agency

Feb 12, 2019 36:22

Description:

Just like human activity has resulted in pollution on Earth, it’s resulted in the pollution of the space around Earth, leaving large volumes of space debris in orbit—debris ranging in size from a few millimeters to dead satellites weighing thousands of pounds. While even the smallest sizes of debris pose the threat of colliding with active satellites and causing damage—indeed, a piece of debris measuring just 0.7 mm recently caused a European spacecraft to lose power—the larger items of debris pose the additional threat of what’s called the Kessler effect, which occurs when the collision of objects in space results in a chain reaction that can eventually render an orbit nonoperational.


Head of the European Space Agency (ESA) Clean Space Office, Luisa Innocenti, joins the podcast to discuss all the details of the problem with space pollution, catastrophic collisions, preventative measures that are currently being taken in order to avoid collisions, and two possible ways to clean up the orbits we so heavily rely upon one that involves a net, and one that involves the use of a robotic arm moving in synchronicity with space debris.


Press play for the full conversation on these important topics and <a href="http://visit https://www.esa.int/ESA">visit https://www.esa.int/ESA</a> for more information on the ESA’s current projects.

Re-Working the Notion of Evolution—Perry Marshall—Evolution 2.0

Feb 11, 2019 53:44

Description:

Author of Evolution 2.0: Breaking the Deadlock Between Darwin and Design, creator of the Evolution 2.0 podcast, and electrical engineer Perry Marshall joins the podcast today for a compelling and exciting conversation about everything life and evolution, offering his opinion on questions concerning the origin of new species and the origin of life. 


He discusses a variety of topics along the way, including plant versus animal hybridization, symbiotic mergers, the cognition and intelligence of cells, Donald Williamson’s theory about metamorphosis, CRISPR gene editing, epigenetics, and emergent properties. The overarching and perhaps most surprising message of all is that the theory of evolution is in the process of being completely re-worked…leaving us to question nearly everything we’ve held true for decades. This isn’t one to miss, so tune in and learn more at<a href="https://evo2.org/evolution/"> https://evo2.org/evolution/</a>.

The Internet of Things — Zach Supalla, Founder and CEO of Particle — Controlling Our Environment and Our Products with Technology

Feb 8, 2019 27:40

Description:

Zach Supalla, founder and CEO of Particle (<a href="http://particle.io">particle.io</a>), provides a detailed overview of how technology is improving the ways we can interact with and control our devices and products.


Supalla’s company, Particle, is the dominant IoT platform on the market that simplifies building, connecting and managing internet-connected hardware products rolled out on a large scale. IoT, as it is typically referred to stands for ‘the Internet of things’ and is the comprehensive network of devices such as home appliances, vehicles, etc. that contain electronics, software, actuators, and of course connectivity which allows them to connect, interact directly, and exchange their data. Particle’s innovation has truly taken business by the hand and is leading the industry toward a more connected world. And their numbers are astounding as Particle is used by more than 150,000 developers in over 100 countries and, impressively, by 50% of Fortune 500 companies. 


Suppalla discusses the way his company works. Particle is the technology partner that provides the software and hardware to connect products to the internet, which allows for collection of data from the physical device and thus control it remotely. As mentioned, building an IoT product begins with getting a device online, Particle has simplified the process because all their hardware is specifically designed to get devices connected in minutes via Wi-Fi, cellular (2G/3G/LTE), or even mesh (MCL), a technology that allows a computer’s user to easily connect to an advanced wireless mesh network that utilizes Wi-Fi or WiMax. 


Suppalla talks about some of the companies that they have worked with that bring real world problems to the table, problems that Particle can help to manage. He discusses one particularly interesting company called Opti that provides a truly effective and incredibly efficient solution to address stormwater runoff and protect valuable water resources. Opti’s stormwater management system is in place all over the world. Opti, as Suppalla explains, has a system that can ‘connect’ to a city’s pumps and valves to dynamically move water, so as a storm is approaching the system can move water around as needed. Opti allows for reservoirs to be controlled, to prevent flooding. 


Suppalla talks about some of the industrial uses of the technology such as controlling fans for crop protection during a frost. While these niche industries may seem like they are too small to be concerned with in terms of the technology, they are actually very big, and technology can provide many solutions to these niche industry real world problems. 


Further, Suppalla talks about the importance of reliable connectivity. He gives examples of how important and critical messages can be missed when connectivity is lost, even if only for a few minutes, or even seconds. Discussing the IoT world, he states that there are many and various different problems that exist and Particle seeks to intercept problems, find solutions, and improve our lives through the use of technology. 


Suppalla is a recognized authority on the Internet of Things and is a sought-after speaker for many technology events such as Web Summit, OSCON, Solid, GMIC, and Launch. Suppalla holds an MBA from the Kellogg School of Management and a master’s in engineering management from the McCormick School of Engineering at Northwestern. 

Disorders That Affect Our Sleep – Dr. Martin Scharf, Research And Development Consultant at Cleveland Sleep Research Center

Feb 8, 2019 36:55

Description:

Dr. Martin Scharf, Ph.D., FABSM, sub-investigator, research, and development consultant at Cleveland Sleep Research Center, delivers an overview of sleep research, and drugs for treatment of various illnesses including fibromyalgia.


Dr. Scharf has a passion for sleep, and don’t we all! A good night’s sleep is one of the best experiences you could hope for, and unfortunately… something that many of us don’t get consistently. Dr. Scharf’s passion for sleep goes beyond simply wanting a great night’s sleep however, as he has devoted his life to the study of sleep and works tirelessly to treat people at his clinic to help them achieve better health through quality sleep. Dr. Scharf began his sleep research at UCLA, where he worked under the direction of Dr. Anthony Kales, a true pioneer in sleep medicine. Dr. Scharf continued his education and received a Ph.D. from the Pennsylvania State University in Hershey. Throughout his long career, Dr. Scharf has had a hand in the development and testing of almost every significant pharmaceutical used in treating disorders of sleep and wakefulness. He has published over 250 scientific papers. Additionally, Dr. Scharf was the creator and director of a freestanding sleep disorders clinic in the US (Tristate Sleep Disorders Center), the first of its kind.


Dr. Scharf discusses the many issues regarding fibromyalgia, its common symptoms and why the condition is misunderstood. Fibromyalgia syndrome may cause chronic widespread musculoskeletal pain that can often be associated with fatigue or other symptoms. The pain fibromyalgia sufferers feel often includes increased sensitivity in areas called tender points. Dr. Scharf provides details on the connection between fibromyalgia and the binding of Gamma. Gamma hydroxybutyrate, as it is called in its more formal name, abbreviated simply as GHB is a known chemical found in the brain as well as some other areas of the body. Gamma can also be made in a laboratory setting. It is used for depression, weight loss, and relief of several troublesome fibromyalgia symptoms such as pain, fatigue, and sleep problems. Dr. Scharf recounts his long extensive drug testing studies working with patients that led to a drug treatment for narcolepsy. But Dr. Scharf knew that GHB had further uses and he continued his studies. He recounts how he discovered that it increased deep stages of sleep and the release of growth hormone. Armed with this knowledge he began to look for medical conditions or disorders that would be a match and he made the connection to fibromyalgia. He talks about some of the amazing improvements that patients began to see in regard to better sleep and reduced or nearly eliminated pain. 


Further, the sleep research expert talks about his other studies and clinical trials that led to new developments and treatments. He recounts the moving stories of some of the patients that testified during FDA hearings regarding GHB. Many of those who testified stated that they never wanted to return to their life the way it was before treatment with the compound. He relates a wealth of information about the controversy surrounding the drug and why date rape concerns kept the drug from being welcomed into the legitimate medical industry for much longer than it should have been, given the fact that it showed profound and dramatic improvements in those who suffer from fibromyalgia. 

Scientific Theory — Dr. Bruce Damer, Scientist, Designer, Author, Founder and CEO of DigitalSpace — The Origin of Life and Virtual Space Exploration

Feb 7, 2019 36:26

Description:

Dr. Bruce Damer, scientist, designer, author, as well as founder and CEO of DigitalSpace (<a href="http://digitalspace.com">digitalspace.com</a>), provides a thorough overview and analysis of the origin of life as well as his vast experimentation in the area of physics-based simulations for space research.


Dr. Damer is a distinguished computer scientist and active associate researcher in the Department of Biomolecular Engineering at the University of California at Santa Cruz. Dr. Damer’s work with Prof. David Deamer led to the publishing of “Coupled Phases and Combinatorial Selection in Fluctuating Hydrothermal Pools: A Scenario to Guide Experimental Approaches to the Origin of Cellular Life” and, an article in the journal, Life, “A Field Trip to the Archaean in Search of Darwin’s Warm Little Pond.” Their collaborative research, work, and publishing has created a surge of new interest in the subject of life’s origin and kept the scientific community buzzing.


Dr. Damer talks about the origin of life and his theories. He discusses Darwin’s “warm little pond” theory, which Dr. Damer and Prof. Deamer have updated. As he explains, when you have a situation in which warm water is filling up an area, then draining, in a cyclical way, this creates an opportunity for life, an opportunity to make all sorts of biopolymers in a primordial soup as he refers to it. He discusses his research and experimentation that was able to create RNA, which is a necessary polymer of life. 


Dr. Damer’s company, DigitalSpace is an innovative international corporation with a focus on the creation of virtual worlds for industrial design engineering, education as well as public outreach. In fact, it was DigitalSpace that produced notable first rounds of internet-based 3D avatar applications. From virtual events and tradeshows to advanced learning spaces for K-12 and college, complex corporate information sharing spaces for efficiency, and of course virtual worlds for artists, DigitalSpace is innovating in multiple industries.


The science expert states that the barriers to creating lifeforms in a lab are time and the amount of experiments that would be necessary. He theorizes that life often tried to start then failed over historical time periods. He details random selection and mutation, and the power of a network. He describes in detail the network effect, and elaborates on progenotes, which are the last universal common ancestors, also called the last universal ancestor. Thus, as he theorizes our common ancestor was actually a network.


Dr. Damer recounts many and various experiments that he has been involved with in regard to life and its origin. He provides a detailed overview of experimentation that has occurred regarding 3D modeling and physics-based simulations for a wide range of space missions, and he talks about their upcoming work with cubesats, which are miniaturized satellites for space research.


Since the beginning of the 21st century, DigitalSpace has been an important player in key contracts with Adobe, NASA and other federal agencies, as well as prime contractors to produce a myriad of advanced virtual environments for space mission design and training, and so much more.

The Dietary Genetic Link — John O’Connor, Founder of Gene Food — We Are, Literally, What We Eat – Cracking the Genetic Code to Improved Nutrition

Feb 7, 2019 26:07

Description:

John O’Connor, founder of Gene Food (<a href="http://mygenefood.com">mygenefood.com</a>), discusses the importance of diet and explains how our genetic composition is literally a road map that takes us to the diet destination our body prefers.


John O’Connor is very passionate about nutrition, genetics, and startups. O’Connor discusses the idea behind his company, Gene Food—which is bio-individuality. As he explains, people are unique individuals and as such respond in their own specific way to different inputs. He talks about the current debate in the public discourse on diets, specifically paleo and vegan diets. O’Connor states that we have genetic differences as individuals, and thus there is a code that we can discover that will inform us about which type of diet will perform best, based on our unique composition. O’Connor discusses his company’s custom algorithm that can parse someone’s genetic data and assign them to one of about 20 different foundational diet categories. As an individual tailors their diet and lifestyle to their specific genetic makeup, they have a greater chance to look their best and perform their best, not to mention feeling better than perhaps they ever have. The Gene Food custom nutrition plan utilizes raw data from popular genetic information providers such as 23andme and Ancestry.com to design a custom nutrition report tailored to one’s particular genetics.


O’Connor discusses genetic variants and how diet plays an important role for everyone, specifically those who have increased risk for certain diseases, such as Alzheimer’s and others. He discusses inflammatory response in regard to diet, and how certain diets affect those who are at increased risk for select diseases and conditions. He details the importance of being cautious about the types of fats that people consume, especially if they are genetically predisposed to have a higher risk of a type of disease. Many of these people should consider Omega 3s and polyunsaturated fats he concludes. 


The diet and nutrition expert provides and overview of SNPs which are single nucleotide polymorphisms, commonly pronounced as ‘snips’ in the scientific community. SNPs are the most typical type of genetic variation in people. Each individual SNP represents a difference in a specific single DNA building block, known as a nucleotide. Further, he delves into the many kinds of diets that they assign to their subscribers, and how their custom report provides a wealth of information on foods to avoid as well as foods to seek out, all based on one’s internal genetics.


O’Connor talks about the vision he has for his company and his future plans to roll out more health coaching, as the appetite for it is great based on the extraordinary volume of questions they receive on their blog daily. And O’Connor discusses physical environments and their impact on how one might react to food, discussing histamine intolerance and more. Interestingly, even one’s selection of their social drink of choice could make a difference based on their histamine intolerance. So whether you order a beer, a gin and tonic, or a glass of red wine, your genetic report can inform you about which one is okay, and which is not. O’Connor’s team seeks to end dietary dysfunction and find ways for every individual to eat better, in line with their genetic makeup, and feel better overall. 

Testing Cutting-Edge Technology in Sleep Medicine, Bringing Relief to Patients—Adam Moseley, Dale Moseley, and Joe Schulz—Delta Waves

Feb 7, 2019 34:19

Description:

Sleep medicine is a rapidly evolving field, and Joe Schulz, Dale Moseley, and Adam Moseley are right in the middle of it, working with cutting-edge technology to bring relief for patients suffering from a variety of sleep disorders. In 2005, Joe Schulz was working as a sleep technologist when he founded Delta Waves, a company that seeks to encourage a collaborative effort between doctors and researchers in the diagnosis and treatment of sleep apnea and 60 other sleep disorders.


Adam Moseley is a registered polysomnographic technologist who manages a portion of the sleep department at Delta Waves, running sleep studies in the lab six nights a week, collecting data from patients for the identification of different sleep disorders, and providing immediate intervention for those with low oxygen levels and apnea. From all of the data and patient feedback they’ve received, the team at Delta Waves has gained some major insights, one of which is that the two most common complaints from users of CPAP machines have to do with fit and comfortability. By working with the top two manufacturers of adaptive servo-ventilation (ASV), CPAP, and BiPAP machines, Delta Waves is able to offer patients access to equipment that’s not even on the market yet, and they’re seeing positive results: happier patients, better compliance.


Tune in for all the details and visit <a href="http://deltawaves.org">deltawaves.org</a> to learn more.

Cross-Country Skiing On a Skateboard—Enrique Cubillo—Innovator of SpikeBoarding and CEO of SUSOIX

Feb 7, 2019 33:51

Description:

Enrique Cubillo is an advocate of something you might see often, but not hear about in these terms: transport sports. He explains that transport sports recreate (like all other sports) but also serve transportation skill sets, like in-line skating, scooters, or cycling. But aside from an educator and advocate of these transport sports, Cubillo is the innovator of a set of movements referred to as “SpikeBoarding.” What’s that, you might ask?


“SpikeBoarding is everything that cross-country skiing has ever been, brought onto a skateboard,” explains Cubillo. But beyond serving as a source of transportation and helping people in field games such as field hockey and football, Cubillo explains that by operating on strength, endurance, and balance, SpikeBoarding can address the increasingly common single sport use issues that are leading to injuries. Cubbilo is also the CEO of SUSOIX, which is a manufacturing company that teaches and produces equipment for SpikeBoarding. To learn more about this sport that’s quickly gaining traction, tune in, visit <a href="http://spikeboarding.com">spikeboarding.com</a>, and check out their YouTube channel for some awesome videos.

An App That Can Help You Achieve Deep, High-Quality Sleep—Daniel Gartenberg, PhD—Sonic Sleep Coach

Feb 6, 2019 34:04

Description:

Many people are unaware of how much their environment can impact their sleep; everything from light and temperature to the sounds in the room while sleeping can mean the difference between waking feeling refreshed and able to function at your best, and waking feeling sluggish, unmotivated, or depressed.


Daniel Gartenberg, PhD was practicing as a psychologist about 10 years ago when he shifted his focus toward wanting to change the structure of healthcare in a way that would address the issues that can arise with the one human behavior practiced more than any other: sleep. In his opinion, improving this behavior even just a little bit could have a massive impact on the health of society as a whole.


So what is he doing to achieve this? Gartenberg is the founder of Sonic Sleep Coach, a software platform that uses the best IoT devices available to manipulate sound, light, and temperature to deliver better results than medication can—and without all of the harmful side effects. In addition, the Sonic Sleep Coach app has the ability to collect an enormous amount of data in just a few nights in order to deliver people with customized recommendations about the root causes of their sleep problems and what they can do to address them. Ultimately, people are provided with personalized cognitive behavioral therapy assessments that go far beyond the treatment of mere symptoms. 


The app is currently available for iOS and will soon be released on Android. Interested in checking it out for yourself? Tune in and visit <a href="http://sonicsleepcoach.com">sonicsleepcoach.com</a> to learn more. 

Aric Prather, PhD—University of California, San Francisco Department of Psychiatry

Feb 6, 2019 30:55

Description:

As a clinical health psychologist and assistant professor at the University of California, San Francisco (UCSF) Department of Psychiatry, Aric Prather, Ph.D. focuses his work on understanding the underlying biological pathways through which sleep, stress, and other health behaviors affect our overall states of health. One of the main ways in which both sleep and stress can affect our health—as many people know—is by contributing to weight gain and obesity, and Dr. Prather works with the UCSF Center for Obesity Assessments, Study, and Treatment to better understand the specific mechanisms at play here.  


He also spends his time in the lab conducting research alongside other scientists to identify markers of cellular aging, better understand the role of senescent cells in aging, study a longevity hormone that seems to be related to inflammation and oxidative damage, and determine how stress and/or lack of sleep can increase susceptibility to infectious disease. Ultimately, the goal is to collect data that might augment our understanding of how sleep, stress, and other behaviors contribute to our health.


Dr. Prather touches on a variety of fascinating topics, including the possible relationship between genetic changes and acute stressors, the potential heritability of stress behaviors, long-term impacts of early life trauma, and the surprising consistency of their findings in sleep research.


Tune in for all the details, learn more about Dr. Prather’s work on the UCSF website, and follow him on Twitter.

Embracing and Finding Strength within the Childhood Cancer Journey—Justin Wilford, PhD—MaxLove Project

Feb 6, 2019 30:06

Description:

In late 2011, Justin Wilford and his wife’s life changed forever in an instant: their son Max was diagnosed at age four with an unclassified brain tumor leading to hydrocephalus and the need for emergency brain surgery, followed by over a month in the hospital, followed by out-patient chemotherapy. “We were shifting between utter despair and asking how we could improve his quality of life right now and for the long-term outcome,” says Wilford. Having recently completed his Ph.D. in Geography, Wilford utilized every connection he had in academia, reaching out to as many researchers and doctors as he could in the hopes of figuring out what he could do to give his son the best chance of high-quality life.  


Throughout the process, Wilford and his wife met tons of parents who were in similar situations with the same concerns, but without the resources that they had. They wanted to provide other families with the resources and education that would allow their kids to thrive as much as possible—and it is from this desire that MaxLove Project was founded.


MaxLove Project is based on seven general actions denoted by the acronym “B.E.S.U.P.E.R.”, each of which is incorporated in their mission—whether in the form of culinary programs in hospitals, fun exercises lead by physical therapists and trainers, or mindfulness and meditation classes for parents. Wilford joins the podcast to discuss each and every one of them, along with details from his personal journey, what they’re working on now, and an update on how Max is doing. 


Tune in and visit maxloveproject.org to get involved.

Scandals & Frauds – Rebecca Jarvis, Chief Business, Technology & Economics Correspondent for ABC News – Analyzing the Newsmakers - Making Sense of Some of the Most Alarming Business Scandals and Frauds of Our Time

Feb 1, 2019 38:39

Description:

Rebecca Jarvis, Chief Business, Technology & Economics Correspondent for ABC News provides interesting details on her long career in journalism and specifically the amazing story of disgraced entrepreneur, Elizabeth Holmes and her company, Theranos.


Jarvis is a seasoned journalist. In addition to her prominent work with ABC News, she serves as host and managing editor of the popular podcast No Limits with Rebecca Jarvis, as well as host and managing editor of Real Biz with Rebecca Jarvis. Her extensive work for ABC News includes critically acclaimed shows such as World News Tonight with David Muir, Nightline, 20/20, This Week with George Stephanopoulos, and Good Morning America. Throughout her impressive career she has regularly interviewed innovators and visionaries such as Warren Buffett; Sheryl Sandberg; Richard Branson; Diane von Furstenberg; and GM’s first woman CEO, Mary Barra, just to name a few. From presidential elections to the Great Recession, the Madoff scandal and the crash of Bear Stearns and Lehman Brothers, if it’s important business news, Jarvis has covered it. 


Jarvis discusses the riveting story of Elizabeth Holmes and Theranos. Jarvis’ work on The Dropout, a documentary podcast by ABC Radio & ABC News Nightline that covers the story of the aforementioned Holmes, has received critical praise. The Dropout explores the ambition and fame that went awry for the world’s youngest self-made woman billionaire. It seeks to unravel the story of Holmes and get to the bottom of how a woman at the top of her game, who was often referred to as ‘the next Steve Jobs,’ could lose everything and face severe criminal charges. Theranos was a health technology corporation that experienced a meteoric rise in the medical technology industry with what was then heralded as breakthrough technology—a means to perform blood tests with extremely smaller amounts of blood than had been historically possible. However, if it sounds too good to be true it often is, as Holmes was later exposed for making false claims about the company and the tech, and was indicted on wire fraud and conspiracy charges. Jarvis explains how she became intrigued by not only the technology Theranos was proposing but also the scores of big-dollar investors who jumped on board early stage to back the so-called groundbreaking technology. Jarvis comments at length about how amazing it is that time after time so many truly smart people can be fooled by swindlers like Bernie Madoff, Elizabeth Holmes, and others like them. She describes it as “affinity fraud” in that people tend to trust those whom their friends and associates have already placed trust in. Jarvis goes on to say that Holmes was truly a brilliant woman to accomplish all that she did in high school, college, and beyond and that everyone who knew her was aware of her incredible aptitude in many areas. Unfortunately, she took a very wrong turn.


Further, Jarvis talks in general about business and investments. She explains that sometimes it is necessary to fight one’s own nature, and she cites examples of how some people have lost greater by quickly pulling their money out of the market when there is a slight shift. The lesson, she states, in terms of business and investment, is to always ask questions and get answers, and those who do often get it right. 

Thomas J. King, Businessman, Author, Founder of Stevia Brands — The Benefits of Going Keto – The Ketogenic Diet, Keto Products, and How We Can Reduce Our Sugar Intake

Feb 1, 2019 31:20

Description:

Thomas J. King, businessman, television producer, filmmaker, and author, delivers an interesting overview of the ketogenic diet, keto products, sugar alternatives, and healthy living. King leads the successful healthy food company known as Icon Foods. Icon Foods supplies the health food industry with various natural alternatives to sugar. Icon Foods will be appearing soon at the Metabolic Health Summit.


King received a BA in environmental studies from Chadwick University and attended graduate school at the University of California, Los Angeles, where he studied law. King founded Stevia Brands as a company that delivers an alternative to the sucrose and high-fructose corn syrup used in so many food products and food preparation. Stevia Brands Inc. is now one of the largest importers, manufacturers and distributors of truly clean-label sweetening systems as well as natural sweeteners. Thom has been passionate about food and nutrition for a long time, and this passion led him to the ketogenic diet, of which he is a devoted fan.


King discusses his background and early years growing up in Colorado and Arizona. He talks in-depth about some of the people who were influential in his journey of discovery, such as Jim May, who was a pioneer in the discovery of herbs and compounds in Central America. This important meeting of two minds was what led to the eventual birth of Stevia, a product that we all know today and see on our grocer’s shelves regularly. Thom King continues with his discussion of all things ‘sweet’ and delves into other sugar alternatives on the market such as aspartame and sucralose, which King carefully points out, do not exist in nature and thus may confuse the body and trigger an insulin response. King talks about their custom sweetening solutions and the various compounds that his company utilizes in their products that manufacturers then use in theirs.


King’s new book, Guy Gone Keto: How to Lose Weight, Feel Great and Achieve Lifelong Fitness is an insightful literary journey into the world of keto. The essential guide and how-to book delivers a wealth of information on the topics of good health through diet, losing weight (and keeping it off), and fat burning. As someone who struggled with weight loss for years, Thom understands the frustration many may have as they try to lose weight unsuccessfully. Guy Gone Keto explains the details of how fat is burned and how a high-fat, low-carb diet can produce amazing results for most people if they stick to it and are dedicated. The book elaborates on diet and nutrition, explains how to understand food labels, and includes many recipes to help people get started on their journey to good health. 


King talks about some of the success stories that people report after having major transformations in health and weight, and how they inspire him to keep moving forward delivering products and information that help people reach their personal goals. Continuing the discussion of his company’s vision, King describes some of the biggest challenges he faces when trying to make certain foods into keto-compliant versions. And he tells the story of his own personal desire to have keto-approved condiments to replace the non keto ones on the market, and how his own taste buds pushed him to create these products that later he found many others wanted as well.


Lastly, King talks about the upcoming Metabolic Health Summit that he is enthused about and the many products and events that will be there for everyone to enjoy and experience in this 4-day immersive health summit.

Wearable Sensors — Carlos Olguin, Co-founder and CEO, LogicInk — Skin Sensors That Deliver Important Information About What’s Going On In Our Bodies, and Around Us

Jan 31, 2019 29:10

Description:

Carlos Olguin, co-founder, and CEO, LogicInk (<a href="http://logicink.com">logicink.com</a>), provides an overview of the current state of wearable sensor technology that can help us to monitor our bodies and protect our health.


Olguin holds an MSc in information networking from Carnegie Mellon. Olguin discusses the range of conditions that we experience in our bodies throughout the day. He explains that wearables tend to be expensive, bulky, with high learning curves, and often require other devices to work with them, in tandem, and thus are not practical. Olguin’s company seeks to change all this, and they have with the launch of their tattoo-style wearables. Their products are placed on the skin and can deliver important information to the wearer about what is going on in their body or even alert them about environmental conditions, from alcohol-intake to hydration levels, and eventually glucose, to environmental contaminants, sun exposure and more.


Specifically, regarding sun exposure, LogicInk can help people to stay within daily recommended UV limits, as well as reveal the irreversible accumulation of UV on your skin. How does it work? The outer circle and bar will turn completely pink when someone reaches their daily UV limit for sensitive skin. And it’s all based on verified data from the World Health Organization. And the inner circle and dot show current UV exposure, in real-time. Olguin talks about the progress of their product development. Many products are currently in process and his team is working to deliver them to the marketplace, but currently they have shipped 25,000 units of their premiere product, LogicInk UV. Other electronic-based products require a smartphone—LogicInk does not. LogicInk has been developed with changing shapes and very bold colors so a user can see their UV status with a quick glance. And if they like, there is an optional mobile app to track UV exposure patterns across extended periods of time.


Olguin details how their sensors work and the data that their products deliver. He talks about the kinds of skin cancer that people develop, and the benefits of controlling your exposure to excessive, harmful sun exposure. He gives an overview of their environmental sensors and explains how they can alert users to potentially harmful pollutants in the environment. And with so much expansion and development, Olguin talks about their partnerships and investors, and his hopes for further product releases in the near future.

Quality Written Content – Tommy Joiner, Founder of Content Pros – Getting More Bang for Your Buck With Higher Quality Content

Jan 31, 2019 24:03

Description:

Tommy Joiner, founder of Content Pros (<a href="http://contentpros.io">contentpros.io</a>) delivers a fascinating overview of content creation for businesses and how quality content is essential for attracting and keeping customers and buyers.


Joiner’s company, Content Pros, produces subscription-based, high quality written content for digital marketing as well as SEO agencies/ B2B software/ service/ and product businesses. As Joiner states, their content brings target buyers to you and engages them at a tremendous cost and time savings for your company.


Joiner talks about the ways they fulfill content needs for their various clients. While many companies do want content, Joiner states that some do not have the hands on deck to produce the content they desire to push to their network, customers, and buyers. Joiner believes that quality content has to begin with high-quality content writers, and as such Content Pros seeks out the absolute best writers in the marketplace. They pay their writers more than the standard, and thus attract better writers because of that. And not only do they provide higher quality, their team turns around content orders significantly faster than most other services in the content space. Customer service matters to Joiner, and as such each of their accounts has a dedicated customer success manager, a specific assigned writer, as well as editor, which clients have access to directly.


Joiner discusses the way they build their base of quality writers and the areas of expertise and specialization their writers inhabit. As he states, their writer pool is so deep and diverse that most any client can benefit from having a writer on board who is a specialist in the subject area, instead of just a general writer as other content provider companies might put on the job. Joiner discusses the unique qualities of their writers and what he and his team look for in a new writer that they are considering. 


The content guru details the various ways businesses can succeed by utilizing Content Pros’ services. Content Pros operates as an extra member of the company’s team, fulfilling their content needs in an efficient manner, and reaching potential customers or clients in an exciting way. Joiner states that many of their clients tend to work with the same writer ongoing, as that writer’s style becomes the central voice for the company’s content. Further, he talks about structure and consistency within the content and the importance of understanding what type of content yields the greatest value or return. He discusses the importance of different strategies and how long form content is often a great way to attract interest. Additionally, Joiner outlines the benefits of updating old content or posts to keep it fresh. And over time your entire content area becomes more valuable as you update.


Finally, Joiner discusses the packages that Content Pros offers for clients. Pricing options and different packages can be viewed online, and Joiner states that they offer a 100% money back guarantee, so there is no risk for anyone interested in giving the service a try. Content Pros will work until the client is truly satisfied, with no questions asked. They guarantee 100% satisfaction with unlimited revisions. And if a client simply is still not satisfied after revisions, then they can receive a full refund. With an offer like that, it seems obvious that every business would want to take a dive into the traffic-generating content space.


Ketone Miracles — Mary T. Newport, MD, Caregiver, Author, Speaker — The Power of Nutrition & Ketones -Treating Disease and Illness Through Supplementation and Diet

Jan 31, 2019 59:38

Description:

Mary T. Newport, MD is a physician, caregiver, author, and international speaker. Her website is packed with useful information and can be viewed at (coconutketones.com). Dr. Newport delivers an insightful overview of nutrition for health. <a href="http://coconutketones.com"></a> Dr. Newport became a ketone enthusiast and nutrition advocate after seeing the benefits in her husband. She provided ketones as alternative fuel for the brain to Steve Newport, her husband, to help with his early-onset Alzheimer’s disease diagnosed at the age of 54. Her books are considered to be invaluable for those who are seeking answers about health. Dr. Newport is the author of Alzheimer's Disease: What If There Was a Cure? The Story of Ketones as well as The Coconut Oil and Low-Carb Solution for Alzheimer's, Parkinson's, and Other Diseases: A Step-by-Step Guide to Using Diet and a High-Energy Food to Protect and Nourish the Brain.


Ketones can be an alternative fuel to sugar for your brain and body. The ketogenic diet and ketone supplements can offer incredible benefits to almost everyone for their general health and may also provide specific help for those who suffer with diabetes, Alzheimer’s, Parkinson’s, ALS, MS, cancer, and epilepsy. The nutrition expert talks about coconut oil, MCT oil, and ketone esters, and their many various benefits for the body. Dr. Newport recounts actual experiences with her husband that showed incredible improvements in his condition after initiating treatment, such as his ability to read again without the words, as he stated, “shaking on the page,” looking pixelated, moving about. 


Dr. Newport talks about how she and her husband transitioned to a more Mediterranean style of diet with lower carbs and more unrefined whole grains. Additionally, she talks about the benefit of Omega 3 and other supplements that could produce real results. She refers to her husband’s recovery as a light that truly came back on in his brain. She discusses her book in detail and how her husband’s story, as recounted by him, made a significant impact in the Alzheimer’s community. She provides extensive details about the ways people can utilize nutrition to improve health, and she provides an overview of her world travels, speaking about disease and treatment via nutritional supplementation and diet. As she states, Alzheimer’s is on the rise all over the world, and even in countries where diets are traditionally very good. She points to sweets and carbs as possibly being the reason for the rise in disease. Additionally, she talks about the toxicity of trans fats that are used again and again for cooking. Ultimately, as she states, the trend is not a good one, as healthy nutrition is less than exemplary in many nations around the world.


Wrapping up her discussion, Dr. Newport discusses some simple things that all of us can do to improve memory and cognition, such as eliminating sugary drinks, reducing starchy foots, and lowering carbs.

Putting Your Data Under the Microscope, Increasing Your Revenue—Carlos Cruz—Clicktool

Jan 29, 2019 23:25

Description:

There’s so much data in today’s world that it can be hard to know which is important and which isn’t, and this is particularly true for those working in the online marketing space. According to Carlos Cruz, CEO of Clicktool, many entrepreneurs in this space are letting important and potentially lucrative data slip through their fingers because they simply don’t have the tools to track it, access it, and make sense of it.


Clicktool launched just three months ago, but it’s already looking like the best data tracking tool on the market. By providing people in the online marketing and ad campaign space with simple, to-the-point, and easy-to-interpret reports on their data, Clicktool users are empowered with the ability to make smarter decisions about how to use it and where to invest their money. “Good data helps you make great decisions about what to do moving forward with any project in your company,” says Cruz, who joins the podcast to discuss all the details of Clicktool and their future plans for the implementation of machine learning algorithms. 


Press play and visit <a href="http://Clicktool.com">Clicktool.com</a> to learn more. 

Incentivizing the Security and Transparency of the Crypto Economy—Grant Blaisdell—Coinfirm and AMLT Network

Jan 29, 2019 31:36

Description:

In the world of blockchain and cryptocurrency, a lot has happened in a short period of time, but one concern has remained paramount for the industry as a whole: security. When an entity encounters ransomware or finds themselves on the receiving end of nefarious or fraudulent actions, where do they submit the data on the associated addresses? What sort of system needs to be in place in order to not only disincentive these events, but incentive entities to provide data which will help them protect themselves, their partners, and the global financial system as a whole? These were the questions that led to the establishment of Coinfirm and the AMLT Network.


“When we created Coinfirm, we wanted to create a bridge between the crypto-blockchain economies… and wanted to change the reality of compliant systems and how AML (anti-money-laundering) works overall—which in the traditional space is ineffective and inefficient,” explains Grant Blaisdell, co-founder of Coinfirm and AMLT Network. One of the main flaws is the inability to detect risks on an individual basis in regions of the world such as Nigeria and India, where the economies have a lot of potential but entrepreneurs are stymied by high-risk labels and the resultant inability to access the global financial system. The team at Coinfirm is working to change this by creating a system that incentivizes entities to report the data associated with both good and nefarious actions. Once Coinfirm receives that data, they implement it quickly in order to alert other exchanges and individuals of risks. So, what’s the incentive? AMLT tokens which can be used for discounted services on the AML platform.


Blaisdell offers a highly informative conversation packed with the latest and most pertinent information in the blockchain and crypto space. Tune in to learn more about Coinfirm’s implementation of the first-ever blockchain lab in Africa, how their approach is different and more likely to succeed than others, the integration of Trudatum with Central Europe’s largest bank, and what’s to come in 2019. 


Learn more by visiting <a href="http://coinfirm.com">coinfirm.com</a>.

Expanding and Enhancing Live-Streaming Video Experiences—John Petrocelli—Bulldog Digital Media

Jan 28, 2019 28:24

Description:

In recent years, increases in bandwidth, the development of multi-camera video technology, the advent of smartphones, and the popularity of social media platforms has led to the hyper-acceleration of the world of live-streaming video. Bulldog Digital Media (DM) is a live-streaming company focused on bringing premium content and best practices to this exciting and expanding market, helping content owners, brands, agencies, platforms, and artists harness the power of live-streaming video in order to deliver the best possible experiences for consumers. With the explosion of social media platforms like Facebook, Twitter, Instagram, Snapchat, and Twitch, there’s been a real interest in shared and participatory experiences—particularly among millennials.


CEO of Bulldog DM, John Petrocelli, and his team are dedicated to increasing consumer engagement and bringing these experiences to life. Among other topics, he joins the podcast to discuss the challenges in keeping consumers engaged for extended periods of time and how to overcome those challenges, the falling prices of high-quality video equipment and how this has impacted the space, and the development of a proprietary tool that’s allowed Bulldog DM to deliver four-camera HD-produced experiences on Instagram.


Tune in for all the details and visit <a href="http://bulldogdm.com">bulldogdm.com</a> for more

Subpar Sleep – Meir Kryger, MD, FRCP(C), Author and Professor of Medicine, Yale School of Medicine – The Many Issues and Conditions of Sleep, Diagnosis and Treatment

Jan 23, 2019 30:56

Description:

Meir Kryger, MD, FRCP(C), author and professor of medicine (pulmonary) and clinical professor of nursing, Yale School of Medicine, delivers a thorough analysis of the current state of sleep medicine and sleep disorders.


Kryger’s book, Principles, and Practice of Sleep Medicine, now on its 6th edition, is considered a must-have guide on sleep medicine, and is basic reading for everyone in the field. The essential read provides an overview of every aspect of sleep disorders, which gives physicians important information to use for their patients who are suffering from sleep-related issues. 


Dr. Kryger discusses his entry into the interesting world of sleep medicine. He recounts the treatment of one of the first patients he diagnosed with a sleep disorder and his shocking revelation that, at the time, hardly anyone knew anything at all about sleep. Over the years his intensive research on sleep has evolved, from his early study of what later became known as ‘sleep apnea,’ which affects approximately five to ten percent of men and up to two to five percent of women, to other sleep-related issues. 


Dr. Kryger discusses sleep apnea in detail and emphasizes the impact that being overweight has on sleep. But he stresses that tonsil size, jaw structure, and many other issues can cause sleep apnea in normal weight people quite often as well. He details the breathing process during sleep and outlines the breath stoppages that occur for those who suffer from this common disorder. 


The sleep doctor details the various treatment devices on the market today, for treating sleep disorders. He discusses CPAP in detail. CPAP stands for Continuous Positive Airway Pressure therapy and it is a common treatment for a type of sleep apnea known as obstructive sleep apnea. A CPAP machine contains a hose and mask, or a nosepiece, and delivers a constant and steady air pressure, which regulates proper breathing. The doctor talks about other medical issues such as hypoventilation, COPD (chronic obstructive pulmonary disorder), and narcolepsy—a chronic sleep disorder that is characterized by intense daytime drowsiness and sometimes even sudden attacks of sleep.


Dr. Kryger’s research has literally covered every area of sleep. He has published over 200 research articles and book chapters. Notably, Dr. Kryger was the first to establish a functional laboratory to study patients suffering from sleep breathing problems in Canada, and first to diagnose and fully report on obstructive sleep apnea in all of North America. Dr. Kryger’s laboratory created awareness for the interaction between heart failure and sleep respiration and the lab published the first systematic study of oxygen in this particular condition. His important and extensive research has received generous funding from various government and industry sources from Canada, France, and the United States. 

Identifying and Changing the Thoughts, Feelings, and Behaviors that Contribute to Insomnia—Alisha L. Brosse—Author of End the Insomnia Struggle

Jan 22, 2019 29:52

Description:

When you think of possible treatments for insomnia, the first thing that comes to your mind probably isn’t cognitive behavioral therapy (CBT), but Alisha Brosse, author of End the Insomnia Struggle, joins the podcast today to discuss why it should be. Simply put, CBT involves the interrelationship between the way we think about things, how we feel about those things, and how we respond behaviorally. And when CBT is applied to sleep disorders, it also involves the physiological contributions and consequences of our thoughts, feelings, and actions.


“We help people change their behaviors and attitudes so they can let their body do what it instinctively needs to do,” explains Brosse. Many people who suffer from insomnia begin to think night after night about the consequences of inadequate sleep, and how it will affect the following day. They’ll also change their behaviors, perhaps by staying in bed for longer (without actually sleeping), consuming more caffeine during the day, or cutting back on social activities at night. In CBT, these behaviors are referred to as compensatory, and are actually counterproductive to sleep.


Brosse offers an eye-opening discussion that touches on a variety of topics, including the methods and strategies used to help people who suffer from different types and stages of insomnia, a number of other conditions and factors that can either trigger a lack of sleep or be the consequence of it, and the common mistake of assuming that mental disorders always precede or are the cause of sleep issues. Tune in for all the details, check out her book on Amazon or Barnes and Noble, and visit her website at <a href="http://bouldercbt.com">bouldercbt.com</a>. 

Encouraging the Movement toward Metabolic Health—Victoria Field—2019 Metabolic Health Summit

Jan 22, 2019 21:51

Description:

Metabolic Health Summit 2019: it’s a four-day experience where you can see 40 of the world’s top physicians, scientists, and researchers come together to present the latest research in metabolic health, share inspirational stories and successes, put on cooking demos, and enjoy overall amazing entertainment while empowering yourself with the knowledge and education to make informed and healthful decisions about your life. This year’s content will not only focus on nutrition and metabolism as key components of human health and longevity, but also how to turn the information into action, implementing it into your daily life.


Returning guest and founder of the Metabolic Health Summit, Victoria Field, offers an exciting glimpse of what to expect this year, and mentions some of the speakers she’s most excited to hear from, including the first psychiatrist out of Harvard who is using keto and low-carb nutrition as an alternative to pharmaceuticals for certain mental illnesses, and a veterinarian who's using metabolic therapies in the treatment of canines with cancer. Slated for January 31st- February 3rd of this year in Long Beach, CA, the third annual Metabolic Health Summit will be a scientific conference unlike any other.

The Skinny on Skincare — Dr. David Heath, Founder and CEO of Cutitronics — Building Technology That Helps Skincare Product Users Maintain Proper Use and See Results

Jan 21, 2019 33:33

Description:

Dr. David Heath, founder, and CEO of Cutitronics (cutitronics.com) provides an overview of the skincare industry and his company’s mission to revolutionize the way we care for our skin.

With a thirst for knowledge, Heath set out on a journey to better understand science and engineering. His long academic career awarded him degrees in physics and engineering. Throughout his Ph.D. and post-doctoral research, Dr. Heath has continually targeted specific areas of interest including transdermal medical technology. Dr. Heath’s research led him to discover that transdermal medical technology could be utilized to solve some of the significant challenges facing the cosmetic skincare industry. His innovation in the area garnered recognition from the Royal Society of Edinburgh, the Royal Academy of Engineering, and the ERA Foundation.



Dr. Heath discusses his extensive background in biomedical engineering and the development of medical devices. He talks about his work that involved research to better understand the dynamic nature of skin, and how it led to his motivation to bring digital technology and engineering together to work with chemistry and formulation to ultimately improve skin and skincare. Dr. Heath explains microdermabrasion and other techniques that are common in the multibillion-dollar skincare industry today. He explains that the dynamic nature of skin needs to be understood in detail in order for products to be successful and that in and of itself is a challenge, as skin is somewhat complex. He discusses fat-soluble and water-soluble solutions, the benefits versus potential issues, as well as how products and technology used on the skin affect the microbiome. It is important to maintain balance he states, and we need to all be conscious of the products we use on our skin. 


The skin expert discusses clinic trials, and how people may not be disciplined enough to use products in a manner such that clinic trial results can be achieved during home use. Dr. Heath discusses how they have achieved a way for their devices to dispense the amount of product that a particular user needs to see progress and eventually—results. By using progress bars or by gamifying it, users may be more motivated to keep working toward their goal. He details other technology aspects of the industry, and as he states, consumer compliance is critical in order to get consumers to use products properly, such that they will see benefits. 


The skincare doctor provides some information on the prevalence of skin specialists and diagnostics in the US versus Europe. He states that their handheld devices help to extend specialized care into the home, to make it easier for individual users to take care of their skin in the proper way, as their specialist would recommend.


The Cutitronics team seeks to continue launching disruptive technology into the skincare market, to help everyone achieve better results in their quest for healthier skin.

Researching Disease — Miroslava Cuperlovic-Culf, Senior Research Officer, National Research Council of Canada — The Important Research of Cellular Metabolism for Understanding Disease and Developing Treatments

Jan 21, 2019 34:06

Description:

Miroslava Cuperlovic-Culf, senior research officer, National Research Council of Canada, delivers a detailed analysis of her intensive research at the cellular level of life sciences.


Cuperlovic-Culf earned her Ph.D. in physical chemistry from UC Santa Barbara and her postdoc in biophysics from the University of British Columbia. Cuperlovic-Culf is extremely interested in the development of applied research collaborations in all the life sciences. She has tremendous experience that has yielded patents and publication of her work in biomarker discovery and (clinical) validation, metabolomics, cheminformatics, as well as bioinformatics.


Cuperlovic-Culf discusses the ways that she and her team use machine learning in their research within the life sciences. Specifically, she details how they collect data and use machine learning to analyze it. She discusses disease development, and the methods they use to dig deeper into this area of research. Their work delves into the metabolic analysis of cell cultures, and has many potential applications and advantages to the currently used methods for cell line testing. Research shows that metabolite concentrations represent important, sensitive markers of both genomic and phenotypic changes. Cuperlovic-Culf discusses their research of potentially deadly brain tumors. As cancer is known to have an appetite for glucose, and other specific energy sources, Cuperlovic-Culf studies metabolism within cells to better understand genetic changes. 


The biophysics expert gives an overview of the various metabolic signatures of cells. Specifically, cancer cells have several detailed metabolic features, which have been explored for targeted therapies. She talks about the unique characteristics of cancer cells, such as their lactic acid content, etc. which is not typically seen in normal cells. And by utilizing simulations, Cuperlovic-Culf and her team can get a better idea of where the cell is going so to speak, to learn more about its development in hopes to find new ways to treat disease. The PhD discusses other diseases that have important metabolic components as well, such as Alzheimer’s disease, and type 3 diabetes, etc. Dr. Cuperlovic-Culf states that once we understand the relationships we can develop better, more-focused drugs for treatment.


Cuperlovic-Culf speaks about the incredible wealth of data that is unfortunately still missing, and as such much more research needs to be done. She discusses microorganisms in soil and how they interact, in regard to biodegradability. Cuperlovic-Culf states that she wants to further her research, to look at metabolites beyond metabolism, how cellular processes are being inhibited, why, and what it all means for disease development, and hopefully drug development as well. 

Data Discoveries — Ed Lorenzini, President and CEO, and Scott Chase, CTO, of Analyze — The Importance of Analyzing Customer Data To Drive Sales and Understand Demographics

Jan 21, 2019 34:39

Description:

Ed Lorenzini, president, and CEO, and Scott Chase, CTO, of Analyze (<a href="http://analyzecorp.com">analyzecorp.com</a>), deliver a useful overview of data analytics and how it can help every business target new potential customers, as well as retain existing customers. 


Ed Lorenzini has over 30 years combined military and commercial experience and is a retired Air Force officer. He is a proven leader as evidenced by his long, successful career. Lorenzini’s interests are in behavioral analytics, intelligence fusion, and intent recognition. Scott Chase, CTO, has spent his career focused on distributed computing and large scale data analytics. Chase has a particular interest in federal-sector cybersecurity analytics and is an innovator in the space. Together, Lorenzini and Chase have built their business, Analyze, into a powerful data analytics company.


Lorenzini talks about Analyze’s specialization in predictive analytics, especially in the area of consumer behavior. He explains how they use AI in the development of the front end of their platform, Analyze Clients. Analyze Clients produces essential consumer insights with only names and addresses. By bringing together millions of records into a huge database of cloud-based knowledge, the platform allows users to enter a customer's first and last name, address, and then zip code, and begin to analyze it all, in order to build a detailed analytical report on customers. He discusses how advertising companies are utilizing their service for direct mail, calls, and more. As Lorenzini states, they have invented a way to develop an automated, custom algorithm on the fly. 


Chase talks about the many variables that exist within available data on consumer households, and how over 200 of the 380 variables are consumer lifestyle variables, for example: owns a dog, subscribes to magazines, enjoys boating, etc. Chase explains that they can use the available data to build a model based on specific lifestyle variables that will allow businesses to understand whom their product will resonate with.


Lorenzini discusses consumer buying patterns and the various demographics that exist. He explains that the data is good at helping businesses understand their consumer base and to make assessments about growth and marketing. He explains the changes that have taken place in ecommerce and the digital economy overall. The founders of Analyze cite examples of some success stories from users of their platform, some that have seen as much as 300% revenue growth based on customer insights they began receiving via the platform.


Data analytics combined with consumer behavior can bring dramatic major benefits to companies seeking to expand, and data insights can help entrepreneurs and business owners develop successful strategies for growth.

Whole Genome Sequencing: Unlocking the Power of the Data in Your Genes, At a Price You Can Afford—Rodrigo Martinez—Veritas Genetics

Jan 21, 2019 42:36

Description:

An unbelievable amount of useful data is stored in our genes—data which could help us make better decisions about our health and guide us toward lifestyle changes which could decrease our chances of developing certain diseases. With a price tag between $10,000 and $30,000, however, the process required to generate this data, which is referred to as genomic sequencing, simply isn’t a feasible option for most people.


Just a few years ago, the team at Veritas Genetics set out to change this, believing that anyone should be able to obtain this genetic info for under $1,000. In contrast to the technology used by companies like Ancestry and 23andMe, Veritas Genetics’ technology sequences the entire genome—all six billion bases. “We generate more data in a week than all of the data 23andMe has generated in the last 11 years,” says Rodrigo Martinez, Chief Marketing Officer at Veritas Genetics. He explains that one of the primary benefits of this extra data is that it confers the ability to identify completely new information within the genome, rather than simply ask questions to which we already have the answers.  


A report form Veritas Genetics can inform you about your risk or predisposition to the development of certain diseases, whether or not you are a carrier of certain conditions which could be inherited by your children, and what types of substances you may have sensitivities to. Once your genome has been sequenced by the team at Veritas, you can refer back to all of the data at any point in the future, which may become particularly useful in light of findings from new research.  


Interested in getting started today? Tune in and visit<a href="http://veritasgenetics.com"> veritasgenetics.com </a>to learn how.

Mission to Mercury — Elsa Montagnon, BepiColombo Spacecraft Operations Manager — Discoveries in Space, Answering Questions About Mercury’s Chemical Composition and Magnetosphere

Jan 18, 2019 33:45

Description:

Elsa Montagnon, BepiColombo Spacecraft Operations Manager, discusses the latest mission to Mercury, its complexity, and what scientists hope to discover.


Elsa Montagnon is an interplanetary spacecraft operations expert. She earned her engineering degrees from the Ecole Centrale Paris and Technical University of Munich. Montagnon joined the European Space Agency (ESA) in 1999. Before her work as the BepiColombo spacecraft operations manager, Montagnon was the flight operations system engineer on ESA’s groundbreaking Rosetta mission. The European Space Agency (ESA) is Europe's premier, advanced agency that serves as the entrée to space. The ESA formats and oversees the development of Europe's space capability to track progress and make sure that the investment in space is properly benefitting the people of Europe as well as the world community.


Montagnon discusses ESA’s collaboration with a partner Japanese space agency, JAXA, the Japan Aerospace Exploration Agency. She gives an overview of the BepiColombo’s mission: to explore planet Mercury. She states that Mercury was visited twice before by man-made machines, missions that introduced many questions for researchers as would be expected. She details the importance of putting satellites into different orbits to maximize their findings. Their mission intends to launch a lower orbit survey of the chemical composition of Mercury’s surface, etc., with JAXA’s higher orbit survey satellite that will analyze the magnetosphere and other important issues. A magnetosphere is a region of space that surrounds an astronomical object in which various charged particles are manipulated or impacted by that object's overall magnetic field.


She explains some of the difficulties with a mission to Mercury, due to its close proximity to the sun and the complex trajectory needed to make the journey there. She describes the year-by-year trajectory that must be made in order to approach Mercury, specifically discussing energy and orbit. Survival itself is a challenge in such a high-temperature environment. Near Mercury, the energy from the sun is approximately ten times that of what we experience on Earth. As such, much research and effort goes into coatings and thermal blankets that are absolutely necessary to protect any craft that is approaching Mercury due to the excessive temperature.


The space-engineering expert discusses some of the extra advantages of a Mercury mission, such as the ability to study solar flares and gather new information about the sun. Montagnon explains that the latest mission has literally just begun and that the Mercury arrival will not happen until 2025. She discusses the technical aspects of some of the instruments that will be utilized during the mission, and how they track the mission and the data. Montagnon states that there is a full laboratory on board that allows for exploration and discovery, as scientists seek to take full advantage of every aspect of the mission from beginning to end, from capturing never-before seen views of Venus and other important mission activities. 

Informing Forms — Cedric Savarese, Founder and CEO of FormAssembly — The Revolutionary Platform That Assists With Data Collection and Form Management

Jan 18, 2019 22:18

Description:

Cedric Savarese, founder and CEO of FormAssembly (<a href="http://formassembly.com">formassembly.com</a>), delivers an overview of his company’s platform and how it is revolutionizing the way we use data and manage forms in an ever-increasing digital world.


Savarese’s company, FormAssembly, is a prominent provider of data collection and management solutions. Savarese oversees the company’s direction and overall growth. Savarese is a skilled business entrepreneur with a passion for technology and innovation. He earned a master’s in computer science from the prestigious Université Paris Descartes. 


Savarese discusses the premise of FormAssembly as a platform that enables users to collect data via online forms and surveys for business improvement and efficiency; but Savarese stresses they also have a primary goal of helping users to be responsible stewards of this personal data. He gives an overview of the data that is available and collected online and how it is compiled. From surveys to online competitions to college applications, there is a wealth of data online, and as our society becomes more and more dependent on devices, more data will be coming, with a large percentage of it available for collection.


FormAssembly helps customers streamline, change or improve processes across a variety of departments, groups, and organizations. And their streamlined visual editing and publishing simplifies the creation and management of complex forms. The platform features forms that utilize conditional logic, calculated fields, save functions, and much more, to help business people create successful online forms. The FormAssembly advantage enables users to create and integrate, with a full spectrum of forms for sales, payment collection, authorizations, and beyond—all available through a complete self-service platform. Savarese discusses privacy issues, confidentiality, and other standards that are regulated when sensitive data is handled. As he states, compliance and regulation are key issues in the field. 


Savarese details intake processes and database issues that are part of their industry. Ultimately, efficiency is paramount and Savarese is convinced that the FormAssembly platform can provide easy convenience to individuals and businesses everywhere. Additionally, he discusses the many use cases for their platform, from the small community theater that needs help with their form to collect donations and sell tickets, to Fortune 500 companies with immense funding behind them that prefer to use the FormAssembly platform to save time, and money. Finally, Savarese delivers an overview of the user experience and the type of users that come to their platform, general best practices, their platform’s built-in filters, and some interesting past experiences he and others have been through in regard to data and form usage. <span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span>

Creating On-Demand Human Tissues Using 3D Printing Technology—Tamer Mohamed—Aspect Biosystems

Jan 18, 2019 27:27

Description:

One of the major roadblocks to human tissue engineering has been the ability to vascularize tissue, confining the majority of tissue creation to that which doesn’t have a strong blood supply in the body. The team at Aspect Biosystems, however, is working to change this by developing innovative strategies and opening their platform to collaborative efforts with academic partners around the world. For instance, they’ve partnered with UCLA in the development of new vascular technology as well as researchers around the globe who are working on the creation of kidney and skin tissues.


Tame Mohamed is the CEO of Aspect Biosystems and joins the conversation today to discuss all of this and more, including their muscle portfolio composed of intestinal, cardiac, and smooth muscle tissue, liver drug testing platform, and pancreatic tissue program for the treatment of type 1 diabetes. He also explains the ins and out of the technology behind their work, and what to look forward to in the near future.


Press play for the full conversation and learn more by visiting <a href="http://aspectbiosystems.com">aspectbiosystems.com</a>.

Globally Revamping Outdated 911 Communication Systems and Saving Lives—Michael Martin—RapidSOS

Jan 18, 2019 21:57

Description:

The FCC estimates that in 2014, over 10,000 lives could have been saved if only there had been a way for 911 telecommunicators to identify the specific location of 911 callers. It may come as a surprise to many that the technology currently used by 911 systems dates back to the 1960s, and is, therefore, unable to accommodate lifesaving data, such as the location of a caller, the severity of a car crash, or the number of individuals who may be trapped in a burning building. 


Considering that over 650,000 911 calls are made across the US every day—many of which are being made by callers who are experiencing the worst moments of their lives—RapidSOS, an advanced emergency technology company, has asked the following question: how do we upgrade these outdated analog voice systems to rich data networks that don’t just overload the system with info that isn’t ultimately lifesaving? They’ve spent the past four years holding various focus groups with hundreds of 911 centers across the country and partnering with major tech companies in order to provide this lifesaving data during emergencies.


RapidSOS now manages 60 percent of US 911 traffic and provides data to over 2,200 different public safety agencies in major US cities, and have seen response times improve by anywhere from 30 seconds to seven minutes; when even a single second can be the difference between life and death, this technology is rightly considered lifesaving.


Michael Martin, founder of RapidSOS, joins the podcast to discuss the implementation of this new technology and their plans for international expansion. Tune in for all the details and visit <a href="http://rapidsos.com">rapidsos.com </a>for more. 

Living Longer?—Dr. Brandon Milholland, Albert Einstein College of Medicine, Department of Genetics — The Study of Aging, Why we Age, and What the Future Holds

Jan 16, 2019 29:53

Description:

Dr. Brandon Milholland, Albert Einstein College of Medicine, Department of Genetics, delivers a thorough overview of the aging process, why we age, and how lifespan has been viewed historically.


Dr. Brandon Milholland earned his Ph.D. in genetics at the Albert Einstein College of Medicine, one of the nation's most respected centers for research, medical education, and clinical investigation. During his time there he collaborated with other associates from two different teams to research the specific biology of aging. Dr. Milholland has particular expertise in genomics, bioinformatics, and big data. He has published seven papers in peer-reviewed journals, and there are, upcoming, an additional six manuscripts currently under review or already in press. Dr. Milholland received his BA in natural sciences from the prestigious University of Cambridge.


Dr. Milholland discusses his interest in aging, and his transition into the private sector, consulting with pharmaceutical companies. His passion for studies on aging has led him to write on the subject and continue his research. He talks about the lifespan and life expectancy of past generations and cultures, and the differences between the two in how people interpret them. He details how infant mortality rates have affected overall historical records, and discusses how famine and epidemics have impacted past generations and cultures, in terms of lifespan and aging. Dr. Milholland discusses the possibilities of age anomalies in which people outlive the typical age of expected life and historical records that list extremes.


The genetics expert outlines some of the reasons why life expectancies have increased. He discusses theories as to why age plateaus. As he explains, one reason for possible decreases in life extension is that as we age many biological systems may be beginning to fail, but medical treatment often focuses on one major issue alone, not the combination of potential problems. Dr. Milholland discusses aging at the cellular level, and how that impacts the body. He talks specifically about somatic mutation, which is genetic alteration acquired by a particular cell that can then be passed to the descendants of the mutated cell through the course of cell division.


Dr. Milholland specifically delves into the subject of telomeres. Telomeres become shorter each time a cell divides, and when they get too short, that cell can no longer divide thus it becomes inactive or dies. And unfortunately, this process can be associated with many health issues from aging, to cancer, and potentially poses a higher risk of death. 


Dr. Milholland delivers information on his research, and other studies, regarding life expectancy, and whether life span is improving or not. As he states, there are many theories and opinions on the matters of aging, and more research is needed. 

Quantum Queries — Dr. Florian Neukart, Principle Scientist at Volkswagen — Quantum Computing for Research and Simulation, the Pathway to Understanding Materials and Building Better Products

Jan 16, 2019 30:14

Description:

Dr. Florian Neukart, principle scientist at Volkswagen, delivers a comprehensive analysis of quantum computing and simulation utilized for research.


As principal scientist at Volkswagen Group, Dr. Neukart, focuses on intensive research in the fields of quantum computing, quantum machine learning, artificial intelligence, as well as materials science. He is a skilled computer scientist, mathematician, and noted scientific author. His particular study in the area of reverse-engineering the mind by systematically replacing the biological brain with manufactured components, such as quantum nanobots, electrodes, etc. has drawn a lot of interest in the scientific community. 


Dr. Neukart discusses quantum systems and their extensive research utilizing quantum systems for simulation. By simulating molecules and atoms, Dr. Neukart hopes to gain a better understanding of materials’ properties, which could prove very useful for battery materials, regarding cathode and anode. Traditional, non-quantum, simulations leave a lot to be desired, and Dr. Neukart is excited about the accuracy in simulation that can be provided via quantum computers. He details the specifics of algorithms and artificial neural networks in relation to quantum computers with the goal of developing algorithms that are more accurate, and learn faster.


The quantum computing scientist details the movement of specific atoms and electrons, and the process during simulation of working with nuclei to better understand the energy surface of the molecule, to learn more about materials’ properties. Dr. Neukart explains how they use machine learning in their study, and the specifics of training models with quantum chips, to eventually be used in products. Dr. Neukart outlines the types of quantum computers they use in their research and how they work, as well as the potential difficulties each may present. 


Dr. Neukart discusses the third area of interest in their research, beyond materials simulation and machine learning, and that is optimization. He discusses optimization in terms of traffic mobility, citing specifics with transportation services such as taxis, subway, buses, etc. He explains how optimization models can reduce wait times for passengers and increase productivity and efficiency. And this is an area where quantum computing can truly accelerate innovation.


Dr. Neukart earned his Ph.D. in quantum computing and artificial intelligence from the Transilvania University of Brasov, and a master's degree in information technology from the CAMPUS 02 University of Applied Sciences in Graz. Additionally, Neukart holds a master's degree in computer science from the Joanneum University of Applied Sciences in Kapfenbergn. 

Creation Collective — Chris J. Davis, Founder of Filmio — Using Technology to Bring Content Creators New Ways to Break Through the Hollywood Wall

Jan 16, 2019 24:43

Description:

Chris J. Davis, a founder of Filmio (<a href="http://film.io">film.io</a>), discusses his company’s innovative platform that allows content creators to come together with fans and investors to build creative projects that are truly outstanding.

Davis’s company, Filmio, brings creators and fans together in a new and innovative manner to build a space where everyone participates, anyone can create—and all share in the benefits. Filmio seeks to end the monopoly and release the grip that Hollywood has long held on the industry, a grip that keeps most people out and only granting access to the few. As studios have become more and more beholden to their big corporate owners they have distanced themselves from their real audience, the fans, and consumers who view and buy the content. Hollywood continues to make sequel after sequel, refusing to bring new fresh ideas in, but instead simply choosing to remake the same concepts with bigger visual effects that just drive up the costs. Davis believes the time has come to make a paradigm shift, to find a new direction toward better creative built on fresh ideas.


Davis talks about Filmio as a decentralized ecosystem that facilitates the funding, creation, and distribution of film, TV, and VR projects. He gives us an overview of his background as a classically trained artist and how he organically took steps toward his company’s birth. With a keen interest in the blockchain, Davis wanted to find a way to use technology to assist other artists to create and launch projects of their own, in their own way. Davis outlines the early days of Filmio and how it came to be the company that it is today. He talks about the many stories they heard of creators being frustrated with the Hollywood system, and their desire to find a way to circumvent the road blocks. With Filmio, fans, creators, and investors can come together to build success and launch great new ideas. He talks about the advantage of having ideas vetted by the crowd before money is spent. And the beauty of this is that ideas get support early on and those supporters stay with the project all the way through funding and into the launch.


Davis discusses the need for content, with new companies popping up all the time to grab a piece of the lucrative streaming content space. Filmio can provide the technology and support to get content creators up and running. Davis explains the vetting process that allows users on their platform to evaluate and vote a project forward to the next level for development or consideration, etc. When a project hits a certain threshold, tokens are used to vote projects forward. And even when projects move into production, creators can come back to the platform and continually update the supporters with director interviews, location photos, or more, which further engages their original supporters.


Davis talks in-depth about the tokens and their platform’s ecosystem, how it works, and what are the benefits to fans and creators. Additionally, he discusses his upcoming event at Sundance and his excitement about talking to filmmakers there, to create a larger community on their platform where everyone can thrive.

Helping You Achieve a State of Ketosis in a Day, and Maintain it Continuously—Gary Millet—Kegenix

Jan 15, 2019 34:39

Description:

Have you been interested in trying a keto diet, but had trouble getting going and sticking with the strict rules? Or maybe you’re just worried about the infamous “keto flu.” Gary Millet, founder of Kegenix, joins the podcast to discuss a way around these challenges: by consuming exogenous ketones in liquid form and simply reducing your carb intake, you can enter a state of ketosis within a matter of an hour, making the path forward much easier.


The team at Kegenix has combined MCT oil and ketone salts into a substance that not only delivers exogenous ketones but also stimulates your body’s own ability to produce ketones—extending the state of ketosis far beyond what you’d get by just taking ketone salts. They’ve also created the first ketone meal replacement that not only contains all of the macro-nutrients and vitamins that a keto meal would have, but can be made into pancakes, waffles, biscuits, and more. In the works are products designed to specifically address different goals, such as weight loss or increased and sustained energy.


Millet touches on a range of interesting topics, including the important difference between ketone esters and ketone salts, what’s really happening in the body when people experience the “keto flu” and why exogenous ketones can help you avoid it, and what happens when the body uses ketones as fuel versus glucose as fuel.


Tune in for all the details and check out <a href="http://realketones.com">realketones.com</a> for more info.

A Pediatrician’s Advice on Parenting and Caregiving—Laura Jana, MD—Author of The Toddler Brain

Jan 15, 2019 29:50

Description:

As a pediatrician, spokesperson for the American Academy of Pediatrics, and author of The Toddler Brain: Nurture the Skills Today that Will Shape Your Child’s Tomorrow, Dr. Laura Jana is dedicated to one thing in particular: helping anyone who takes care of children figure out how best to do exactly that. Much like her book, the conversation on today’s podcast touches on a range of topics, including how to help children who have difficulty falling asleep, the importance of establishing nighttime routines that incorporate habits of hygiene, how and why the use of technology affects the sleep cycle, when breastfeeding becomes more of a comfort for a child than a nutritional necessity, and the most common mistakes she sees parents make that could be having a harmful effect on their children.  


Tune in for the full discussion and check out the following resources for more information:


<a href="http://Healthychildren.org">Healthychildren.org</a>


<a href="http://Kidshealth.org">Kidshealth.org</a>


<a href="http://Drlaurajana.com">Drlaurajana.com</a>

Driving Insights and Understanding in the Health and Wellness Sector—Eric Steckelman—Evoke Giant

Jan 15, 2019 27:48

Description:

Eric Steckelman is the Chief Growth Officer at Evoke Giant, a healthcare-oriented marketing organization that provides a range of services for enterprise-wide and emerging or startup clients in the health and wellness sector. Whether they’re helping their clients establish commercial objectives, refining their strategies, helping them connect with customers, educating consumers, customers, and providers, or building brand equity and loyalty, the team at Evoke Giant has one ultimate goal in mind: improving patient care.  


Just a couple of years ago, they partnered with the Cancer Education and Research Institute in New York to increase engagement and educate people on cancer immunotherapy. Featuring 30 stories in 30 days, the campaign shed light on the day-to-day experience of cancer immunotherapy from the perspective of providers, patients, and nurses, garnering a huge social media presence.


Evoke Giant is always looking for new opportunities to engage with the healthcare space, so tune in and visit <a href="http://www.giantagenecy.com">www.giantagenecy.com</a> to reach out with questions or ideas and learn more.

Early Detection of Online Fraud Using Unsupervised Machine Learning—Fang Yu—DataVisor

Jan 15, 2019 26:13

Description:

“Existing solutions like supervised machine learning are very reactive to what the attacker is currently doing, so there’s always a cat and mouse game; the unsupervised machine learning that we are building….doesn’t have existing assumptions of what the fraud looks like, and that itself is actually more robust in terms of detection,” says Fang Yu, CTO and co-founder of DataVisor, a company whose mission is to protect large social and financial institutions from the increasing number of sophisticated cyber-attacks.


When the nature of cyber-attacks can literally change on an hourly basis, the technology which relies upon the characteristics of past fraudulent behavior is insufficient. DataVisor’s technology mitigates this problem by reviewing billions of accounts and identifying patterns of fraudulent behavior.


Yu offers a detailed and informative conversation about DataVisor’s services, which are currently protecting over four billion user accounts globally. She also discusses the advanced techniques used by fraudsters, the importance of early fraud detection, and an upcoming enterprise version of their technology which will allow clients to adjust the models themselves and have more leverage over the algorithms.


Tune in, learn more by visiting <a href="http://datavisor.com">datavisor.com</a>, and email your questions to info@datavisors.com.

Subconscious Connections — Ron Spence, MBA, Noted Research Scientist, and Barbara Turner, Celebrated Holistic Health Coach — Unlocking the Immense Power of the Subconscious Mind, Connecting to Incredible Energy Sources, and Improving Our Lives

Jan 14, 2019 36:29

Description:

Ron Spence, MBA, noted research scientist, and Barbara Turner, celebrated holistic health coach and author, discuss the amazing quantum energy mobile app that is impacting lives and creating a swirl of excitement due to its incredible potential.


Turner discusses her broad background in nutrition and health, including her early writing of e-books that dealt with health issues that her personal family members or friends had experienced. Upon discovering a particular email that gave an overview of an energy biofeedback app, she became intrigued to dig deeper into the nexus of health, and app technology. She outlines the Limbic Arc, touted as one of “the world's first quantum-energy wellness products managed with the click of an app.” 


Turner gives an overview of how users subscribe and access the Limbic Arc that gives them access to 150 unique, quantum-energy wellness products, including valuable training from leaders within the Limbic Arc system. The 15-year-old parent company that is the source of origin of Limbic Arc works with literally thousands of physicians and healthcare professionals around the world and seeks to take this groundbreaking new technology to the public for the first time ever.


Spence, who is a master affiliate at Limbic Arc, elaborates on how their technology offering is centered on quantum theory. He recounts some previous remarks by Tesla that speak about a non-physical phenomenon, and underscore the value of Limbic Arc. Spence explains the origination of Limbic Arc by Dr. Vaughn Cook and his early experiences with the platform. He talks about the ear-ringing (tinnitus) problem that he has had for many years, and how the Limbic Arc platform helped him to access energy that eliminated the problem almost immediately. Spence details the biochemical exchange and how information energy exists at the subatomic level. He gives an analysis of his theory about cellular receptors as they relate to disease and illness, and explains the many problems with blockages within the body, sometimes brought on by toxins and other agents that block micronutrients. 


The Limbic Arc has two major parts: a library of valuable information fields that exist in the internet cloud—logarithmic expressions assigned a link with items in the physical world as done by a specialized, proprietary system; and the other part is the app in which users can access and then manage their unique library of Limbic Arc products, called InfoBoosts.


The energy expert, Spence, details how the quantum field works, and the specifics of the limbic system. He states that many of our problems are related to a deficiency in something. He details the importance of breaking blockages and how the app can immediately connect users to energy that can sometimes provide dramatic changes in their lives. Ultimately, Spence states, there are many things that live in our subconscious mind that can be very beneficial to our lives and well-being if we learn how to harvest them. 


Sleep is Serious! — Azizi A. Seixas, PhD, Assistant Professor at NYU School of Medicine — The Power of Sleep and How It Affects Our Health In More Ways Than You Might Expect

Jan 14, 2019 40:55

Description:

Azizi A. Seixas, Ph.D., assistant professor at NYU School of Medicine, in the Department of Population Health and the Center for Healthful Behavior Change, provides an interesting overview of the power of sleep, and the problems we could face when sleep is low quality or we simply don’t get enough.


Dr. Seixas has devoted his career to understanding and addressing the sociocultural and environmental determinants of chronic diseases. Dr. Seixas received an MA from Fordham University and was an advanced doctoral candidate in clinical psychology there. Additionally he received an MS in clinical psychology from The University of Dallas, and a BA​ ​in philosophy and premed studies from College of the Holy Cross.


Dr. Seixas discusses the four behaviors that he considers the pillars of health: physical activity, diet, stress management, and sleep. He states that of the four, sleep has been shown to be implicated in cardiovascular disease, metabolic health conditions, brain health, daily function, and overall quality of life. 


Dr. Seixas’ research focuses on three areas: multilevel determinants of sleep and cardiovascular disease disparities; the long-term health results of cardiovascular disease (CVD) disparities; and developing adaptive, group-tailored, specific and personalized behavior modification interventions, incorporating machine learning analytical tools, to improve overall health and general well being. Dr. Seixas addresses the important sociocultural and environmental determinants of various chronic diseases and behaviors, that often prevent access to basic care in certain disadvantaged communities that are burdened by adverse cardiovascular outcomes in a disproportionate manner. Dr. Seixas‘ work looks at the barriers that hinder diagnosis and treatment of sleep disorders within racial/ethnic minorities and seeks to evaluate the efficacy of behavioral models targeted at improving a commitment to sleep and CVD recommended types of therapies.


Dr. Seixas talks about the ways they reach out to the community, by literally going to retail community shops, such as barbershops and hair salons, to talk to people and work with them. He discusses the sleep education and social support that they offer to at-risk individuals. By introducing a home-based sleep study, and allowing people to avoid going to a clinic for the study they have found a way to offer more significant help to communities, targeting at-risk individuals, testing them, and helping put them on a path toward better health. 


Dr. Seixas was awarded a National Heart, Lung, and Blood Institute (NHLBI) career award to research as to whether inadequate sleep and/or obesity could possibly explain a notable proportion of CVD risk disparity between blacks and whites, through secondary data analysis of the Sleep Heart Health Study.


Dr. Seixas details how simply getting more quality sleep can affect so many areas in our lives, from sex drive to mood, functioning to mental clarity, and so many other serious health issues.


In addition to his work that focuses on population health insights, he is also working on developing precise and personalized behavioral medicine solutions that use artificial intelligence to optimize behavior change and adherence to pro-health behaviors.


Selecting Service – Shivam Bhalla, CEO, and Amedeo Lattari, COO, of Troolr – Connecting Local Service Providers with Those Who Need Them Via Troolr.com

Jan 11, 2019 16:25

Description:

Shivam Bhalla, CEO, and Amedeo Lattari, COO, of Troolr (<a href="http://troolr.com">troolr.com</a>), provide an overview of their new platform that is helping users and service providers connect to get jobs done.


The Troolr founders discuss their vision for making every task efficient and easy, no matter where you are or what you need to get done. Troolr delivers convenience and efficiency. With Troolr, users can easily find reliable local professionals and compare them based on reviews and overall experience. And Troolr makes it simple to communicate directly with the professional you need, without a laundry list of-of questions. You find, connect, and then meet up with the professional of your choosing and get your job completed.


The CEO and COO talk about their platform and the services that many of their providers deliver. Troolr is open to most types of services, in a peer-to-peer based platform, from blue collar to white collar services. Essentially, if there is a demand, Troolr seeks to provide for that by bringing many quality service providers into their extensive network. They talk about the ways in which prospective users can review potential candidates for the job—from reviewing their work history, educational background, social media, reviews, etc., and of course, there’s a photo of the service provider so you know who you’re dealing with. And with thousands upon thousands of businesses already inhabiting their great new platform, information is valuable to help users select the perfect person or team for the job.


Bhalla and Lattari explain the volume of data that they gather that helps users to understand which service providers are being chosen. They state that the local services industry is part of a $400 billion dollar market, and yet it is completely fragmented. And while the market already does have several viable gig-oriented platforms, such as the well known, Angie’s List, Bhalla and Lattari have found through their extensive prelaunch research that there is still plenty of room for newer platforms like Troolr to thrive in the market. 


The founders detail the two major types of users that come to their platform seeking service providers. First, there is the browser, a user who likes to browse the providers online, find who they are seeking, and connect directly. The other type of user prefers to create a call to action, to post their job and have service providers reach out to them. They talk about the detailed profiles that service providers can post on Troolr, and how that offers more value to the user in a qualitative manner. And as they gather more data, eventually they will be making recommendations on their platform about industry standard rates, which will help to ensure that service providers are paid a respectable industry standard rate for their skill and experience.

Bhalla and Lattari discuss their growth plans for the future. They expect to soon release an on-demand system. For example, if you need someone immediately, for plumbing or other need, the platform will provide information on those who are available right now, not tomorrow. Because when you need it now, you need it now. 

If You Build It, They Won’t Necessarily Come – Alberto Savoia, Innovation Expert and Author of The Right It – Getting Serious About Your Ideas and Mapping a Route for Success, Before You Invest

Jan 11, 2019 35:59

Description:

Alberto Savoia, innovation expert, disrupter, and author of, The Right It: Why So Many Ideas Fail, and How to Make Yours Succeed, delivers a lively analysis of the many ways businesses fail, and succeed. 


Savoia is a seasoned tech expert and business consultant who is in high demand at conferences and events. He is a lecturer and innovation consultant at Stanford University and was a key player at Google in the highly sought-after position of innovation agitator. During Savoia’s early career as an engineer and eventually as an engineering executive and CTO he worked for innovation giants such as Sun Microsystems, SunLabs, and Google. Joining Sun Microsystems and Google as well back when they were just start-ups, Savoia’s knowledge and leadership was instrumental in both companies’ steady climb to success. Perhaps it can be said that Savoia’s biggest asset is his ability to help businesses stimulate and foster groundbreaking innovation that yields high-impact product development. 


Savoia talks about his background, starting with early success in the video game space that led to his tenure at Sun Microsystems and eventually Google. He discusses his start-ups and some of his successes and failures. And it was his first failure that inspired him to eventually write his popular business book, The Right It. After suffering a failed start-up Savoia returned to Google, but was still motivated to dig deeper, to help others understand their businesses and succeed in the market. Savoia details how he studied failure, talking to anyone and everyone who would discuss their business failures. From hard data to personal interviews, he amassed a wealth of information that led him to some clear observations about business success and failure. One primary point Savoia nailed down was that most business failures are not because of problems with personnel or execution, but because the company has launched the wrong product. It’s simply the wrong idea. Savoia states that you want to be sure you are building the right it, before you build it right. Savoia gives a detailed analysis of how company owners and entrepreneurs can find their way in a crowded marketplace, and get an understanding of how their product might fair in the market—in the future—before they get there in terms of development and manufacturing. Savoia cites multiple examples of companies’ successes and failures. He outlines the concept of pretotyping, which is ultra-rapid prototyping, essentially a way of envisioning your product before it is developed and built. 


The technology expert provides examples of the many ways that companies can collect data. He delivers an interesting overview of his theories through an example of McDonalds, if they were to introduce a new product, such as spaghetti. He explains that a good way for McDonalds to pretotype is to simply put it on the menu, before it exists. When customers order it, they get a free lunch—no spaghetti, but everyone wins. McDonalds collects valuable data up front before investing in their spaghetti product, and the customer gets a free lunch. Savoia states, if there’s a market, there is a way. Thus it is important to find out what the market wants.


Savoia cites examples of companies that spent fortunes up front but then failed. Savoia stresses that you must have the right idea, of course, but the timing of delivery of a product is also critical. It’s important to remember that you can fall in love with your idea and be blinded by that, ignoring the negative data, and heading full speed toward potential failure at launch.


And finally, Savoia explains that he practices what he preaches for he actually pretotyped his book before writing the full version. And seeing his shortened version of the book takes off, he then knew that he needed to launch it fully. 


Savoia is the recipient of numerous awards recognizing him as a true pioneer in the area of business innovation, such as: Wall Street Journal Technical Innovator Award (2005), InfoWorld Top 25 CTOs Award (2005), Software Development Magazine Jolt Award (2005, 2006, 2007, 2008), InfoWorld's Technology of the Year Award (2005, 2006), JavaOne Duke Award for Technical Excellence (2005), and many more. 


Ketogenic Diets & Disease Treatment – Beth Zupec-Kania, RDN, CD – The Amazing Power of Nutrition, a Ketogenic Pathway to Better Health

Jan 10, 2019 40:21

Description:

Beth Zupec-Kania, RDN, CD, noted ketogenic diet and nutrition expert, lecturer, and top consultant for The Charlie Foundation, provides extensive information on good nutrition and how the ketogenic diet helps fight certain diseases.


Nutrition expert, Beth Zupec-Kania, is a registered and certified dietitian and nutritionist. She has amassed over 25 years of experience as a consultant and coach for medical professionals, patients, and individuals, on the power of nutritional ketosis for combatting select neurological disorders, and certain types of cancers and metabolic-based health problems. Zupec-Kania has been associated with The Charlie Foundation for many years where she continues to spread the word on the power of nutrition and keto for everyone. Her impressive resume, global reputation, and research in the field are but three of the many reasons why over 250 medical centers have attended her seminars and workshops for medical professionals at The Charlie Foundation.


Zupec-Kania’s primary work is promoting ketogenic diet therapy as a means to help children with inherited metabolic disorders. Additionally, she seeks to offer solutions and nutritional assistance for anyone who is required to exist on a blenderized diet, which is a diet of foods and liquids that are thinned in a blender for those with special conditions. Zupec-Kania works with her patients to make a personalized plan that is tailored to their specific nutritional and medical needs.


The nutrition guru recounts her motivation for devoting her life to nutrition and health. Zupec-Kania’s father was a cancer patient and she witnessed the harsh chemo and radiation sessions that her father endured that seemingly offered little or no help at all in regard to his condition. Motivated to help others and find a better way, at college prep school she declared her area of study as nutrition and her journey began. 


Zupec-Kania discusses the ketogenic diet’s rise at the Mayo Clinic, first introduced as a method for treating epilepsy patients. Zupec-Kania states that keto was also being studied at about the same time in Germany, as a treatment for cancer. And after many years, the medical community is now beginning to accept keto as a means of treating select types of cancer. 


Zupec-Kania outlines the various beneficial mechanisms of a ketogenic diet. She discusses cancer and states that it is an inflammatory process. As the ketogenic diet has a powerful anti-inflammatory effect it is a good option for people with certain types of cancers. She explains how glucose feeds tumor cells and how a ketogenic diet can help to cut off cancer cells’ energy supply. Zupec-Kania remembers patients with whom she has worked and recounts stories of those who saw improvement after beginning, and sticking with, their ketogenic diet. She states that while the power of keto is obvious, unfortunately, many doctors and healthcare professionals are still not aware of the benefits it may provide to their patients.


Zupec-Kania outlines her process, as she works with patients to devise a tailored strategy for their degree of ketosis, which takes into account all their medical factors, goals, and general issues. She provides detailed information about exogenous ketones and benefits they may provide to some individuals. And Zupec-Kania explains medium-chain fats that are ketotic producing, such as coconut oil and MCT oil, etc. 


Zupec-Kania discusses cancer patients who have experienced dramatic improvements, sometimes even putting their cancer into remission. Results are varied, of course, but most patients express, at minimum, feeling better overall when on a ketogenic diet. Zupec-Kania stresses the importance of starting early, however, and not waiting, for an early start to a ketogenic diet can sometimes have a profound impact on certain diseases and conditions.

Dr. Xi (Charlie) Ren, Assistant Professor of Biomedical Engineering at the College of Engineering, Carnegie Mellon University – Biomedical Engineering—Viable Organ Regeneration

Jan 10, 2019 29:11

Description:

Dr. Xi (Charlie) Ren, assistant professor of biomedical engineering at the College of Engineering, Carnegie Mellon University, delivers a detailed overview of his lab’s mission to provide regenerative therapeutic solutions to repair or replace damaged tissues and organs.


Xi Ren focused on developmental biology during his graduate study, specifically, vascular and hematopoietic systems. He later joined the Laboratory for Organ Engineering and Regeneration at Massachusetts General Hospital and Harvard Medical School as a Postdoctoral Research Fellow. Xi Ren was named Instructor in Surgery at Harvard Medical School in 2016. During his tenure, he developed systematic strategies for engineering functional vasculature based on decellularized organ scaffolds. Xi Ren became a member of the faculty at the Department of Biomedical Engineering at Carnegie Mellon University in 2017. Xi Ren earned a BS in biological science, as well as a Ph.D. in cell biology from the prestigious and highly ranked, Peking University in China.


Xi Ren discusses his work at the Ren Lab, specifically the interface of biomaterial and stem cell engineering with a primary objective to successfully provide regenerative therapeutic solutions to repair or replace damaged tissues and organs. The Ren Lab’s other prime areas of interest in exploration and research are vascular engineering, extracellular matrix engineering, cardiopulmonary engineering, and whole organ decellularization and regeneration. The Ren Lab is working to develop biologically selective and chemoselective approaches enabling extracellular matrix modulation and functionalization to stimulate injury repair in vivo and whole-organ bioengineering in vitro. Xi Ren talks about the shortage of lungs and livers and how his lab is working on ways to bioengineer lungs and livers with very similar structure and composition to their native counterparts, for transplantation. He discusses the details of organ structure and the difficulty of developing biomedically-engineered models of native organs.


The biomedical engineering expert talks about the limitations in his area of research and the importance of gathering excellent cells for lung reconstruction. And while stem cell biology is progressing, limitations still exist. He details the ways cells are used in regard to regeneration, discussing scaffolding, functionality, phenotypes, etc., and other issues. Xi Ren discusses bringing different cell types together to do a single job, to make a good functional organ, and the importance of organization in the process of organ regeneration. He details the methods utilized to work with purified cells and maintain them, and how it is possible to work with multiple cells within a specific organ. 


Xi Ren talks about vasculature regarding transplantations, and how many organs’ key function is in their interaction with blood. He discusses the various vasculatures of multiple organs and their distinct characteristics that play a role in functioning. Further, Xi Ren expounds upon some areas of research he expects to see expand in the future. 


The vascular network permeates literally every tissue and organ, and displays unique structures and properties to meet organ-specific functions as well as physiology. The Ren Lab’s research seeks to understand the molecule profiles behind organ-specific vascular phenotypes with the ultimate goal of engineering organ-specific vasculature.

The Long-Known Vesicle Bringing Brand New Insights on Epigenetic Inheritance and Disease Processes—Denis Noble—Biologist and Contributing Author of Exosomes in Health and Disease

Jan 10, 2019 1:08:36

Description:

Just around the corner is the publication of Exosomes in Health and Disease, an enormous compilation of data on exosomes and their role in almost every disease you can imagine. What’s an exosome, you might ask? At just a fraction of the size of even the smallest bacteria, exosomes are tiny vesicles communicating with and carrying information to cells anywhere in the body. We’ve known about them for decades, but a recent discovery holds huge implications for our understanding of epigenetics, epigenetic inheritance, and the causes of diseases.


Denis Noble, physiologist, researcher, and former Chair of Cardiovascular Physiology at the University of Oxford joins the podcast today to offer a fascinating conversation about the presence of epigenetic data within exosomes, their ability to control the genome of other cells by simply communicating with them, and the profile components that could indicate cancer or a particular disease state.


He also discusses the techniques used to extract such small vesicles from blood plasma and the challenges that this process has brought about, the transmission of epigenetic information by exosomes through the germline, symbiogenesis, and more.


Tune in for all the details.

Mental and Emotional Health as a Prerequisite for Losing Weight and Getting Fit—Drew Manning—Fit2Fat2Fit

Jan 9, 2019 34:10

Description:

“It all stems back to my Fit2Fat2Fit journey, where I learned just how wrong I was with my approach to trying to transform people; I could give someone the best meal plans, I could give them the best workouts, I could give them the best hacks to optimize their brain and their body from a physical perspective, but none of that matters unless a person knows to how to overcome their own mental and emotional challenges…so that’s what I hope to bring to the fitness industry,” says Drew Manning, who simply couldn’t understand why it was so difficult for his clients to stick to a meal and exercise plan in order to lose weight and get fit.


What did he do? He decided to truly “walk the walk”: he quit working out and indulged an unrestricted typical American diet filled with processed foods for six months, gained 75 pounds, and saw his health rapidly decline before working his way back to being fit and healthy. What he learned along the way is that the aspects of mental and emotional health are largely overlooked in the health and fitness industry, but absolutely essential to becoming healthy and fit.


Drew Manning will be speaking on this topic at the 2019 Metabolic Health Summit slated for January 31-February 3, and his latest book, Complete Keto, will be released on February 12th. It's a compilation of the latest and greatest keto research and contains a 30-day program that relies heavily on lessons from his Fit2Fat2Fit journey. It’s available now for pre-order on Amazon and Barnes and Noble. 


Tune in for the full conversation and check out <a href="http://fit2fat2fit.com">fit2fat2fit.com</a> for more.

Understanding Narcolepsy and Common Sleep Disorders—Ellen Wermter—Board-Certified Family Nurse Practitioner in Sleep Medicine

Jan 9, 2019 39:21

Description:

As a board-certified family nurse practitioner working in a sleep medicine clinic, Ellen Wermter has seen a wide variety of sleep disorders, including severe cases of sleep apnea, insomnia, narcolepsy, and restless leg syndrome. She joins the podcast to discuss what she sees from this unique perspective—one that isn’t often portrayed at all or portrayed correctly in the media. For example, she explains that narcolepsy is not only underrecognized but also misunderstood by many people; contrary to popular belief, the main presentation of narcolepsy is excessive daytime sleepiness—not unexpected episodes of falling to the ground and entering a deep sleep.


Wermter discusses how “excessive daytime sleepiness” is defined and identified clinically, the causes of narcolepsy—which are likely both genetic and environmental in nature—and one of the newest types of treatment for narcolepsy, which is not yet FDA-approved, but can be used in the US through a program called PEACE since it's been shown to be successful in Europe.


She also discusses sleep paralysis and cataplexy, which happen when the REM stage of sleep intrudes on the waking hours, one of the lesser common symptoms of sleep apnea, and how sleep studies work—despite the challenges.


Tune in for the full conversation, and find resources by visiting the Narcolepsy Network, Project Sleep, the National Sleep Foundation, and local support groups.

Clinical Metabolomics: Metabolites as Diagnostic Tools and the Potential for Novel Treatments—Martin Giera, PhD—Associate Professor at Leiden University

Jan 9, 2019 29:18

Description:

Dr. Martin Giera is an associate professor at Leiden University researching clinical metabolomics, the study of metabolites and how they take part in biochemical processes. Ultimately, the goal is to gain a deeper understanding of human physiology and the physiological processes of specific diseases, which could open the door to novel treatments and diagnostic processes for cancer and other diseases which we don’t currently understand.


Dr. Giera discusses a range of topics, including the role of the microbiome in metabolism, the Warburg effect, how the metabolic differences between different types of cancers indicate the need for personalized therapy for cancer, and what’s on the horizon for him and his team in the coming months. Tune in for all the details.

Cutting Carbs – Eric C. Westman, MD, MHS, Chief Medical Officer of HEAL Clinics – Reducing Carbohydrate Intake for Weight Loss and Diabetes Remission

Jan 7, 2019 37:34

Description:

Eric C. Westman, MD, MHS, chief medical officer of HEAL Clinics (healclinics.com), specializing in diabetes remission and weight loss, delivers a thorough analysis on the nutritional and medical significance of carbohydrate reduction.


Dr. Westman has a deep level of experience in medicine with a specialization in lifestyle-related conditions and illnesses, such as obesity and diabetes, as well as other medical issues, treatments, and research. He is the co-founder and chief medical officer of HEAL Clinics. Dr. Westman’s clinics are the creators of HEALcare, a comprehensive treatment plan for obesity, pre-diabetes, and type 2 diabetes that integrates personalized keto dietary and nutrition coaching with group behavioral coaching, as well as any needed medical care. HEALcare is a non-medical weight-loss program implemented by specialized counselors who have already brought about dramatic, significant changes in their own lives by adapting ketogenic lifestyles. HEALcare is medically supervised and thus offers complete obesity and diabetes treatment program. 

In addition to his intensive work at HEAL Clinics, 


Dr. Westman is also the director of the Duke Lifestyle Medicine Clinic, and medical director of the Duke Center for Smoking Cessation. Dr. Westman is a board certified doctor in internal medicine as well as obesity medicine. He is the co-editor of, Obesity: Evaluation and Treatment Essentials, and co-author of The New Atkins for a New You: The Ultimate Diet for Shedding Weight and Feeling Great, and Cholesterol Clarity: What the HDL Is Wrong with My Numbers?


Dr. Westman discusses his intensive research as an internal medicine and obesity doctor focused on the body’s ability to create its own ketones by cutting out carbohydrates. He explains the difference between exogenous and endogenous ketones, and some of the fallacies and breakthroughs in nutrition-based research. Dr. Westman talks about his early work at Duke University and experimentation in clinic trials that motivated him to devote more time to studying how nutrition impacts the body. He states that over the last few decades, research has demonstrated that cutting carbs has a significant impact actually. By cutting out the carbs, the body begins to burn its own fat. The big shift in thinking came when the medical community began to understand that the governmental guidelines issued in the 70s promoting carbohydrates were not truly the best advice. The outdated guidelines promoted avoiding fats and eating healthy carbohydrates, neither of which was based in evidence. 


Dr. Westman talks in-depth about the specifics of keto, and how the reduction of sugar, eating healthy fats, etc. is good for the body. He talks about the impact of keto on the body and the importance of still considering calories in regard to weight loss. It’s possible to ingest too much of a good thing, meaning that even if the foods and oils are extremely healthy, a very high caloric intake can certainly prevent weight loss from occurring. As everyone has their own metabolism, individuals will experience variations as they work toward finding their perfect diet for great health. Dr. Westman discusses Harvard research and Duke University studies that deal with weight gain, metabolic rate, etc., as well as the importance of caloric deficits for losing weight. But ultimately, most people can probably eat more and still lose weight when on a keto diet, as opposed to other diets.


Dr. Westman details how he works with patients, outlining his preferences such as beginning work with diabetes patients before they are put on a medication regimen. Dr. Westman states that all patients should be given a choice, and that diet and lifestyle changes can reverse the condition without medications. He talks about metabolic rate in regard to eating habits, such as intermittent fasting, etc. Regarding keto, and carb-cutting success, Dr. Westman discusses the early studies and trial and error approaches to cutting carbs such as were developed by Dr. Atkins, and others. And he adds that proper carb intake amounts for individuals seeking to achieve optimum health and weight loss/management are certainly related to age and activity level. Younger, more active people, as you would expect, can eat more carbs daily and still see results. Older and/or more sedentary individuals may need to restrict carb intake more significantly.


Dr. Westman is currently the president of the American Society of Bariatric Physicians, and a fellow of the Obesity Society and the Society of General Internal Medicine. His extensive clinical research includes more than 45 peer-reviewed papers on the efficacy of ketogenic diets and lifestyle in the management of type 2 diabetes, pre-diabetes, and obesity. 

Peter Csathy, Founder and Chairman of CREATV Media, LLC – Virtual and Immersive Experiences, the Advancing Technologies That Are Changing the Way We Experience Our World

Jan 7, 2019 31:41

Description:

Peter Csathy, founder and chairman of CREATV Media, LLC (<a href="http://creatv.media">creatv.media</a>), delivers an insightful overview of new media and technology, and the immersive experience.


Csathy is an experienced media and technology entrepreneur—equal parts connector, advisor, investor, entrepreneur, executive, and strategic thinker. He spent his early career in traditional media then expanded along with the advancing technologies into new media and digital platforms. His long and impressive resume includes important leadership roles with multiple highly successful companies in the tech and media space. Csathy is the former CEO of many leading media companies and is an internationally recognized media and technology expert.


Csathy has received many accolades for his books covering the topics of his expertise. Forbes referred to his book, Media 2.0 (18): An Insider's Guide to Today's Digital Media World & Where It's Going, as "an invaluable guide to the new media universe" and Variety stated it was “brilliant and compelling” and a “must-read.”


Csathy talks about CREATV Media’s mission as a media, entertainment, and tech business advisory firm working with companies that are pushing boundaries and the edge of creativity. CREATV Media is an advanced advisory service firm in the media/tech space and is recognized as an industry leader. Csathy’s firm offers specialized access to an impressive network of media, entertainment, and technology leaders, and powerful influencers. Csathy states that his team is comprised of connectors, dealmakers, and ‘opportunity’ spotters. 


Csathy discusses some of his early companies and investments in the media, music, and tech space. He delves into the changing immersive space, that goes beyond VR, and takes it into a real world experience, bringing the technology into the field where users can walk around and interact with others. Csathy details his exciting immersive projects with Vortex Immersion Media, Inc., an advanced tech company of which he serves as chairman. Vortex Immersion Media produces innovative dome experiences, in which users can experience music and visuals in a 360-degree environment that envelope you in a 3D, virtual reality type experience.


The media expert talks about his vision for future immersive experiences, such as immersive escape rooms where people can literally escape to other worlds or environments for relaxation and play, etc. He explains how the technology can truly impact our perceptions in a real way, physiologically. Csathy gives an overview of some immersive experiences hospitals are implementing for children with illnesses, providing immersive environments that allow them to experience snow covered mountains, or other natural worlds that provide relief and comfort, and are fun. And amazingly, the children experience physiological impacts that actually reduce their physical pain in the same manner that drugs do.


Csathy discusses innovative media such as Netflix’s release of “Black Mirror: Bandersnatch,” one of the first truly interactive movie experiences ever released on a mass scale. Netflix created multiple experiences, variations on story lines, that allow a viewer to choose the path the story takes. As technology continues to advance, the opportunity to bring new, immersive experiences to users is immense. An immersive experience can bring new audiences to art and expressive media. Csathy discusses his excitement about using advancing technologies to essentially bring many musical artists back into the public eye in a unique manner, experiencing their artistry in entirely new ways—opening up younger generations to great music of the past. 


The media guru expounds upon some of the technology that is changing the Hollywood industry, and his expectations for media in the coming years. Additionally, he discusses some of the topics and issues he writes about in his book, as well as in periodicals of note. Csathy’s thoughts and perspectives on the nexus of technology and media are regularly featured in The Wall Street Journal, TechCrunch, Venturebeat, Variety, The Hollywood Reporter, The New York Times, Los Angeles Times, TheWrap, Billboard, USA Today, and many more. Csathy is a board member and advisor to multiple media and tech companies.

John Hamilton, CEO of UNLTD, Developers of VR, AR, & Hybrid Experiences–Changing the Game in Virtual & Augmented Reality

Jan 2, 2019 26:15

Description:

John Hamilton, CEO of UNLTD (go-unlimited.co), a company that is blazing the trail forward in the design, creation, and branding of high-end virtual reality experiences, delivers an interesting overview of the advances in virtual and augmented reality.


Hamilton talks about his background, and starting out in the film industry as a producer and distribution executive. He recounts how his first interaction with a true VR experience so impressed him that he was hooked, and had to find a way to explore this exciting new area, bringing all of his business experience to the burgeoning VR and AR (augmented reality) media platforms.


Hamilton’s company, UNLTD, seeks to push the boundaries of the industry, creating new experiences that combine all available technologies in the space. Virtual and augmented reality are exciting new mediums—hybrids between interactive media, immersive and dramatic cinematic content, and mobile experiences. UNLTD offers branded and original VR/360/AR content for groundbreaking immersive and interactive media that includes film, gaming, series, apps, and advertising. Specifically, UNLTD has expertise in directing and developing VR arcade installations, content production, virtual reality, augmented reality, interactivity, 360 visual effects, and 3D environments.


Hamilton explains the details of VR, AR, and mixed or hybrid reality experiences, and how each works. He details how an individual experiences each, from screen to headset, etc. or combinations that come together to create a completely immersive experience. He talks about his earlier work in VR for film and branding, and how he and his partners shifted their focus to encompass new media experiences for multiple industries from oil & gas, to medical, and beyond. He states that their primary focus, and the source of their greatest revenue, will be in the enterprise market. Enterprise marketing is essentially a development strategy to retain an existing customer base while generating new active leads via integrated, multichannel campaigns. Hamilton talks about their clients and the reasons why they come to UNLTD to rebrand or get moving in a new exciting direction to grow their business.

The VR guru discusses how they bring their unique storytelling skills to every new project, for not only an immersive experience, but also one that cannot become boring, due to the creative story that is developed for the experience. Hamilton cites specific examples of their work and projects. He provides an overview of a particular oil & gas project UNLTD developed that is essentially a game simulation which allows users to perform the requisite checks to ensure all is in working order, from checking a manifold for proper connection, to reviewing inspection dates on equipment, and much more. He states that this type of simulation is a highly effective way to train people in a safe environment before they even take one step onto a ship, so they can be prepared for their jobs in onloading or offloading or whatever it may be.


Hamilton enthusiastically discusses a new experience/show called Trinity, which his team has developed and is very excited about. Trinity is an immersive, interactive, virtual reality sci-fi experience that incorporates live-action characters, big budget movie VFX, and the most trendsetting interactive design. He outlines some of the details of their volumetric capture and how they were able to go back and forth between live and volumetric. Volumetric video is a progressive technique that captures a three dimensional space, such as a specific location or performance. With this process you can acquire data that can then be viewed on flat screens as well as via 3D displays and VR goggles.


UNLTD generates tailored, branded and original VR content for truly interactive media experiences, including films, games, series, advertising, promotional stunts, rides, as well as for educational and medical applications, and other industries.

Health Help – David Korsunsky, Founder and CEO of Heads Up Health – Organizing Health Data, Monitoring Trending Factors & Taking Charge of Our Overall Health

Jan 2, 2019 26:54

Description:

David Korsunsky, founder and CEO of Heads Up Health, delivers an important overview of the current state of health information and steps we can all take to organize our health data. 


For more than 15 years Korsunsky has been a business leader, leading technology firms and forming strategic alliances. Recently, Korsunsky served as Director of Technical Alliances at VMware, Inc. where he led partnerships with global EHR companies such as GE, EPIC, Cerner, McKesson, Allscripts, and others. Korsunsky is active and believes in a healthy lifestyle, and it was his passion for good health that inspired him to find a new way to innovate in the healthcare space. Korsunsky sought to create a means for everyone to take charge of their health, by accessing important markers that elucidate where they are on the path to optimum health. 


Korsunsky talks about his sources of inspiration, from nutritionists to select nonconventional health advocates, who introduced him to a trove of information that was not always the go-to for traditional medicine practitioners. Realizing how his own personal medical information was literally scattered all over the place from healthcare office to office and patient portal to portal, Korsunsky knew there had to be a better way. He had a tremendous desire to find a way to connect his lifestyle choices with the blood work that would bear out his theories on diet and exercise, etc. Korsunsky founded Heads Up Health, a company that seeks to empower people, helping them to transform their health through the use of state of the art tracking tools. His team of experienced and knowledgeable health-conscious technology experts wanted to clean up the current system fraught with confusing medical records, underutilized health-tracking technologies, and poorly managed health data. Korsunsky saw a way to implement a software solution to clean up the mess and get to the heart of the matter—improving health for everyone by connecting them to their own data. 


The healthcare tech expert discusses how important trend lines can be totally missed by physicians when health records are scattered and unorganized. And when physicians cannot see the full picture over a long period of time, they are unfortunately less aptly equipped to make the best decisions on long-term care plans for treatment or general health advice. Korsunsky states that the onus is upon the patient, in most systems, for them to be their own advocate and investigate deeply into their own personal medical issues. He details how these markers of our health, the look into our blood work and body chemistry, are essentially our longevity numbers and it is important for individuals to know where they stand, to understand what needs work or improvement. 


Korsunsky outlines how their platform works and how users can enter their medical data and get active right away at tracking their health and making improvements. He discusses some of the important aspects of their system, such as tracking HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) scores, which as he states is significantly better than simply looking at blood sugar. He explains how their platform actually collects data while we sleep, from heart rate to core temperature and beyond, to calculate a score and overall assessment of our recovery during sleep. Additionally, he elaborates on public data sets and useful information that he wants their users to have access to through the platform, to allow them to be notified about pharmaceutical news and more that could affect them. 


Korsunsky discusses their growth as a small company on the rise. He details how it is important to build out their system slowly and organically. Currently, they have tens of thousands of users and are growing via word of mouth. As their product is an intricate product its pace of growth is carefully controlled by Korsunsky and his team of developers. 


Korsunsky enthusiastically discusses the personal fulfillment he experiences when he hears stories of users who have learned to successfully manage or reduce certain chronic health problems by getting a handle on their data and working toward solutions to improve health. Based on his team’s core belief that superbly organized data is a critical key to improving and optimizing health, Heads Up Health has created a central space where anyone can manage and explore the important information that is crucial to maintaining great health or improving their health issues

The Thyroid Dilemma – Elle Russ, Wellness Advocate and Author of The Paleo Thyroid Solution – Thyroid Health – The Many Issues That Originate With This Master Gland & The Way To Better Health

Jan 2, 2019 36:47

Description:

Elle Russ, wellness advocate and author of The Paleo Thyroid Solution, provides a wealth of knowledge on thyroid issues and explains how millions of people remain undiagnosed and suffer needlessly.


Elle Russ is a sought-after guest on many wellness-oriented shows and interviewee of wellness-related blogs and magazines. Her celebrated book, The Paleo Thyroid Solution, is a bestseller on Amazon and has made her a noted voice in the paleo, primal, and ancestral health movement. Russ is also the popular host of The Primal Blueprint Podcast, a top-ranked health show created by food blogger, former distance runner, triathlete, and well known New York Times Bestselling author, Mark Sisson.


Russ discusses her serious bouts with hypothyroidism, how it impacted her life, and how none of her doctors were offering much help. With over 30 symptoms, Russ started digging deeper to discover the root of her health maladies. She details how so many common issues from depression to cholesterol problems to high blood pressure are directly related to the thyroid. As she states, the thyroid is the master gland of the human body, without a doubt. From metabolism to production of hormones, the thyroid is the source from which many bodily functions and systems are maintained or regulated. Brain fog, exhaustion, inability to lose weight, etc., the list goes on and on, and the thyroid is the key to so much in our body and its systems. 


Russ elaborates on the many and various antibody tests, and others, that help to define potential thyroid issues. As she states, over 20 million people in the US suffer from thyroid-related issues, but sadly 60% are undiagnosed and struggle with symptoms from which they can find no relief. Her book covers many important topics such as paleo protocols for preventing and reversing low thyroid function, the correct blood tests to diagnose hypothyroidism and how to treat it, how to diagnose and treat Reverse T3 issues, how to lose weight gained because of hypothyroidism, and much more.


She discusses the importance of nutritional experimentation and elimination of foods that contribute to problems, as well as many other issues that have a direct impact on health. She talks about brand name versus generic pharmaceuticals and details some specific drugs in which the generic version could be contributing to more or other problems or symptoms. She outlines specifics of T3 and T4 drugs and hormone replacement therapy. Triiodothyronine (T3) and thyroxine (T4) are the two major hormones produced by the thyroid gland. There are many factors that are important, but one particularly important issue is to make sure your drug choice is suited for you, and that your lab work provides proof that whatever combination therapy you are on, that it is working for you. She discusses the many inaccurate assessments the healthcare industry has made regarding thyroid and thyroid drug issues. 


The thyroid health guru talks about fluctuating signals and lab indicators, and the importance of seeing the big picture when interpreting results and implementing treatment and drug plans. And importantly, she underscores that physicians need to look at multiple test results and not just one or two to properly diagnose these issues. Russ relates how her struggle to find the answers to her own health problems really motivated her to help others, and that is just what she does day in and day out.


Help, I Can’t Sleep! – Michael A. Tompkins, PhD, ABPP, Co-Director of the San Francisco Bay Area Center for Cognitive Therapy – The Importance of Sleep – Why We Need It and What To Do When We Aren’t Getting Enough Quality Sleep

Jan 1, 2019 37:18

Description:

Michael A. Tompkins, PhD, ABPP, co-director of the San Francisco Bay Area Center for Cognitive Therapy (sfbacct.com), delivers an informative overview of mental health issues and contributing factors that play a significant role in how we sleep and the quality of our sleep.


Dr. Tompkins is an experienced licensed psychologist, board certified in behavioral and cognitive psychology. He is an accomplished author and outspoken advocate for mental health. Dr. Tompkins has held, and currently holds, significant leadership roles with various, important mental health centers and educational institutions. He is co-director of the San Francisco Bay Area Center for Cognitive Therapy, assistant clinical professor at the University of California, Berkeley, as well as Diplomate and Founding Fellow of the Academy of Cognitive Therapy. Additionally, Dr. Tompkins works as a trainer and consultant for the Beck Institute for Cognitive Behavior.


Dr. Tompkins discusses his nearly 30-year career in mental health, treating primarily anxiety and mood disorders. He states that most people with these kinds of disorders do experience difficulty with sleep. He details CBTI (cognitive behavioral therapy for insomnia) and his work with teens who have anxiety and sleep disorders. Insomnia is defined as a difficulty going to sleep or staying asleep, which limits the amount of restorative sleep that we all need. He explains how sleep disrupters, such as stress or travel, impact the sleep cycle. Further, he states that those who struggle to get quality sleep often worry about it, which increases anxiety and exacerbates the problem, or they try to adjust their sleep schedule, which often does not work because regularity of a sleep schedule is critical for the body to get into a working pattern such that restorative sleep can flourish.


Dr. Tompkins’ book, The Insomnia Workbook for Teens, lays out a step-by-step process for achieving better sleep, proven-effective strategies to help the sleep deprived get to sleep and stay asleep. The book explains the many and varied reasons we experience insomnia, and offers advice on how to target and deal with sleep disrupters such as caffeine and sugar. Teens especially need quality sleep as their lifestyles today are fast and furious, and it is difficult to rise to the challenges of each day when we’re sleep deprived and left feeling exhausted, grouchy, and unprepared for daily tasks. Dr. Tompkins coauthored the book with his esteemed colleague, Dr. Monique Thompson, also a licensed clinical psychologist. Dr. Thompson holds a master’s degree from the University of Pennsylvania and a doctoral degree in clinical psychology from California School of Professional Psychology. She is a certified cognitive therapist and also a Diplomate of the Academy of Cognitive Therapy. She treats a myriad of mental health issues such as depression, various anxiety disorders (social anxiety, phobias, and panic), and sleep disorders, as well as attention problems, life transitions, and more.


Dr. Tompkins provides an overview of one of their primary goals: focusing on sleep efficiency, which is entirely different than simply looking at quality or quantity of sleep. He discusses various stimulus control strategies and other methods that people can utilize to help get them back on track with their sleep. He states that nearly 80% of the individuals they help with primary insomnia can often benefit from sleep restriction, essentially getting them to stop trying to catch up on sleep, but to focus on having consistent go to bed, and get out of bed times. Additionally he discusses other effective techniques such as breathing exercises, mindful meditation, muscle relaxation, and more. Dr. Tompkins talks about wind down routines and relaxation in general, and the importance of getting one’s body and mind to a state in which all systems are ready to fall asleep willingly.


The sleep specialist and mental health educator discusses the particular issues that teens face, as they are literally going through an organic change in brain development that causes them to want to begin sleep later in the evening and then sleep in later come morning. And with elevated stress in teens’ lives, and the use of social media, all can keep teen minds activated, which leads to sleep disturbances or a general difficulty with falling asleep or staying asleep. He details the types of skills that they teach in CBTI to help teens with their various sleep issues.


Dr. Tompkins discusses melatonin and other supplements, but he stresses that chronic insomnia sufferers may not benefit from melatonin, etc. Ultimately, insomnia sufferers must find a way to focus on wind down time and a consistent schedule of sleep. Additionally he talks about genetic inheritances that may contribute to sleep problems, such as chronotype (when we feel like sleeping naturally) and mental arousability, which many insomniacs tend to be prone to.


Dr. Tompkins is the author of multiple scholarly articles, chapters on cognitive behavior therapy, and books covering related subjects. He treats adults, adolescents, and children with anxiety disorders, as well as obsessive compulsive disorder, health anxiety, stress, insomnia, repetitive behaviors, elimination disorders, Tourette’s and tic disorders.

Acoustic Ascension – Mark Fischer-Colbrie, President and CEO of Labcyte – Echo Acoustic Liquid Dispensing Technology That Has Upended the Scientific World Allowing for Experimental Breakthroughs and Development of New Drugs

Jan 1, 2019 24:01

Description:

Mark Fischer-Colbrie, president and CEO of Labcyte (labcyte.com), provides an extensive overview and introduction into the groundbreaking developments in liquid handling and transfer for experimentation.


Fischer-Colbrie is a seasoned executive with over 30 years of experience in the development and launch of innovative products for diagnostics, medical devices, therapeutics, and specific technologies for advancing companies. And since 2008, Fischer-Colbrie has helmed Labcyte as its president and CEO. Other notable positions in his storied career are as follows: senior vice president of finance and administration and chief financial officer at Adeza Biomedical Corporation, a successful women’s healthcare startup that sold for $450 million; and as vice-president, corporate controller, and advanced technology business manager at a disk drive manufacturer that grew from a small startup to a behemoth $1.2 billion in revenue. During his tenure at Adeza, Fischer-Colbrie was an inventor on 4 patents and 6 patent applications and headed the business development area of the company for three years. He holds a bachelor’s degree from Stanford University and an MBA in marketing and finance from UC Berkeley. 


Fischer-Colbrie discusses Labcyte’s mission to advance scientific innovations with sound. Labcyte seeks to redefine liquid handling for drug discovery and development, genomics, personalized medicine, synthetic biology, and more. He states that because the novel process of transferring liquids is governed by sound waves, it allows for replication of every single transfer in the same way with such precise uniformity and consistency that it generates better scientific data and more significant results during experimentation for various industries. The accuracy has provided experimenters an opportunity to explore new avenues for experimentation that were not previously available with traditional techniques. 


The scientific research innovator elaborates on the many problems and errors that arise when using standard pipettes in experimentation, such as liquids being in touch with surfaces, drops, cross contamination, sterility, etc. Labcyte’s innovative technology eliminates all these problems and errors and provides researchers with a more precise way to conduct experimentation and research. And this new technique is enabling new drugs to be discovered that simply could not have been with the old, less accurate, potentially error-prone techniques.


Fischer-Colbrie explains how a wide variety of experiments can be engaged in now with the more accurate Labcyte process. He explains the minute details of how the system works, covering topics such as surface tension, viscosity, and targeting. He outlines how the advanced technology system has been adopted by pharmaceutical manufacturers across the globe for its unique ability to precisely experiment in ways that were not possible previously. He speaks about the tremendous precision of data that is now becoming available thanks to the process, that will impact uses for artificial intelligence.


Fischer-Colbrie highlights some specific examples of how Labcyte’s acoustic technique benefits industry, from increased precision and accuracy, to cost savings due to the elimination of expensive chemistry and pipettes, and through a significant reduction of time needed to conduct experimentation and gather results. Additionally, he states that the advanced technique will decrease the need for animal testing as well. 


Fischer-Colbrie is currently chairman of the board of the Juvenile Diabetes Research Foundation and also a board member of the Analytical, Life Science & Diagnostic Association. He was selected as National EY Entrepreneur Of The Year 2013, the country's most prestigious business award for entrepreneurs.


Transform Your Mindset, Reach Peak Performance, and Obtain Your Goals—Som Bathla—The Science of High Performance

Jan 1, 2019 36:12

Description:

Before becoming a full-time and successful writer, Som Bathla worked as a corporate lawyer for 17 years. Realizing it was time for a change, he set his sights on a new goal and began figuring out what it would take to get there. He did the same thing just a couple of years ago when he decided to do something about the fact that he was overweight: he began by making a decision to run 10 kilometers within 12 weeks, and then started figuring out how much preparation he would need to do, how he’d need to change his daily routine, and how he’d need to change his diet. Perhaps most importantly, he had to remain disciplined, and strike a balance between preparation and recuperation.


Bathla joins the podcast to discuss the main themes of his book, The Science of High Performance: Develop Mental Toughness, Boost Willpower, Master New Skills, and Achieve Your Goals Faster and offer the audience insight on his personal journey, the challenges he’s faced, and how he’s overcome the greatest obstacles. He also discusses the psychological concept of “flow” and the distinction between intrinsic and extrinsic value. 


Tune in for some inspiration and check out his book on Amazon.

Ruminations with Richard: The Power of the 80/20 Principle

Dec 31, 2018 11:50

Description:

Everything is skewed—whether in the businesses we own, the places we’re employed, the groups of friends we hang out with, or our daily routines, and achieving success can be as simple as locating those skews and learning how to capitalize on them. That’s the idea behind the 80/20 principle and the subject of this mini-episode with Richard Jacobs. 


He explains how he’s applied the principle through an analysis of his business and various product offerings, which has resulted in higher profits, improved efficiency, simpler procedures, and perhaps most importantly, happier clients. Along the same lines of thought, he explains how to use this principle to guide you toward the experts of the experts—the “superhumans”—in any given profession. 

Ethical and Transparent Data Collection for the Betterment of Humanity—Scott Nelson—Human Data Commons Foundation

Dec 31, 2018 33:23

Description:

Established just two and a half years ago, the Human Data Commons Foundation aims to address two primary questions: how do we make the best decisions around the best and most powerful sources of data available to us, and how do we put structures in place that encourage people to share their data in a way that protects their privacy and places them at the center of agency in how that data gets used?


“Companies realize that the more data they have, the better machine learning algorithms they can produce…and that brings with it enormous power…and enormous peril…there’s a lot of systemic injustice that can be perpetuated through these…and our intention at the foundation is to bring more attention to that,” says Scott Nelson, founder, and chair of the Human Data Commons Foundation.


One way in which they’re doing this is by publishing annual “report cards” that review data usage, privacy policies, terms of service, and the amount of agency given to users by the top companies in wearable technology such as Fitbit. The ultimate goal is to democratize, make more transparent, and advance human consciousness and conscious evolution through the responsible and ethical use of data.


Nelson touches on a variety of topics, including the main challenges to the implementation of new structures and processes in established company cultures, the role of blockchain technology in personal data protection, General Data Protection Regulation (GDPR), and how a couple of German projects could pave the way for the implementation of open-source, ethical data platforms in the U.S. 

Digging Up the Data Your Company Has, Needs, and Can’t Access—Paul Mendoza—SigParser

Dec 31, 2018 21:06

Description:

The average annual turnover rate for sales reps is about 36%, and 70% of companies need at least six months to bring a single sales rep on board and up to speed. What if these percentages could be significantly decreased by a third party company’s ability to quickly obtain and analyze all of an old rep’s customer contact information and accounts so that a new rep could hit the ground running—essentially picking up where the last left off?


This is just one use case of SigParser, a technology that employs machine learning algorithms to parse through business emails and extract the most pertinent information, including customers’ first and last names, phone numbers, and addresses. Once obtained, the information is loaded into the company’s customer relationship management system (CRM). Considering the fact that nearly 80% of contact information never makes it into a company’s CRM system, SigParser is an invaluable tool for building customer relations and increasing sales.


There’s also a stateless API version of the product for companies that want to be able to grab contacts but can’t have a third party processing and storing the data for them. Interested in learning more or finding out how SigParser can help your company? Paul Mendoza, CEO of SigParser, joins the podcast to explain all the ins and outs, so tune in and visit <a href="http://sigparser.com">sigparser.com</a>. 

Confronting the Growing Epidemic of Childhood Obesity—Dyan Hes, MD—Gramercy Pediatrics

Dec 28, 2018 32:15

Description:

As the medical director of Gramercy Pediatrics In New York City, Dr. Dyan Hes specializes in what’s become an epidemic over the past several decades: pediatric obesity. According to the CDC, approximately 19 percent or 13.7 million children in the U.S. are obese, and while it’s true that genetics can contribute to this in some families, as a whole the genetics of the human population has not changed enough to account for it. And it’s not just the U.S.—it’s a first-world problem that’s quickly spread to third world countries. So, what’s the deal?


Dr. Hes makes for an insightful and eye-opening conversation by sharing her expertise on the subject and the experiences she’s had with her patients, who range from infants to young adults suffering from one or more conditions due to obesity, including pre-diabetes, high blood pressure, asthma, insulin resistance, irregular menstrual cycles, and joint pain. According to Dr. Hes, kids are being given too much of the wrong types of food and not enough of the right types, especially from school cafeterias. 


On top of that, many school districts don’t have enough funding to provide physical education beyond 45 minutes per week. Add to the mixture an overall increase in sedentary lifestyles and reliance on technology, and you have the ingredients for this current epidemic.


Tune in to hear the full conversation and learn how to take the steps to start turning this around. For resources, visit the Obesity Action Coalition and American Board of Obesity Medicine websites and seek out local wellness programs in your area. To learn more about Dr. Hes’ work, visit <a href="http://gramercypediatrics.com.">gramercypediatrics.com.</a> 


Rethinking Genes, Understanding Epigenetics—David S. Moore, PhD—Psychological Field Group at Pitzer College

Dec 28, 2018 41:28

Description:

According to David Moore, PhD and faculty member in the Psychological Field Group at Pitzer College, there’s good reason to believe that “genes” as we’ve come to commonly understand them don’t actually exist; they aren’t segments of DNA which start and stop at discrete points, they don’t fulfill just one role in one context, and their expression or lack thereof is not immune to environmental influences. In fact, most molecular biologists would say that there is no single agreed-upon definition of a gene.


Dr. Moore joins the podcast to explore the topic of epigenetics: the phenomenon by which our experiences and environmental factors influence our genes and contribute to our characteristics. These environmental stimuli include the food we eat, how we exercise, the drugs we consume, our experiences in childhood, the level at which we socially interact as adults, and socioeconomic status. For example, a 2004 study conducted by Michael Meaney and Moshe Szyf showed an association between the level of grooming a pup receives from its mother and reactivity to stress in adulthood: the more grooming a pup received, the less reactive it was to stress stimuli as an adult. This finding, labelled by the authors as “epigenetic programming,” has been challenged by many, yet evidence that supports it continues to grow. 


This is just a snippet of the fascinating conversation Dr. Moore offers, which touches on topics such as in utero epigenetics, whether epigenetic states can be changed or reversed once they’ve been established, how the most common antidepressants have been shown to produce epigenetic changes, and the controversial idea that epigenetic changes are inheritable. He also discusses his most recent research, which involves studying mental rotation in human infants—an ability considered the single biggest sex difference in cognition that’s unrelated to reproduction.


Tune in for the details and visit http://pzacad.pitzer.edu/~dmoore/ to learn more. 

Empowering Small and Independent Businesses with the Technologies Used by Major Corporations—Alex Vincart, PhD—Enkidoo Technologies

Dec 27, 2018 16:54

Description:

Alex Vincart, Ph.D., is the CTO of Enkidoo Technologies, a platform that’s bringing small to medium-sized businesses and independent retailers access to the same AI and automation technologies harnessed by major corporations, benefiting them with better tools and better visibility for managing inventory. By connecting point of sale systems and aggregating large amounts of historical sales data, Enkidoo optimizes company supply chains and provides them with a reliable way to predict future sales. 


With each product offered through Smart Assistance, Enkidoo provides a streamlined and seamless process for business owners who want to do what they set out to from the beginning: foster the business itself without feeling bogged down by the constant operational demands.


Tune in for a discussion about the ins and outs of Enkidoo services, what’s rolling out in the next six months or so, and an interesting use case that combines IOT and AI. 


Interested in learning more? Check out <a href="http://enkidoo.ai">enkidoo.ai</a>.

Virtual Sales Associates Boosting Online and In-Store Retail Sales—Caroline Klatt—Headliner Labs

Dec 27, 2018 26:31

Description:

Caroline Klatt entered the world of ecommerce and retail when she was still in high school and quickly realized the primary objective: drive up sales by finding and encouraging consumers to make purchases. For decades now, companies have been trying to accomplish this by investing most of their funds in digital ads and then following up with potential customers via email. According to Klatt, however, this approach has not only become outdated, but ineffective; in a society where everyone is using messaging apps through their phones at almost all hours of the day, retailers must integrate themselves in consumers’ lives in the same way—by messaging them directly.


As the CEO and co-founder of Headliner Labs, Platt is giving retailers the ability to do this in a scalable and fully-automated way using artificial intelligence, and the result so far has been a 96 percent open rate, meaning potential customers are opening messages from retailers, communicating with them, and ultimately making purchases. Beyond the first layer of AI, retailers have the option of directing potential buyers to a live agent in order to maintain that ever-so-important personal touch and one-on-one communication.


Press play to learn how you can benefit from the services offered by Headliner Labs and what to look forward to in the coming months. Visit <a href="http://headlinerlabs.com">headlinerlabs.com</a> for more. 

From Pig to Human: Life-Saving Organ Transplants—Dr. Joseph Tector—University of Alabama Xenotransplant Program

Dec 27, 2018 24:47

Description:

Approximately 120,000 people in the U.S. alone are waiting for an organ transplant, and there are many more who could benefit from one but haven’t made the list because there simply aren’t enough organs available. But what if the supply could be increased by utilizing the organs of another species? The process is called xenotransplantation, and its what Dr. Joseph Tector and his team have been working on for years now.


As the director of the University of Alabama Xenotransplant Program, Dr. Tector explains the main roadblock to xenotransplantation: rejection by the receiver’s antibodies. However, he and his team have genetically modified pig organs in a way that—in conjunction with immunosuppressant drugs—will decrease or eliminate the human antibody response, thereby preventing rejection. Ten people on the waitlist have already been tested and shown to have no detectable antibodies to the pig cells, making them candidates for transplant.


Press play for all the details.

Earlier Detection and Accurate Predictions of Life-Threatening Conditions Using Machine Learning—Brandon K. Fornwalt and Aalpen Patel—Geisinger Department of Imaging Science and Innovation

Dec 21, 2018 34:30

Description:

A shortage of about 100,000 physicians is expected in the US by the year 2025, which will force many people into long waiting periods and delays in the detection and treatment of potentially life-threatening conditions. In terms of providing health care in a timely manner to the growing population, we are reaching the limits of human capacity. So, where do we turn? According to the team at Geisinger, the answer is machines.

Brandon K. Fornwalt, MD, PhD, and associate professor and director of the Geisinger Department of Imaging Science and Innovation, and Aalpen Patel, MD and Chair of the Geisinger System of Radiology join the podcast to discuss the problems with the current system of medicine and diagnostic imaging, how the implementation of machines and machine learning can help, and the specific projects they’re working on to improve patient outcomes and help physicians to be more efficient.


In a recent project, the team at Geisinger trained a computer model to predict death in patients by using over 700,000 videos of the heart. The result? The machine made predictions with an accuracy level far superior to that of clinicians, allowing for early intervention for heart attack and stroke. Tune in for a compelling discussion, detailed description of other projects in the works, and Geisinger’s long-term goals.


To learn more, check out geisinger.org.


Revolutionizing and Democratizing the Accessibility of Genomic Data—Paul Mola—Roswell Biotechnologies

Dec 21, 2018 30:16

Description:

Imagine visiting your primary care doctor and receiving a whole read out of your genomic data within 10 minutes for as little as $10, equipping your doctor with the information needed in order to deliver you individually tailored medical treatments and therapies. Thanks to the work being done at Roswell Biotechnologies, this is well on its way to becoming a reality.


As the founder, president, and CEO of Roswell Biotechnologies, Paul Mola realizes the need to sequence genomes at scale in order to obtain the level of understanding and interpretation needed for making precision medicine a reality. What we really need, he says, is a “genomic encyclopedia” of genetic variances and corresponding phenotypic descriptions, treatments, and drug therapies. Until now, the high cost and slow process of genomic sequencing has stymied this development and kept enormous amounts of useful information largely inaccessible and unaffordable for the average person.


Mola has discovered a viable solution by merging nanochemistry with CMOS technology (which is the same technology that’s used to manufacture computer chips), which allows for direct electronic monitoring of the process by which DNA is copied. It’s time-saving, cost-effective, and scalable, and there’s nothing else like it out there. Rather than taking 24 hours and costing $1,500 to sequence a genome, the Roswell solution will take just an hour and cost $100, and packs a ton of opportunities for improvement down the road.


Tune in for all the details and visit roswellbiotech.com to learn more.

Platform for Essential Communication in a World of Health Care Data Overload—Sandeep Jain, MD—ListenMD

Dec 21, 2018 26:37

Description:

Having practiced medicine for over 20 years now, Dr. Sandeep Jain has witnessed firsthand how the increasing predominance of electronic medical records has lowered the amount and damaged the quality of communication that occurs between doctors and patients and between members of a patient’s health care team. He argues that electronic medical record keeping has not only made communication across systems impossible by limiting doctors to their organizations or hospitals, but also subtracted from the patient experience by forcing providers to document excess data rather than simply listen to the patient. The problem is only worsened by the fact that doctors are monetarily incentivized to document through this system in a particular manner.


“Important, essential insight becomes a needle in a haystack, and doctors have to hide needles of information in a lot of hay because that’s how they make their own hay…money,” says Dr. Jain. But what if the needles could be shared without the hay and across systems so that a patient’s entire care team could be on the same page at the touch of a button? These were the ideas that compelled him to found ListenMD, a secure, HIPPA-compliant app that allows patients and every member of their treating team to communicate with one another in real time, sharing those essential bits of information that would otherwise get buried in the excess. The app also allows providers to delay less important messages and prioritize urgent ones, which keeps disturbances to a minimum and lessens the barrage of data doctors already deal with. 


There are many other features and perks of the app designed to simplify, streamline, and improve patient care. Tune in for more information and download the app to try it for yourself.  

We Are What We Eat – Dr. Daryl Gioffre, Celebrity Nutritionist, Author, Alkaline and Ketogenic Diet Expert – Losing Weight, Fighting Inflammation, and Increasing Energy and Overall Good Health

Dec 20, 2018 31:31

Description:

Dr. Daryl Gioffre, celebrity nutritionist, author, alkaline and ketogenic diet expert, gives a detailed presentation on the power of good nutrition and how everyone can make improvements for increased energy, better health, and longevity.


Dr. Gioffre has a lot of interests. He is a sought-after speaker and educator, a certified raw food chef, live blood microscopist, and reiki master. And as a former self-described sugar addict, he has found a way to lead a healthy life and has a passion for sharing his knowledge with everyone. Dr. Gioffre is particularly interested in the root causes of inflammation and chronic illnesses. His method involves moderation, using cutting-edge nutrition practices to achieve and maintain the best health possible. Dr. Gioffre is the founder of the Gioffre Chiropractic Wellness Center, as well as the popular brand and website, Alkamind. His celebrated book, Get Off Your Acid – 7 Steps in 7 Days to Lose Weight, Fight Inflammation, and Reclaim Your Health &amp; Energy has been attracting a lot of attention and intensifying the dialogue about good health and nutrition.


Dr. Gioffre discusses his path to good health, including his past issues with weight and nutrition, especially sugar. He states that as he followed the evidence, to understand his addiction to sugar, that that evidence led him to acid—acid was inflammatory to his body. He describes how he integrated nutritional elements into his diet, such as green juices, and reclaimed his energy, life, and lost weight dramatically, not to mention eliminating his sugar addiction in the process.


The nutrition expert discusses specific green juices, which are comprised mostly of vegetables and are highly alkalizing. He states that all green juices are certainly not created equal, so it is important to understand what makes a green juice healthy. In order for green juices to be alkaline they must be high in minerals, high in fiber, and low in sugar. He talks about the benefits of highly concentrated powders comprised of organic greens, which is an easy way to get a large amount of the right kinds of organic greens into your body without a lot of effort. Dr. Gioffre explains how taste buds can shift about every two weeks, so what you are putting into your body will affect how you respond to new foods and beverages. Thus once you make the switch to healthier options, your body’s taste buds will come on board and begin craving the good stuff. Dr. Gioffre states, shockingly, that research has shown sugar is literally eight times more powerful than cocaine. Therefore it is a powerful addiction to overcome, but once you start to put the good foods into your body in a larger volume than the bad foods, your body will help you make the shift, as cravings will adjust to the new good nutrition.


Dr. Gioffre underscores the importance of balance. He states that the first step toward better health is a changing of one’s diet, but it is equally important to reduce stress as stress can create acid, and finally… it is important to find a way to make the new changes sustainable. He talks about Alkamind, and the many products they provide for people who want to take charge of their health, and improve their well being. He details how anyone can implement a new nutritional program, and utilize healthy minerals to neutralize acid. He states that the more healthy minerals we can put into our bodies, such as kale and avocados, etc., the better chance we have to neutralize the acid in our body.


Dr. Gioffre talks about his daily and nightly regimens, and how he personally supplements for improvement of health. He discusses the importance of oxygen, and improvement of our breathing. He details the 3-6-5 power breath method, which is essentially breathing in through the nose for 3 seconds, holding it for 6 seconds, and then exhaling out the mouth for 5 seconds. He stresses the importance of doing this every morning to oxygenate, alkalize, and energize our blood. Dr. Gioffre states that hydration is equally important, and that “the solution to pollution is dilution.” Drinking more water is something most everyone needs to do daily. Additionally he describes other important healthy additions to our lives such as particular types of exercise, and he reiterates the critical importance of eating the right foods and letting green goodness, healthy minerals, begin to repair the body.


The successful nutrition advocate talks about his program for good health and some of the people who come to him for specialized input. He discusses the importance of making the transition to good health with an advocate on your side as it is sometimes difficult when the body starts to detoxify—help is a good thing. A support network or person can help people maintain their program and have a better chance for success.


He discusses the pros and cons of the keto diet, and notes how keto is an acid forming diet, and is not sustainable. Thus Dr. Gioffre’s program pulls from the keto diet, only its best elements— the healthy fat component. Avocados, raw nuts and seeds, healthy oils, etc., are all excellent healthy fat elements that anyone can introduce into their daily diet to help achieve optimum health. Good fats are essential, but too much animal protein turns to sugar, and can be acid forming. By combining vegetarian elements and keto, Dr. Gioffre’s program can boost energy, create better health, and help prevent disease. And he triple underscores one critical point, that it is never too late to begin, and that everyone, literally everyone, can find ways to improve their health by making simple changes and working toward their goal.

Bond,Silicon-Carbon Bond – Jennifer Kan, Postdoctoral Researcher at the Division of Chemistry and Chemical Engineering, California Institute of Technology – Engineering Proteins To Do Incredible Things That Have Not Been Seen In Nature

Dec 20, 2018 17:42

Description:

Jennifer Kan, postdoctoral researcher at the Division of Chemistry and Chemical Engineering, California Institute of Technology, provides an overview of the exciting new possibilities that could arise as researchers utilize bacteria to create silicon-carbon bonds.


Kan’s research and interest lies at the intersection of science and engineering. Kan is excited about her work as a postdoctoral scholar in the laboratory of Frances Arnold, the first woman to be awarded the $1.1 million Millennium Technology Prize, for her groundbreaking work on directed evolution. Directed evolution is a process that allows for the creation of desired traits within enzymes. According to scientific findings, silicon and carbon are quite similar in regard to their chemistry, with both maintaining the capability to produce extended chains of molecules, such as DNA and proteins. 


Kan talks about the lab’s work and mission: to engineer proteins to do incredible things that have not been seen in nature. Via directed evolution, researchers have used a bacterium to create a silicon-carbon bond in a natural manner, which previously had only been accomplished synthetically. She states that while silicon is the second most abundant element on our planet, for some reason living organisms have never integrated silicon into their native biochemistry. But in the lab, Kan says it is possible for proteins to activate this chemistry. Interestingly, this groundbreaking discovery may have cleared a path toward integrating computer chips with the human body, though Kan stresses that potential possibility is a long way off in the future, so for now we’ll still have to experience this in Hollywood movies only. 


The researcher and biochemistry expert states that silicon is extremely prevalent in our lives and products and that it is truly the core element that makes modern life possible. Kan discusses the benefits of binding silicon to carbon, and how that bond is crucial for the manufacturing of materials that are necessary in our world. She explains the incredible significance of this new development in science—utilizing biology to make these bonds—and how it can open the door to programming life.


Kan states that scientists must ask the right questions, in regard to biological systems, in order to analyze and discover their potential with respect to chemistry.

The lab’s work could create a seismic shift in how medicine and materials are manufactured and produced. Kan feels that there will be a number of valuable applications for this work, for many reasons, two of which are cost reduction, and the newer process is better for the environment compared to the old way of making silicon bonds.


Kan explains how their work involves creating metabolic pathways, convincing bacteria to use the silicon-containing building blocks to create things that are potentially useful for biology. She discusses the many possible uses for this scientific achievement, notably—the use of bacteria to create silicon-containing drugs. She talks about the incredible environmental benefits and how this process can diminish the need for the use of toxic chemicals. 


The chemistry expert talks about some of the other innovative uses of their silicon bonding work. She outlines the possible molecules that could be experimented with in her lab, and how the introduction of new elements can literally change functionality. Kan details some of the complexities of the chemical processes and elements, and what her lab’s team hopes to find as they dig deeper into the bonding experimentation. Additionally, Kan lays out their schedule and timeline for this new, exciting work, and talks about their latest publishing and interesting findings. Now that they can actually see what is happening within the proteins, Kan hopes that soon they will be able to complete the story so to speak, and more fully understand how silicon bonds can be made in proteins. 

Quantum Questions – Murray Thom, Director of Software and Cloud Services at D-Wave Systems – How Quantum Computing Holds the Potential To Provide Answers To Many of the World’s Complex Problems

Dec 19, 2018 38:32

Description:

Murray Thom, director of software and cloud services at D-Wave Systems, The Quantum Computing Company (<a href="http://dwavesys.com">dwavesys.com</a>), delivers a thorough overview of quantum computing and its many uses.


Thom is a seasoned professional in the technology and computing arena. He is heavily involved in multiple areas that are key to D-Wave’s operations, and success. Thom plays an instrumental role in the R&amp;D at D-Wave, including design and manufacture of crucial components and elements. Additionally he provides important technical support to the sales team that relates to his in-depth knowledge of applications, algorithms, and more.


D-Wave Systems is the first quantum computing company and they are continually striving to make rapid advancements in the computing space. Notably, D-Wave recently released its 1000+ qubit D-Wave 2X system. And the impressive system was installed at the NASA/Google Quantum Artificial Intelligence Lab, Los Alamos National Laboratory, and Lockheed Martin. The dramatic results from Google on the D-Wave 2X showed a 100,000,000 times speed increase over a traditional system for specific types of problems.


Thom talks about D-Wave’s mission: to unlock the power of quantum computers for real world solutions. He states that for nearly 20 years the company has been building quantum computers and servicing the clients, users, and developers who need them. Thom discusses some of their collaborative work with clients and customers over the past decade that has led to great advances and early applications for their quantum computing systems. He details some of their specific client projects, such as their work with Volkswagen on traffic flow optimization.


D-Wave’s quantum computer utilizes quantum dynamics to accelerate and create innovative methods for solving optimization, material science, sampling, and machine learning problems and issues. Through a process known as ‘quantum annealing’ it stimulates the tendency of real-world quantum systems to access new low-energy states. To consider optimization in terms of high and low points within a landscape, every coordinate represents a potential solution and the elevation represents its energy. And the optimum solution is the one with the lowest energy that corresponds to the lowest point across the landscape.


Thom outlines how quantum computers are different. A traditional computer stores information as ‘bits’ with assigned values of either 1 or 0. A quantum computer works with information that is preserved in quantum bits, known simply as qubits. And a qubit can hold a value of 1 or 0, essentially any quantum superposition of these two represented states. This is how quantum computers can process enormous volumes of information so easily. Quantum memory has incredibly impressive capacity. Though it seems small, it can store a tremendous amount of information, which enables users to search massive solution areas and find answers fast. Thom details D-Wave’s exciting project known as Leap, which is an environment for developers to literally build and operate their own specific quantum applications. Leap is cloud-based, and as such it provides real-time access to an operational quantum computer. Developers and researchers are provided the opportunity to work with open-source tools, and are given access to interactive demos, coding examples, and detailed information articles. Leap provides an open pathway to incredible collaboration within the active online community.


Thom cites specific examples of how quantum computing solutions impact advertising buys and budgets, and overall optimization, and the decision-making process of business leaders with respect to their advertising and marketing. From providing hotel recommendations to travelers, to optimization of workflow in factories, Thom discusses the numerous ways that quantum computing is changing how businesses operate.


Conventional systems are inept in many ways and quantum computing is stepping up to provide more advanced problem-solving assistance. Quantum computing provides the potential to solve many complex and extremely technical, scientific, defense, and commercial problems and Thom expects that it will deliver results in a myriad of industries and areas.

Sick and Tired of Being Sick and Tired—Steven Y. Park, MD and Author—Sleep, Interrupted: A Physician Reveals the #1 Reason Why So Many of Us are Sick and Tired

Dec 19, 2018 35:50

Description:

As an ear, nose, and throat surgeon, Dr. Steven Y. Park sees many patients with chronic issues, but it wasn’t until he started ordering sleep tests that he discovered many of these patients were also suffering from sleep apnea. Since then, he’s continued to collect data on the connection between sleep issues and chronic ENT conditions, high blood pressure, anxiety, diabetes, and digestive problems.


According to Dr. Park, breathing problems can be brought on by and contribute to a variety of factors, many of which could help us better understand, manage and treat common illnesses. He joins the podcast to discuss variations of apnea, how exactly it’s diagnosed, what happens physiologically during episodes of apnea, upper airway resistance syndrome (UARS), fragmented sleep that involves restless legs and teeth grinding, how simple snoring can lead to apnea, and tips for handling different levels and types of sleep disturbances.


Tune in and check out his book Sleep, Interrupted: A Physician Reveals the #1 Reason Why So Many of us are Sick and Tired for more. 

The Latest News and Advice from The Ultimate Expert on Sleep—Michael Breus, PhD— The Sleep Doctor and Author of The Power of When

Dec 19, 2018 31:11

Description:

Michael Breus, PhD Clinical Psychologist, Diplomate of the American Board of Sleep Medicine, Fellow of the American Academy of Sleep Medicine, author of several books on sleep disorders, and regular guest on The Dr. Oz Show joins the podcast to discuss the latest in what nearly half of the country has some sort of struggle with<span data-mce-type="bookmark" style="display: inline-block; width: 0px; overflow: hidden; line-height: 0;" class="mce_SELRES_start"></span> sleep. He fell in love with clinical sleep medicine just a couple days into the rotation during his medical residency and has since been established as what many would call the ultimate sleep expert.


There are three major areas at the forefront of current research on sleep medicine: the connection between sleep and cannabis, the connection between sleep and the gut microbiome, and the relationship between sleep and school-aged children. Dr. Breus touches on each one, as well as a range of other topics, including the role of genetic chronotypes in sleep, five steps to getting the best sleep, and why a high-carb snack before bed might actually benefit you.


Interested in hearing more? Press play and visit <a href="http://thesleepdoctor.com">thesleepdoctor.com</a> for a range of articles on a variety of topics on sleep. 

Sports Betting Reinvented – Mark Thomas, Co-founder and CEO of ZenSports – The Exciting Technology Behind Groundbreaking New Sports Betting Platforms, Sports and Cryptocurrency Together at Last!

Dec 15, 2018 26:58

Description:

Mark Thomas, co-founder and CEO of ZenSports (zensports.com), provides a detailed overview of their groundbreaking new sports betting platform.


Thomas is a savvy technology entrepreneur and the enthusiastic CEO of ZenSports, an exciting new peer-to-peer, decentralized sports betting marketplace that utilizes modern cryptocurrencies and blockchain. Thomas has extensive experience in the tech space, notably as an original co-founder and CEO of Reesio, a top venture-backed startup in real estate technology that was successfully launched then subsequently acquired by News Corp's Realtor.com. Additionally, Thomas founded Thomas Executive Resources, a recruiting agency that flourished, which he later sold in 2008. Thomas currently owns and operates a diverse real estate investment company as well: Mark Thomas Realty Holdings. Self described as a serial entrepreneur, Thomas is passionate about startups, tech, investing, and real estate.

He brings many skills to the table as CEO of ZenSports, including executive leadership and business development, marketing, product management, recruiting, and finance. He has successfully worked with many venture capitalists and angel investors and is well versed in strategic planning. 


Thomas discusses his background and motivation for entering the blockchain and cryptocurrency arena. His interest in advancing tech, and sports, pushed him to launch ZenSports, which as he describes was a meetup recreational sports app in which users could meet and play sports for money. As Thomas became more interested in the expanding cryptocurrency market, and he began investing, he was intrigued and wanted to dive deeper into the emerging digital financial and blockchain space. He saw a way to weed out the middlemen through decentralization in the sports industry. Thomas decided to utilize blockchain to create a better world within the sports industry, one that was more open to everyone. They set out to develop a better sports betting product utilizing blockchain and cryptocurrency to weed out the middlemen and bookmakers and keep it focused on users and the action. The platform puts betters in control of their action, in control of the bets they want to place, directly and immediately. ZenSports offers peer-to-peer sports betting in an active marketplace in which anyone can create and accept sports bets with anyone else in the entire world, with bookmakers no longer needed or necessary.



The technology guru details the workings of their platform—how the system functions and operates. As he explains, users of the platform can input the kind of bet they want to place and the platform will match them up with those in the network who are willing to take that bet. When a match is made, the platform will lock them into a contract so the bet is secured and official, so neither side can back out of the bet, etc. Additionally, makers of the bets are responsible for submitting the results of the bets. Their system involves a created token economy that can sit a small escrow fee aside, and in case the results submitted are incorrect, the taker of the bet can dispute those results. Disputes are settled in the marketplace as all other betters vote on what the actual outcome was. Thus the majority of the marketplace votes on the correct result, keeping the bets accurate and efficiently managing the system. 


Thomas talks about the other betting platforms in the market. He states that what sets ZenSports apart from the pack is that they are truly focused on traditional sports betting, their platform is 100% peer-to-peer, and their system is completely decentralized via the use of cryptocurrency and blockchain. While other competitors are doing some of these things, no one else is really mastering all three the way ZenSports has, which gives them a competitive edge and opens their platform up to more action in the biggest market of all. 


The sports betting aficionado gets specific about their platform’s details and the minutiae of how users can configure it to really work for them in an exciting way. He states that in the truest sense, ZenSports is really a matchmaker, matching people who have similar interests in sports betting who want to bet and enjoy the process. Thomas talks about some of the new developments that are on the horizon for ZenSports. He says they are working on their cryptocurrency token, to streamline transactions and keep it simple to use. Additionally, they are adding more and more sports and leagues to their app, as well as new features nearly weekly. Thomas states that they are constantly doing user testing so the product they deliver is not only thoroughly enjoyable but also top of the line and tested for success and precision. Easy and fun is what it is all about, and Thomas is pleased to bring the ZenSports platform to sports lovers everywhere. 

Cellular Discoveries – Dr. Rosalyn Abbott, Assistant Professor of Biomedical Engineering at Carnegie Mellon University – The Important Research in Cell and Tissue Engineering That Could Lead to a Better Understanding of Disease Pathways

Dec 14, 2018 29:52

Description:

Dr. Rosalyn Abbott, assistant professor of biomedical engineering at Carnegie Mellon University, provides an insightful overview of her research into cell and tissue engineering and the potential for diagnostic and therapeutic breakthroughs. 


As a Ph.D. in bioengineering, Dr. Abbott has a keen interest in cell and tissue engineering, biomaterials, adipose microenvironments, disease modeling, and tissue regeneration. In her Carnegie Mellon lab, human adipose microenvironments are developed and tested for responsiveness to stimuli hypothesized to alter disease mechanisms, for example, the transition of obese tissues to insulin resistant type II diabetic tissues; metabolic behavior; and therapeutic potential. Dr. Abbott and her skilled team of researchers focus on integrating biomaterials with tissue engineering techniques and perfusion bioreactors. Interestingly, silk is used as an organic biomaterial to aid long-term culture of adipose microenvironments in vitro. The team’s long-term goal is to use these selected adipose tissue systems to inform preventative as well as therapeutic measures for patients who are affected by the metabolic syndrome. Dr. Abbott’s lab is particularly interested in the utilization of tissue engineering to study metabolic dysregulation during the complicated transition of obesity into insulin resistant type II diabetes. 


In addition to running her lab and being an assistant professor in biomedical engineering with an additional appointment in materials science and engineering, Dr. Abbott has been an active member of many important research and academic environments. She received her BS and MS degrees in biomedical engineering from Rensselaer Polytechnic Institute. And her PhD in bioengineering was achieved at the University of Vermont. Additionally, she was a postdoctoral fellow in the biomedical engineering department at Tufts University, where she gained recognition for her work in the development of adipose tissue engineered models. 


Dr. Abbott discusses her lab’s history, and work—engineering fat. She talks about the major challenge of designing drug therapeutics, which is the fact that our basic understanding of human disease mechanisms is based on animal models or simplified cell culture models. She informs us that fat, or adipose tissue, has long been thought of as a passive organ with the sole purposes of storing energy or insulating the body, but recent research has discovered that fat plays a more dynamic role in the body in regard to disease. Specifically, fat communicates with other tissues, and obesity is a chronic state of inflammation that causes stress on the rest of the body. 


The bioengineering PhD talks about chemicals that affect the body, such as those we ingest from packaging, etc. She discusses the impact of bisphenol S, commonly known as BPS, that we take into the body when using containers for drinks and food made from some plastics. She recounts some experimental evidence that was revealed by testing exposure to certain chemicals, and how it related to accumulation of additional adipose tissue. 


Dr. Abbott discusses the process of lipolysis, and specific proteins. Lipolysis is the breakdown of lipids and it involves the hydrolysis of triglycerides into glycerol and free fatty acids. The process occurs in adipose tissue and lipolysis is the means to mobilize stored energy during periods of fasting or exercise. She states that adipocytes (cells that are specialized for the storage of fat that are found in connective tissue) can last for up to ten years in the body, so the rate of turnover is dramatically slow indeed. She explains how adipocytes communicate with each other, and gives an overview of some of the other cells in the system. She discusses adipose-derived stem cells that are often located near the stromal vascular fraction, a heterogeneous collection of cells that are contained within adipose tissue.


The PhD talks about the work her lab engages in to understand the transition of obesity into insulin resistant type II diabetes. They seek to understand how this expansion in adipose tissue relates to larger systemic changes within the body, and how it all affects other diseases. Their question is what is being communicated that is causing all these detrimental problems within the body, and Dr. Abbott hopes to find more answers that will lead to solutions and treatments by understanding fully the pathways to certain diseases. Additionally, she is hopeful that their research will also lead to better drugs for treatment. As their mission states, there is a crucial need for monitoring physiologically relevant, sustainable, human tissues in vitro in order to better understand the development and causes of metabolic diseases. 

Dental Diligence – Dr. Timothy Chase, NY Cosmetic Dentist – Modern Dentistry, Oral Health, Bacteria, Disease, Proper Care and Treatment

Dec 14, 2018 26:02

Description:

Dr. Timothy Chase, NY cosmetic dentist, delivers a detailed overview of modern dentistry, oral health, and good home practices we can all benefit from.


Dr. Chase has over 25 years of experience in cosmetic and restorative dental treatments. He specializes in natural tooth preservation and oral health. He is celebrated for his unique ability to provide dental work that looks natural and organic, not overdone or clearly ‘worked on.’ Dr. Chase’s dental office, SmilesNY, has been featured in numerous magazines and on popular TV programs. At SmilesNY, Dr. Chase works with his patients to restore both the aesthetic appearance and functionality of their bright smiles. He provides a myriad of treatments, services, and procedures such as porcelain veneers, teeth whitening, smile makeovers, dental bonding and contouring, and the popular, Cosmalite. He is skilled in all types of restorative treatments including inlays and onlays, implants, bridges, dental fillings, metal-free porcelain crowns, and even full mouth restorations.


Dr. Chase earned a Doctor of Dental Medicine (DMD) from the Boston University School of Dental Medicine, and he completed his general practice residency at Columbia Presbyterian Medical Center and the Veterans Administration Hospital. His innovative work has made him one of the top cosmetic dentists in New York.


Dr. Chase discusses his practice and unique approach. He details the many ways that oral health is overall health, in that what happens in the mouth can impact the entire body. He stresses the importance of taking care of teeth and gums and making regular appointments for care. Specifically, he discusses the various diseases that can arise and the treatments and procedures that can be implemented to combat them. He states that bleeding gums, when we brush or floss, can be an indicator that something is going on, for it is not natural for bleeding to occur. Additionally, he says that sensitivity issues to cold, etc. are a possible indicator, and should be considered for further review. Odors and bad breath are also indicators that perhaps one should schedule an appointment right away, or simply increase the regularity of their appointment scheduling.


The cosmetic dentist provides an overview of the technical aspects of reviewing teeth, specifically x-rays and a newer process called transillumination. A dental transillumination test can reveal problems in teeth that could be difficult or impossible to see with the naked eye or even with x-rays. Decay will appear in the image as cloudy shadows. Healthy tooth structure will appear lighter, because light shines through it more easily. A dental transillumination might also expose fine cracks within the teeth. He explains how some of the newer viewing options provide greater detail and more accurate information, whereas traditional x-rays may sometimes make it difficult to clearly tell whether something is a cavity or just a shadow.


Dr. Chase discusses new scientific discoveries that show that bacteria in the mouth varies greatly between people, and how some bacteria is extremely more destructive than other bacteria. He details how some newer mouthwashes can directly impact the flora in the mouth and make it less destructive. He stresses the importance of using mouthwash that contains no alcohol because alcohol dries out the mouth, and can reduce saliva, which is a natural protector of the teeth.


The dental expert answers questions about his particular approach to dentistry. He talks about increasing frequency of visits, and how the increase can help curb potential problems. Additionally, he discusses products such as electric toothbrushes and more advanced mouthwashes. He underscores the importance of brushing for at least two minutes, which may seem like a long time but it is necessary for thorough cleaning. The benefits of electric toothbrushes are many, but some of the top points he discusses are: thoroughness of cleaning and proper time allotment. Dr. Chase points out that electric toothbrushes tend to give their users a better cleaning overall, and some of the models have timers that allow the user to know when it is time to move on to another section of the teeth. Further, he talks about teeth whitening and the products that have been proven to be safe, as well as those products that are questionable in regard to safety.


Dr. Chase served as a clinical instructor at New York University Dental School where he was responsible for the training of undergraduate dental students, as well as doctors from many countries around the world, on the current techniques in restorative dentistry. Dr. Chase is a faculty mentor at Spear Advanced Dental Education Center in Scottsdale, AZ. He is a proud member of The American Dental Society, The American Academy of Cosmetic Dentists, The Academy of General Dentistry, and The Spear Faculty Club.

The Rigor of Regulation–PJ Di Giammarino, CEO of JWG – Keeping Up With Changing Complex Regulation in the New Digital Financial Market

Dec 14, 2018 22:58

Description:

PJ Di Giammarino, CEO of JWG, details the complex and sometimes convoluted topic of regulation, in an ever-increasing digital financial world.


Di Giammarino has over 20 years of experience in new technology designed to solve complex financial services problems and issues. For over a decade Di Giammarino has been the CEO of JWG Group, a prestigious think-tank that is internationally recognized by regulators, financial institutions, and technology firms. Di Giammarino has a vast network of the industry’s leading technology specialists, policy makers, and global market leaders, all of whom he brings together to find solutions to global challenges through intensive collaborative working groups and collectives. Di Giammarino is recognized widely for his work with the MiFID Implementation Group and a wide range of RegTech forums. Prior to founding JWG Di Giammarino worked with Barclays Capital, Booz Allen, and McKinsey. He is a vocal and active member of many advisory groups and organizations including the International Organization for Standardization through the ISO UK committee for financial services, IST/12, and Di Giammarino serves as the Secretary for the FinTech Technical Advisory Group as well.


Di Giammarino talks about his firm and their immersion into RegTech, helping financial services define, understand, comply, and advance. He discusses the importance of bringing banking out of the analog era and into the new digital era and applying regulations and controls to help ensure the safety of transactions and accounts. RegTech, as he explains, pertains to the application of AI and new technologies to the financial sector and businesses in general. Di Giammarino states that banking has become very technical, and regulators have been forced to adjust and become technically savvy themselves, to meet the demands and keep pace with a rapidly changing digital financial sector.


Since 2006, JWG has held 400 working groups to focus on a variety of regulatory topics. He discusses the many action points that have come out of the G20 and others, and how the new changes are creating a glut of work for regulators and financial sector strategists. Di Giammarino talks about JWG’s mission of using technology to apply to the new and voluminous regulatory data, to bring efficiency and streamline the process of adapting to changes. JWG’s team scours the massive bundle of regulatory information and brings it into a manageable initiative that businesses can follow and implement. 


The financial regulations expert delves into the many specific areas of regulation, and the tools companies can utilize to keep up. Transparency, as Di Giammarino states, is the answer to the crisis, as everything has to be on a report. With tighter regulation many more reports are generated on various subjects and areas, from trading activity, to how you know your customer, to money laundering checks, to how to manage capital and potential exposures. By defining more accurate language and standards, compliance is easier to implement and maintain. JWG’s team of independent analysts assists senior executives within public and private sectors to determine how regulations can be implemented in the correct way. Essentially, their skilled analysts and technology leaders help financial services take control of global regulatory change by implementing a technology-enabled standardized approach.


Di Giammarino talks about how regulators across the globe are now communicating and sharing ideas, for the greater good of security for everyone. He states that the role of new technology is not really firm-by-firm, but is actually theme-by-theme. Continuing, he lays out the idea that whereas some regulators have an appetite to automate their rulebook, others are more focused on using blockchain to manage the problem of money laundering, thus the areas of interest and focus are varied. 


Lastly, Di Giammarino discusses fear and greed, as the motivators of regulation. Regarding fear, the sheer volume of regulations has grown to the point that many businesses are afraid that they may be missing things that are critical. In terms of greed, the costs are often excessive, with a large amount of manual effort needed. Di Giammarino details the many ways that his team can facilitate the processes for security, data loss control, and management, etc. through the use of AI and technology. 


Di Giammarino has been a consistent author and international public speaker for more than two decades on the role of new technologies for the financial services infrastructure.

The Perfect Pet Diet – Dr. Natasha Lilly, DVM, CVA, Animal Diet Expert And founder of the Royal Animal Health University – Pet Nutrition, Balanced Diets, and Improved Health for Wellness and Longevity

Dec 12, 2018 24:59

Description:

Dr. Natasha Lilly, DVM, CVA, animal diet expert and founder of the Royal Animal Health University (<a href="http://royalanimalhealthuniversity.com">royalanimalhealthuniversity.com</a>), delivers an interesting overview of pet nutrition and the importance of a well balanced diet for our furry friends.


Dr. Lilly has a profound passion for animal well being and care. She attended California Polytechnic State University on the pre-veterinary track studying animal science, and completed her DVM work at UC Davis with a concentration in equine medicine. Dr. Lilly has extensive experience in equine sports medicine and animal acupuncture. Frustrated by traditional methods of treatment, Dr. Lilly sought new ways to provide care. She began working for an established acupuncturist and complementary medicine DVM in Chicago—Dr. Barbara Royal. Dr. Royal’s approach to animal health combined conventional and holistic medicine practices. Holistic veterinary medicine is a branch of veterinary medicine that implements alternative medicine in the treatment of animals that strongly stresses the importance of empathy and very minimal invasiveness. Dr. Lilly worked at Central Coast Pet Hospital and Emergency, where she practiced acupuncture services. She has knowledge and training in Chinese herbal medicine through the Chi Institute.


Dr. Lilly discusses their diet software for dogs and cats. Based on the groundbreaking work and diet analysis of Steve Brown, Dr. Barbara Royal and Dr. Natasha Lilly have incorporated his unique Animal Diet Formulator into their care plan. (Steve Brown is a revered nutritional researcher and formulator of the first commercially available fresh-raw pet food in the United States.)


The animal diet expert talks about the kinds of foods people feed their pets, and surprisingly, home-prepared food is often the worst because it is extremely out of balance for the pet’s nutritional needs. Though with recalls and commercial pet food problems, she came to the conclusion that home-prepared food could be balanced and healthy… if pet parents could learn how to balance it for maximum nutritional benefit. She discusses the importance of considering the biology and physical traits of the species in regard to their optimum nutritional intake.


Dr. Lilly details how their formulator works, and how it can be set up to comply with American or European guidelines. She discusses how her team at the Royal Animal Health University works with clients to educate them on the software, so they get a comprehensive understanding of what it offers and how to utilize it.


The animal care educator discusses their website and the benefits that it offers to pet owners. She talks about some of the problems with animal diets, and mistakes some pet owners make when attempting to feed their pets. She elaborates on animal diets, and how it is important to incorporate things that many of us don’t eat, such as spleens, livers, kidneys, etc., because our pets are biologically designed to eat whole animals. And animals enjoy this type of organ meat and it is natural for them. Additionally, she discusses how smell is a factor in pet food, and the ways that smell can be enhanced to entice your pet to eat their food. She talks about the ways pet owners can add butter, or lightly sear the food, to enhance the meal and get pets excited to eat.


Dr. Lilly discusses weight issues with pets and the importance of getting weight under control to avoid heath issues. Additionally she discusses some of the absolutely unacceptable foods for dogs and cats; she stresses that pets should never be fed chocolate, onions, or grapes. When formulating fresh foods, Dr. Lilly states that carbohydrates can be lowered, which makes a big difference in pet diets. She also states that all carbs are not created equal, and some sources for carbs are far better than others.


Dr. Lilly describes their upcoming commercial software that provides a wide variety (over 1500 ingredients) for commercial companies who want to utilize the formulation software when preparing pet food brands for market. She discusses individual recipes as well, and consulting services for pet owners whose pets have specific conditions. Dr. Lilly is passionate about pet health and the Royal Animal Health University is steadfastly dedicated to a holistic, common sense approach to contemporary animal care.

Sleep Apnea Solution – Robert S. Rosenberg, D.O., FCCP, Sleep Medicine and Sleep Apnea Specialist – Sleeping Better – Sleep Solutions for Healthier Sleep, Combating Sleep Apnea, and CPAP Device and Care

Dec 12, 2018 38:53

Description:

Robert S. Rosenberg, D.O., FCCP, sleep medicine and sleep apnea specialist, discusses sleep apnea, CPAP compliance, and CPAP care.


Robert S. Rosenberg, D.O., FCCP, has more than three decades of experience in sleep medicine. Dr. Rosenberg is board certified in sleep medicine, pulmonary medicine, and internal medicine. He has served as the medical director of the Sleep Disorders Center in Prescott Valley, Arizona, as well as the sleep medicine consultant for Mountain Heart Health Services in Flagstaff, Arizona. Dr. Rosenberg is a sought-after speaker on the subject of sleep and other medical topics and is a regular guest at medical conventions. He is a published author and columnist whose work has appeared in many top periodicals such as O, The Oprah Magazine, Women’s Health, Prevention, Woman’s World, Parenting, and Ladies’ Home Journal, as well as many others. His books Sleep Soundly Every Night, Feel Fantastic Every Day, and The Doctor’s Guide to Sleep Solutions for Stress & Anxiety are in wide release and are considered by many to be must-reads for doctors and patients alike. 


The sleep expert discusses sleep apnea and the solutions to the problem. As he states, obstructive sleep apnea, the most common form of sleep apnea, is when your airway basically collapses during sleep. So for those who are predisposed to sleep apnea either due to obesity, large tongues, heredity, etc., the problem could exist. Dr. Rosenberg mentions that of the nearly twenty million with sleep apnea, only about twenty percent of those have been diagnosed. And with sleep apnea, the oxygen drops, carbon dioxide levels rise, and the sympathetic nervous system (known as fight or flight) is triggered which constricts blood vessels and increases blood pressure. This unfortunate chain of events puts extra strain on the heart, brain, and other areas of the body. He delves into a detailed analysis of the areas of the body that could be affected by obstructive sleep apnea and the ways it can be prevented or treated. 


Dr. Rosenberg’s opinions and findings on the subject of sleep have made him a frequent guest on television and radio shows. Additionally, he publishes a monthly newsletter for healthcare professionals that condenses the most current research in sleep medicine, as well as an informative monthly newsletter on a myriad of sleep topics for the general public. Dr. Rosenberg is an affiliated professor of sleep medicine at Midwestern College of Osteopathic Medicine and he is on the board of directors for the American Sleep Association. In this discussion, Dr. Rosenberg details the health problems that sleep apnea can contribute to, and how sleep apnea is highly underdiagnosed. 


The sleep doctor talks about the new CPAP offerings on the market and their benefits. CPAP stands for Continuous Positive Airway Pressure. CPAP is a positive airway pressure ventilator that applies mild air pressure on a continuous basis to keep airways open in people who have difficulty breathing spontaneously on their own. As he states, the new offerings are smaller and quieter, and many people find that they are much more comfortable than the large cumbersome devices of the recent past. He discusses how the pressure is variable and changes based on a person’s specific requirements. He also talks about the various ways someone can delay the functioning of the device if they want to fall asleep without it intruding on them, and then it will begin after they have had time to begin resting. Additionally, he talks about the heated tubing that new systems offer to help prevent dryness, providing quality moisture into the air. 


Dr. Rosenberg discusses maintenance of the machines and systems and hoses. He talks about the benefits of the SoClean sanitizing product. SoClean is an efficient and effective way to clean CPAP machine equipment. The SoClean system kills 99.9% of CPAP germs and bacteria in the mask, hose, and reservoir and does not require disassembly or chemicals.


The sleep health expert details oral appliances, which are devices designed to adjust the jaw, bringing the lower jaw forward which in turn brings the tongue forward, and in many cases, this is enough to prevent some people’s problem of sleep apnea. Oral appliances are designed specifically for individuals. Dentists will make molds of their patients’ upper and lower teeth in order to tailor the oral appliance for individuals. The oral appliances are adjustable, worn at night, and for many people, this specially crafted device is a great option to prevent sleep apnea and avoid CPAP. 


Additionally, Dr. Rosenberg discusses some of the patients he sees, and their stories of past frustration with their care and devices. Dr. Rosenberg’s goal is to find ways for these patients to be healthy and enjoy their sleep, with whatever device or system or method is necessary, and he works with people individually to ensure they get the best quality care.

The Pyramid of Health – Dr. Thomas O’Bryan, DC, CCN, DACBN, and Author of You Can Fix Your Brain – Rethinking Our Approach To Solving Common Medical Problems

Dec 11, 2018 50:04

Description:

Dr. Thomas O’Bryan, DC, CCN, DACBN, and author of You Can Fix Your Brain: Just 1 Hour a Week to the Best Memory, Productivity, and Sleep You've Ever Had, provides a scintillating overview of the mind to body connection and how we must sometimes question conventional medical wisdom in order to find real solutions. 


Dr. O’Bryan has spent his life focused on promoting good health for everyone. He is an internationally recognized, celebrated keynote speaker who covers important topics such as food sensitivity, environmental toxins, the development of autoimmune diseases, and wellness. Dr. O’Bryan works with patients to understand their history and make changes that will improve health. His intriguing docuseries, Betrayal: The Autoimmune Disease Solution They’re Not Telling You is an investigatory series that delves into why our immune systems attack our own tissue (autoimmunity). The successful, critically acclaimed series has garnered much attention and has been viewed by many people from all walks of life as individuals struggle to find answers in a complex medical world.  


Dr. O’Bryan talks about his early medical education back in the 70s, and the influences on his life that pushed him toward his career goals. He discusses his first introduction to neurological switching and the ways that electromagnetic pollution can affect the brain and nervous system. He recounts his experiences with acupuncture, which he refers to as early AI, and what acupuncture points can reveal regarding overall health. He tells stories of specific patients who experienced remarkable discoveries that greatly impacted his medical path. 


Dr. O’Bryan discusses the four categories of health that he describes as a pyramid of health. He describes the pyramid’s base, which is comprised of the basic structure such as chiropractic, pillows, massage, how we sit, how our shoes wear down, etc. He discusses the other sides, such as biochemistry, which is essentially what we eat, what we breathe, the drugs we take, etc.; the emotional/spiritual; and the electromagnetic. Dr. O’Bryan states that every medical problem needs to be looked at through all these lenses, to fully understand it, and to solve it. Interestingly, he says that difficult-to-solve medical problems are often connected to the emotional or spiritual realm. He cites specific examples of patients who have done their best to take actions to get healthy, but sometimes the emergency brake, as he describes it, is on, meaning underlying electromagnetic pollution or emotional issues could be blocking the path to good health. 


The mind to body connection expert discusses paradigm shifts. He states that while the United States is annually, without fail, ranked either number one or two in the world for leading health technology, that the US is also ranked in the bottom five out of 58 industrialized countries in healthcare effectiveness. Thus, as he states, our healthcare system doesn’t work. He stresses the importance of challenging the prevailing dogma, to question the things we were taught to believe about healthcare. With a prepared mind, and tenacity, Dr. O’Bryan states that we can all challenge conventional wisdom and find new avenues to improve our health. Dr. O’Bryan’s book, You Can Fix Your Brain: Just 1 Hour a Week to the Best Memory, Productivity, and Sleep You've Ever Had speaks to this very issue. To those who are concerned about any type of brain ailment or issue, ranging from chronic conditions to the more common, brain fog, or perhaps brain fatigue, the book outlines a path to combating specific issues through prevention as well as treatment. Regardless of the brain issues, one is dealing with, for most issues, Dr. O’Bryan’s book provides a plan that can make a difference in brain clarity, vitality, and energy. The methods provide a process to improve memory, decrease fogginess and exhaustion, etc. It’s an overall guide to improving a cognitive function that helps the reader to consider what they eat, what’s in the environment, and how to take better care of themselves, and it only requires about one hour a week to begin seeing improvements that could be drastic after six months of regular work.


Dr. O’Bryan recounts his connection with celebrity actor and comedian, Fran Drescher, author of Cancer Schmancer. He discusses her work and commitment to the cause of helping people find a path to better health and how it overlaps with his own personal work in the field. He states that they both agree that in regard to health problems, you must always consider the big picture in order to find your way to a solution. Dr. O’Bryan states that once you identify which side of the ‘pyramid’ you need to explore in order to address your health issue, then you determine which biomarkers you need to check, to find out where your imbalances may be. And he stresses the importance of taking whatever drugs you need for your current issue, but that it is critically important to also dig deeper into how you got there, to find the underlying issue or issues. We must discover what happened, what created the dysfunction originally, to get to the source of the problem.


Smart Work Environments – Saagar Govil, CEO of Cemtrex – Rethinking the Way We Work, from Workstations to Technology

Dec 11, 2018 20:00

Description:

Saagar Govil, CEO of Cemtrex (<a href="http://cemtrex.com">cemtrex.com</a>), discusses the way we work, how we work, and the innovative technology-oriented products that his company develops that will revolutionize our work environments. 


Govil is an experienced business professional and has led the Cemtrex team as its CEO and president since 2011. He was recently honored by Business Insider, ranked seventeenth in their prestigious list: “Top 100 of Silicon Alley.” Additionally, Govil was named to Stony Brook University’s, “Top 40 Under 40.” Govil has a long history with Cemtrex, having previously served as their vice president of operations, where he was responsible for sales and marketing, production, as well as engineering. Govil has extensive experience as an applications engineer adept with individualized customer support on-site, and the design of ready to go engineered systems for a wide variety of projects. He holds a B.E. in Materials Engineering from Stony Brook University, NY.


Govil discusses the history of Cemtrex as a technology company active in the industry for more than two decades, and he outlines the kinds of clients to which they typically provide technology support. He talks about some of their innovative IoT products such as the Cemtrex SmartDesk, which is an advanced workstation that combines all the needs of the modern office into an intuitive sit/stand desk. Govil states that most people have seen incredible innovation come to their computers and personal devices, etc., but that nothing has changed for decades in regard to the office desk and our general workspace. Their groundbreaking product offers 72” of touchscreen, a stark gesture system that allows for touch and touchless gestures to assist workflow, a wireless phone charger, seamless document scanner, built-in keyboard and trackpad, a high-performance PC, integrated phones, and more. Govil explains how touchscreens accelerate workflow and increase interaction efficiency. And as we’ve seen in big budget Hollywood science fiction movies, it is now possible to utilize gesture controls by simply waving your hand in the air—Cemtrex has brought the future to our fingertips. He outlines the intricate details of how the technology works with their top of the line Windows environment and explains how SmartDesk users can configure their workflow with the Cloud, which increases efficiency and decreases clutter. 


Cemtrex is a diversified technology company that seeks to continually drive innovation in a vast range of sectors, from smart technology to virtual and augmented realities, and beyond. Govil’s team’s mission is to introduce technology that will bring real value to people’s lives. Cemtrex, as Govil explains, continually looks for the greatest, brightest new technologies to integrate into their products.


Govil talks about the rollout of their products and the many backorders they are filling as the release begins. Their immersive experience maximizes productivity and Govil is excited about the benefits their integrated technology will bring to individuals, making the work day more efficient, and easier. 


Govil talks about some of the early feedback he has received and potential changes that could come in future versions of their products. As the interest in their product has been intense, Govil expects to see more and more companies coming forward to revolutionize the way their workforce works. With a stated goal of helping people work smarter, and helping manufacturers streamline operations, Govil and his team at Cemtrex hope to bring new levels of intelligence and security to the modern business world, through their value-added, innovative technology-oriented products.

Biotechnology Boost – Matt Lipscomb, PhD, Founder and CEO of DMC Limited – Understanding the Biotechnology Industry, from Processes to Products

Dec 10, 2018 18:19

Description:

Matt Lipscomb, Ph.D., founder, and CEO of DMC Limited (<a href="http://dmcbio.com">dmcbio.com</a>) delivers a thorough overview of the current state of industrial biotechnology.


Dr. Lipscomb is a veteran of the industrial and pharmaceutical biotechnology field. He has experience working in a range of development stages from early R&D to commercial deployment, in many areas. Some notable past experience includes his tenure with OPX Biotechnologies, where he was a founding employee and served in various roles providing technical leadership and facilitating capital raises in excess of $60M. Dr. Lipscomb was highly respected for his leadership in the execution of a successful DOE (Department of Energy) ARPA-E Electrofuels program for the production of biodiesel from H2 and CO2. Dr. Lipscomb has ample technical expertise in multiple areas of research and production including process development and process modeling, microbial fermentation, technoeconomic analysis (TEA) of bio-based processes, and analytical chemistry.


Dr. Lipscomb provides some background on the genesis of DMC as a spinoff from Duke University, where the core technology was first developed by fellow DMC founder, Mike Lynch, MD, PhD. Dr. Lipscomb discusses the recent history of industrial biotechnology, including the technical challenges and barriers. He outlines how DMC’s technology was designed to help bring down costs, to circumvent barriers to development. By bringing down costs during every phase of a project, from inception to delivery of commercially relevant metrics, DMC facilitates the development of multiple specialty chemical products. Essentially, as Dr. Lipscomb states, deployment of their Dynamic Metabolic Control technology significantly reduces the cost and development timeline.


The biotechnology expert details specifics of the industry. As he explains, there are petroleum derivative products, which include the bulk of common products we use, and then there is another class of products made from methods such as fermentation or extraction from plant materials. He discusses the structural complexities, and cites specific examples of how some products are developed. Dr. Lipscomb delves into the chemical and economic modeling that DMC can provide, assisting product developers to bring their products to market more efficiently, and at reduced cost to the manufacturer. 


Dr. Lipscomb details some of the bacterial processes, including a discussion of the various feedstocks used, etc. for development. He outlines the fermentation process and how the end result/product is derived. And he explains why certain processes are more challenging, discussing yield, volume, microbes, applications, cost, etc., with the ultimate issue being price point in the market. For as Dr. Lipscomb explains, the product must be delivered at a price point that is sustainable in the marketplace. 


The DMC cofounder talks about some of the exciting new products that are coming to market. As he explains, one of the advantages of the DMC technology is that they can be very precise in what they create. And in regard to their value proposition, DMC seeks to develop products in a directed fashion, making things that other companies have difficulty developing, and in an economically efficient manner. DMC’s extremely low cost development will make metabolic engineering efforts accessible to everyone, and will create many new commercially viable bioprocesses and deliver sustainable routes to brand new products, as well as existing ones. 

Cognition Ignition – Andrej Nikonov, CEO at Cognostics AG – Advancements in Learning Methodology Via Machine Learning, AI Strategies and Tools

Dec 10, 2018 21:03

Description:

Andrej Nikonov, CEO at Cognostics AG (<a href="http://cognostics.de">cognostics.de</a>), discusses the science of thinking and the many ways AI can expand human knowledge and capability.


Andrej Nikonov, as CEO, is driven to discover new ways to apply physics and mathematics to real-world problems. Nikonov has a particular interest in stochastic processes and differential equations, evolving networks, and network theory-based models of physical systems. Regarding stochastic processes, in probability theory and other related fields, a stochastic process is a mathematical object typically defined as a collection of random variables.


Nikonov earned a bachelor's (equivalent) in physics from Universität Hamburg and a master's degree in applied mathematics and theoretical physics from University of Cambridge. Nikonov continued his advanced studies of physics and mathematics at Ludwig-Maximilians Universität München.


Nikonov discusses the ways his company combines technologies, cognitive sciences, and artificial intelligence. Essentially, Cognostics is the science of thinking. Nikonov states that we live in an age of exploding complexity with change happening at an ever-increasing pace. Nikonov stresses that their goal is not to replace human thinking but to evolve it further. Nikonov’s company, Cognostics’ primary goal is to expand the limits of human thought. Cognostics seeks to create products and develop technologies that will enhance human cognitive ability and the human experience.


Nikonov talks about the areas in which they are highly involved, such as healthcare, education/universities, finance, government democracy, etc. He discusses their thorough e-learning environments that assist many businesses and entities to create AI-supported learning. He cites examples of how the system works within the healthcare space, giving an overview of patient diagnostics, communication, and how learning is applied in regard to patient treatment success and options. And he explains how doctors interact with their systems and tools. 


Cognostics offers multiple products. Their Atlas product offers a unique approach that integrates advancements in learning methodology with the most current machine learning capabilities to create an abundant, interactive and intelligently structured specific knowledge space. Its machine intelligence proactively and freely seeks out developing areas of knowledge from the public as well as private sources. And Atlas exhaustively researches valued publications and databases or the open web to regularly update its knowledge graph.


Their Logos product delivers businesses, governments, and NGOs an opportunity to make more thoroughly sound decisions. The Cognostics structure pulls from decades of viable neuroscientific research regarding how the brain copes with complexity, to get to the root of problem-solving and to develop a visual reasoning architecture that can enhance basic thinking skills, assisting users to make better, meaningful decisions. Through the use of machine intelligence, the Logos suite of cognitive tools can significantly enhance the depth with which even the most diverse and complex issues can be examined cognitively.


Nikonov provides some insight into the new areas that Cognostics has branched into and hopes to further develop, from private projects to projects developed in tandem with the German government. From allocation of resources to long-term planning, the Cognostics’ system can provide many ways to assist companies and organizations with their growth and structure via the use of tools and technologies. Additionally, Nikonov expounds upon the other areas that he is enthusiastic about, specifically regarding machine learning that will transform human decision-making, deep learning, and knowledge management. 

Surprising Tips and Tricks for a Better Night’s Sleep—Ronald M. Bazar, Author of Sleep Secrets: How to Fall Asleep Fast, Beat Fatigue and

Dec 7, 2018 33:35

Description:

It’s easy to tell when we haven’t gotten enough quality sleep—we’re groggy in the morning and sluggish throughout the day—but it’s not nearly as easy to identify why. Is it stress? Lack of exercise? Could it be related to diet? While any one of these factors might be to blame, Ronald M. Bazar suggests a different player in the game—one that may not have occurred to you: your cell phone.


Over the past few decades, electronic devices have become ubiquitous, leading to an unprecedented amount of exposure to electromagnetic radiation. Meanwhile, more and more research is showing evidence of how this is negatively impacting our sleep and health. If you find that hard to believe, consider the fact that most insurance companies refuse to insure manufacturers of cellular devices against liability since there is no way to ensure that the radiation they emit won’t cause health problems down the road. So what's the solution?  


Having worked in the sleep industry for decades and having dealt with his own sleep issues, Ronald M. Bazar has become a sleep expert by researching almost every topic on the issue of sleep, reading articles and books, and trying all the tips and tricks. He’s decided to aggregate all the data and information he’s acquired over the years and put it into a single book called Sleep Secrets: How to Fall Asleep Fast, Beat Fatigue and Insomnia and Get a Great Night's Sleep. Now those who just can’t get a good night’s sleep finally have a chance at finding a solution that works. Tune in for more.  

Capitalizing For Community – Susan Choe, Venture Capital Expert, Founder and Managing Partner at Katalyst Ventures – Venture Capital & Operations Support for Startups and Entrepreneurs—Profitability Meets Patronage

Dec 6, 2018 36:02

Description:

Susan Choe, venture capital expert, founder, and managing partner at Katalyst Ventures (<a href="http://katalyst-ventures.com">katalyst-ventures.com</a>), discusses the importance of funding start-ups that can make an impact on our world in a positive way.


Choe is a seasoned expert with 20+ years of solid experience in applied AI/data-driven business models in interactive content, online finance, and marketing industry segments across Asia and North America. Her approach to venture capital is about supporting and financially funding innovators who are making a difference in the world through technology, in multiple areas. In addition to running Katalyst Ventures, Choe is also the co-founder and managing partner of Visionnaire Ventures, the firm of which she led the first capital raise and subsequent deals with Taizo Son and renowned CFO of Movida, Fuyuki Yamaguchi. Choe has played an instrumental role in the success of a number of companies, founding Outspark, a leading online games publisher, heading up joint ventures with multiple corporations, and maintaining operating roles at many top online tech companies, including Yahoo’s international operations. Choe is keenly interested in helping entrepreneurs grow their businesses through successful investment, service, and business model strategies.


Choe states that Katalyst Ventures is an early-stage AI fund, focusing mostly on firms that are data-driven. She discusses the reasons why Katalyst Ventures explores this particular area of the market, and at what stage they get involved. She explains that many of the companies and entrepreneurs that they invest in have at minimum one commercial partner already on board, and have tested out their products at least at a very preliminary stage. She talks about access to relevant data and the companies and entrepreneurs use of algorithms and natural language processing in their ventures. She cites specific examples of some of the ventures that Katalyst finds most interesting, and she details the intricacies of how they use data and AI. Choe’s firm seeks out solid companies with a fantastic plan for moving their company or idea forward. They work closely with the entrepreneurs to help them solve challenges, and offer strategic advice along the way, as Choe believes that entrepreneurs and business owners can actually change the world.


Choe outlines the various ways that Katalyst Ventures assists entrepreneurs and breakout companies. And as a financial advisory service company, they provide assistance in many areas, from the obvious—venture capital, but also with accounting, operations and systems services, helping visionary entrepreneurs get a solid footing in the market. Katalyst Ventures’ Accounting Services branch offers outstanding operational and financial leadership and company-building expertise, as Choe understands that early-stage companies may not yet have the current volume for a fulltime financial analyst or expert on board. Regarding their Operations branch, Katalyst Ventures can provide top-level assistance to help oversee operations in the early stage, to keep the momentum moving, but in a sound manner. And their Systems Support branch has the operational knowledge and years of expertise to assist entrepreneurs with all of their IT needs. From project evaluation to leading the project, finding appropriate vendors, etc., Choe’s firm can offer valuable assistance that can make the difference in the critical early stage of a company or start-up’s development. 


The venture capitalist gives a historical overview of data and how we have come to use it in concert with modern technology such as AI and machine learning. Medical and operational tasks can be enhanced through the use of predictive technologies. Choe describes how the new technologies can be used to predict possible signs of illness as well as help to inform and educate physicians in the medical field. As she states, regarding data in the medical field, doctors can share data if regulations allow, which creates a larger network that is more aware and efficient. 


Choe talks about her passion for assisting companies that have the greater good in mind. She cites examples of companies and startups that are doing great work, especially in the medical field, helping those in need. She discusses the results that her fund has achieved with various companies they have helped to capitalize. Choe states, of the seven Katalyst Ventures’ company investments, five are in the high growth mode. And as the fund pushes forward with new investments, Choe continues to look for entrepreneurs who bring together the right mix of potential profitability and usefulness to society. 

Sleepy Time–Dr. Chris Winter,MD, Author of The Sleep Solution: Why Your Sleep Is Broken and How To Fix It, Founder of Charlottesville Neurology and Sleep Medicine – Sleeping For Health, How to Get Better Sleep, and the Mystery of Insomnia

Dec 6, 2018 52:55

Description:

Dr. W. Chris Winter, MD, renowned sleep specialist, author of The Sleep Solution: Why Your Sleep Is Broken and How To Fix It, and founder of Charlottesville Neurology and Sleep Medicine (cvilleneuroandsleep.com), delivers a delightfully interesting overview of humans and our sleep patterns, including some practical advice on how to fix our sleep problems. 


Dr. Winter knows sleep, so much so that celebrated journalist and media personality Arianna Huffington dubbed him "The Sleep Whisperer." With over twenty-five years in the field, Dr. Winter has been fully devoted to assisting people, helping them attain better sleep via his clinic, as well as private and/or group consultations. Dr. Winter is an in-demand sleep expert who has been contracted by professional athletes and noted personalities all over to assist with sleep, which is vital for our good health. His book, The Sleep Solution: Why Your Sleep Is Broken and How To Fix It received rave reviews around the globe, considered by many to be an extremely helpful guide to understanding sleep and figuring out how to correct sleep issues. The book received the sought-after accolade badges of ‘#1 New Release’ and ‘#1 Best Seller’ for sleep books on Amazon.


Dr. Winter discusses his early interest in sleep research that developed back during his undergraduate days. From university sleep studies to studies centering on circadian rhythms and light, to how sleep affects astronauts traveling to Mars, etc., there are so many possible areas of study, diverse and interesting, and Dr. Winter states he has a great interest in all of them. 


Dr. Winter acknowledges that insomnia is not really an inability to sleep, but in fact is a state of hyperarousal or hyper fear. Patients with insomnia, as Dr. Winter explains, have a sense of this hyperarousal or fear as they move closer to the time for sleep. They may doubt their ability to sleep or feel aggravated, and worry about the possibility that they will simply just lie there and not experience sleep. However, biologically speaking, insomnia is theoretically impossible, for the body will force sleep onto individuals, at least 5 or 6 hours per 24-hour cycle. Dr. Winter speaks about reframing the problem from a different perspective in order to solve it, and he details the various types of so-called insomnia that people report. Regarding insomnia, Dr. Winter explains that there has been an exponential explosion of writing on the subject of neuroscience and the importance of sleep. He discusses the current high-energy world we live in and how it impacts our sleep, and our ability to get the kind of sleep we need. 


Dr. Winter discusses the media’s understanding of sleep issues and how there is a lot of confusion out there regarding the subject. And he states that many of us don’t truly understand how we sleep or have a sense of the kind of sleep we are getting. The sleep doctor states that consistency is what our brains enjoy most, so the idea that everyone needs to sleep from 11pm to 7am is fallacy. Regardless of our sleep schedule, as long as it is consistent and regular, the brain can process that in a healthy way. It is the constant changing of sleep schedule, such as staying up late some nights, but going to bed early others, and doing that on and on, that can create a problem. 


The sleep expert talks about the importance of understanding how we feel each day, to get a sense of how sleep is impacting our overall feeling. He discusses fatigue and why it is different from sleepiness. Thus the concept of ‘more sleep’ is not the answer; fatigue is the issue often. He cites specific examples from the many people he has helped, and discusses how some are simply given drugs by their physicians to help them sleep, but that the problem is not being addressed at its core. And he debunks many of the trendy sleep theories that do not follow scientific findings. 


Dr. Winter outlines ways that people can take 20 or 30 minute rest opportunities during their days. Putting away the devices, turning out the lights, and finding a horizontal position are the basic steps toward inserting a rest break into our day. And as Dr. Winter states, whether you sleep or just lie there during these breaks, it doesn’t necessarily matter, for it is still a period of relaxation in which you are giving your body an opportunity to sleep if it wants to. 


The sleep doctor relates some of the book reviews he has received, and how even the occasional bad review is something he appreciates, for his expectation is that those reviewers might mention his book to their doctor and that will start a dialogue that just might get them on a track to finding better sleep in their lives.


Dr. Winter is board-certified by the American Board of Sleep Medicine. Additionally, he is board-certified by the American Board of Psychiatry and Neurology (under the American Board of Medical Specialties) specifically as a sleep medicine subspecialist. And he is a prominent member of multiple sleep and sleep research societies, and respected groups. Dr. Winter is an Echols Scholar graduate of the prestigious, University of Virginia and received his medical degree from Emory University. Upon graduation, Dr. Winter completed his neurology residency at the University of Virginia. As Chief Resident, he won a national American Academy of Neurology Teaching Award. Finally, Dr. Winter completed his Sleep Medicine fellowship at the University of North Carolina in Chapel Hill.

Sensing Systems – Rob Frizzell, Co-founder and CEO of OmniPreSense – The Amazing Power of Short-Range Radar Sensors—Increasing Safety, and Efficiency

Dec 5, 2018 23:19

Description:

Rob Frizzell, co-founder, and CEO of OmniPreSense (<a href="http://omnipresense.com">omnipresense.com</a>) delivers a detailed analysis of the sensor and monitoring market, and how new technology and improved short-range radar systems will bring efficiency and increased safety.


Frizzell is a seasoned technical marketing director with a reputation for bringing varied products to market. His wealth of business experience in multiple areas has allowed him to successfully navigate many competitive markets. Frizzell is an expert in project management, product launch, and translating products into customer design-ins, as well as revenue growth pricing strategy. He has worked with many successful companies and their powerhouse products including HP (tablets, notebooks), Asus (tablets, notebooks), Lenovo (tablets, notebooks), Sony (PS3, DTV), Samsung (DTV, smart phone), LG (DTV, smart phones, tablets) and Panasonic (DTV, BD player) as well as many others. Additionally, Frizzell is a technical expert with semiconductors covering touch MCU, RF, high-speed communications, power and flash memory. He has a strong passion for bringing products to market and helping businesses succeed. 


Frizzell presents an overview of the work his company, OmniPreSense, is doing with short wave radar sensors. He states that his team saw a niche in the technical market as little attention was being given to radars, short-range radar as a sensor. Frizzell ‘s Silicon Valley startup develops and sells short-range radar sensors for a myriad of practical applications and implementation with traffic monitoring, drones, robotics, and IoT (smart city, smart home) applications. IoT stands for ‘Internet of Things’ and it is an ecosystem of connected physical objects that are accessible via the internet. OmniPreSense’s innovative solutions allow these systems to view the world in a millimeter wave spectrum. Frizzell states that safety is increased when smarter tech with improved operation lets systems act a bit like a camera, having knowledge about what’s out there, in front of it, etc.


The radar technology expert discusses the many markets, from drones to robotics, to traffic monitoring, etc. that can benefit from their short-range radar solutions. He states that in addition to the monitoring and coordination, the technology can provide real, hard data for users to implement into their future planning. And he gives an overview with specific examples of various radar designs that can be specialized and configured to specific tasks. He discusses the difficulties with drones due to regulations that are still being worked out with governing bodies. But he stresses that drones will certainly be flying overhead in large numbers, in the coming years. 


Frizzell discusses smart cities and how technology can revolutionize traffic movement and efficiency, as well as improve on safety. He provides specific examples related to traffic dangers that could be circumvented with smart cities technology. He details some useful information about the additional ‘awareness’ of smart cities technology, such as the ability to extend crosswalk timers to allow for elderly or others who may need extra time to safely cross an intersection. And on the other side of the coin, the awareness could possibly allow traffic to move quicker off the light by curtailing a crosswalk signal if all pedestrians have safely moved out of the crosswalk.


Frizzell’s team has more than 50 years of experience bringing products to market. The radar sensor expert details some of the exciting new features they plan to build into their technology in the coming years, and the many possibilities for improving the way we live and experience environments. 

Healthy Horizons – Steve Griffiths, PhD, MS, Chief Operating Officer and SVP, Enterprise Analytics at Optum — How Advanced Systems, AI, and Machine Learning Play a Part In the Changing Healthcare Industry

Dec 5, 2018 23:26

Description:

Steve Griffiths, Ph.D., MS, chief operating officer, and SVP, Enterprise Analytics at Optum (<a href="http://optum.com">optum.com</a>), outlines the many changes and improvements that his company, Optum, seeks to bring to the healthcare industry.


Griffiths has a long history of leadership as a health IT executive and his passion is firmly rooted in actionable health care intelligence that brings innovation and change to the increasingly complex health ecosystem. Griffiths uses his experience in the health industry to assist providers as they push to improve practices to value-based care. Griffith believes it is important to treat people, not symptoms, and this care philosophy is the cornerstone of his work. Griffiths has many years experience in the health industry, most recently with Optum, but before his tenure there he was the director of healthcare informatics at Blue Cross Blue Shield of Minnesota. Griffiths holds a BS in Mathematics and Statistics from St. Olaf College, an MS in Biostatistics from the University of Washington, and a Ph.D. in Health Services Research, Policy, and Administration from the University of Minnesota -Twin Cities.


Griffiths provides an overview of Optum, a health services company within United Health Group. He explains the various divisions of Optum and its main branches: Optum Health, Optum Rx, and Optum Insight. As Griffith explains, Optum provides health services across the entire health care system. Their health branch assists individuals and families, helping them attain the high-quality care they deserve, as well as assisting with the management of their prescriptions and health care finances. And Optum works with industry organizations, health plans, and providers as well, tackling the many and diverse challenges in modern healthcare. Their OptumRx branch acts as a pharmacy care services company that seeks to improve and maximize efficiency in pharmacy benefit management. The Optum system allows doctors to make informed decisions, staying current on all the latest developments. And their Data and Analytics branch utilizes the latest groundbreaking technology in artificial intelligence including natural language processing, machine learning, and neural networks to tailor healthcare solutions for specific needs. Optum essentially helps to transform hard data into insights. Griffiths refers to their data analytics as Optum IQ, as that is the center of the intelligence that drives all of their businesses, through the use of data, analytics, and expertise—all supported by technology. 


The technology guru delves into the applied spaces that they see AI advancing, across the spectrum of healthcare industry entities. He discusses the predictive nature of technology that may direct a course of action, such as identifying diabetes patients sooner, predicting possible opioid usage, predicting probabilities for heart failure, and more, essentially assisting doctors, helping to provide a clearer, fuller picture of patients’ health profiles. Additionally, Griffith adds, the data can provide for more efficiency in the overall healthcare process as well, which helps everyone to get the care that they need faster.


Griffiths outlines the specifics of using AI to additionally verify patient information and identity, to ensure safety by helping to avoid human error in records and processing, etc. The AI healthcare technology expert talks about the future advances that are coming in the industry as the tech develops further. From advances within cloud services to clinical programs and clinical prediction of disease, prediction of future costs, and more, the many possibilities for improved care are exciting and Griffith expects Optum to be at the center of innovation within the industry.

ADHD, Autism, and OCD: A Treatment that Works by Tackling the Root Cause--Craig Shimasaki, PhD--Moleculera

Dec 5, 2018 38:44

Description:

More than 60 million Americans have been prescribed some type of psychotropic drug; many of these Americans are children who have shown trouble focusing in school, motor or vocal ticks, obsessive-compulsive behavior, or a range of other signs of varying intensity. Doctors generally aim to treat the symptoms, but what about the underlying cause of the symptoms? And if the cause could be identified, would a psychotropic drug still be the preferred form of treatment?


Craig Shimasaki, Ph.D., joins the podcast to discuss surprising new discoveries on this topic. He’s currently the CEO of Moleculera, a company that opened its doors in 2013 after five antibody targets were discovered in the central nervous systems of children who developed sudden-onset obsessive-compulsive disorder (OCD) after a strep infection. When antibodies attack our joints, we call it rheumatoid arthritis, when they attack our pancreas, we call is diabetes type I, but what do we call it when they attack our brain? According to Dr. Shimasaki and the team at Moleculera, we should call it an infection-triggered autoimmune response known as “molecular mimicry,” which applies not only to OCD but to a subset of ADHD and autism diagnoses as well.


Moleculera has created a blood test that can identify specific markers which, in conjunction with a patient’s clinical signs, indicate whether or not a case of ADHD or autism has an immune-related cause. The patients who fall into this category have improved or seen total resolution of their symptoms after a course of anti-infectives and immune modulatory treatment. Over 1,200 doctors have already ordered the test, 7,600 patients have been tested, and Moleculera continues to accept blood samples from anywhere in the world. 


Dr. Shimasaki offers compelling and informative insight on a range of topics, including how the treatment works and what exactly it consists of, whether or not immune dysregulation could also be involved in schizophrenia, chronic fatigue syndrome, chronic depression, and Alzheimer’s and Parkinson’s disease, and all the details of what Moleculera has in the works, such as the use of machine learning to develop a predictive algorithm for treatment efficacy, and a pharmacoeconomic model that would demonstrate the cost savings of this new method of testing for and treating neurological and psychiatric conditions.


Tune in and visit www.moleculeralabs.com to learn more.

Your Very Own AI-Powered Personal Shopper--Chia-Lin Simmons—LookyLoo, Lucy AI

Dec 4, 2018 39:49

Description:

Online clothing purchases today are premised on the idea that all you need to know is your size or measurements in order to guarantee a good fit, and while men can often get away with this, the reality is that women’s clothing purchases are much more complex. The fact that more than 30-50% of all online apparel purchases are returned is a testament to this, but even those who have the luxury of shopping in person struggle with getting the feedback they can rely upon and feeling confident with their purchases. More than 71% of millennial women send selfies to their friends when trying on clothes, but the chances that they’ll get a response from every friend while they’re still in the store are low.


Now there’s a solution: LookyLoo, an AI-powered social commerce platform that allows users to post photos and receive direct feedback on fashion choices from a cloud of other consumers. Meanwhile, the AI (better known as “Lucy”) learns based on how you and others to vote, leading to stronger, personalized, and specific recommendations. What looks good in fashion is contextual to location and age group, and Lucy takes this into account for every user.


“Fashion is art, and for a lot of people it’s an opportunity to be something beautiful,” says Chia-Lin Simmons, founder of LookyLoo. The app is already enormously popular, and the team at LookyLoo is looking to the future. Where’s that, you might ask? Cosmetics. 


Tune in for all the details and find LookyLoo on Twitter and Instagram.

A Better Sleep, A Better You—Danny Flood—Hack Sleep: How to Fall Asleep Faster, Increase Your Energy, and Wake Up Refreshed

Dec 4, 2018 28:26

Description:

At one point or another we’ve all dealt with it: being unable to fall or stay asleep, or just waking up feeling absolutely exhausted in the morning, wishing we had the energy to do the things we love. For some of us, these problems are chronic and seriously disrupt our quality of life by leading to failing social lives, poor productivity, and even depression.


Danny Flood was one of those individuals until he decided it was time to do something. He experimented with a variety of tricks and techniques to see what worked best, and then compiled them all into a book so that others could benefit from what he’d learned. He joins the podcast to discuss some of the main highlights of Hack Sleep: How to Fall Asleep Faster, Increase Your Energy, and Wake Up Refreshed, which include the importance of keeping the circadian rhythm in sync (and some tips on how to do so), the role of adenosine and adenosine triphosphate in sleep, biphasic and polyphasic sleep schedules, foods that naturally boost melatonin, and recommendations for power napping.


If you or someone you know is suffering from a lack of sleep, Danny Flood is likely to have at least a few tips that'll help. Tune in for more and look for his book on Amazon. 

Reengineering Photosynthesis for Adaptation to Global Climate Change—Donald Richard Ort—University of Illinois at Urbana-Champaign

Dec 4, 2018 41:19

Description:

Global CO2 concentrations have risen from approximately 270 to 400 ppm over the past 150 years with no signs of slowing, and at the current rate, the planet is expected to warm by roughly five degrees Celsius by the end of the century. This will lead to a number of detrimental effects on the environment and human society, not the least of which is a major impact on our current system of agriculture. At the root of this system is the process of photosynthesis, which is the best understood process in all of plant biology, but has always functioned outside of human influence…at least until now.


Donald Richard Ort is a professor at the University of Illinois whose area of expertise lies in the area of photosynthesis and the ability to reengineer it to be adapted for global climate change and to improve its efficiency in agricultural situations. This will be no easy task, considering the fact that CO2 concentration and temperature play competing for roles in a plant’s ability to photosynthesize and survive. 


Professor Ort joins the podcast for an informative and compelling discussion on a variety of topics, ranging from mechanistic computer models used to predict how to optimize photosynthesis under certain conditions, artificial photosynthesis via biomimicry, why breeders have selected for upright leaf angles in grasses over the past several decades, the modulation of chlorophyll concentration in leaves, and SoyFACE, a research facility at University of Illinois where CO2 concentration and temperature are being raised in a controlled environment to learn more about and prepare for what’s coming in the near future.  


Tune in for the full conversation, and stay up to date on the latest research at <a href="http://soyface.illinois.edu">soyface.illinois.edu</a>.

Reshaping Research with the World’s First Community-Owned Human Health Database—Dawn Barry—LunaDNA

Dec 3, 2018 18:21

Description:

As the co-founder and president of LunaDNA, Dawn Barry shares a vision of creating the first ever community-owned human health database comprised of donated DNA, medical, and environmental information, resulting in a scope and scale of data that’s never before been possible. The aim is to provide donors with control, privacy, and transparency over their data, which means that every donor will know where and to what type of research their information is going, and will always maintain the right to delete their data at any time.


Aside from the intrinsic value of empowering research, giving back, and contributing to new discoveries that could enhance all of our lives, donors will acquire shares in the company and receive compensation in the form of dividends with each donation made. The ultimate goal is to reshape research and accelerate breakthroughs in health and quality of life by aggregating and organizing data from a variety of sources, not the least of which are understudied populations.


The team at LunaDNA is patiently awaiting qualification by the SEC; once received, the platform will be open to the public. They’re thinking long-term, with a plan to implement additional portals for sharing electronic health records, and lifestyle and fitness information through APIs such as Fitbit. Interested in learning more? 


Hit play and visit <a href="http://lunadna.com">lunadna.com</a> to sign up to receive the newsletter. 

Virtual Reality Stadiums Featuring Your Favorite Sports Teams, No Matter Where You Are—Symon Perriman—FanWide

Dec 3, 2018 25:11

Description:

There’s nothing quite like the energy and excitement of seeing your favorite sports team in person while surrounded by hundreds or thousands of other fans rooting right along with you, but for the 100 million Americans who don’t live in the same town as their favorite team, this experience is difficult if not impossible to come by. As the president and founder of FanWide, Symon Perriman set out to change this.


FanWide is the world’s largest fan club network that’s connecting likeminded sports fans—regardless of where they live or travel—in a way that until now has only been possible for those who live in the local market. How are they doing it? By creating a virtual stadium at every sports bar around the country where fans can interact, play games, and cheer on their team in unity. But that’s not all: FanWide incentivizes fans for showing up to events by providing rewards such as free beer, contest entries, and the potential to win cryptocurrency tokens that can be spent on game tickets, sports merchandise, and sports apparel.  


“I found that sports were one of the few things that really transcend where you’re from, what language you speak, your gender, your ethnicity…if you can find fans from the same team, it builds up that immediate bond or connection, and we’re providing…an easy way to have that bond and find those people from the same tribe or background through our digital platform, and then bring them together in real-world events,” says Perriman.


Tune in for all the details and visit fanwide.com for an event near you. 

Automatically and Accurately Identifying Sensitive Documents to Ensure Information Security—Ariel Peled—DocAuthority

Dec 3, 2018 16:57

Description:

One of the biggest challenges for any data-centric organization is in understanding the type of data that exists and knowing how best to manage it. When document classification is done incorrectly or not done at all, a variety of possibilities emerge that threaten network security and smooth business operations. Wide permissions on documents open the door to fraudulent activity, and conflicts between the business and IT side of an organization about how to handle certain types of data can cause further problems that increase vulnerability to attacks and data breaches. This is where DocAuthority can help.


By creating an automatic inventory of all organizational data with 99.9 percent accuracy and identifying unprotected sensitive documents, consistent document classification and network security concerns are taken care of in a way that allows business processes to continue uninterrupted. As the CTO and founder of DocAuthority, Ariel Peled joins the podcast to discuss the ins and outs of the products and solutions they offer, as well as new products and initiatives on the horizon. Tune in and visit docauthority.com to learn more. 

Business Boom–Mike Michalowicz,Author,Entrepreneur, Investor, And Business-Success Consultant–Understanding Your Brand, Keeping Promises, and Growing Your Business to New Levels of Success

Dec 3, 2018 32:10

Description:

Mike Michalowicz, author, entrepreneur, investor, and business-success consultant (<a href="http://mikemichalowicz.com">mikemichalowicz.com</a>), delivers an insightful overview of the methods and practices that entrepreneurs can use to grow their businesses and build upon a solid foundation.


Mike Michalowicz doesn’t believe in wasting time; in fact, there is no time to waste when you are a sought-after speaker, consultant, and prolific author of multiple books on business and entrepreneurship. Only in his third decade of life on this earth Michalowicz had already founded and sold two multi-million-dollar companies and was looking for more opportunities to dive into. Riding high on his confidence from recent successes he dove headfirst into angel investing where he proceeded to lose most of the financial security he had put away, but… like a true entrepreneur, he dusted himself off and built it all back again with new ventures and a wise plan to grow strong companies from the ground up, block by block, to success. Michalowicz has received much exposure for his line of successful books and also for his method known as the “Profit First Formula,” which is a means for businesses to ensure profitability from their very next deposit forward and ongoing. 


Mike is the celebrated author of Profit First, The Pumpkin Plan, Clockwork, The Toilet Paper Entrepreneur, and others. He discusses his desire to end entrepreneurial poverty, and his drive to share the secrets that can help businesspeople succeed, and build their dreams. Michalowicz’s first book discussed the concept of hiding profit away, referred to as ‘profit first,’ which caught the attention of business leaders and publishers, and was one of his first methods that business leaders responded to positively. 


Michalowicz details the stages of sales in business and how business owners can take steps that bolster their finances and ultimately their confidence to move their businesses forward, have balance in their lives, and more control of their path. He outlines the variables in business, such as productivity and efficiency, and the importance of choreographing all resources to achieve results and allow a business to run more automatically. 


Michalowicz also stresses the importance of actually taking time to ‘think,’ to process your ideas as they come, and prioritize new avenues for growth. He cites the example of bees and their environment and how each bee understands its role in the ultimate goal of producing eggs, and compares that to efficiency and understanding in business activities that produce higher productivity. Additionally, he discusses the importance of discovering where your survivability and thrivability exist, to understand what your brand promises, and what is the one activity that makes that promise a reality. He discusses the brand, FedEx, and how their success ultimately is based upon their primary function: logistics and delivery of packages on time. Thus it is important to identify what your brand promises and always deliver it. 


The business-success author underscores the importance of having people on your team who can coordinate all the resources and line them up to achieve results via fulfilling customer satisfaction, delivering on promises, innovating, and more.


Michalowicz has moved into his third million-dollar venture and is always looking for new opportunities. He is a former columnist for The Wall Street Journal, former MSNBC business makeover expert and consultant, and is a sought-after keynote speaker on innovative entrepreneurial issues. As a celebrated business author and journalist his methods and practices have become popular tools utilized by entrepreneurs everywhere. His books are go-to manuals for many successful business leaders and his book, The Toilet Paper Entrepreneur, was referred to by BusinessWeek as “the entrepreneur’s cult classic.”

Health & Tech – Jason Andrew, Health Technology Innovator & Chief Executive Officer of Limelight Health – Utilizing Contemporary Technologies to Advance the Health Insurance Industry Via Advanced Quoting and Underwriting Tools

Dec 3, 2018 15:50

Description:

Jason Andrew is the CEO of Limelight Health (limelighthealth.com), and a health and technology innovator and visionary. Andrew discusses Limelight Health’s goal to deliver the most efficient, compelling quoting and underwriting platform for the employee benefits industry.


Andrew’s extensive background as an agent in Silicon Valley where he was engaging daily with game-changing technology motivated and inspired him to launch innovative tools for the health insurance industry. He is an experienced startup entrepreneur with a passion for solving problems in the health insurance, health education, and wellness industries.


Andrew is a recognized health insurance and health reform expert and sought-after leadership advisor in the industry who excels at bringing key individuals together to solve complex problems and innovate. Notably, Andrew served as CEO and founder of Stone Meadow Benefits & Insurance Associates, CEO and co-founder of Coverage Partners, VP business development and co-founder of PK4Tech, and as VP and managing producer of Lawson-Hawks Insurance Associates.


The healthcare and technology expert discusses the current state of operations in his industry. He states that many facilities are utilizing systems and platforms that are 20 or 30 years old and are simply antiquated, unable to keep up with the changing times and technologies. He discusses some of the problems in the industry, and underscores how communication between industry players is critical. And he explains the importance of using API data. API, which stands for application programming interface, allows a service or product to talk to other services or products. Therefore, an API allows data and functionality to be introduced or opened up to other developers and businesses, and it is a common way in which companies exchange their data and services.


Andrew discusses the stage of their production and funding, and his expectations for the future. He states they have customers using their products and more and more companies are coming forward to overhaul their outdated systems, which increases efficiency for companies and consumers alike. He discusses the ratings of various plans from dental to life to health, and how their platform allows for a better grasp of products that are available.


Limelight Health’s mission and primary goal is to deliver ongoing industry innovation and provide time-efficient, current, accurate data to the industry and health community at large. Through their work with comprehensive quoting and decision support, Limelight Health is able to generate successful, fluid end-to-end integrations with the most current technologies. 

Machine Learning, Business Success – Charles Martin, PhD, Data Scientist, Machine Learning AI Consultant, and Chief Scientist at Calculation Consulting – Rapidly Evolving Opportunities For Business Via Machine Learning and Data Science

Nov 30, 2018 42:05

Description:

Charles Martin, PhD, data scientist, machine learning AI consultant, and chief scientist at Calculation Consulting, delivers a thorough overview of the technologies that are helping companies expand their customer base and increase revenue.


Martin is an experienced professional in machine learning, deep learning, data science, and AI software development. He has a long history in the technology field and was instrumental in the development of machine learning systems for major corporations and companies such as GoDaddy, Aardvark (acquired by Google), eBay, and Blackrock. Martin assisted Demand Media in their successful mission to become the first $1B IPO since Google. His specialization in software engineering and ML experience has made him a top consultant for many companies. Additionally, Martin is a full stack developer for web, object oriented, and numerical programming. Martin earned his PhD in Theoretical Chemistry from the University of Chicago.


Martin gives an overview of his company and explains how they specialize in AI and machine learning with a keen focus on translating research into products. Calculation Consulting operates primarily in three areas, strategy, data science, and product development. In regard to strategy, the company seeks to find ways to design new products and predict revenue streams from aggregate data. Regarding data science, their team provides data solutions by applying machine learning algorithms to discover the essential patterns that can drive traffic, engagement, and sales. And in product development, Calculation Consulting builds and deploys contemporary, end-to-end, highly sophisticated, cloud-based software systems.


The technology visionary discusses some of the areas his company excels in, such as semantic search and matching. Semantic relates to ‘meaning’ in language. Semantic search improves search accuracy by more fully understanding a searcher’s intent via the contextual meaning. By utilizing concept matching, synonyms, and natural language algorithms, a semantic search can produce a better interactive search and deliver more specific personalized results. He discusses some of the prototypes he has built in this area of the tech field. Martin expounds upon the ways that research has progressed especially thanks to Kaggle, the successful online community of data scientists and machine learners that is powered and owned by Google, Inc. Kaggle enables its many users to locate and publish data sets, to intensely explore and build models in a web-oriented data-science environment, work in connection with other data scientists, enter their work in competitions, and so forth. Martin explains how Facebook, Google, and Amazon alone have put thousands of their top engineers to work on these types of open source projects to develop the most innovative research and turn it into real tools and products.


He discusses some of the top open source tools for natural language processing, and his techniques for running them in actual production, working with queries, etc. in the real world. He explains that the process of pulling all this information together, understanding how to utilize the techniques, methods, etc. is an area of their particular expertise.


Martin explains in detail the methods of analyzation and how the technology is useful in a practical business work environment. He discusses their project phases and how they assist companies, citing specific examples of companies they have helped, to use neural networks to solve business-specific problems. Martin discusses click-thru and view prediction models, and gives examples of businesses that Calculation Consulting has assisted in their quest to learn more about customer behavior to increase revenue. Specifically, Martin details ways to increase click-thru efficiency using machine learning, and other tips to drive interest and sales.


The machine learning specialist relates how, today, there are so many problems that can be solved via machine learning technology. He discusses online traffic and clicks and the successes he has had growing companies with the technologies, some of which have seen their revenue streams expand to amazing new levels. Further, Martin discusses the reservations that some high-level managers and even CEOs may have about making the transition to the new technologies, in spite of the exponential advantages for their companies. But Martin states that while some companies are slow to move, those with the right mindset, who hunger to jump into the AI arena, are clients that he and his team at Calculation Consulting can help to reach new levels of success in business. 

Cancer Research – Jane Antony, Postdoctoral Researcher, Stanford Medicine, Stem Cell Biology and Regenerative Medicine – DNA, Therapies, Cell Biology, and The Quest For New Treatments

Nov 29, 2018 42:27

Description:

Jane Antony, postdoctoral researcher, Stanford Medicine, Stem Cell Biology and Regenerative Medicine, delivers an important and thorough overview of the current state of cancer research and methods that may lead to promising new discoveries.


Antony worked toward her Ph.D. through a unique joint program of the National University of Singapore and Imperial College London to bolster her study and understanding of cancer cell biology. She has been an active member of various research groups in Singapore and the UK that focus their efforts primarily on cancer biology, ovarian cancer, metastasis, signal transduction, and therapeutics. Her current work pertains to the identification of innovative therapeutic targets in invasive breast cancer illuminating differential signaling schemas in tumor heterogeneity. Antony is constantly curious, with a passion for understanding the link between metastasis and cancer stem cells.


Antony discusses her current cancer research. She states since cancer is an intrinsic disease, whatever you use to target it will impact the normal healthy tissue as well. Generally, a disease's etiology, or cause, can be classified as intrinsic, extrinsic, or idiopathic. Antony’s particular interest is in regard to metastasis and how cancer spreads. Antony states that many cancers can be removed surgically and can utilize therapies that shrink the cancer cells, but if it spreads to other organs it becomes more difficult to treat. Antony gives a detailed analysis of what is currently known about DNA as it relates to cancer growth. She describes the different types of cancers, how they metastasize, and typically where they travel to, or could. Additionally, she provides an in-depth overview of the current therapies such as radiation and chemotherapy. In regard to radiation therapy, it certainly has an effect on normal cells as well, and chemotherapy, unfortunately, becomes less effective over time and multiple treatments. 


Antony talks about some of her work and areas of particular interest such as tumor suppressors. Understanding how tumor suppressors are involved in the development of cancer, specifically genes that regulate Receptor Tyrosine Kinases (RTKs) can quite possibly provide some important answers. A gene of great interest is the OPCML, which is present in healthy, normal cells but is switched off in cancer, which makes treatment very difficult with lowered chances for recovery. Understanding how this gene functions in cells is a critically important issue. Targeting genes that regulate RTKs can lead to possible gene-based cancer therapies for patients.


Antony details other important developments in research, such as limiting dilution assays (LDA). LDA is designed to define an undetermined frequency of effector cells within a population. They are dose-response assays that enable detection of a positive or negative immunoresponse in each unique culture within replicates that vary in the number of actual responder cells tested. By calculating stem cell frequencies researchers can study how stem cells are evolving throughout treatment.


Antony describes her findings in regard to stem cells and various types of cancers. She states that in blood cancers, the methods are somewhat different, in that bone marrow is removed and then reinstated after treatment has flushed out the affected area. Obviously, this is a treatment advantage of liquid cancers, for solid tumor cancers cannot benefit in the same way due to their form. And she talks about an assortment of other interesting trials that are underway that may provide further answers of great benefit to science and medicine.


Antony is a postdoctoral member of the American Society for Cell Biology (ASCB), as well as a member of the EMT International Association, and an associate member of the American Association for Cancer Research. She holds a Doctor of Philosophy from the National University of Singapore, a Bachelor of Engineering from the National University of Singapore, and a Doctor of Philosophy from Imperial College of Science, Technology & Medicine.

I See Molecules – Dr. Sabrina Leslie, Associate Professor of Physics and Quantitative Life Sciences at McGill University – Molecule Imaging and Investigation, Studying Interactions For Scientific and Medical Advancement

Nov 29, 2018 26:04

Description:

Dr. Sabrina Leslie, Associate Professor of Physics and Quantitative Life Sciences at McGill University, leads listeners on an interesting journey into the complex and important world of molecule imaging and research.


As an experienced researcher and respected university leader at McGill, Dr. Leslie founded her single-molecule imaging laboratory in 2012. The lab was instrumental in the development of novel techniques to discover and explore complex interactions and dynamics of macromolecules. Dr. Leslie has pursued doctoral studies in optical physics, has completed extensive research on biomolecules in liquids, and explored her passion for imaging in a health sciences context. She is a recipient of a Mary Fieser Postdoctoral Fellowship, and her work at Harvard led to the invention of a single-molecule imaging technology known as Convex Lens-induced Confinement (CLiC). And it was this groundbreaking work in the field that thrust her onto the international stage as a noted pioneer in single-molecule investigations with a broad range of applications. Dr. Leslie earned her Ph.D. in Optical and Atomic Physics at the University of California at Berkeley


Dr. Leslie discusses her lab’s intensive work deconstructing molecular interactions to answer questions in biology and develop new drugs for medical and therapeutic applications. She talks about the importance of time scales, speed of camera, and resolution, in their work as they seek to visualize the interactions in real time. By using cameras they are able to watch molecules for a long time and deconstruct the methods of operation.


Collaborating with biochemists and cancer scientists, as well as applied mathematicians, the Leslie Lab’s single-molecule investigations of protein and DNA interactions, have provided significant new information about gene regulation mechanisms. Specifically, Dr. Leslie’s work has also been focused on exploring a wide range of interactions and dynamics of proteins and DNA, as well as other macromolecules, and with regard to molecular shape and environment. 


The macromolecule researcher details her lab’s groundbreaking work with the imaging technology known as Convex Lens-induced Confinement (CLiC). As she explains, the process works by essentially squeezing the tiny molecules into little traps so that the essence of the molecule is completely held in focus, viewable from all angles. And by utilizing fluorescent labels they are able to closely track them for observation. 


She details some of their current research regarding DNA binding with a focus on applications and therapeutics, etc. As they continued their experimentation they began introducing other molecules and polymers, to fill up space and then observe how DNA probes find their target sites. As she states, they have a particular interest in the nexus between the physics and the biology, where structural elements can have an impact on the biochemical reactions. Further, she talks about some surprising discoveries regarding proteins and droplet formation simulation. 

In concert with biochemists in Montreal, Dr. Leslie’s team is instigating CLiC studies of non-membranous organelles (NMOs). Liquid droplets form when proteins and nucleic acids phase-separate from cellular material, similar to how oil separates from water. Importantly, there is significant evidence suggesting that misregulation of MMOs is associated with select diseases such as Alzheimer’s.


Lastly, Dr. Leslie expounds upon some of the areas of research they are most excited to dig into, such as gene editing, and she gives an overview of their collaborations with pharmaceutical companies on oligonucleotide therapeutics. (Oligonucleotide therapeutics is an inventive class of biopharmaceutical products composed of short strings of synthetic nucleotides that resemble the actual building blocks for DNA.)

The Future of Financials – Rayne Steinberg, Chief Executive Officer of Arca Funds – The Fast Moving Digital Financial Marketplace and How Investors Can Dive In And Make Sense of It All

Nov 29, 2018 21:55

Description:

Rayne Steinberg, chief executive officer of Arca Funds (<a href="http://arcafunds.com">arcafunds.com</a>), discusses the complex and constantly evolving digital marketplace, financial products, and ways that qualified investors can successfully navigate the vast sea of new currencies and platforms.


Steinberg is a seasoned securities structuring and risk management professional. He has played an instrumental role in many businesses, including his influential contributions as co-founder of WisdomTree. Steinberg was responsible for raising capital, building and overseeing the sales team that successfully raised $50 Billion in ETF AUM. Steinberg earned a Bachelor of Science degree from the University of Pennsylvania’s prestigious Wharton School of Business.


Steinberg discusses his early journey into the business, including his time as co-founder of WisdomTree. He explains the financial products and fee structures, and how high fee was a problem that made it difficult for industries to disrupt themselves. His interest in crypto was that it was an asset class for people to invest in, but it was also a novel wrapper in which to wrap many and various financial service products. Specifically speaking, ETFs are wrappers that are comprised of multiple securities representing an overall investment strategy.


Steinberg explains his company’s model and intentions. Arca Funds applies to sound, institutional-grade asset management processes to the future-forward crypto and blockchain-investing arena. Arca Funds’ primary focus is on stable regulation and security, compliance, as well as custody and risk management. Steinberg discusses how our current system has largely been centralized, with individuals giving their trust to authorities to maintain their transactions, etc. Thus, the new model of crypto represents a reconfiguration of that system, as its approach is one of decentralization. He gives an example of how in the new digital ecosystem, individuals are the custodians of their own passcodes, and so forth, placing a higher level of responsibility upon the individual. As Steinberg states, with the new freedom in the digital market comes new risks as well, and Arca Funds was designed specifically to help individuals bridge the gap between the old and new, to find their footing in these rapidly expanding digital markets. The Arca Funds platform allows for safe experimentation as users gain experience in the markets. 


Steinberg outlines many of their products. Arca launched a series of quality funds designed to offer greater diversified and compliant exposure to the expanding crypto asset class. And down the road, they plan to develop unique tokenized products that will significantly disrupt and replace the aging landscape of centralized, expensive financial service products that are not easily converted into cash. And as there is the risk in the markets, Steinberg states that their platform is only available for high net worth individuals and qualified buyers, as is defined by regulators. He explains the intricate details of their various products’ structures, and who they would be attractive for, and why. And he details how Arca Funds is able to assist in the qualifying of asset products that come into the marketplace. From Bitcoin to Ethereum, regarding hedge funds, and so much more, Steinberg’s Arca Funds evaluates the many opportunities and provides real, sound information on them. And as the products are not just security products but are also technology products, Arca Funds’ team utilizes a thorough process to get to know the products, and the technology, as the digital market is quite complex for the average user. As such, Arca Funds’ returns typically better the averages. 


The Arca team systematically and thoroughly combines their many decades of institutional asset management experience; a broad history of successful, relevant business creation; and the technical expertise to create real value for the individuals they service.


Satisfying Slumber – Michael Grandner, PhD, Arizona College of Medicine – Why We Need Sleep, How It Affects Functioning, And What To Do When We Aren’t Getting Enough Quality Sleep

Nov 28, 2018 44:08

Description:

Michael A. Grandner, PhD, Arizona College of Medicine, provides an overview of the many aspects of sleep, how it impacts functioning, and the ways we can improve the quality of our sleep.


Dr. Grandner is an experienced researcher, noted speaker, and respected colleague at many prestigious institutions. He serves as the director of the Sleep and Health Research Program at the University of Arizona, and as director of the Behavioral Sleep Medicine Clinic at the Banner-University Medical Center. Additionally, Dr. Grandner is an assistant professor in the departments of psychiatry and medicine in the UA College of Medicine, assistant professor of psychology in the UA College of Science, as well as an assistant professor of nutritional sciences in the College of Agriculture and Life Sciences. He is certified in behavioral sleep medicine by the American Board of Sleep Medicine.


Dr. Grandner discusses the connections between sleep and health and how it plays an important role in many and various areas of functioning. He states that a lot of their research focuses on finding ways to help with sleep improvement. He looks at quality and quantity of sleep, timing, when people are sleeping, and why. He gives details on the range of ways they study sleep in their laboratory. He talks about the various types of emerging technologies that can assist them with measuring the aspects of sleep. As sleep exists deep in the brain, it is impossible to perfectly measure sleep, thus Dr. Grandner states that they must measure around it, guessing at other measures such as movement and brain wave activity, etc.


Achieving healthy sleep is crucial for great overall health, cardiovascular health, and is also an important factor in obesity, diabetes, and psychological well being. And as such, when we don’t get enough of it, or the quality level is low, functioning can be impacted in many ways. Interestingly, Dr. Grandner points out that many people actually degrade their own opportunity to achieve quality sleep by reinforcing periods of insomnia. As he states, the best thing to do when you’re in bed and can’t sleep is to get up. Lying in bed and trying to fight it only reinforces the state, essentially teaching your brain that bedtime is a time for brain activity and thought. Thus getting out of bed and taking on some sort of activity till you feel ready to sleep could prove helpful.


Dr. Grandner outlines some of the research and interesting studies his team is involved with currently as well as other studies on the horizon. Current research focuses on the ways sleep and sleep-related behaviors could be connected to cardiovascular disease, obesity, diabetes, neurocognitive functioning, mental health, and even longevity. Their projects have been funded by the National Collegiate Athletics Association (NCAA), the National Institute on Minority Health and Health Disparities (NIMHD), the National Heart, Lung, and Blood Institute (NHLBI), the National Institute for Environmental Health Sciences (NIEHS), and the American Heart Association (AHA).


Their community-based studies consider a vast swath of issues from social environment, access to care, stress, diet, and exercise, as well as aspects of cardiometabolic functioning, to look at the ways sleep is related to each. Dr. Grandner seeks to develop new tools to help people gauge the kind of sleep they are getting and how to improve it. In regard to sleep, Dr. Grandner states, it is not something that you can command. We need to give ourselves the right environment, mentally and physically, that will allow sleep to happen. He discusses the quality versus the quantity, and the ways to evaluate that, as well as the importance of regular sleep patterns.


Dr. Grandner discusses the internal body clocks that govern function, and the various types of personalities and genes that play a role in sleep schedules. He discusses the sleep-wake system versus the circadian system, which relates to the biological process that displays an endogenous, entrainable oscillation of approximately 24 hours. He explains how hormone shifts and rhythms can be changed, shifted, and blunted, and how light can help with making adjustments, in regard to the winter blues, seasonal affective disorder, etc.


Dr. Grandner has published over 100 articles and chapters on myriad issues relating to sleep and health. His significant work in the field has been cited over 2,500 times. Dr. Grandner is associate editor of the recognized journal, Sleep Health, and he serves on the editorial boards of various other journals: SLEEP, Journal of Clinical Sleep Medicine, Sleep Medicine, and others. He is a sought-after speaker on the connection between sleep and good health and as such has been invited often to the National Institutes of Health, and has presented for the US Congress.

Insight from One of the World’s Leading Experts in Paleo Nutrition--Robb Wolf--New York Times Best-Selling Author of Wired to Eat and The Paleo Solution

Nov 28, 2018 1:04:52

Description:

It’s true: we’re wired to eat, but what should we be eating? Is there a one-for-all holy grail of diets that we just haven’t found yet, or is an “appropriate” diet something that varies from person to person? How much should we be exercising, and does stress really contribute to weight gain? The answers you get will probably depend on who you’re asking. Today’s podcast focuses on Robb Wolf’s opinion on these and a variety of other topics.


As one of the world’s leading experts in paleo nutrition, author of two books on The New York Times Best Seller list (The Paleo Solution: The Original Human Diet and Wired to Eat), and former research biochemist, it’s safe to say his opinions carry a lot of weight. Tune in for an intriguing and eye-opening conversation that touches on the role of diet, lifestyle, genetics, epigenetics, socialization, and the gut microbiome in overall health and quality of life.  


Visit<a href="http://robbwolf.com"> robbwolf.com </a>to join his newsletter and access a plethojump-start materials that’ll help jump start your journey to health. 


Here is the article: https://jamanetwork.com/journals/jama/article-abstract/2679460

Renewable Energy Generation Using Aluminum--Josiah Nelson, CEO and Tirthak Saha, Co-Founder and CTO--Trolysis

Nov 28, 2018 23:05

Description:

Talk of the need for a renewable, clean energy source is everywhere these days, but until now, aluminum hasn’t really been a player in the discussion. Why not? Josiah Nelson asked the same question when a mistake in the lab led him to observe an unexpected reaction between water and aluminum that’d been stripped of its outermost layer. The result? An intense bubbling created by the oxidation of water, leaving nothing behind but hydrogen and aluminum oxide.


He soon realized he’d stumbled upon something that could change the world: a 100% renewable way to make hydrogen and electricity with efficiencies comparable to fossil fuels at about one-fifth of the cost of non-renewable and unclean hydrogen-generating processes. That’s not all: this process of hydrogen generation is scalable and reliable enough for industrial manufacturing.


It didn’t take long for him to join forces with Tirthak Saha in the founding of Trolysis, a company devoted to bringing this technology to market and ultimately powering the world. With the demand for hydrogen hovering somewhere around 90 billion metric tons per year in the US alone, Nelson’s claim to have found the holy grail for renewable energy enthusiasts might just be legitimate. Both Nelson and Saha offer an exciting and engaging discussion about the Trolysis technology, the underlying chemistry at play, and the three main problems with other methods of hydrogen regeneration. Hit play and learn more at trolysis.com. 

Algorithmically Mapping the Future of Your Education and Career--Hamoon Ekhtiari, CEO--FutureFit AI

Nov 28, 2018 35:10

Description:

The traditional pathway to what’s considered a “successful” career is becoming less and less popular, and for some who find themselves under circumstantial constraints, it’s nearly impossible. But at the intersection of the rapidly changing worlds of employment, education, and technology, seeking alternative routes to a successful life has never made more sense, and perhaps never been so potentially lucrative. But how do we know where to begin, and how do we know what type of support will be necessary along the way?


According to Hamoon Ekhtiari, the answers might be simpler than we think: “We need to have a Google Maps for the future of working and learning; just like Google Maps helps us navigate the physical world, we need something to help us navigate the unpredictable world of work and learning,” he says, and as the CEO of FutureFit AI, this is exactly what he’s creating. Imagine being able to locate yourself in terms of the skills and experience you currently bring to the table, set a career, income, or educational destination, and then sit back while AI algorithms use millions of data points to deliver a variety of potential pathways based on your specific requirements; it’s quite literally like a roadmap to your future life. That’s not all: you’ll also receive mentorship, support, and coaching for arising needs or unexpected roadblocks along your route.


FutureFit AI is currently working with numerous employers, enterprises, and government institutions that want to help their employees upscale and rescale their jobs alongside the changing landscape of work and technology, expanding the realm of possibilities to include more than just promotion-based career advances. Interested in learning more? Tune in and visit <a href="http://futurefit.ai">futurefit.ai</a>. 

War on Waste – John Kupice, Chief Executive Officer of H-Source – How A Virtual Marketplace Is Offering Hospitals and Healthcare Clinics New Opportunities to Decrease Financial Waste and Continue Providing Healthcare To Their Communities

Nov 27, 2018 21:18

Description:

John Kupice, chief executive officer of H-Source (<a href="http://h-source.com">h-source.com</a>), provides an interesting overview of the important work his company is doing to help hospitals and clinics save money so they can do what they do best—provide quality healthcare to their communities. 


As Kupice explains, H-Source is a hospital to hospital/ medical facility to medical facility marketplace. As he states, shockingly, the medical marketplace in the United States has a ten billion dollar waste problem, regarding medical supplies and products with an expiration date, and an additional five billion in non-controlled pharmaceuticals. Kupice’s company, H-Source, has created a cloud-based marketplace in which hospitals and medical facilities can exchange equipment and products, etc., instead of throwing them out or having them end up in landfills. As Kupice describes, H-Source is sort of an Amazon meets Linked In approach to a forward-thinking marketplace that is changing the industry.


Kupice is the CEO of H-Source and serves on its board of directors as well. Prior to becoming the company’s chief executive, Kupice assisted its founder with the capital raise and development of their business model. Kupice has a storied career in business, notably leading many formidable companies in multiple industries. He was VP of Development for TruCare Solutions, Inc. where he played a vital role in the consolidation and analysis of crucial patient outcome data for alternative treatment modalities. Outside of the healthcare industry, Kupice was chief executive officer for a successful entertainment technology company and was instrumental in attaining company goals regarding reseller and supplier relationships, capital acquisition, and merger and acquisition of competitors. Additionally, Kupice put ten years in at Ernst & Young, LLP, most recently as national director of the Lawson Practice where he provided program management and implementation assistance for clients in a myriad of industries, including healthcare. Kupice holds a B.A. in accounting from the University of West Florida.


Kupice discusses the many and various types of products that are regularly thrown out from catheterization laboratories and operating rooms, etc. due to physician preference, supplier demands, and other issues. Through H-Source, hospitals and medical facilities can now recover up to forty cents on the dollar or more for their items, whereas previously they were total write-offs, tossed out at a total loss, donated, or sold off at lower rates, perhaps ten to twenty cents on the dollar or lower. Kupice outlines how hospital margins are narrowing, with rising costs, especially in labor costs, and thus mid-sized to large hospitals are having significant problems staying in business, keeping their doors open. Thin margins are making hospital administrators critically rethink every expenditure, and all waste and H-Source is seeing an influx of new customers regularly.


As many hospitals have been forced to downsize their labor staff, Kupice states that some are actually bringing new staff on board, specifically to utilize H-Source and its tools to find ways to cut other costs and create value. Kupice muses about how the changes are bringing key players together to create a unified healthcare industry that works more efficiently and provides savings for everyone. But beyond the dollars and cents, and the economic metrics, there is another wonderful aspect of H-Source’s marketplace, and it pertains to jobs and patient care. As many large hospitals can benefit by selling off items and cutting their financial waste, small community healthcare facilities often become the buyers of these items. Allowing small community facilities an opportunity to buy as they need, and avoid costly large orders, it often makes the difference between keeping a part-time nurse on staff and letting him or her go. Thus, the economics and savings create better financials for small facilities that enable them to keep their staff gainfully employed, which means more quality care for small communities in need. 


H-Source’s innovative marketplace model is improving the healthcare industry across the board, from the largest city hospitals to the small town community clinics. And Kupice is excited about the future possibilities that will help bring quality healthcare to more people by cutting waste and increasing opportunity. 

Click Here to Save a Child’s Life – Troy Hickerson, Global Nutrition Activist and Co-Founder of Active For Good – How Getting Active Can Improve Your Own Health AND Save the Lives of Malnourished Children Around the World

Nov 27, 2018 14:42

Description:

Troy Hickerson, global nutrition activist and co-founder of Active For Good (activeforgood.com), delivers an important, informative overview of the crucial work that needs to be done, and what we can all do, to save malnourished children globally. 


Troy Hickerson is a passionate business leader. For nearly twenty years Hickerson has applied his in-depth knowledge of problem-solving and opportunity creation to help small to mid-sized companies utilize technology to succeed. As a cloud services expert, Hickerson wanted to find a way to merge his technology experience with his personal goals of serving those who suffer from extreme poverty and malnutrition. As Hickerson states, one-quarter of children in the developing world are malnourished.


Hickerson splits his time between assisting startups and established businesses with service business operations, positioning and strategy, business model analysis, and problem-solving, and pushing his organization, Active For Good, forward on its mission to assist in the global nutrition problem. Hickerson explains the connection his organization makes between the world’s populations, between those who want to lose calories and those who need calories. Through a series of programs Active For Good runs, for every calorie someone burns when they are working to stay active can equate to a calorie of food given to a malnourished child. By creating activities and teams, users of the platform are motivated to help themselves while simultaneously helping others in the world. 


Making a difference is what Active For Good is all about. Hickerson talks about the important issues that Active For Good tackles in its mission to create change and help people globally. Active For Good was initiated by the founders of MANA Nutrition, a non-profit organization that manufactures RUTF (Ready to Use Therapeutic Food) used to combat severe acute malnutrition and childhood death. Hickerson explains how MANA ships over 500,000 packets of RUTF per day as they provide life-saving therapeutic food via partners such as Save the Children, World Vision, Doctors without Borders, UNICEF, and USAID.


Through the Active For the Good app, wellness teams, individuals, and employee groups can take the challenge, sign up online, and get started with healthy activities that will not only improve their health but will generate much-needed revenue so life-saving nutritional foods can be delivered to those in need. Activity is tracked through Google Fit, Apple’s HealthKit, or similar tracking tools, and company employees, friends, or whomever, can engage in competition that keeps it fun while working toward personal goals, and goals for humanity. Through the point system, points count toward meals for children. And the app shows you what the process is like and creates an educational opportunity to learn about the areas of the world where people are truly in need. 


Hickerson discusses the enthusiasm he sees in people when they get a sense of how their small actions can make an enormous impact on children’s lives globally. As he states, nutrition is critical in a child’s developing years, and there can be severe consequences if a child is malnourished, even if they survive. Thus the Active For Good mission provides an opportunity for companies, groups, and individuals to lend a hand to those who need it, which is a vital part of the human experience.


You Are What You Eat–Dr. Andreas Eenfeldt, MD, Founder and CEO of Diet Doctor – Good Nutrition, Lifestyle Choices, and A Plan For Sustained Good Health

Nov 27, 2018 35:50

Description:

Dr. Andreas Eenfeldt, MD, founder, and CEO of Diet Doctor (dietdoctor.com), delivers an informative presentation on the nutrition to health connection.


Dr. Eenfeldt is a Swedish medical doctor who specializes in family medicine. As founder and CEO of Diet Doctor, Eenfeldt leads a team of forty coworkers. For more than ten years, Dr. Eenfeldt has maintained the biggest health blog in Sweden with a tremendous following, and he is the author of a best-selling book on nutrition that is now available in eight languages. Throughout his extensive career as a family physician, he has treated many patients with low-carb, high-fat diets and has helped many people with obesity and type 2 diabetes. With a sense of urgency to get his message to a larger audience, Dr. Eenfeldt sought new opportunities to spread the word thus Diet Doctor was born. Diet Doctor is growing daily and is the largest low-carb and keto website in the world, now with more than 350,000 visits daily.


Dr. Eenfeldt discusses how nutrition is not really a major focus of study in medical school curriculums, and as such medical students interested in the nutrition to health connection must largely study it on their own. He talks about the effect of nutrition and diet on individuals as they age. With conditions such as diabetes and blood pressure, diet becomes even more important he states. 


As their mission states, taking back your good health in an often-unhealthy world requires some critical thinking, and acting differently. We must put our trust in science and nature and avoid the fads and quick fixes. Changing lifestyle choices and increasing good nutrition can truly make an impact almost as quickly as you begin, but it takes dedication. Diet Doctor seeks out the most credible, trustworthy science and practical knowledge about health, and provides it to readers and subscribers in an easy, interesting manner. Their goal is to make low carb an option for anyone who wants to give it a chance and see a difference, to empower people to tune into their health and make positive changes. For as they state, regardless of any attempt to do so, you cannot outrun a bad diet.


The Diet Doctor CEO talks about successes he is proud of, as many patients are able to decrease or discontinue certain medications when their test results show that his methods have brought their lab levels back into normal ranges. Dr. Eenfeldt talks about the many ways that his website provides valuable information and options for individuals, and he discusses some of his hopes for the future in healthcare and nutrition, including a possible clinic that can offer direct community outreach.


Dr. Eenfeldt discusses some of the current trends in the diet and nutrition area. He talks about the fallacy of fats, and how avoidance of natural fats is not a good thing. He discusses the trend of moving back to natural fats such as real butter and eggs, and the trend of moving away from the concept of calorie counting. He states that calorie counting doesn’t work. But with a low carb diet, when you remove the sugar and remove the starch, people tend to eat less spontaneously, and the benefits naturally occur. And with a low carb diet that drives insulin levels lower, the body burns excess fat more easily. 


The Diet Doctor discusses hormonal changes and how it affects a low carb diet. He cautions against empty calorie drinks and foods that offer no nutritional value. Additionally, Dr. Eenfeldt provides his analysis on aging and hormonal issues that can certainly make the challenge of maintaining the weight of our youth a bit more difficult. But Dr. Eenfeldt is a firm believer of the view that as long as our health is good and we feel great, it may be best to accept that our bodies have changed outwardly somewhat. Our health is the most important thing of all, and nutrition is the key to reaching optimum health. Ultimately, diet and lifestyle are the essential key elements to achieving good health, and Dr. Eenfedt is dedicated to the mission of bringing quality health education and methods to everyone. 

The Brain to Gut Microbiota Connection – Emeran A. Mayer, MD, PhD, David Geffen School of Medicine at UCLA – Diet, Stress, and the Mind – Making Sense of the Brain-Gut Connection

Nov 26, 2018 45:34

Description:

Emeran A. Mayer, MD, Ph.D., David Geffen School of Medicine at UCLA, delivers an informative overview of the brain to gut connection. Dr. Mayer serves as director,G. Oppenheimer Center for Neurobiology of Stress and Resilience (CNSR); co-director, CURE: Digestive Diseases Research Center; and is an experienced professor of medicine, physiology, and psychiatry.


Dr. Mayer attended the Ludwig Maximilian’s University in Munich, Germany where he received his MD/ Ph.D. Dr. Mayer completed his residency at the Vancouver General Hospital in Vancouver, Canada and his GI fellowship training at the UCLA/VA Wadsworth Training Program. With a lifelong fascination for research, Dr. Mayer has applied his extensive knowledge toward a career studying the clinical and research aspects of brain-body interactions, with a particularly intensive focus on bidirectional communication between the brain and the gut in regard to health and disease. 


Dr. Mayer discusses his long career and findings that led to the decision to write his new book, The Mind-Gut Connection. He details particular studies that influenced the material that is discussed in-depth in his books, such as one study that involved testing of individuals who were given a probiotic cocktail and then observed regarding their symptoms and brain function. His surprising findings in this study pushed him to include the gut microbiome in all of his studies thereafter.


Dr. Mayer is considered to be one of the world’s top expert investigators of the many brain-gut microbiome interactions in GI disorders, with specific regard to functional and inflammatory bowel disorders as well as obesity. Dr. Mayer’s exceptional work has been noted worldwide and as such he has enjoyed continual funding for his important research from the National Institutes of Health (NIH) since 1989.


The digestive research expert reveals his findings on multitudinous studies of microbial function. He details the use of interventions such as cognitive behavioral therapy (CBT) in his studies, specifically regarding gastrointestinal maladies such as irritable bowel syndrome (IBS) and others. His findings indicated that the CBT was instrumental in improving symptoms for IBS significantly. Dr. Mayer’s work concluded that the brain has incredible influence on microbial composition. Dr. Mayer relates how the autonomic nervous system affects the environment of the gut, thus stressors in our lives have a direct impact on our digestive system’s functioning, from secretions to peptides, to blood flow, and beyond. 


Dr. Mayer speaks about causality and the models that they have studied to explain microbiome disorders. He discusses the circular process in which the brain sends signals to the gut, the back and forth signaling that impacts functioning. Further, he discusses in detail gene expression profiles, proteins, metabolites, etc., and the connections between various elements of his research, as well as the collective research, being done globally in regard to these brain/gut issues. 


The neurobiology researcher provides some background on other studies that focus on teaching the brain to send different signals, as well as diet in regard to gut microbial function. Dr. Mayer states that plant-based diets are by far the best diets for functioning, and the microbiome in general, according to epidemiological studies. He discusses how metabolites are affected by diet, and how gut function will revert when special diets are changed or discontinued. He provides detailed information on specific diets and his thoughts regarding them. As Dr. Mayer states, exposure to antibiotics and dietary patterns of pregnant mothers, etc. all impact microbiomes. He explains the differences that exist in the microbiomes of various and diverse populations of people, and how diet can impact our gut functioning rather quickly once changes are made, for example switching from fast food to a Mediterranean diet, etc. 


Dr. Mayer is the director of the Gail and Gerald Oppenheimer Family Center for Neurobiology of Stress, and is currently PI of a NIH Center grant on the sex differences in functional GI disorders, on a consortium grant of brain-bladder interactions, and a RO1 grant on brain imaging in IBS. As a leading expert in microbiome studies, Dr. Mayer seeks to continually dig deeper into the connections between the brain and the gut in his quest to find new ways to improve health for everyone. 

Locally-Sourced and Nutrition-Packed Juices, Cleanses, and Kits—Andrew Walker—Little West

Nov 26, 2018 26:27

Description:

“A little west goes a long way,” says Andrew Walker, echoing the slogan of the company he and his wife founded about six years ago. With just one brick and mortar shop in Los Angeles, California, Little West is a favorite among those seeking a variety of superfoods alongside the company’s main focus: locally-sourced and nutrition-packed juices. The menu includes 14 different no-sugar-added, cold-pressed juices packed with minerals, vitamins, and anti-inflammatory roots with varying levels of sweetness to meet anyone’s preference. They also offer a variety of cleanses and kits, some for beginners and some for those seeking more advanced, “master” cleanses.


Walker discusses the details of the Little West juice-making process, the differences between each cleanse offered and why one may be better suited for some individuals than others, the importance of preparing for and coming off of cleanses, the benefits of small-batch cold pressing versus the methods used by most other juice bars, and the connection between food sensitivities and gut health.


Interested in trying it for yourself? Tune in and visit <a href="http://littlewest.com">littlewest.com</a> to order from anywhere in the nation.

3D Bioprinted Organs--Bioengineered Organs Initiative at Carnegie Mellon University--Adam W. Feinberg, PhD

Nov 26, 2018 25:14

Description:

Organ failure is the ultimate cause of almost every death, and while organ transplantation can be a successful option, the need for organs significantly outweighs the supply. For the past 50 years or so, efforts have been focused on immunosuppression strategies and the development of mechanical devices capable of mimicking the function of biological organs and processes. However, even when available, these solutions aren't permanent or without the risk of complication. Now there's a new solution in the works, one with a lot more promise: bioengineered organs.


As an associate professor and member of both the Next Manufacturing Center and Bioengineered Organs Initiative at Carnegie Mellon University, Adam W. Feinberg joins the podcast to discuss how living cells and tissue components can be designed for implantation into the human body, allowing for tissue regeneration with the use of the body's own cells. Though it'll still take years to get there, the grand vision is to 3D bioprint partial or entire organs for transplant, which is a technology that's recently received funding from the FDA. 


Tune in to learn more about the current projects Dr. Feinberg and his team are working on, the successes they've already had, and the challenges they plan to overcome. Keep up to date on the latest developments at regenerativebiomaterials.com and engineering.cmu.edu/organs/index.html.

Great Expectations–Doron Pinhas, Chief Technology Officer of Continuity Software – How Businesses Can Safeguard Their IT Infrastructure, Protect Against Data Loss, and Meet Customer Expectations

Nov 26, 2018 23:26

Description:

Doron Pinhas, the visionary chief technology officer of Continuity Software (continuitysoftware.com), provides a detailed overview of the constantly evolving IT world and explains why businesses and entities need to ensure that their computing services function properly 24/7. For in today’s demanding tech world, people have high expectations and accept no excuses.


Since 2005, Pinhas has helped lead Continuity Software as its innovative CTO. Pinhas has more than 17 years of extensive experience in the future-forward, exciting areas of data and storage management, operating system design and development, real-time applications, and open system and networking architecture definition. Notable past experience on his impressive resume includes significant time as chief operating officer at Xpert Integrated Systems LTD., a leading Israeli SI. While at Xpert Integrated Systems LTD., Pinhas was instrumental in the development and formation of the Business Continuity Solutions division. Additionally, Pinhas is a veteran of the Israeli Defense Force where for 10 years he served as senior product developer and system architect.

Pinhas discusses Continuity Software’s mission: to help large enterprises provide 24/7 computing services. The company is comprised of a team of IT infrastructure and data protection experts who have the essential skills to help companies prevent unplanned IT outages across their entire IT infrastructure, including high availability, cloud, and disaster recovery environments.


Pinhas details the specifics of computing services, and the problems enterprises and companies face. With over 400 clients worldwide, all of which are Fortune 500, or equivalent, it’s clear that Pinhas and his team are providing value. He recounts how large entities have literally tens of thousands to hundreds of thousands of servers globally, and how it is becoming more and more challenging for them to keep up and maintain their services as they grow exponentially. Continuity Software is a proven leader in IT Resilience & Service Availability Assurance. Their award-winning solution enables IT teams to take control, and prevent infrastructure outages and detrimental data loss incidents. Getting ahead of the curve in regard to early, active detection of IT resiliency risks allows enterprises/companies, etc. to mitigate their exposed risk via remediation of configuration errors and deviations from policies— before the problems become problems, and before they become potentially costly issues.


Pinhas provides examples of many companies’ services, outages, etc. that can be devastating problems in a 24/7 demand society. As people and customers in general are more connected, Pinhas explains that service delays and outages are simply no longer acceptable. Today, a large volume of social media complaints can sometimes even elicit direct comments from a CEO, also via social media, to explain, apologize, etc; whereas in our recent past not so many years ago, as a society, we were much more forgiving of these issues. Those days are long gone.


With millions of moving parts and thousands of servers, Pinhas explains that testing and redundancy in IT is extremely involved and important. He outlines a handful of the types of problems that could arise due to failures and system errors, as well as power outages, etc. However, according to Pinhas, there are many ways to intelligently circumvent these failures by improving resiliency and redundancy every step of the way in the entire system, and Pinhas’s team works to help clients modernize their IT systems. From server updates to software upgrades, and so much more, Pinhas explains that although the problems are complex, they are not insurmountable. With proper management, it is entirely possible to maintain order and control quality.

The Rise of Data-Driven Societies and the Importance of an Interdisciplinary Approach—Philip E. Bourne, PhD—Stephenson Chair of Data Science and Director of Data Science Institute, University of Virginia

Nov 26, 2018 29:56

Description:

By combining the knowledge, tools, and approaches of computer science, engineering, and environmental studies, several students at the Data Science Institute at the University of Virginia are implementing drones in the collection of geospatial data involving ozone levels across the Blue Ridge Mountains. This is just one example of the practical applications of interdisciplinary studies, and the nature of the work being led by Philip E. Bourne, who serves as Stephenson Chair of Data Science, Director of the Data Science Institute, and professor of biomedical engineering at the University of Virginia.


Intrigued by the development of data science and its increasing number of important applications in modern society, Dr. Bourne runs an institute that thrives off of the benefits of interdisciplinary work and carries out projects in the fields of digital humanities, social sciences, finance, transportation, environmental studies, biomedicine, and engineering.


Dr. Bourne discusses a variety of exciting topics, including aspects of evolutionary computation, what distinguishes data science from computer science, ethics associated with the use of data, the connection between the study of proteins and precision medicine, and how an analysis of electronic health record and DMV data could lead to more accurate, potentially life-saving interventions in trauma surgery.


Tune in for the full conversation and reach out with questions via email at peb6a@virginia.edu. 

Bringing Your Food Options into the Third Dimension—Alper Guler—Kabaq

Nov 26, 2018 24:36

Description:

We’ve all been there: wrestling with that conundrum of what to order off the menu, and feeling unable to decide which sounds the best while trying to visualize the options. Wouldn’t it be great if we could just see the options right there on the table before us, prior to ordering? Now we can, and Kabaq is making it happen.


Established just two years ago by Alper Guler, Kabaq is a company that’s putting to use what so many major tech companies are investing in to enrich our lives: augmented and virtual reality technology. Realistic, actual-size depictions of various food items can now be visualized in 3D with the use of a tablet or your personal phone by scanning item-specific codes through social media platforms such as Snapchat and Facebook.


“We believe the next generation content is 3D...and we are creating the next generation content for food,” says Guler. But this content includes more than just an image of the food, he explains; Kabaq is taking it a step further by augmenting the space surrounding the 3D preview with stories and information about the food and the way in which it was sourced.


Kabaq is already working with 150 restaurants and is growing in popularity as positive feedback continues to flow in. Interested in checking it out for yourself? Hit play and visit kabaq.io to learn more. 

Simplifying the Distribution of High-Quality Benefits for Tens of Thousands of Employees--Peter Marcia--YouDecide

Nov 26, 2018 19:34

Description:

It's something that many large employers struggle with: the organized distribution of benefits to thousands of employees. While there may be a benefits strategy in place and hundreds or even thousands of different employee offerings, far too many employers keep these benefits siloed within different administrative systems, with no efficient way to organize or communicate the distribution of them. 


This is where YouDecide can help, a consulting technology and voluntary benefits outsourcing firm that organizes and aggregates employer benefit offerings, providing employees with large discounts on a variety of insurances, including auto, pet, legal, accident, life, disability, and long-term care. It’s a win-win result: employees save money on high-quality, necessary benefits, and employers gain a level of consistency and streamlined communication in the distribution of high-value benefits. 


Peter Marcia is the CEO of YouDecide and joins the podcast to discuss the ins and out of the services they provide, the primary challenges faced by large employers, and how changes in the healthcare space over the past several years have enhanced the growth and success of his firm. Hit play for the full conversation and 


visit youdecide.com to learn more

Cancer Cure – Jane McLelland, Noted Cancer-Starving Diet, Drug, and Supplement Expert; Author, How to Starve Cancer – Strategies to Combat Cancer Via Diet, Supplements, and Low-Toxicity Drug Treatment

Nov 20, 2018 40:51

Description:

Jane McLelland, physiotherapist, alternative cancer treatment expert, and author of How to Starve Cancer expounds upon the wrong turns that many people, unfortunately, take when they set out to fight their cancer. She provides a thorough and extremely important overview of the steps that anyone can take to dramatically improve their chances for survival when faced with a dire diagnosis.


Cancer survivor, Jane McLelland, talks about her background as a physiotherapist and her diagnosis back in 1994 with cervical cancer. McLelland tried all the traditional cancer treatment drugs and methods but made no significant progress. She recounts that it was not until her mother died of secondary breast cancer just two years later that she began to dig into the science of metabolism and get to the root of what was really keeping cancer alive and thriving. She states that when her own cancer moved to her lungs and she advanced to stage four cancer, that her time was considered to be limited, and thus she accelerated her research to find a solution. And as more chemotherapy was not going to help, she knew it was time to try another approach entirely. She discusses some of her research and many of the cancer-fighting regimens she put into place, such as intravenous vitamin C infusion, which some research has shown to be very effective at blocking glycolysis, the metabolic pathway that cancer cells use to thrive. 


McLelland’s groundbreaking book, How to Starve Cancer, is an incredible testament to the power of the human spirit. In her book, McLelland breaks down the steps she took to literally starve her cancer of the elements it needed to prosper. McLelland discusses her long journey back to health and the many crucial topics her book covers such as the varying fuel pipelines that must be blocked for each type of cancer. She talks about supplements that can be added to accelerate the cancer fight, and the low-toxicity drugs that exist to fight cancer, many of which have been all but forgotten as researchers tout the newer ‘game changers’ and put all their eggs in that basket.


McLelland details the nature of cancer and how it exhibits incredible determination to flourish, for example, if cancer cells are no longer able to fuel on sugar, they will literally rewire themselves to survive on alternative fuel sources to create more protein and thus create more daughter cells. By preventing the cancer cells from gathering more fuel, patients can put the brakes on the system. McLelland discusses the sections of her book that provide specific detail on proteins, fats, glucose and the cancer cell’s fuel supplies that must be cut off in order to fight the disease. She provides very detailed information on the science behind the metabolic cocktail options that individuals can tailor to their specific cancer. McLelland’s book will help people to find the key metabolic pathways they need to understand in order to fight their cancer. Using herself as a testing laboratory, she experimented to find the best drugs and supplements to starve her own cancer and has gathered this information into a map of sorts that individuals can use to guide their own journey and fight. 


McLelland talks about the importance of drugs in the fight against cancer. She states that diet is crucial, but diet alone rarely can achieve the best results, and that it is a combination of diet, supplements, and low-toxicity drugs that provide the proper combination of ingredients. She goes into depth about protein, fat, and carbs, the three essential elements of the human diet. She explains the ways that cancer cells use each to further their survival and the production of daughter cells. 


She discusses how the pharmaceutical industry’s testing process is flawed, in that it works on one solution at a time, which is a slow process that needs to be accelerated. She states that her cocktail approach is a means that individuals can begin to implement now, to fight their individual cancers. Additionally, she provides information on the alternative drugs that can be used to fight cancer. These drugs are considered to be ‘alternative’ because they are drugs that were created for different diseases and conditions other than cancer, but McLelland states they can be used as part of a successful cocktail to combat cancer. McLelland talks about the keys to combatting the disease, rethinking the traditional methods somewhat and using all the existing methods together in a more intelligent manner. She mentions that reducing the traditional chemotherapy to much lower doses actually stimulates the immune system, which would not happen with the high doses that traditional cancer treatment recommends in most situations. 


McLelland states that the wealth of research she offers in her social media and in her book provides critical information that is backed by science and evidence. McLelland’s method as described in her book takes on the common misconceptions that exist in the theories of cancer treatment. The book delves into the mystery of cancer and answers important questions that can elevate anyone to a higher level of understanding as they forge ahead on their own journey to beat cancer. 


Remarkably, McLelland states that in her opinion there is almost no cancer, even at stage four, that cannot be reversed with the proper alternative treatment and protocols. Hope exists!

Jodi Goldstein, Executive Director of Harvard Innovation Labs – Solving Real World Problems Through Expanded Innovation and Technology Utilization

Nov 20, 2018 32:28

Description:

Jodi Goldstein, the Bruce and Bridgitt Evans Executive Director of Harvard Innovation Labs (<a href="http://innovationlabs.harvard.edu">innovationlabs.harvard.edu</a>), delivers an overview of the innovation marketplace and how students and entrepreneurs can utilize testing and technology to advance their ideas and solve real-world problems. Harvard Innovation Labs includes the Harvard i-lab, the Harvard Launch Lab for alumni, and the Pagliuca Harvard Life Lab for alumni, faculty, and student-focused life science ventures. 


Goldstein has over 20 years experience as a formidable startup executive, an enterprising co-founder, and investor. Her specific expertise in consumer and e-commerce, mobile, and luxury goods businesses, combined with her strong management skills have allowed her to carry many projects and initiatives to new heights of achievement. Notably, Goldstein had leadership roles in venture-backed startups such as iMarket (that was later successfully sold to D&B), PlanetAll (that was built up then acquired by Amazon for $100M+), as well as Mobicious, Send.com, and Hoteluxury.com. 


Goldstein discusses the many companies and projects she has worked with and led to success. And she outlines some of the potential pitfalls that entrepreneurs can fall prey to. Goldstein explains that entrepreneurs and innovators need to test their early ideas in regard to practicality and validation, to assess their relative value in the marketplace. She outlines the value that industry leaders can bring to their respective companies by utilizing advanced technologies such as artificial intelligence, virtual augmented reality, and blockchain.


Harvard Innovation Labs’ mission states that knowledge is certainly the engine of innovation, but the combination of connection and collaboration is the critical fuel needed for forward progress. By unlocking unrealized value, Harvard Innovation Labs can have a tremendous impact on markets, the world, and the individuals who utilize the valuable input and services they provide. Goldstein’s work involves helping students and entrepreneurs take their ideas and apply them to solve real-world problems.


Goldstein discusses the diverse areas in which Harvard Innovation Labs provides expertise and assistance. She provides an overview of their extensive ecosystem in terms of what it offers. For example, the i-lab is a full-service space for currently enrolled Harvard students who are interested in pursuing innovation and entrepreneurship opportunities. Launch Lab X is their innovative new accelerator inside the i-lab that is designed for eligible Harvard alumni who are already pushing forward their promising early-stage startup ventures. And the Pagliuca Harvard Life Lab is for Harvard students and faculty, as well as alumni who are working on important life sciences and biotech startups and ventures. From medical to advanced technology, Goldstein describes how their innovation techniques and methods have helped creators and entrepreneurs walk their own unique path to breakthroughs and successes.


Goldstein holds an MBA from Harvard and a BS in International Business from the University of Vermont. She has been featured in Fast Company and The Boston Globe and is a regular contributor to Fortune as part of its Entrepreneur Insider network. Her broad range of skills and experience has prepared her for the challenges of leading Harvard Innovation Labs to continued success as they engage with the global community. And she is motivated to implement new strategic initiatives that can potentially expand their student and alumni range, presence, and impact while simultaneously serving as the chief liaison to the organization’s prominent stakeholders, as well as the national and international community.


Bypassing Surgery: An Oral Pill for the Treatment of Morbid Obesity—Hasan Celiker—Xeno Biosciences

Nov 15, 2018 31:11

Description:

Gastric bypass surgery is the most effective form of treatment for morbid obesity and a familiar term to most of us, but until recently, the underlying mechanism that makes it so successful has been largely misunderstood. Most people—including health professionals—attribute the weight loss that follows from this surgery to reduced stomach size and therefore reduced food intake and malabsorption, but the evidence is pointing elsewhere: to the changes in gut microbiota that occur after the surgery.


Hasan Celiker is the founder and chief executive officer of Xeno Biosciences, a company that’s using what they’ve learned about the effectiveness of gastric bypass surgery to develop an alternative and significantly less invasive form of treatment for obesity: an oral pill that mimics the changes in gut microbiota that occur after the surgery, allowing for weight loss and a significant reduction in conditions associated with obesity, such as diabetes and fatty liver disease.


Celiker delves into the details of digestive mechanisms, the differences between aerobic and anaerobic bacteria and the role of each in the microbiome, how and where in the body Xeno Bioscience’s pill takes effect, and the metabolic changes brought about by both the pill and the surgery. Hit play and visit xenobiosciences.com to learn more. 


Next Generation Antivirus Software—Adam Kujawa—Malwarebytes

Nov 15, 2018 36:21

Description:

Criminal cyber activity has increased dramatically over the past 10 years, leading to the existence of more malware than ever before. With so many hacker forums and cyber criminals offering their services on the dark web, committing cybercrimes no longer requires an extensive amount of knowledge or experience; you just need to know who to talk to. 


Having spent over 14 years working in the field of cybersecurity, Adam Kujawa has witnessed the evolution of cybercrime. While it might seem like he’s seen it all, he’s the first to admit that the landscape is constantly changing, requiring cybersecurity measures to remain a step ahead of the cyber criminals. He joins the podcast today to discuss the work he’s doing as the director of malware intelligence at Malwarebytes, a security solution company developing layered defense software for individual consumers and enterprises with the ultimate goal of creating a malware-free existence for the world.


Tune in for an informative and insightful conversation about the current types of malware, ransomware, and cyber-attacks, sandbox security mechanisms, security countermeasures carried out by criminals, and the recent increase in cyber-attacks in the business arena. 


Learn more and check out free trial services at malwarebytes.com.  

Brain Breakthrough – Cavin Balaster, Author, and Founder of Feed a Brain, and Adventures in Brain Injury – Neurology, Nutrition, and the Specific Dietary Changes That Can Optimize Brain Function and Repair The Brain

Nov 14, 2018 49:50

Description:

Cavin Balaster, founder of Feed a Brain (<a href="http://feedabrain.com">feedabrain.com</a>) and Adventures in Brain Injury (adventuresinbraininjury.com), author, and sought-after speaker, delivers an informative and important discussion on brain function and the nutritional protocol that can deliver dramatic results.


Cavin Balaster made a miraculous recovery from an accident that could have easily taken his life instantly. In 2011, he survived a two-story fall and was comatose for twelve days. Balaster was diagnosed with a diffuse axonal injury (DAI) and his chances for recovery were not good, bleak actually, at less than 10%. Emergency medicine and the work of many skilled, truly outstanding healthcare professionals and specialists saved his life, without a doubt. Balaster acknowledges that he would absolutely be dead if it were not for their incredible work over a long period comprised of many crucial moments in his recovery. But after he began to wake from the severe brain fog, and recover somewhat from the memory loss, double vision, infections, etc. when he was able to begin doing some research on his own, he started on a mission, a goal to take back his life to the best of his ability. He states that once he was cognizant of his predicament and the gravity of it, he felt he was faced with a choice: to wallow in despair considering the impact of his injury or consider it to be an adventure. He chose the latter. 


Balaster recounts the early months of his life after the fall and subsequent severe brain injury. As he describes, the entire ordeal, as we can only imagine, was overwhelming to say the least. He talks about the extreme, and frightening, brain fog that he experienced early on and how he actually had no memory of what happened and no way to understand where he was or who the white lab coat people were. His brain fog was so intense that he imagined he might have even been kidnapped and the lab coat people were using his body to test and experiment on. Clearly, it was not a good time for Balaster. But slowly, his brain fog began to clear so he could begin to understand where he was, and what was happening to him.


After defying death through the help of his incredibly wonderful team of intelligent and supportive healthcare providers, and waking from the coma, Balaster dug deep into functional nutrition, functional neurology, neuro optometry (developmental optometry), physical and occupational therapy, and other targeted therapies. And it is these methods and practices that he attributes to his incredible recovery, at such an accelerated pace. Balaster talks about his first discovery of the nutritional connection, and how his nutritional protocol was restoring his clarity. And he describes the technical aspects of how the intestinal process is coordinated with the brain. Balaster discusses his hunger for education on the various subjects that were affecting his life and recovery. He began taking online courses at multiple universities to further understand how the brain works, and how it is fueled—neurometabolism. He details some of the many and various nutritional supplements to his diet from bone broth, to licorice, to L-glutamine, as well as fruits and vegetables, etc., and how he began to see incredible improvements right away. Balaster discusses the details in his book, covering ketogenic metabolism, color charts for fruits and vegetables, and the carbohydrate ratings of foods. 


Balaster documented his process to neuro-rehabilitation in an attempt to more fully understand and heal his body and brain. He discusses his blog, Adventures in Brain Injury, and the international attention he received from his postings and research. Balaster talks about the work he has done with clients who have severe injuries, and the nutritional coaching he provides to the patients and their doctors that has led to many remarkable changes and improvements. As Balaster recounts, his work with patients is tremendously rewarding. 


As the author of How to Feed a Brain: Nutrition for Optimal Brain Function and Repair and as a successful podcast host on the related subjects, Balaster has now devoted his life to helping others who are struggling with health issues, sometimes very severe ones as his was. Through Balaster’s journey he has gained incredible knowledge regarding the optimization of brain function and he seeks to share his experiences, information, training, and services with the community.

Financial Fitness – Scott Eaton, Chief Executive Officer at Algomi – Staying Ahead of the Game in Financial Markets Via the Utilization of Aggregated Complex Data That Increases Efficiency

Nov 14, 2018 36:03

Description:

Scott Eaton, chief executive officer at Algomi (<a href="http://algomi.com">algomi.com</a>), provides an overview of the complexity of financial markets and how traders and investors need aggregated complex financial data to capitalize on and secure their interests.


Eaton is an experienced executive who has helmed many top-tier institutions. Some notable point on his extensive resume include: chief operating officer of MarketAxess Europe, managing director at Unicredit Bank AG, as well as executive managing director at BroadStreet Group.


As Eaton states, Algomi is a software company that provides technology to financial markets. Algomi delivers information-matching solutions for the optimization of fixed-income liquidity. The company is backed by investments from prominent industry leaders such as Euronext, Lakestar, AllianceBernstein, and S&amp;P Global. Algomi’s team is international and maintains offices in New York, London, and Hong Kong.


The Algomi platform can assist business leaders to improve their workflow and liquidity via data aggregation, pre-trade information analysis, and of course execution facilitation. Eaton expounds upon the ways that Algomi brings infrastructure to some of the world’s largest fixed-income participants, helping them to turn complex data into actionable knowledge.


Eaton discusses Algomi ALFA, their innovative fixed-income data aggregation and market surveillance tool that aggregates liquidity data from all the major electronic venues, messaging platforms, and dealer inventory feeds, and thus provides easier access, and an opportunity to see the big picture with more detail. Traders can apply filters and see the data that is important to them, making their time more efficient and potentially more successful. By finding the liquidity more easily, Eaton states that Algomi ALFA benefits both buyer and seller, assisting with the execution of trades.


The financial markets expert delves into the many ways that buy side traders can utilize their platform. He details the processes involved with trading, specifically outlining the methods used when dealing with bonds, and he explains how bond market liquidity has been impacted, post-financial crisis. Further he talks about the issuance of corporate bonds and discusses schedules versus discreet needs, investor interest, borrower cost and more, in regard to timing and issuance. He discusses strategies investors and traders can utilize when making bond decisions, and how the aggregate data directly can impact the decisions they will make.


Eaton discusses the innovations happening at Algomi in regard to data feeds, as well as their extensive work with custodians and custody data to help facilitate asset management. Through Algomi’s understanding of financial markets and experience of workflow development, Eaton’s team collaborates with clients and third party providers to birth new ideas and products that greatly facilitate market function, and bring infrastructure to some of thargest fixed-income participants in the world.

Transforming the Workforce Management Landscape—Himanshu Misra—Branch

Nov 13, 2018 36:27

Description:

You might already be familiar with the process of taking pictures of your work schedule each week, checking it repeatedly to make sure you don’t miss a shift, and tracking down all your coworkers’ phone numbers when you need coverage at the last minute. This is not only a hassle for hourly employees, but it’s an inefficient way of managing shifts in general and makes it more likely for a company to find itself unexpectedly understaffed. With nearly 60 percent of today’s workforce comprised of hourly workers and having worked as one himself, Himanshu Misra recognized a need for change; as a senior data scientist for Branch, that’s exactly what he’s trying to implement.


Branch is a mobile-first technology platform that allows hourly employees to easily and digitally access their schedules, be notified of changes to their schedules in real time, communicate with their coworkers, submit requests for time off at the tap of a button, and pick up shifts to expand their earning potential. At the same time, Branch is helping enterprise customers attract and retain the best hourly employees and providing them with a time-saving tool for efficient shift management. By developing demand prediction models based on historical and real-time data and machine learning algorithms, Branch customers can avoid all of the consequences of improper staffing and unsatisfied staff.  


Branch already has customers in a variety of industries, including banking, hospitality, healthcare, retail, and travel, and are currently holding a number of pilots with new companies. Tune in for all the details, including what’s on the horizon for Branch. 


Visit<a href="http://branchmessenger.com"> branchmessenger.com</a> to learn more. 

Born This Way – Jeremy Born, Founder and CEO at CoinGenius – Using Aggregated Information and Advanced Tools to Get Ahead As Cryptocurrency Evolution Becomes Revolution

Nov 12, 2018 26:39

Description:

Jeremy Born, founder, and CEO at CoinGenius (coingenius.ai), delivers an informative overview of the current state of cryptocurrency intelligence and the developing tools that allow for a deeper understanding of the changing digital financial markets.


Born is a serious blockchain enthusiast and passionate digital strategist. He is an experienced professional in the technology space with a specific interest in leveraging AI and machine learning to solve complex business problems, as well as predicting outcomes of alternative assets such as bitcoin. Born’s experience before founding CoinGenius was in the various blockchain, cryptocurrency, and artificial intelligence companies such as YINC, which focuses on cryptocurrency and blockchain technology service providers, and JABB Interactive where he served as their executive director. During his tenure as senior managing consultant at Brandify Labs, Born furthered his work in branding and customer services as they relate to cognitive, artificial intelligence, machine learning, natural language processing, and blockchain. He holds an MBA from Pepperdine’s Graziadio Business School and received his BS in business administration and management from Chapman University.


Born discusses his background in trading and how he had passed crypto by for a while, but as he began to dig deeper he became extremely interested. Once he took the leap and fully invested his time, and later money, he found that the tools and information available was seriously insufficient and woefully inept. He wanted to apply all of his knowledge in AI and machine learning to his new passion to fully understand what was contributing to the volatility of the market in this exciting, burgeoning digital area. As he recounts, the market changes so quickly in this space that insufficient data and the need to research could cause someone to miss a great opportunity—the need was apparent: information needed to be aggregated, and new tools were a necessity.


The artificial intelligence and financial markets expert discusses the types of events that trigger volatility and market fluctuation, and he acknowledges that the market is still highly unregulated. Thus, access to the constantly incoming information is paramount. Born’s way was a new way of looking at data that allowed for smarter, quicker decisions to be made and thus CoinGenius was born to fill the void. 


CoinGenius is an AI-powered cryptocurrency intelligence engine specifically built to empower traders with fast, real-time data needed to make intelligent investment decisions that can yield results. Born underscores that they do not make recommendations, but they do arm people with quality information. The platform allows for smarter trades and utilizes analysis, deep fraud detection, and real-time trade alerts. As Born’s company acknowledges, investing in cryptocurrency can be challenging but with the proper tools, the trading options are better. At the core of the market, every digital asset and coin is greatly impacted by, and produces, a large amount of internal and external signals. Having the proper tools can help to order the volume of information so traders can home in on what’s important. 


Born gives an overview of where his team is in the process toward release of their platform and the steps they have already completed to make the full launch in early 2019. Born discusses that first they plan to do a mobile release, but other options will be coming. As many apps are on the way in this market, it can be overwhelming, but Born stresses that none of them are truly bringing everything together under one platform, that also covers multiple asset classes as CoinGenius does. 

The Most Healthful Diet, or an Exercise in Irrational Exuberance--Valter D. Longo, PhD--Biogerontologist, Cell Biologist, and Author of The Longevity Diet

Nov 9, 2018 34:53

Description:

The ketogenic diet, intermittent fasting, whether or not you should skip that first meal of the day...you’ve probably heard a lot of arguments for and against each, so how do you know what’s “right”? What will provide YOU with healthful longevity? Valter D. Longo is a biogerontologist, cell biologist, and author of several books, the latest of which is The Longevity Diet. He joins the podcast to discuss his views on these issues and shed light on some of the main arguments in his book, each of which is based on the scientific evidence that’s available today. 


The Longevity Diet is divided into two sections: the first utilizes an approach that’s based in part on findings of epidemiological and clinical studies to decide how best to eat on a daily basis, and the second discusses the benefits of the fasting mimicking diet. He’s a proponent of diets rich in legumes and vegetables, 12-hour daily fasts, and making time for breakfast each morning.


While he admits that the ketogenic diet may benefit some individuals with particular health issues or diseases, he references a Harvard study that followed 120 subjects over a 30-year span and drew conclusions about the long-term effects of high fat, high protein, low carb diets: significantly shorter lifespans, and higher rates of cancer and cardiovascular disease. He also discusses how daily fasts that exceed 12 hours lead to a mechanism by which the body essentially begins eating itself, and how the concept of “irrational exuberance” is largely at play in many people’s devotion to diet fads. 

Age-Defying Stem-Cell Infusions—Joshua Hare, MD—Longeveron

Nov 9, 2018 22:58

Description:

Ageing: it’s an inevitable part of life, it affects us all, and there’s just no way around it. Or is there? “Ageing is a major societal problem that we’re turning our attention to in the biotechnology industry as something that’s treatable...and that we can modify biologically to improve the health span of people in our country and worldwide,” says Dr. Joshua Hare, co-founder, and chief science officer at Longeveron. Founded four years ago after receiving a technology license from the University of Miami Interdisciplinary Stem Cell Institute, Longeveron is a biotech company bringing over 20 years of clinical research and 40 years of basic research to address the problem of ageing.


The team at Longeveron proposes that allogeneic mesenchymal stem cells can be used to treat ageing frailty, a condition that affects 50 percent of people over the age of 65. Dr. Hare discusses the evidence in support of his hypothesis, the regenerative and reparative potential of these stem cells, how to determine the best method of delivery, why ageing frailty is a condition that’s particularly likely to respond positively to these types of stem cells, roadblocks to the development of research in this field, and what he thinks will happen over the next few years.


Tune in for the full conversation, and visit longeveron.com to learn more. 

Regeneration Creation – Dr. Stuart Williams, Cell Biology Expert and Founder of Bioficial Organs – The Mind-boggling Science of Bioengineered Organs and Tissues, and the Future of Regenerative Medicine

Nov 8, 2018 32:48

Description:

Dr. Stuart Williams, founder of Bioficial Organs (cvregen.com), delivers an interesting overview of the future of bioengineered organs and tissues, and the medical advances that we are seeing daily. Williams has extensive experience in the areas of biomedical engineering, surgery, physiology, as well as materials science and engineering. He is the former director of research for the Department of Surgery at Jefferson Medical College, former faculty at the University of Arizona, and founder of the University of Arizona Biomedical Engineering Program. In 2007, Williams was appointed as the scientific director of the Cardiovascular Innovation Institute, a collaborative partnership between the University of Louisville and Jewish Hospital. Williams received a Ph.D. in cell biology from the University of Delaware and did his postdoctoral training in pathology at the Yale School of Medicine. His strong interest in medical devices and regenerative medicine paved the path toward his development and patent of one of the first methods to use fat-derived stem and regenerative cells for therapeutic use.


Dr. Williams discusses the Bioficial Organs Program and their work to create human tissues and organs for clinical therapeutics and in vitro drug efficacy and toxicity testing by utilizing a patient’s own cells. He gives a detailed overview of the fascinating process of creating organs and tissues from biological parts. As Williams explains the human body has at least eleven different types of organs and tissues, some that are extremely complex, but some that are simpler, that can be created via the Bioficial process. He explains how the complexity is often based in the number of specific cells that are used to perform functions. As he states, the liver and the kidney are perhaps more difficult to bioprint than other organs, but that parts of tissues, such as skin, are easier to tackle successfully in regard to regenerative medicine. He discusses work they are very excited about, including their active lab program to use 3D bioprinting to create an artificial pancreas, in order to produce insulin on demand in a patient. 


The biomedical engineering expert discusses specific organs that can regenerate, and those that cannot. Unfortunately, for example, the heart does not have cells within it that will repopulate a damaged area, but it may be possible to put organoids into a damaged part of the heart such that they may take up residence and begin to create a functional part. Williams discusses his extensive work focused on developing new and successful ways to remove patients’ cells and build new blood vessels from those cells that can be reinserted into the body. He cites examples of some specific work with patients that helped to advance the regenerative medicine field. 


Dr. Williams discusses their exciting new plan to move bioprinting to the international space station, which will allow them to avoid the effects of gravity that can adversely impact some of their work. He relates how the fetus is formed in amniotic fluid, and thus is somewhat defying gravity as it can move about freely in its environment. And this study of those conditions, in fact, creates more questions as well as answers to how growth happens regarding organs, and the conditions and mechanisms that are involved in that complex process. Further, he discusses the shapes of organs, and how it may not be necessary to recreate organs in the same shape in which they naturally occur in the body. Additionally, he muses about regeneration, and why some organs will regenerate, but others will not, and he states that he is very interested in studying all of these issues in detail to find the answers. 


Dr. Williams has authored more than 300 scientific publications and his work has generated 22 issued US patents with nearly countless patents pending. He’s the founder of six biotechnology companies and is a fellow of the American Heart Association as well as the American Institute of Medical and Biological Engineering.

Organic Meals with Doorstep Delivery for Preconception Pregnancy Postpartum Stages of Life Erica Mock twenty-fiveEIGHT

Nov 8, 2018 26:14

Description:

Most women who’ve been pregnant are familiar with the strong, sometimes strange food cravings that occur to them—cravings that might not always be for nutrient-dense, healthy, and unprocessed foods. As a mother herself, Erica Mock is all too familiar with the battle between satiating those cravings and eating healthy during pregnancy, but she has an interesting take on the matter, stating, “Our bodies have an incredible innate intelligence. I craved sushi every day, started supplementing high-quality omega-3 supplements, and the cravings went away…the body knows what it needs.”


And what does the body need before, during, and after pregnancy? High-quality, nutritious, individually-curtailed, and of course deliciously mouth-watering foods. This is exactly what Erica Mock set out to provide for women when she founded twenty-fiveEIGHT. Customers can simply visit the website to choose from several subsections and menu options, including foods that increase the volume and quality of breast milk, vegetarian foods, homemade black sesame almond milk, bone broths made from 100% pastured animals, a dairy-free chickpea noodle macaroni and “cheese” dish, and a flourless seed bread that’s excellent for digestion. All foods on the menu are organic and local, and Mock has been mindful enough to opt for the most sustainable packaging materials so you can feel good about your purchases.


The company is still in the beginning stages, with a launch party scheduled for just after the holidays this year. Tune in for all the details—including a sweet story that explains how she came up with the name of the company. Visit twenty-fiveeight.com to learn more. 

Investment Innovation – McLean Wilson, Co-Founder and Manager of Spark Invest – The Investment Platform that Brings Average Investors & Innovative Companies Together

Nov 8, 2018 28:25

Description:

McLean Wilson, co-founder, and manager of Spark Invest (<a href="http://sparkinvest.com">sparkinvest.com</a>) discusses the many new opportunities that exist in the marketplace for the average investor, and how his company is helping promising companies to take the next step to their success. Wilson is a seasoned alternative investment and asset-based lending expert. He has extensive experience in asset management and capital raises for alternative investments, as well as structured transactions, transactional operations, recourse and nonrecourse purchase agreements, negotiation, and management. Wilson’s knowledge of the aforementioned, along with his keen understanding of the underwriting processes and the elements of secured and unsecured transactions makes him exceptionally qualified to lead his team at Spark Invest.


Wilson’s considerable past accomplishments in business include his tenure as vice president of SouthStar Capital, an asset-based lender strategically focused on factoring. While at SouthStar, Wilson structured and funded many equipment leases and purchase order financing transactions. Other notable points on Wilson’s extensive resume include his work as an investment advisor with ING Financial Partners and Money Concepts Capital Corporation and Wilson’s focus was on financial planning, investment planning, and portfolio management. He holds a bachelor of science and a master of science in civil engineering from Clemson University and is a registered investment advisor representative.


Wilson explains that his company, Spark Invest, is an equity crowdfunding platform that provides an opportunity for average retail investors to invest in early-stage nonpublic companies that are poised for growth. He states that Spark Invest has higher expectations and qualifications for the start-ups and companies that are given an opportunity to exist on their platform. They typically need to have proof of concept, to have ideally already raised some capital, and have a good use for their capital. Simply having a ‘good idea’ is not enough for Spark Invest, as the Spark Invest team is comprised of many entrepreneurs who have extensive experience with starting companies, closings, and exit strategies, and understand what it takes for a company to launch and succeed. As Wilson acknowledges, they really don’t want companies on their platform that they would not personally feel great about investing in themselves. Wilson explains their vetting process and gives detail on the specifics they look at, such as audited financials, etc., to ensure that the companies who are given the opportunity to exist on the Spark Invest platform are quality, vetted, legitimate, and promising companies worthy of an investor’s time, and dollars.


In the past, these types of alternative investments in promising private companies were only available to qualified institutional investors, but thanks to a major change in securities law, these companies can now be owned by the public without the usual standard initial public offering, or IPO. This opportunity works well for new companies who have a great concept or product that has already had some success and are now looking to take on investors, but want to avoid the typical VC investor who might mandate that the entrepreneur become an employee of the VC upon taking in their investment dollars. Additionally, the platform is a unique opportunity for smaller investors to make investments in promising new companies that they typically have not had access to in the past. Thus, the platform can be beneficial to all parties involved. 


Wilson discusses some of the types of companies and ideas that they like to bring to their platform, as well as some that they don’t. He explains their marketing, and how they attract some of their most interesting companies. And he provides detailed information on the various investment platforms that exist and how Spark Invest takes a different view than some of their competitors, as they monitor the kinds of companies that come into the platform and prudently review their financials. While Spark Invest is interested in many types of companies, Wilson states that they are certainly drawn to practical companies that are solving problems via incredibly innovative ideas. Through Spark Invest, intelligent retail investors can invest in companies that may someday yield higher returns than traditional platforms are able to offer. And the platform allows investors to choose the level of risk that they are comfortable with.

The Melding of 3D Printing and Mainstream Manufacturing—Dr. Jason Jones—Hybrid Manufacturing Technologies

Nov 8, 2018 16:03

Description:

As it currently stands, the only way of making metal parts in small and medium volumes is through the use of CNC machines, which is a fast and accurate yet wasteful method. In fact, 90-95 percent of the metal blocks purchased for this purpose are ultimately thrown out. 


3D printing (also known as additive manufacturing), on the other hand, allows for a less wasteful process and extremely geometrically flexible products, but cannot produce the necessary surface finishes. Until now, there’s been no way to use the most beneficial aspects of each process by combining them into one system. This is where Hybrid Manufacturing Technologies comes in, a company that has introduced the first-ever commercial system that integrates the best of both worlds.


As the CEO of Hybrid Manufacturing Technologies, Dr. Jason Jones offers a detailed explanation as to how exactly their machine works, gives examples of several interesting use cases and argues that the system itself represents the ability to overcome the biggest hurdle that faces 3D printing today. “Additive [manufacturing] has been developed in isolation from mainstream manufacturing...by combining it with CNC machines, there’s automatic uptake into mainstream manufacturing, which is exciting,” says Dr. Jones.


Press play to hear the full conversation, and visit hybridmanutech.com to learn more. 

A New Prospect Sustainably Feeding the Globe Using Agricultural Robots—Girish Chowdhary—Agricultural and Biological Engineering Department, University of Illinois

Nov 8, 2018 32:35

Description:

Right now in today’s vast agricultural fields, teams of semi-autonomous, low-cost, and intelligent robots are scanning fields of corn and providing measurements that will allow breeders to better characterize the environment and breed better seeds. The next task will be for these robots to autonomously collect more complex information that will allow for earlier detection of plant diseases and nutritional deficiencies. 


Drones are commonly used for the collection of data in large-scale farming today, but the robots that are being designed in the Agricultural and Biological Engineering Department at the University of Illinois can detect what’s unobservable by drones by harnessing a higher level of resolution that can only be achieved from working under the canopy. What’s the third task planned for these robots? Acts of manipulation, such as weeding and pruning, which will be unprecedented.  


As an assistant professor working on this project, Girish Chowdhary discusses how the deployment and development of these robots will cause us to rethink the way we do agriculture and allow for the globe to be fed in a sustainable way from small gardens with multiple plants. However, he also discusses some of the biggest challenges, which involve the varying and unpredictable nature of outdoor environments. Will robots be able to learn to operate intelligently enough to mitigate uncertainty and unforeseen changes?


Tune in for the full discussion, reach out to Girish via email at girishc@illinois.edu, and visit <a href="http://daslab.illinois.edu">daslab.illinois.edu</a> for more information. 

Ketogenic Life – Rachel Burke, Ketogenic Enthusiast and Founder of Aussie Keto Queen – How a Ketogenic Diet & Lifestyle Can Improve Health, Assist with Weight Loss, and Increase Energy

Nov 7, 2018 24:15

Description:

Rachel Burke, the ketogenic enthusiast and founder of Aussie Keto Queen (aussieketoqueen.com), discusses the ketogenic diet and lifestyle. Burke’s journey to better health was a long one, as she spent many of her earlier years battling weight, feeling uncomfortable with her body, and being unhappy about it all. From the tender age of just 10 years old, she began weighing herself and struggling with her weight issue. She spent a significant amount of time, unfortunately, experimenting with this diet plan and that diet plan, magic diet shakes and pills that really weren’t so magical, along with massive amounts of exercise, but nothing seemed to work for the long haul. It was all of these years of frustration that finally brought her to nutritional ketosis—which was a game changer. After she made the decision and stuck with it, keto transformed her life. Burke describes how she reached her goal weight even sooner than she expected, and how she has more energy than ever before. In addition, when checking with her doctors through the process she found that the ketogenic lifestyle was not only helping her to lose weight but that her overall health markers were improving too. Burke is living proof that you are what you eat.


Burke recounts how she was so satisfied with her results that she wanted to share all that she had learned, through her exhaustive research, with everyone. She began posting her favorite recipes and helpful tips online, which led to the site she currently inhabits, aussieketoqueen.com, which is full of helpful information for those who want to find their own success. With tens of thousands of visitors to her site on a regular basis, it’s clear that there is a keen interest in the ketogenic diet and lifestyle. She discusses the importance of mindset. As Burke states, changing one’s mindset is perhaps the most important step, and it is not something that happens for everyone immediately. For some, it takes time, a gradual change, but committing to the nutritional life change pays off in the end for those who are ready to make a difference in their diet and health. 


Burke talks about how, in Australia, that doctors and nutritionists are now beginning to advise patients and clients about the possible benefits of switching to a ketogenic diet. She discusses the options people have when eating out and trying to stay focused on their ketogenic diet. And she expects that perceptions will continue to change as ketogenic options become more widely offered everywhere. 


The nutrition and health advocate states that it is really all about finding what works for you as an individual considering your own body, lifestyle, work, and timetable, etc. Burke provides an overview of her site’s recipes, the types of foods she prefers, and also what she recommends. From the basic meat and veggie options to sweeter options, her website offers something for every keto-conscious eater. And while she does not recommend many sweets, she includes some sweets recipes as the keto community appreciates a full range of food options. However, as Burke states, when people really take on the keto nutrition lifestyle and are eating ketogenic regularly, they often find their taste buds change a bit and begin to taste the natural sweetness in foods more obviously. Some have found that this effect is so pronounced that they no longer crave traditional sweets. 


Burke discusses her future plans for ketogenic consulting and what she is excited about. She states that the ketogenic lifestyle’s impact on her friends and family has been so profound that she is determined to bring all that she has learned to a wider audience, and help everyone reach their personal goals for health and wellness.

Benjamin Freedman--Freedman Lab, University of Washington--Growing Organoid Models for Studying the Most Common Kidney Diseases

Nov 6, 2018 25:54

Description:

An estimated 10 percent of all people have some level of kidney disease--a disease that’s most commonly associated with diabetes and high blood pressure. The numbers are only growing, but much of the research has been limited in the sense that the progression of kidney diseases in humans is difficult to track. 


For example, polycystic kidney disease--a very common one that’s genetic in nature and affects millions of people--is usually diagnosed in the later stages, only once the changes can be visualized via ultrasonographic imaging. At that point, many people are faced with just two options: dialysis, or a kidney transplant. But the team at the University of Washington’s Freedman Lab are doing something that’s never been done before: using pluripotent stem cells to grow kidney organoids which have many of the same properties and characteristics as human kidneys in order to create the genetic mutations that are seen in this disease and to study the origination and progression of it. 


The creation of organoids aren’t just limited to kidneys though; given how powerful pluripotent stem cells are, they can be developed into any organ in the body. Just imagine being able to conduct experiments on miniature brain and liver organoids, for example. In the long run, this technology could result in the creation of more complex structures with the capability of replacing functional human organs altogether. 


Benjamin Freedman is the head of the Freedman Lab and offers an in-depth discussion on the observations his team has made so far, and hypotheses as to what exactly is at play in the development and progression of common kidney diseases. 


Tune in for a compelling conversation and visit <a href="http://freedmanlab.com">freedmanlab.com</a> to learn more. 

Angela M. Poff—Cancer Biologist and Metabolic Health Summit Cofounder— Globalizing the Conversation about Ketogenic Diets and Therapies

Nov 5, 2018 45:41

Description:

Just a few years ago, Angela M. Poff noticed that a lot of leading scientists and clinicians were studying ketosis and metabolic therapies for different diseases, but weren’t getting together to share their ideas and have productive conversations; this all changed when she decided to found the Metabolic Health Summit in 2015, which now serves as a hub for those who want to work together to develop ideas and move new information in the field to the next level.


The goal of the 2019 Metabolic Health Summit is to foster a global conversation about the ketogenic diet and how to implement it in the real world and will feature several personal stories from those whose lives have been affected by the adoption of the keto lifestyle. The conference is not just for scientists this year; it’s for everyone. The best scientists and clinicians will lead sessions dedicated to different uses of the ketogenic diet, including for Alzheimer’s, mental health, obesity, migraines, cancer, and longevity.


Poff also works as a research scientist at the University of South Florida, where she focuses primarily on the effects of metabolic therapies on cancer. In particular, she studies how the ketogenic diet affects cancer models, the role of exogenous ketones in the development of cancer, and the role of metabolic targeted agents, such as dichloroacetate and metformin. Poff discusses a variety of topics, including how and why hyperbaric oxygen therapy can be successful in treating tumors and the biggest roadblock to continued research in the field.


If you or a loved one is dealing with cancer, Poff suggests visiting clinicaltrials.gov and working closely with your oncologist. 


Visit <a href="http://www.metabolichealthsummit.com">www.metabolichealthsummit.com</a> for more information about the upcoming Metabolic Health Summit conference.

Elizabeth Donley—NeuroPoint DX—Implementing Metabolomics for Earlier Detection of Autism Spectrum Disorders

Nov 5, 2018 26:44

Description:

Stemina Biomarker Discovery was founded about 11 years ago by Elizabeth Donley, who aimed to use the study of metabolism (metabolomics) to understand how the underlying biological and biochemical reactions differ between various disorders. Donley works primarily within the neurological disorders division for NeuroPoint DX and is focused on applying metabolomics for the detection of autism spectrum disorders. The most recent paper on the subject looked at amino acid dysregulation in autism spectrum disorders and showed a strong association between low levels of branched amino acids and concurrently high levels of three other amino acids. The association accurately identified 17 percent of kids with autism and suggests that the outcome for those affected by autism spectrum disorders could be improved with a high protein diet.


The metabolic markers are identified by subjecting a sample of blood to mass spectrometry, which will show whether or not a child is positive for any of the 13 metabotypes that have been identified to date and that describe 30 percent of kids who fall on the autism spectrum. As it currently stands, the average age at which a child will be diagnosed with an autism spectrum disorder is 24 months based on behavioral characteristics, but many children do not receive diagnoses until they are much older, which means that time that could otherwise be spent using valuable behavioral therapies is being lost; it is Donley’s goal to change this.


The team at NeuroPoint DX plans to launch its first panel before the end of the year and has already received lab certification to accept blood samples from children in 45 states. They’re currently raising money to support further testing and validate the second panel, looking for partners for distribution, and exploring options in foreign markets. 


Tune in for the full discussion and send your questions to info@neuripouintdx.com.

Brainwave Rebirth–Dr. James V. Hardt, President and Founder of Biocybernaut Institute – The Fascinating Process of Biofeedback and How We Can Literally Change Who We Are

Nov 5, 2018 36:03

Description:

Dr. James V. Hardt, president and founder of Biocybernaut Institute, Inc. (<a href="http://biocybernaut.com">biocybernaut.com</a>), shares his personal experiences with biofeedback and brainwave work in general, and the incredible documented results that biocybernaut training can deliver for improved health and wellness. Dr. Hardt is a celebrated research scientist with an established history of over 40 years in the study and research of biofeedback. Hardt has authored or co-authored countless scientific research papers on the subject and he currently has more than 30 patents for the core technology, headset, training methodology and brain-centered portion of various virtual reality applications. Much of his extensive research has been supported by private and federal grants as well as generous contributions from respected organizations such as the Fetzer Foundation, and others. Hardt is a valued guest and keynote speaker and he has presented presentations at many prestigious national as well as international events. His findings have been published in numerous scholarly journals such as Science, Psychophysiology, and the Journal of Experimental Psychology, just to name a few. Dr. Hardt received a Bachelor of Science degree in physics from Carnegie Institute of Technology, as well as a master’s degree, and Ph.D., in psychology from Carnegie-Mellon University.


Dr. Hardt states that a biocybernaut is to inner space what an astronaut is to outerspace. The name biocybernaut is derived from linguistic components: bio, cyber, and naut. Naut is a Greek suffix that is defined as someone who ‘goes on a voyage or adventure.’ Cyber, which is derived from the word ‘cypher’ is used to denote ‘calculations’ and is, today, commonly referred to in computer calculating technology. Biocybernauts go on an inner adventure into the depths of their awareness. He recounts an interesting story that details his first experience with this type of training, in a research study many years ago. He describes that he became so interested in the research study that he requested to have additional time in the chamber that the study participants utilized. While taking his own time in the chamber, after hours, he was subsequently forgotten about, and was kept in the chamber for several hours, and during this time he experienced profoundly moving states and alpha surges that supercharged him to research and study the field further, which led to his eventual founding of the Biocybernaut Institute.


As is similar to meditation, the biocybernaut training is an attempt to tune into the interior state of mind. Brainwaves rule our thoughts, feelings, and intentions. Dr. Hardt explains that when we change our brainwaves we can actually, fundamentally change who we are. He discusses some of his federally funded projects that delved into the study of biofeedback in regard to anxiety. As Hardt explains, anxiety is more prominent in women than men, and in both sexes, it increases with age in those who suffer from it. His findings showed that the biocybernaut training provided new benefits to those in the study at 6 months and also at 12 months. Dr. Hardt relates how the training expands awareness, so individuals see themselves more accurately and in greater depth. With traditional meditation, the process is effective at increasing alpha waves, but it can be quite slow, as it can take 21 to 40 years to be rated ‘advanced’ in Zen meditation. The benefit to biocybernaut training is that it uses technology to speed up the process, to detect and amplify alpha waves up to 100,000 times, so the signal is large enough to be worked with by computers. Feedback is given when the alpha waves increase, and the tones get louder, essentially producing a symphony of your own mind’s creation. Essentially, biocybernaut training allows the brain to know what it’s doing, while it is doing it, and as a result, the brain can improve in a myriad of ways. Dr. Hardt details how creativity, IQ, as well as emotional intelligence (EQ) can all be dramatically increased through the process and training. 


The meditation and brainwave expert discusses the importance of clearing emotional traumas and how they can be major impediments to brainwave improvement. And the biocybernaut training provides effective means to remove emotional trauma baggage that can limit an individual’s progress forward. He discusses the pillars of training and the means for achieving profound improvements in one’s life. 


Dr. Hardt has devoted his life to the study of the electrophysiological basis of advanced spiritual states. He has traveled the globe in pursuit of his research, and to India especially to study advanced Yogis, with his technology. From Zen masters to Christian prayer, Dr. Hardt has continued his relentless pursuit of advanced brainwave and meditation connections that allow people to become the best form of themselves that they can be, reducing limitations and addictions, experiencing more joy, less anxiety, improving health and awareness, and developing more meaningful relationships.

The Future of AI – Dan Faggella, Founder and CEO of TechEmergence – Discovering the Trends and Following Future Developments of the Furiously Expanding Artificial Intelligence Market

Nov 5, 2018 23:56

Description:

Dan Faggella, the founder and CEO of TechEmergence (techemergence.com), delivers an insightful overview of the power of AI and how companies can utilize it to move their business forward. TechEmergence is a sophisticated artificial intelligence market research and media platform. Its CEO and founder is passionate about AI and machine learning and believes that the most important ethical considerations of the next three decades will be the creation or expansion of sentience and intelligence in our technology. Dan Faggella is a writer and keynote speaker. He has written for multiple publications that focus on the nexus of business and technology such as the popular Bay Area-headquartered, TechCrunch; the Boston Business Journal; VentureBeat; VICE MotherBoard, the online magazine and video channel dedicated to technology, science, and humans; as well as many other respected sites and publications.


As Faggella states, TechEmergence is the platform that answers the question, “What do the new capabilities of AI mean for me?” And TechEmergence is the definitive platform that allows business leaders to better understand how AI is impacting their business and industry, and most importantly, what they should do about it. As they state, TechEmergence is the industry source for authoritative market research and competitive intelligence for the many and varied business applications of artificial intelligence. Their critical mission is to provide executives and decision-makers the knowledge that they will need to maintain competitive insight, to engage in informed AI technology procurement, as well as strategic planning that centers on AI. Faggella discusses their mission of leveraging AI for business and policy leaders, and how they deliver usable, critical information that provides valuable insight. 


Fagella discusses some of the inevitable future trends that are, in his words, “almost unstoppable.” He recounts how companies often know that AI is important and is something that they should incorporate if they haven’t already, but the basic tenets of what they need versus what they think they need are often quite divergent. As he states, many times whatever makes its way into tech media and creates a splash is precisely what business leaders naturally gravitate toward, though their true needs may lie elsewhere. He acknowledges that consumer interaction and chat is beneficial but that there could be other areas a business may want to engage beforehand in regard to AI. He explains how cost is a significant factor, for implementation of quality AI in a business framework requires technologists such as data scientists, time, testing, and tinkering, and therefore smaller companies might fare better to wait until their capital expenditures in the AI sector can be more robust.


Fagella discusses some of the major forces of AI, such as user interface and usability, and how the needed skill level has constantly changed over the years. He states that while the implications for AI are enormous, that we are still only in an infantile stage, early phase two as he describes it. And unfortunately, the user interface of much AI that is being driven to the market is designed for those with wizard skills, so it will take some time for it to be ironed out and simplified such that the basic user can implement all that AI can offer. Fagella underscores the strong correlation between market share and large amounts of data, and how venture capitalists are excited about controlling the voluminous data that is continually being generated in the marketplace and shows no sign of slowing down.


Cloudy With a Chance for Profits – Maximilian Freiermuth, CEO of Genesis Cloud – How Businesses are Utilizing Cloud Computing and Public Clouds to Trim Expenditures, Cut Costs, and Expand Growth

Nov 5, 2018 23:19

Description:

Maximilian Freiermuth, CEO of Genesis Cloud (<a href="http://genesiscloud.com">genesiscloud.com</a>) discusses the accelerating market of cloud computing, services, advantages, and the future of public clouds in the marketplace. Maximilian Freiermuth has a serious goal—to make Genesis Cloud the largest public cloud on the market. He discusses the birth of Genesis as it rose from the founders of Genesis Mining who provided the necessary resources to start and scale their revolution in cloud computing. Genesis Mining is a powerful leader in the bitcoin mining space. In bitcoin mining, ‘miners’ purchase computing chips that are designed specifically for the process and they use them to run the specially crafted software. The software essentially forces the system to engage in and complete complex and difficult calculations, and when the process goes as planned, these miners are rewarded with bitcoin for their efforts.


Freiermuth’s company, Genesis Cloud, is focused on achieving tremendous growth, and its roots are firmly planted in hardware accelerated computing, as well as cryptocurrency and blockchain services. As they state, they have a variety of the largest GPU data centers in the world and they are bringing them together with an advanced, modern infrastructure for applications in machine learning, and select hardware accelerated applications as well.


Freiermuth discusses cryptocurrency mining and the general assumptions people make, some of which are correct and some incorrect. He talks about the importance of keeping operating costs low in order to be profitable in the space. And he details the costs of building data centers that can achieve the results necessary for growth. Freiermuth provides an overview of their services regarding infrastructure, etc., from renting computers within their existing data centers to use and direct at one’s discretion, to rendering, such as with studio movies, etc. that require long renders to create visual scenes, which would be a more service-oriented task. And with the latter, the cost savings can be incredible as cloud-generated rendering of computer graphic scenes can sometimes be produced at a significantly lower cost than creating scenes in a real-life setting.


The cloud computing authority discusses some of the supercomputing conferences that they will be attending and their goals for future progress and advances. One clear benefit for smaller companies is that they can take advantage of the expanding AI opportunities in business by utilizing Genesis Cloud’s computing power. By partnering in this way with Genesis Cloud, smaller companies will not need to incur risky capital expenditures for purchasing massive computing equipment themselves.


Freiermuth hopes to find new ways to offer services and support to the many individuals and companies that can certainly benefit by utilizing public clouds. And the Genesis Cloud team feels that no idea is ever too big to be considered, and they continually push themselves to advance and grow, as leaders in the booming cloud industry.


Details of Data Delivery – John Prisco, President and CEO of Quantum Xchange – How Quantum Computers Have Changed the Game, Forcing a Data Security Revolution

Nov 5, 2018 21:11

Description:

John Prisco, president, and CEO of Quantum Xchange (<a href="http://quantumxc.com">quantumxc.com</a>), provides a very detailed overview and analysis of the ever-changing data security industry, and how quantum computers are forcing every business and government agency to rethink how they send and receive sensitive data.


Quantum Xchange provides impeccable defense to commercial enterprises and government agencies that seek to keep their high-value assets safe and secure currently, and on into the future. As quantum computers will significantly change how organizations secure their most sensitive data, Quantum Xchange will continue to be a sought-after partner for any entity that requires the most premium security.


John Prisco has over 30 years of solid experience in the areas of cybersecurity, telecommunications, and quantum physics. He has championed successful revenue growth and provided quality leadership and management to a multitude of companies such as Triumfant, GeoVantage, and Ridgeway Systems. Prisco is devoted to Quantum Xchange’s mission, and its valued customers, partners, investors, and the many quality employees who have helped make Quantum Xchange the gold standard in data security. 


Prisco discusses how his company is a respected provider of unbreakable quantum keys and secure communications, and how they are enabling organizations to send unbreakable data over any distance utilizing the laws of quantum physics. He elaborates on quantum key distribution, which is a secure communication process that implements a cryptographic protocol involving components of quantum mechanics. Via quantum key distribution, two parties can produce a shared random secret key known only to them, which can be used to encrypt and decrypt messages. As Prisco explains, the keys will change their state if an unauthorized party were to attempt to eavesdrop on them. Anything intercepted will be completely unusable by the breaching party and will not unencrypt any of the secure data whatsoever. The security expert gives a thorough analysis of the process that parties use to decide upon their encryption, as he details the transmission of photons, overall security, and the classification known as teleportation. 


Prisco discusses the future of computing and progress that has been made in a relatively short time, and what advances are on the horizon. Large prime numbers that form the structure and base of today’s public-private key encryption protocols, Secure Socket Layer (SSL) and Transport Layer Security (TLS) will be easily and quickly factored by quantum computers and will leave mission-critical data exposed, and very much at risk. 


Prisco states that with their system, even one photon that is tampered with will be evident to the end user. He explains quantum random number generators that work on photonic principles and provides an in-depth analysis of the wave nature of light that impacts the security of data in the process. Further, the data security executive discusses the future of data security and how his company, Quantum Xchange, will continue to address the shortcomings inherent with modern-day encryption.


The Ketogenic State Tyler Cartwright,Trainer, Coach & Founding Member of Ketogains, LLC – The Structure and Science of the Ketogenic Diet, From Calories to Ketosis

Oct 31, 2018 49:25

Description:

Tyler Cartwright, founding member of Ketogains, LLC (ketogains.com), shares his incredible journey back to good health and fitness, and the many ways that his keto-focused company can help people reach their fitness and health goals more efficiently. Cartwright is walking proof of the benefits that are available through the Ketogains’ methods for he began his path back to good health at 505 pounds. Together with the support of his wife who had reached 300 pounds herself, they have found success over the past decade, both having reduced their weight significantly through diet and exercise. Cartwright has successfully stayed within 10 pounds of his current weight of 205 pounds and his wife, now down to only 160 pounds, has maintained her new weight for several years thus far.  


Cartwright discusses the origins of the ketogenic diet. He and his Ketogains’ partners observed that while keto was not a new concept, as weightlifters and bodybuilders have long been using it to cut weight and meet goals, it was not, however, is properly introduced as a means to better health and fitness for the non-athlete. He delves into the various diets, from paleo to keto, vegan to vegetarian, and discusses their individual merits, frameworks, and strategies to success. Additionally, he discusses micronutrients, the advantages of taking in a sufficient amount of protein, and the benefits of chewing and digestion. And he explains how many have misinterpreted the ketogenic diet, making the assumption that keto means ‘eat as much as you want’ when it simply does not, for as he states, caloric intake still matters. 


As the Ketogains team acknowledges, ketosis is a healthy side effect of their general macro and micro recommendations, but it is not the goal. Ketogains is a unified community-driven exploration of the path to physical excellence through ketosis. The team at Ketogains states that a ketogenic diet can assist most anyone to achieve personal goals of better health; increased endurance, strength, or speed; an increase of muscle mass; or the goal of simply sculpting a leaner body. It is an evidence-based path towards one’s ideal body recomposition.


Simply explained, a ketogenic diet is one that causes ketone bodies to be produced by the liver, that then shifts the body’s metabolism away from glucose and on towards fat utilization. He stresses the importance of energy balance and calories, in coordination with a successful ketogenic diet. He discusses the challenges of rapid weight loss that sometimes perplex people after they feel like they have plateaued, but have often become, perhaps unknowingly, more sedentary. Cartwright explains the methods he and his team use to help those who find themselves gaining weight again, in spite of their efforts to do the right thing in regard to diet and exercise. He states that at this point they begin to look very carefully at exactly what someone is eating, down to the details such as how much is being consumed, their micronutrients, clinical diagnosis, as well as genetic or metabolic factors. Additionally, he discusses various products and supplements, insulin levels, and exogenous ketones. He also discusses ketone esters and their new popularity in the market. He cautions however that exogenous ketones are not a successful way to lose weight, but that successful weight loss is more often through hormonal balancing and caloric intake. 


Cartwright’s career focus, which he is passionate about, is in working with clients who seek to change their lifestyle, behavior, and the nagging mental impasses that stand in the way of their success. Cartwright has experience working in bootcamp environments and individually with those just starting their journey, as well as others who have had some success and want to go further, and also those who feel they need to change what they are doing altogether, to find a new approach. He is keenly interested in biochemistry and bioenergetic factors, as well as the psychology of change and non-surgical fat loss through various methods including the ketogenic diet. Cartwright is recognized as a Specialist in Fitness Nutrition (SFN), a Certified Fitness Trainer (CFT), and a Specialist in Bodybuilding (SB) by the International Sports Sciences Association (ISSA).

Data Revolution – Ravi Sahu, CEO and Founder of Strayos – Transforming the Mining and Civil Engineering Industries Through the Use of Drone Technology and Data Analytics

Oct 31, 2018 24:19

Description:

Ravi Sahu, CEO, and founder of Strayos (<a href="http://strayos.com">strayos.com</a>) delivers a detailed analysis of the data revolution in the mining and civil engineering industries that is helping companies to safeguard jobsites, and save money by increasing efficiency. Sahu is a seasoned technology management executive with more than a decade of hands-on experience helping technology business models to respond to changing markets and their growing, diverse customer needs. He is a global executive and management professional who has collaborated with teams and held various leadership roles with a myriad of businesses and has successfully executed sizable IT engagements for many of his prestigious Fortune 500 clients. Sahu specializes in business advisory services and methods, strategic management, sales, pre-sales, growth strategy, competitive enablement, operations, and value creation strategies that can deliver strategic business outcomes. Globally educated, Sahu holds multiple degrees (MBA, BE) in computer science.


Strayos is a 3D computer vision and machine learning platform for the mining industry that seeks to optimize drilling and blasting operations. By using drone technology, etc. Strayos can assist industry leaders with drilling and blasting decisions by collecting data for analyzation and processing. Strayos’s data analytics software is designed to maximize the operational excellence within the civil engineering and mining industries. As Sahu states, mining is a costly industry but through the use of data analytics provided by Strayos’s software, managers can significantly reduce costs. The Strayos platform makes it possible to collect and upload images from any drone, and to generate orthomosaics, 3D Models, point clouds and digital surface models (DSM) from collected aerial data. Sahu details the need for precise calculations, such as geotechnical attributes, when considering drilling sites, and how access to the data in advance can greatly improve effectiveness. He expounds upon the rate and frequency of drilling and mining and how that is directly impacted by a particular industry’s current needs for materials, etc. He describes the benefits for job site automation and data analytics that Strayos’s platform can provide for any company in the civil engineering and mining fields. 


The Strayos mission is to transform how the world is essentially discovered, designed, and digitized by aiding and empowering a job site's workforce to deliver added value through powerful data. Strayos has significantly impacted the design and execution of blasting operations by optimizing efficiency, ensuring accuracy, and safeguarding job sites with shot planning and blast analytics tools. And for civil engineering, the Strayos platform enables builders to build with more confidence, offering valuable analytical tools within their zero-distortion dashboard that can track job progress with complete accuracy and make precise adjustments, which can save a lot of time and decrease costs by improving efficiency. Strayos enables the actionable intelligence from drone data that can impact nearly every aspect of operations. 


The data expert discusses the cost-effectiveness of transportation services such as loading and hauling, from fuel costs to road grades and ramp designs, all which can have a significant impact on a company’s yearly bottom line. Sahu discusses the aspects of computer vision in regard to drilling and how drilling strategies can be adjusted based on deviations and new data as it comes in. Sahu states that the size of the data set will definitely impact the performance efficiency with regard to time. Ultimately, according to Sahu, his team’s mission is to find the areas in an industry where production is not optimized, or could use improvement, and implement their solutions to maximize and optimize every aspect of the process.

Walk This Way Dr. Charlton Woodly,Board-Certified Podiatrist and Founder of Woodly Foot & Ankle – New Procedures and Advanced Techniques to Treat Foot & Ankle Problems and Injuries

Oct 30, 2018 28:53

Description:

Dr. Charlton Woodly, founder of Woodly Foot & Ankle (<a href="http://woodlyfootankle.com">woodlyfootankle.com</a>), delivers an informative overview of the many problems, injuries, conditions, and treatments for feet and ankles. Dr. Woodly is a seasoned, board-certified podiatrist with over 14 years of experience in surgical treatment, a sought-after specialist in minimally invasive procedures and a HyProCure Master Surgeon. Dr. Woodly treats a vast array of foot and ankle conditions, including common injuries, sports injuries, neuropathy, plantar fasciitis, toenail fungus, and more. And he has additional specialization in HyProCure, which has been proven to have an impact on the condition of flat feet by increasing motion and distributing weight throughout the entire foot. Dr. Woodly is an expert in platelet-rich plasma therapy to combat heel and ankle pain, as well as with dermal fillers that can replace natural foot cushioning that has been worn and degraded over time. 


The foot and ankle expert discusses his early work in open surgical procedures that utilized large incisions, then screws and pins for holding bone in place. While the procedures worked effectively, Woodly was concerned that heal time was often long and that his patients experienced pain. He sought a better way and was motivated to begin bringing minimally invasive procedures to his patients, procedures that only required small incisions that could be performed during an office visit and were cost reducing as well. He discusses the techniques used for remodeling joints, anesthesia, and recovery times. With less cutting, less swelling, and less pain, the advantages are significant and patients are very pleased to have these more advanced surgical techniques as an option for them for a wide variety of foot and ankle problems and injuries. 


Woodly explains the advantages of HyProCure, which is a minimally invasive procedure. HyProCure can be placed in the naturally occurring space between bones to immediately realign and stabilize the hindfoot. The procedure utilizes a titanium stent that helps to prevent foot rolling and hyperpronation that causes pain. He explains that the HyProCure procedure offers a successful alternative for people that can offer long-term improvement. He details the importance of stretching and proper shoes to further increase mobility and decrease issues. 


Woodly provides insight into plantar fasciitis and the laser treatments that can provide relief by relaxing muscles in the back of the leg and decreasing inflammation. Additionally, the process reduces the need for cortisone injections, which as Woodly explains can be very painful for patients.


Woodly talks about his practice and how he tries to treat all patients the way he would want to be treated himself, thus he prides himself on thinking outside the box to provide techniques and procedures that allow his patients to have multiple options to solve their foot and ankle problems. 


Dr. Woodly has a medical degree from New York College of Podiatric Medicine and completed his internship and residency at Gouverneur Healthcare Services and the Jacobi Medical Center, both within the city of New York. He is currently on staff at Weatherford Regional Medical Center in addition to his extensive work at Woodly Foot & Ankle, and he is a member of both the Texas Podiatric Medical Association and the American Podiatric Medical Association

Mairav Cohen-Zion, PhD—Dayzz—A Digital, Personalized Sleep Training Program

Oct 30, 2018 29:57

Description:

Sleep: we all know we need it, but many of us don’t realize how badly. Missing just a night or two of quality sleep can increase our susceptibility to the common cold, and chronic sleep loss can lead to much more serious conditions. With 60-70% of the global population failing to get the right amount of sleep, sleep deprivation is now considered an epidemic—one that’s affecting people across the age spectrum. However, seeking the right type of treatment is expensive, time-consuming, and often hard to come by.


Dayzz is a mobile app that aims to tackle this problem head-on by providing individuals with personalized sleep training programs while collecting data that will ultimately contribute to a greater understanding of the myriad sleep disorders affecting people.


Mairav Cohen is a clinical psychologist and the chief science officer at Dayzz, and she joins the podcast today to discuss a variety of interesting issues on the topic of sleep, such as how to know what the “right” amount of sleep is for you, how exactly the Dayzz app gathers information from its users, whether or not there are health benefits to being a “night owl” versus a “lark,” the impact of cortisol and melatonin on sleep, and what’s in store for Dayzz. Press play for more. 

Michael Schmidt - Gold Medal Environmental - From Europe to North America: A Zero-Waste-To-Landfill Solution

Oct 30, 2018 37:22

Description:

If it doesn’t end up in a landfill, the trash you throw into the dumpster will end up in an incinerator and release a number of toxic chemicals when burned, reducing air quality and contributing to carbon emissions. Existing waste collection and recycling companies are doing their best to recycle as much as possible, but their technology is limited, and with the relatively new restrictions from China on recyclable materials, we’re dealing with a larger volume of waste than ever before. There’s simply not a market for so many common waste materials, such as straws, plastic film, and fabrics.     


Michael Schmidt is the executive vice president of strategic growth and development at Gold Medal Environmental, a company that’s providing a landfill-free solution for commercial, residential, and construction materials. How does it work? Gold Medal Environmental uses a system backed by technology that captures the chemicals released during the decomposition of waste. Once captured, they are converted to supplemental coal, an EPA-recognized source of fuel. This will reduce the consumption of fossil fuels and prevent significant quantities of toxins from entering the atmosphere.


It’s already been proven effective in Europe and is on its way to North America.

Abdul Basit Mohammad and Olav Mosvold—Avinor—Operating and Reducing Carbon Emissions in Over 45 Airports

Oct 30, 2018 27:48

Description:

On a global scale, aviation accounts for two percent of carbon emissions, which may not sound like a lot, but is equivalent to all of the carbon emissions produced by Germany each year. Avinor is a state-owned company and the main airport operator in Norway tasked with maintaining and ensuring adequate air travel services in over 45 airports and reducing carbon emissions from air travel. Abdul Basit Mohammad is the senior advisor at Avinor and is joined by project manager Olav Mosvold to discuss how exactly they’re doing this and the ways in which it could be improved.


Reducing energy consumption is the first step in reducing emissions, and this is done first and foremost by maintaining efficient traffic flow with minimal interruptions. Beyond efficiency, Mohammad and Mosvold discuss the viability of the electrification of aircraft and the use of biofuels as solutions to the problem of energy consumption and carbon emissions.    


American and European aircraft producers, as well as traditional jet engine producers, are conducting research and development projects focused on the economy of electrification, which has been promising: not only is the maintenance cost of electric motors lower than traditional jet turbines, but electricity itself is a lot cheaper than jet kerosene. 


Tune in and visit <a href="http://avinor.no">avinor.no</a> for the latest news and information on upcoming projects. 

Ozgur Tohumcu - Tantalum - Using Big Data for the Monetization of Vehicles and Connected Car Services

Oct 30, 2018 24:34

Description:

Since the first car sensor was created in 1968, vehicles have become exponentially more electronic and software-driven. In fact, some even have hundreds of sensors generating gigabits of data each day. In their vision of building a marketplace for connected car services and the monetization of cars, the team at Tantalum is taking advantage of all this data. For example, the ability to collect data about the way people drive (whether they’re speeding, obeying the traffic rules, etc.) will have a big impact on their risk profile, which in turn could lower their insurance premium rates.


Another use case is voice recognition for parking experiences, whereby saying the demand, “Park my car” uses location-based data and payment information already embedded in the app to create a seamless and simple experience all around. Other use cases include roadside assistance, improved fuel experiences, vehicle-to-vehicle communication, and an automated 911 feature. 


Tune in to hear Ozgur Tohumcu, the CEO of Tantalum, discuss all of these exciting use cases and more, and visit <a href="http://tantalumcorporation.com">tantalumcorporation.com</a>. 

Ravi Kurani - My Sutro-Affordable, Sustainable, Cloud-Based Water Monitoring System

Oct 30, 2018 19:44

Description:

Second, to the air conditioner, swimming pool pumps are the second largest consumer of electricity in the home and are overused when issues with water chemistry require pools to be emptied and refilled. In addition, dirtier water requires more energy, so money can actually be saved by keeping pool water clean and chemically balanced, to begin with. A pool owner must consistently and carefully measure five water parameters: nitrogen, phosphorous, potassium, pH, and alkalinity. However, it can be difficult and expensive to monitor and correct issues once they arise, leading to a lot of chemicals, water, and energy waste.


Now there’s an easier and more sustainable option offered by My Sutro: a small, floatable sensor that’s connected to the cloud on a 24/7 basis in order to monitor all five parameters, identify imbalances and send alerts when there’s something off with the water. If there’s a deficiency in one or more chemicals, My Sutro will deliver them to your doorstep. Ravi Kurani is the CEO of My Sutro and explains a variety of potential use cases for this product, including those that deal with drinking water, groundwater, and agriculture.


My Sutro has a handful of devices currently deployed across the U.S. for testing, and are planning a big launch just in time for the 2019 swimming season. Stay up to date on the latest and purchase your own sensor by visiting <a href="http://mysutro.com">mysutro.com</a>. 

Bridging the Human-Animal Gap and Lengthening the Bond—Dr. Barbara Royal, DVM—The Royal Treatment Veterinary Center

Oct 29, 2018 46:44

Description:

When an obese, arthritic, 12-year-old dog walked sluggishly through the doors of her hospital with a cancer diagnosis and a life expectancy of about four months, Dr. Barbara Royal wasn’t discouraged, or saddened, or intimidated by the work ahead of her; she was enlivened by an opportunity to grab from death’s door a life that had living left to do. The dog managed more than to merely hang on for four months; he lived vibrantly and energetically—running, playing, jumping…doing all the things dogs should do—for four more years. But this is really only half of the story. Similarly inhibited by their failing health and missing out on life while facing a murky future, this unexpected transformation encouraged his human companions to pause and ask, “Why not us too?” Within just a few months, the two had dropped over 100 pounds between them, hiked the Grand Canyon, and visited their grandchildren four states away—something which their health had never once allowed them to do. What’s the secret? It turns out there’s not much of one at all.


The impact of a species-appropriate diet and an integrative approach to medicine became powerfully evident to Dr. Royal not through years’ worth of education and the tens of thousands of dollars she spent on it, but by virtue of her own research and through her experience as a zoo veterinarian. The typical veterinary school curriculum in the U.S. includes only a minimal amount of education on nutrition and is taught by biased parties—representatives from major pet food companies—who stand to gain by pushing their product as the only proper diet for domestic animals. “The companies are trying to sell their food and judging things based on money, and I understand that, but my job is really different; my job is to judge things based on health,” says Dr. Royal. “Food really should mean something to us...we’re putting it in our bodies...people say, for $30 they can buy a bag of kibble and feed their Great Dane for a month...but what are they feeding them, and how can that possibly be good? If it’s that cheap, then someone’s cheating somewhere.”


Nutrition is the fulcrum of every choice Dr. Royal makes as a veterinarian, but she’s not blind to the fact that many people simply can’t afford everything she recommends. She reflects on that reality, stating, “Most of my patients say that I save them money in the end, because...every bit of the food is worth what they’re paying for; they’re not buying a bag of food where 50 percent…is sugar, or chemicals, or carcinogens…and that’s going to decrease the amount of medication and the number of times they’ll have to go to a veterinarian.” When it comes to nutrition, a little can go a long way, and she’s willing to work with every client who walks through the doors with their eyes open to the options that lie outside the confines of conventional Western veterinary medicine.


At first glance, it might seem counterintuitive that the booming, multi-billion-dollar pet industry would be churning out such high rates of illness and disease. When Dr. Royal graduated veterinary school, cancer was more or less a rarity, and now one in two dogs will receive the diagnosis. On top of that statistic, arthritis, obesity, allergies, and diabetes are at an all-time high. Why are our pets getting so sick? Driven largely by pet food corporations, the pharmaceutical industry, and expensive surgical procedures, this industry thrives off the structure of Western veterinary medicine—a structure designed to maximize productivity, leaving practitioners and technicians racing the clock and relying on generic treatments and medications in the absence of thorough, holistic, and individualized evaluations.


It’s a different story at The Royal Treatment Veterinary Center, where the literal structure reflects the interests of the animals; there are no exam tables, half doors divide sections of the hospital, and the walls are lined with the natural defenses of antimicrobial tree bark. At least 30 minutes are spent at the beginning of each consultation addressing every aspect of the animal’s diet, which equips Dr. Royal with the foundation she’ll need in moving forward with treatment, whether that means acupuncture, chiropractic, herbal, metabolic, laser, massage, or rehabilitative therapy. She pays keen attention to the behavioral characteristics and preferences of every animal, watching and speaking their language—a skill she honed out of pure necessity while working with wild animals in captivity. If a particular form of therapy is not well-suited for a particular patient, then she’ll reassess and try another. It is this method that has rendered Dr. Royal such an immensely successful veterinarian. “If I were a conventional practitioner and I didn’t have the tools I have...I would be feeding food that’s inappropriate for the species, and I would be seeing diseases chronically come back...and that would be very hard on my soul,” says Dr. Royal.


The interplay between the human-animal bond and the way we view the health of our animals versus the health of our own bodies will frame the core of Dr. Royal’s discussion at the 2019 Metabolic Health Summit: cancer. How can we help an animal use their own metabolism and ancestral cleanup tools to fight cancer, when should we avoid putting them through multiple surgeries, radiation, and chemotherapy, and in what way might these answers parallel those in human medicine?


Tune in to hear this enlightening discussion and visit <a href="http://www.royaltreatmentveterinarycenter.com">www.royaltreatmentveterinarycenter.com</a> to learn more about the services offered by Dr. Royal and her team. For resources in your area, visit the American Holistic Veterinary Medical Association website at www.ahvma.org and the International Veterinary Acupuncture Society website at www.ivas.org. For reading on the subject, check out Dr. Royal’s book, The Royal Treatment: A Natural Approach to Wildly Healthy Pets on Amazon. 

Dropping Weight – Dr. Tro Kalayjian, Board-Certified Internal Medicine Physician and Weight Loss Expert – A Diet and Exercise Program That Produces Real Weight Loss, Reverses Medical Problems, and Improves Overall Heath

Oct 26, 2018 48:15

Description:

Dr. Tro Kalayjian is a board-certified internal medicine physician and weight loss expert who has passionately devoted his life to bringing good health and wellness to everyone. Dr. Kalayjian delivers an interesting and useful overview of his methods to achieve weight loss and health improvement.


Dr. Kalayjian has a medical degree from Touro Medical College and he completed his internal medicine residency in the Yale New Haven Health System at Greenwich Hospital where he served as a chief medical resident. A prolific publisher, Dr. Kalayjian has released a wide variety of important case reports and findings in the areas of binge eating disorder, food addiction, and achalasia— a rare disorder that makes it very difficult for foods and liquids to pass into the stomach. His therapeutic focus includes obesity, hypertension, diabetes, hyperlipidemia, and metabolic syndrome. Dr. Kalayjian recommends a combination of intensive lifestyle changes including diet, exercise, stress management, and mental health care to many of his patients seeking improved health.


Dr. Kalayjian discusses the emotional and metabolic issues that could make weight loss more challenging for some. He recounts stories of patients who have run into difficulty losing weight even after undergoing dramatic procedures such as gastric bypass surgery, etc. As Kalayjian explains, there are many reasons why weight loss can be difficult and he works with patients that have diverse issues that present challenges for them.


Kalayjian provides a basic overview of his four-month program, starting with comprehensive lab work, an initial ninety-minute session and weekly follow-ups for up to eight weeks. Additionally, lab work is redone to assess changes, and subsequent consultations follow. Kalayjian monitors weight, body fat, blood pressure, body/fat/water mass, heart rate, glucose and more, to get a complete picture of a patient’s body and how it is functioning. He states his average weight loss for the program is about 35 pounds, with extremes of as little as four pounds lost, and 120 pounds as the maximum lost. Kalayjian discusses how his process first begins with figuring out what is causing the obesity in a patient, and only after reaching his conclusion can he then get them started on an appropriate diet, such as low fat, or low carb, ketogenic, etc., that will yield the results they are seeking. And while his patients are working toward their goal, Kalayjian also offers opportunities for them to socialize in various ways with others who are also seeking weight loss, to create a sense of community, one that provides support. He details the process as patients move into months three and four that may involve some fasting, dietary restrictions, time-restricted feeding, and exercise. Additionally, he talks about the problems people have when they plateau and some options, such as intermittent fasting and hunger assessments that may help them get past it and begin losing weight again.


The diet and nutrition expert details the important role that metabolism plays in weight loss. And he explains how some of the TV show weight loss programs that push fast weight loss have permanently damaged participants’ metabolism by approaching weight loss the wrong way. As he states, weight loss is a process and he advises one pound per week for most patients, to ensure a safe, effective, long-term strategy that can provide lasting results.


Kalayjian explains that the vast array of ‘eat more, move less,’ ‘count calorie,’ and other conventional programs and ideas really do not work for most people. Kalayjian’s goal is to provide a better way for his patients to find success in their weight loss plan, to lose the weight and keep it off for life. He recounts how his wife offered encouragement that nudged him to embark on his own personal weight loss journey, an experience that has helped him to better understand how to help others. He takes his patients’ journeys very personally and feels that if they fail, he has failed, so he makes it a point of never letting them fail, even if they have specific metabolic difficulties that may make their path to success a bit of a longer one. Kalayjian explains that diet and nutrition have been proven to not only impact weight loss, but also many other diseases and pre-disease conditions, and he is incredibly passionate about helping patients improve their health and be well.


Science Fiction Focus – Derek Künsken, Author of The Quantum Magician – The Technology and Science of Science Fiction Writing and What Happens When Science Fiction Becomes a Reality

Oct 26, 2018 22:48

Description:

Derek Künsken, the author of The Quantum Magician, delivers an interesting account of his background and path to science fiction writing. Künsken is a passionate writer of science fiction and fantasy predominantly, and his love of all interesting subjects, people, and places keeps him fueled and always pushing to create more. Since he was ten years old, Künsken has been singularly focused on his desire to write and create. Künsken talks about his journey from early childhood through his university work in molecular biology, to working with street kids in Central America, and how he finally came back to his first love—writing. He discusses his work, from short fiction to novels, and highlights the relevant physics that are featured heavily in his writing as he weaves tales about extreme situations in the universe and the existence of life in other environments. 


Künsken contrasts the novel world vs. the movie world and how film and TV don’t usually, because of the time limitations, delve deep into hard science. He describes that in the novel world, it is much easier to go into detail and explain the science that is involved in the subject matter, sometimes simply because there is just more of an opportunity in the written novel to elaborate and get into the fine details. And he delivers an interesting perspective on early science fiction film and television. In his discussion, he explains how Star Trek, the TV show, didn’t go deep into any actual science of the technological devices they used but rather took an interesting look at the impact of such scientific technology on those who were able to access it.


Künsken gives an overview of his method for creating The Quantum Magician, and discusses what intrigued him, and compelled him to write the novel. He explains that it was actually his own personal anxiety about the progress and direction of technology that was a motivating factor. He wanted to look at the uncomfortable questions that could come forth, such as what happens when people are given the opportunity to engineer their children before they are born, by changing their DNA, and how would a society function in space with no police presence, etc. From biological quantum computing to eleven-dimensional space and wormholes, to time travel and beyond, Künsken describes how he wanted to allow himself to push his most thought-provoking scientific and technological ideas. And he details his process for implementing the math, science, neurology, and technology into his work, describing his use of research coupled with his own personal knowledge from his university studies.


The science fiction author provides his personal thoughts on the genre in general and some of its common tropes and structures. He states that science fiction is particularly good at delivering cautionary tales. He talks about the unintended consequences of advanced science in a practical sense and how society may interpret the use of this science and technology as it advances, and the legal implications as well. 


As a guest speaker at many world conferences on scientific topics, Künsken states that he is constantly meeting interesting minds in the scientific world, and he explains that amazing new scientific ideas and theories are being pushed forward at an astounding pace by these inventors of the future. 


Fill’er up! – Adam Cooper, Co-founder of GasMob – The Power of Technology, Bringing Fuel to Vehicles with the Ease of an App!

Oct 26, 2018 17:33

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Adam Cooper, co-founder of GasMob (<a href="http://gasmob.co">gasmob.co</a>), provides an interesting overview of how technology is changing everything we do, even how we fill our gas tanks. To say Cooper is pumped about the future of GasMob’s fuel-filling technology would be an understatement as he is brimming with ideas about the many benefits his company’s app can offer to individuals and businesses everywhere. 


Co-founders Adam and Brad Cooper grew up in the thriving metropolis of NYC, specifically Manhattan, and through the years they observed that the increased need for residential properties in a city with a finite amount of land, surrounded by water, was creating a desperate situation for motorists who sought an easy fill-up. In fact, Adam Cooper states that there are as few as fifteen gas stations remaining to serve an estimated 1.4 million households that own a vehicle that requires gas. With massive real estate projects taking over most of the incredibly valuable lots once inhabited by petroleum resellers, the majority of gas locations exist, inconveniently for many, either on the northern tip or western edge of the island. Cooper discusses how he wanted to find a solution to the long lines, inconvenient locations, and the hassle, thus GasMob was born. With a background in finance and a strong passion for technology, Cooper reached out to his current partner, a respected oil and gas family, to launch the service.


Cooper talks about their platform and their initial foray into offering custom solutions as an amenity for residential and commercial properties, as opposed to a simply on-demand market model, though Cooper does expect to fully expand into on-demand further as well. Cooper provides details about how the service works for users, from initial sign up, to scheduling, and how property owners are pleased to have an additional amenity to attract residents. Cooper relates how it is as simple as opening your gas tank cover, locking your car, and letting GasMob handle the rest—filling your tank in the scheduled window you select and locking up your gas tank afterward, all while you enjoy your day or engage in work, never having to consider it or be hassled to do it yourself.


Cooper discusses the development of the app and how his team at GasMob is closely following every technology advance to continually update and improve their services. GasMob was brought to life by a team of talented developers led by a CTO who understands that technology and innovation go hand in hand. And as technology advances, their team continues to seek opportunities to partner and expand. 


The gas delivery guru discusses GasMob’s push to partner with entities that can help to capitalize their future endeavors as they continually innovate and target emerging markets. He talks about their work with companies who have fleets and some of the newer companies that could be in need. He describes their delivery trucks, the sizes and dimensions, and how their delivery vehicles are designed specifically for each unique purpose. Additionally, Cooper provides specific detail on the backend portal that fleet owners can view to dig deep into the individual analytics for their entire fleet. And as Cooper states, currently the company’s focus is to provide the absolute best service for fuel delivery, but he expects that the future will see GasMob expand into other auto-related services as well.

Translation Triage – John Fennelly, CEO of Lionbridge – How Technology and Advanced Translation Services are Impacting Global Commerce and Connections

Oct 26, 2018 18:05

Description:

John Fennelly, CEO of Lionbridge (<a href="http://lionbridge.com">lionbridge.com</a>), delivers an informative overview of the translation services industry, its global expansion, and how technology is changing the industry. Lionbridge Technologies, Inc. is a successful software and professional services company that specializes in language translation, e-learning translation, localization, software testing, internationalization, interpretation, software development, software testing, and content development services and strategies. Lionbridge’s CEO discusses the history of Lionbridge and their goal to provide a more personalized way to translate.


CEO John Fennelly is a seasoned leader and pioneering innovator in localization and translation services. His strong leadership has helped to produce significant organic growth at Lionbridge, now with over 6,000 employees on board ready to assist businesses, helping them connect with their customers anywhere in the world. Before Fennelly’s tenure at Lionbridge began he was the CEO of HireRight, a proven leader in the HCM technology space, where he led a major turnaround effort that culminated in record revenue and earnings growth leading to the profitable sale of the company. Fennelly has a long history in the information services and technology sector, working at notable companies such as Thomson Reuters, SunGard, and others.


The translation entrepreneur highlights the many ways Lionbridge can help companies succeed globally. He details the value of rolling out new products globally to customers in a manner which all documents, websites, user guides, and more are translated with accuracy for the intended readers, wherever they are, in whatever language that is needed. He discusses his broad team of close to 30,000 translation freelancers who work diligently to ensure quality is delivered for every client and their company or business, by understanding a company’s brand and unique messaging. And he details the importance of grasping various factors such as the differences between literal and nuanced translations that will resonate with the local market, driving interest and consumer connections. 


While English is widely used as a base language for many businesses, there is still high demand for direct translation into a large number of varied languages globally. Fennelly states that the history of translation services was largely based in the translation of technical documents, the ancillary parts of the system or product, but now with so many voice-activated devices coming to the market, the translation of those is changing Lionbridge’s space rather dramatically.


Fennelly provides his thoughts on the future of translation services, and how machine learning is an integral part of where the business model is going now that voice-activated services are able to interact with people in their native language. And Lionbridge plays a major role in helping companies train their machines.

Lionbridge believes that at its core, communication is always human, and the specialized Lionbridge community works tirelessly to add understanding to your data, and nuance to machine translation.


As companies continue to seek new opportunities, customers, and markets for their brand, Lionbridge seeks to move forward with them, assisting them with connections, delivery, and training for translation services at the highest level. Fennelly talks about the need for translation companies to transition from service-based to technology-based companies, and how some are falling short as technology expands at a blistering pace. As Fennelly states, companies that can successfully navigate that transition will be well positioned for success, and those that cannot will suffer.

John Limansky-Biohack MD-A Holistic, Tailored Approach for Preventing and Managing the Most Common Conditions and Diseases

Oct 25, 2018 40:49

Description:

As a traditional internal medicine physician, John Limansky began to notice that many of the most common and chronic diseases suffered by his patients were based around diet and lifestyle, and he soon acknowledged the importance of not just treating the symptoms of any particular illness, but understanding the underlying mechanism that contributes to so many of them. 


Dementia, cardiovascular disease, cancer, diabetes...the list goes on...but what do they all have in common? They’re driven at least in part by dysfunctional mitochondria, which is due to lifestyle factors, environmental toxins, and nutrition. With this understanding, Dr. Limansky began to realize the necessity of treating people one-on-one, which means starting with an extremely detailed questionnaire and assessment, gathering information on an individual’s genetic and metabolic profile, and then creating a tailored plan based on that patient’s current state of health and overall health goals. In order to share the knowledge and insights he’s gained over the years with people worldwide, he founded biohackmd.com, a website that allows anyone to access resources for learning biohacking techniques and implementing the optimal diet for leading longer and more healthful lives.  


Dr. Limansky touches on a range of insightful topics, including the problem with the standard treatment for prediabetes and diabetes, the effect of exercise and sleep patterns on insulin sensitivity, tools for achieving and maintaining health goals, and the surprising benefits of sitting in a sauna for just 20 minutes a day, four times a week. Hit play for the full conversation, visit biohackmd.com, visit him on social media, or reach out with questions at john@biohackmd.com. <a href="http://biohackmd.com"></a>

Gillian Szollos-Keto All Day Every Day-The Ketogenic Diet and a Life Transformed

Oct 25, 2018 37:20

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Gillian Szollos had always struggled with obesity, but it wasn’t until she began having seizures in 2014 that she realized something was really wrong, and that something needed to be done about it. The medications she was prescribed did nothing but worsen the seizures and produce unbearable side effects; she was at the end of her rope, and willing to try anything. That’s when her husband stumbled upon a seizure support group that introduced him and Gillian to the ketogenic diet. One of her doctors laughed it off as being effective only for children, while her other doctor had never heard of it; after just two weeks of adhering to a keto<a href="http://www.ketoalldayeveryday.com"></a> diet, Gillian was completely seizure-free and has remained so for four years now. 


Unlike the pharmaceuticals she’d been taking prior--which caused horrific side effects--the ketogenic diet came with a 90-pound weight loss, increased energy, and the resolution of her pain associated with fibromyalgia. To this day, Gillian remains an outspoken proponent of the ketogenic diet, aiming to share her story and what she’s learned through her website, Keto for Life, which can be found at www.ketoalldayeveryday.com. 


Gillian touches on the importance of remembering that we are individuals with different epigenetic and metabolic expressions, stressors, and lifestyles and that these factors impact how any one individual will respond to the keto diet--even she’ll admit that it’s not for everyone. 


Visit her website to learn more, and look for her at KetoCon this June in Austin, TX.

Brianna Stubbs, PhD-Research Lead Of HVMN & Co-Host of The HVMN Podcast- The World’s First Ketone Ester Sports Drink For Improved Performance and Cognition

Oct 25, 2018 31:24

Description:

There are a variety of exogenous ketone products on the market today, many of which are consumed by athletes and people looking for a natural source of energy to increase their endurance and physical performance. Most of these products, however, have to be consumed in relatively large volumes and have high quantities of artificial sweeteners. That’s not the case with HVMN Ketone--the world’s first ketone ester sports drink shown to increase endurance, athletic performance, and cognitive ability. 


Brianna Stubbs, Ph.D., is a research lead at HVMN Ketone and joins the podcast today to discuss the difference between the ketone salt products that have been on the market and the ketone ester used in the HVMN Ketone drink, and why ketone esters are far superior to ketone salts. By virtue of the fact that ketone esters are more potent than ketone salts, the drink can be consumed as a quick shot, rather than an unpalatable 16 ounces of liquid filled with artificial sweetener and a salty undertaste. 


Research on the benefits of ketone esters and the ketogenic diet, in general, has shown that beyond the ability to improve cognitive and physical performance, increased ketones in the body can boost brain metabolism and slow or prevent the progression of cognitive deficits such as Alzheimer’s.  


Interested in learning more or trying it for yourself? Tune in and visit hvmn.com.

Ross Taylor DropAnFBomb High-Quality, Keto-Friendly Grab and Go Snacks

Oct 25, 2018 23:04

Description:

For over 10 years, Ross Taylor tried to stick to a high-quality ketogenic diet while travelling the world for work; he quickly realized that accomplishing the two simultaneously was no easy task. “It’s easy when you’re not home to find proteins or vegetables...but getting enough fat--if you want to make fat your primary source of calories--is not always easy when you’re not home,” says Taylor. It was from this idea and this idea alone that Taylor and his wife decided to found a company--uniquely named DropAnFBomb--with the goal of producing natural, high-quality, low-carb, high-fat snacks well-suited for the individual who’s constantly on the move and determined to stick to a healthy ketogenic diet. 


DropAnFBomb sells nut butters and six different oils, each conveniently packaged in a pouch for easy portability. Free from fillers, artificial sweeteners, and really anything you can’t pronounce, these products just made sticking to the keto diet a whole lot easier. They started the company from the ground up, with no background experience in the food industry whatsoever. Taylor discusses the challenges they’ve faced, the successes they’ve had, what’s on the horizon, and how to try out these snacks for yourself. Tune in for all the details and check out <a href="http://www.dropanfbomb.com">www.dropanfbomb.com</a>.

The Cell Solution – Susan Stevenson, Executive Director, and Craig Mickanin, Director, Novartis – Gene Therapy Provides New Hope For Disease Treatment

Oct 23, 2018 24:30

Description:

Susan Stevenson, executive director, and Craig Mickanin, director, of the Swiss multinational pharmaceutical company, Novartis, based in Basel, Switzerland, deliver an informative overview of the incredible advances in gene therapy and transformative technologies that are rapidly changing the techniques medical professionals utilize to fight disease. Sue Stevenson is an experienced director with an extensive history in the pharmaceuticals industry. Her focus is in biologics, life sciences, validation, and cell biology. She holds a BS in chemistry from Western Maryland College as well as a Ph.D. in biochemistry and molecular biology from the distinguished Wake Forest University.


Craig Mickanin holds a BS in biology and history from the prestigious William & Mary University, the second oldest college in the nation, and a well-respected cutting-edge research university. The Novartis Institutes for BioMedical Research (NIBR) is the innovation engine and the NIBR team collaborates across various scientific and organizational boundaries, working for therapeutic breakthroughs for all patients.


Novartis’s stated mission is to utilize science-based innovation to address the world’s most challenging healthcare issues. Novartis seeks to discover and develop breakthrough treatments and successful ways to deliver them to the world’s population in need of care. Research and development (R&D) are at Novartis’s core and a key component to their primary strategy. Stevenson describes Novartis’s mission goal as it relates to disease treatment and prevention, specifically regarding cell and gene therapy. She discusses a few of their gene therapy methods, including the process of removing some of a patient’s cells, to modify those cells to, in essence, fight a particular tumor type, and then reintroducing the cells into the patient’s body so that the cells can get to work destroying the tumor. This cell therapy is an example of ex vivo therapy. Stevenson also outlines some of their early development on injectable options for cell delivery and the clinical studies that are going on currently.


The biochemistry Ph.D. details their exciting work that she hopes will bring truly amazing medical advancements to patients worldwide, such as restoring blindness, restoring hearing, and curing cancer, as well as some other in vivo studies that are showing promise.


Mickanin discusses his early work and provides some insight into how technology advances have helped buoy the transformative aspect of the field. He discusses current stem cell studies and the extent of their use in the industry. Mickanin details some of the aspects of the CRISPR technology, which stands for Clustered Regularly Interspaced Short Palindromic Repeats. Mickanin states that the system allows researchers to induce double stranded breaks into virtually any genome with specificity, and Novartis has been investing significant resources into the research. And Stevenson adds how their use of CRISPR/Cas9 technology will aid them in the process of introducing cells that can prevent disease or disease complications. She lays out the intricacies of the CRISPR/Cas9 and her hopes for its use ongoing, in future discovery and delivery of treatment options for patients.


Mickanin provides an overview of how ex vivo strategies and in vivo strategies are determined, and the issues that are involved when making a choice as to how to move forward with either for treatments. Stevenson discusses the expectations for the future and MIT studies that indicate perhaps as many as forty new gene therapy medicines may be released by the year 2022.

Total Health – Ben Bocchicchio, Doctor, Author, Health and Fitness Expert – High Intensity Exercise and Proper Diet For Maximizing Metabolism

Oct 22, 2018 40:11

Description:

Dr. Vincent “Ben” Bocchicchio, doctor, author, and health-oriented fitness expert delivers an interesting and important analysis of the body, exercise, and diet connection, and how we can all make positive changes that will improve our health significantly. Bocchicchio has over 40 years of experience in the fitness and health industry. He is a sought-after expert whose practical methods for achieving optimal health combine science with effective body conditioning and technology for top results in weight loss, and fitness. Dr. Bocchicchio was the pioneer developer of slow resistance training, a fitness technique that literally revolutionized the way people exercise.  


Bocchicchio’s book, Fifteen Minutes to Fitness: Dr. Ben’s Smart Plan for Diet and Total Health, outlines a sensible and rational approach to diet and exercise. Bocchicchio’s method produces significant results by working with physiology and it is a must-read for fitness and health professionals. Bocchicchio discusses his early years as a serious athlete and the fitness experts who influenced his journey. He talks about the history of health and fitness and the struggle to bring good fitness ideas into mainstream consciousness. 


The fitness guru discusses the development of his celebrated slow resistance training techniques known as ‘smart training.’ He describes his program as high intensity and it has garnered successful results for many of his clients and followers, from elite athletes to the average health-conscious person. As he details, his program requires just two 15-minute sessions per week to see a real impact on health and energy, as well as increase of metabolism. Bocchicchio provides insight on his thoughts behind the development of the smart training techniques. Bocchicchio states that he wanted to look at how our earlier ways of living impacted good health. He talks about how early humans did not have carbohydrates but had to exist on fish and fowl that required humans to hunt, which was an intensive workout. 


Bocchicchio provides some detailed information on insulin resistance and the negative impact of carbohydrates, and how our bodies truly don’t need them. He describes the process of fat cell storage, and how the prevalence of sugar in so many of our foods is leading to health problems. Essentially, Dr. Bocchicchio states that the consumption of carbohydrates is akin to ingesting insulin. And while a full diet and exercise plan is the best option, simply cutting carbohydrates is one step that everyone can take for their health. And Bocchicchio goes in-depth about the methods our bodies use to burn fat and sugar, and how fasting can provide an opportunity for the body to initiate an intensive energy burning process. When we eat, as Bocchicchio states, we are sending a metabolic signal to our bodies to store energy, and when we fast we are telling our bodies to burn energy. He outlines how intermittent fasting can be an option for people who want to stimulate their burn. 


Bocchicchio details the many types of exercise and workout plans that people invest their time into, and he stresses the importance of high-intensity exercise because it releases adrenaline, which in turn forces the body to release stored fat. He explains that steady state cardio exercise is good for overall health but that it will not change one’s metabolic status or make the body leaner. He states that in order to achieve the best results for metabolic purposes, essentially pushing the body to burn more energy, that we must work harder at a high-intensity level, which can only be done in short blocks of time due to the intensity it requires. 


The diet and fitness expert delivers an intensive overview of other factors that drive insulin resistance and the dangers of sugar loading. He talks about exercise techniques and gives specific examples of methods that everyone can use to improve their exercise regimens and general health. He discusses safe, productive, and intermittent exercising and the benefits of keeping a regular routine. Bocchicchio explains his personal workout routine and the advantages of working each set of muscles to failure, thus pushing the workout to a high-intensity level that maximizes the metabolic benefits. And he wraps up his thorough analysis of health and fitness by discussing some of his partnerships with various fitness groups and brands, as well as the tools one can use to exercise efficiently and intensely, for optimum health.

Why We Age – Siegfried Hekimi, Professor of Biology at Mcgill University, Head of The Hekimi Lab – The Complex Science of Aging, Free Radicals, Myths & Unknowns, and How Cellular Biology May Hold Answers to the Aging Process

Oct 22, 2018 41:45

Description:

Siegfried Hekimi is a professor of biology at McGill University and head of The Hekimi Lab where he and his team specialize in the study of aging. Hekimi delivers an informative overview of the complex, and often unknown, processes that produce aging, and the work his lab is involved with to try to uncover the mechanisms that accelerate, and retard aging, and why they do.


Hekimi studied biology at the University of Geneva. After Geneva, Hekimi began work at the celebrated Laboratory of Molecular Biology (LMB) of the Medical Research Council in Cambridge, UK, where he developed his method for using 'the worm' for translational studies on the biology of aging. While at Cambridge Hekimi identified the first mutants that supported the theory that aging could be manipulated genetically and that the process of inducing mild mitochondrial dysfunction can slow down the aging process of animals. Hekimi has worked and taught at McGill University for many years and is intensely focused on the important work his team is doing in the lab.


Hekimi discusses their laboratory work in genetics and the study of aging, as well as the process of drug development to combat aging. By using mutants of the microscopic worm Caenorhabditis elegans as well as the mouse to study aging, Hekimi hopes to develop new methods for medical intervention on the aging process. The Hekimi Lab focuses on gene activities that have a direct affect on mitochondrial function, and they are particularly interested in the biosynthesis and function of ubiquinone (UQ, Coenzyme Q, CoQ), the obligate, diffusible relay in the complete mitochondrial electron transport chain. The lab’s mission is to develop drugs that can alleviate diseases linked to ubiquinone deficiency. 


Hekimi discusses some of the surprising outcomes of his research, one major point being that free radical increase actually fights aging and prolongs life span, contrary to past scientific thought. He talks about his correlation between this study and research to mitochondrial damage, etc. He explains that free radicals are only potentially toxic because they are produced by various processes, and there are mechanisms within the cells that defend against this potential damage. As Hekimi explains, free radicals are in fact signaling messengers, which ultimately help cells stay in homeostasis by talking between compartments, etc. 


Hekimi states that the consumption of antioxidants has actually been shown to have no beneficial effects, contrary to widely accepted public opinion. He discusses his research with calorie restriction and metabolism, and the effects of mitochondria functioning at a slower rate. Some studies suggest that increased life span may actually be achieved by decreasing energy expenditure. By producing ATP (adenosine triphosphate), the primary energy carrier in all living organisms, more slowly, life span may possibly be increased. He talks about naked mole rats that live incredibly long lives, and yet their base level of free radical damage is exceedingly higher than mice or some other animals, which is further demonstrable evidence that the nature of free radicals is greatly misunderstood in the public consciousness. He explains that the same amount of damage happens in the mutant species but it happens over a greater span of time. Why this is happening in some and not others is one of the many questions that brilliant minds like Hekimi pose in their extensive laboratory research. 


The molecular biology expert explains the complexity of their research and how there are still very many unknowns in the general understanding of why aging occurs, why cellular damage happens and cannot be repaired, etc. He details some of their methods utilizing CRISPR and other work on drug development for mitochondrial diseases. Asking questions and searching for answers is precisely what Hekimi and his team focus on daily, and they hope to find causative links to explain why we age and how to slow the process in regard to disease and overall longevity. 

Mark Stephen Meadows-Botanic Technologies-Multimodal Bots and the Democratization of Artificial Intelligence

Oct 22, 2018 43:21

Description:

Mark Stephens Meadows developed his first simple chatbot in 2001, but what he’s working on now is much more than that: as the CEO of Botanic Technologies, he’s working on designing multimodal bots for conversational interfaces with several use cases, including gaming and healthcare. 


Designed as a combination of multiple AI systems, these bots have the ability to exhibit different facial expressions and use different tones of voice, thereby creating a more meaningful, human-like interaction for the user. Meadows explains what it is about bots that produce both trust and mistrust in humans, why people are likely to provide more information to and take advice from a bot than a human, and the single biggest design concern--how to avoid the uncanny valley effect. 


He also discusses what he believes to be the three primary ethical issues arising from the use of artificial intelligence, which formed the basis of Botanical Technologies’ venture called Seed. “...Because we have these ethical questions in front of us, we make a system that is completely transparent, completely open-source...and allows people to authenticate bots...Seed is a Marketplace for developers and the users of the bots to ultimately democratize artificial intelligence. We need to democratize artificial intelligence because we see a lot of things that could go wrong if we don’t,” says Meadows. So, what exactly could go wrong? Tune in for specific examples and an overall compelling conversation.

Thomas Seyfried, PhD-Boston College Biology Department-Metabolic Therapy A Toxic-Free and Potentially Standalone Treatment for Cancer

Oct 22, 2018 39:58

Description:

According to the American Cancer Society, over 1,600 people in the United States die from cancer every day, many of whom were receiving the current standard of care, which is radiation, chemotherapy, or a combination of both. Thomas Seyfried is a professor in the biology department at Boston College and strong proponent of using metabolic therapy as a form of treatment for every type of cancer, arguing that it’s more effective and less toxic than radiation and chemotherapy.  


So, what exactly does metabolic therapy entail? It’s based on a simple concept: growth requires fuel, so in order to stop the growth of cancer cells, their sources of fuel--namely glucose and glutamine--must be reduced or eliminated. Reducing the availability of glucose and glutamine results in an increase in ketones, which can be effectively used by the body’s normal cells but not by cancer cells. Seyfried explains how the primary difference between cancer cells and normal cells makes this an effective form of treatment for cancer, discusses how to achieve a state of therapeutic ketosis, and describes what to do once a state of therapeutic ketosis has been achieved. 


He also explains what’s standing in the way of widespread implementation of metabolic therapy in modern medicine, and the main problem with the gene theory of cancer and personalized targeted therapy for cancer. “The whole paradigm has to change, the whole concept of what people view cancer as has to change before we understand how much more effectively we can build therapies that don’t harm anybody,” says Seyfried. Tune in for the full conversation, and check out his book, Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer.

Travis Christofferson-Understanding and Treating Cancer Epigenetics, Metabolic Therapy, and Repurposed Drugs

Oct 22, 2018 35:02

Description:

What’s the ultimate cause of cancer? It’s not an easy question to answer, and according to Travis Christofferson, author of Tripping Over the Truth: The Return of the Metabolic Theory of Cancer, there’s no single cause, but a series of complex interactions and events that depend at least somewhat on our environment. Christofferson explains this in terms of epigenetic responses, which result in the turning off or on of certain genes--allowing some to be expressed and blocking others from being expressed. Diet, toxins, medications, and even loneliness are just a few of the factors that could trigger epigenetic responses and ultimately contribute to the determination of whether or not someone will develop cancer.


Christofferson offers an insightful conversation that touches on a range of topics, including the benefits of using metabolic therapy in conjunction with chemotherapy and radiation, the therapeutical differential between cancer cells and healthy cells that’s produced by the ketogenic diet, the use of aerobic glycolysis by cancer cells as opposed to oxidative pathways (the Warburg effect) and how this can be taken advantage of in the treatment of cancer, how and why the repurposing of drugs--in particular Metformin--holds promise as a form of cancer treatment, and why brain cancers seem to be most responsive to metabolic therapies. 


Click play to hear the full conversation, and check out his book to learn more. 

Digital Data Delivered – Toby Simpson, Co-founder and CTO, Fetch – How Artificial Intelligence Is Helping to Decentralize the Digital World for Useful Autonomous Economic Activity

Oct 17, 2018 24:46

Description:

Toby Simpson, co-founder, and CTO of Fetch (<a href="http://fetch.ai">fetch.ai</a>) delivers an informative, detailed overview of the future of data in the digital world, and how artificial intelligence is pushing innovation forward in a collaborative way. Simpson brings over 30 years experience in software development with ten as CTO across three companies to Fetch’s management team. He is a seasoned software developer and manager and has developed and built multiple highly successful computer games for various platforms. Simpson was an original developer at the established AI company, DeepMind, that was notably acquired by Google in 2014. And as the CTO of Ososim, he developed and designed a simulation engine capable of delivering collaborative learning experiences for the corporate market. At Fetch, Simpson utilizes his knowledge of software complexity and decentralized problem solving to design the next generation of advanced economic software agents as well as the environments in which they exist and prosper. Pairing digital intelligence with cryptoeconomics, Simpson seeks to build a more balanced and efficient future economy for everyone to contribute to.


Simpson discusses his passion for virtual environments, advanced machine learning, and AI, as he recounts memories from his early background that stimulated the birth of Fetch. He explains the concept of autonomous economic agents, which are adaptive, independent programs that can work for the individual, for an entity, or themselves for any reason they’re tasked. Fetch is a distributed network that is made up of nodes that essentially act as a service and directory for these autonomous economic agents. Fetch is the world’s first truly intelligent ledger as it allows data to act autonomously. Via machine learning and AI technology, the Fetch platform can enable data to work in a cooperative manner and thus solve problems immediately and deliver results to the user.


The data expert describes how Fetch is a decentralized digital world in which all useful and pertinent economic activity takes place. The digital entities (autonomous economic agents) can freely transact and coordinate tasks independently of human intervention and can thus represent themselves, individuals, or devices and services. He expounds upon the particular elements of the Fetch platform, such as the open economic framework. As Simpson explains, the digital world in which agents live is called the open economic framework. He describes this world as the ultimate value exchange dating agency of sorts in which each agent sees a space-optimized in real-time solely for them. And Simpson states that the open economic framework is their gateway to the digital world; it provides the senses for the agents, offering them the opportunity to see, explore, transact, and receive other information about what is going on in its digital world. Further, Simpson elaborates on the platform’s smart ledger, which is a next-generation type of learning ledger that can provide a collective intelligence to support agents’ individual intelligences, such as market intelligence, etc.


Simpson outlines some of the specific areas of industry in which the Fetch platform can offer incredible support and assistance, such as transportation, supply chain management, and hospitality. He discusses their corporate partnerships and the future expectations for Fetch. Simpson provides details on their successful private testnet that is currently working with over 100 nodes, that they are using to build real applications. And Simpson discusses their use cases and his future expectations for economic opportunities to exchange value. Additionally, Simpson enthusiastically details their market and how the Fetch platform can facilitate many individuals, entities, and businesses globally. 

Contract Review and Approval – Shmuli Goldberg, VP of Marketing at LawGeex – How Artificial Intelligence Is Improving and Automating Contract Review for Businesses Worldwide

Oct 16, 2018 28:56

Description:

Shmuli Goldberg, VP of marketing at LawGeex (<a href="http://lawgeex.com">lawgeex.com</a>), delivers a complete analysis of the inherent problems of the contract review and approval process that businesses contend with daily, and how artificial intelligence is making the work easier via automation. Goldberg has abundant experience in the areas of legal operations, analytics, and optimization with the special focus on helping legal teams reach their maximum potential. He served as senior technology evangelist at ClickTale, as well as director of marketing at Feedvisor. Goldberg is a regular guest and speaker at varied industry conferences across the globe.


Goldberg’s team at LawGeex works on advanced contract solutions for business. LawGeex offers award-winning software that automates the process of review and approval for everyday contracts. With a specialty in transformation of legal operations, LawGeex implements artificial intelligence solutions to aid legal teams with automation, thus facilitating in-house legal work, making it easier, more efficient and impactful—automation that enables their customers to focus on their overall mission and goals with less time needed for paperwork. Industry leaders acknowledge that inefficiency costs time, wastes money, and it lowers employee morale.


Goldberg discusses the many problems that are specific to contract review and approval, and how LawGeex employs the most advanced artificial intelligence, machine learning, natural language processing, and text analysis to assist with the review, comprehension, and ultimately approval or disapproval of a legal contract. He discusses the LawGeex platform and how it assists users to analyze their contracts’ contents and thoroughly compare to their legal team’s predefined criteria and input, or to their industry’s accepted benchmarks. By giving experienced lawyers the opportunity to focus on more complex work, and removing the grunt work from their day, attorneys can have more productive, satisfying days.


Goldberg states that it is inevitable that artificial intelligence will have a standing legal position going forward. He states that the use of technologies will become an accepted standard and future cases will set precedent as those who do not use basic available technology for important tasks such as diagnosis in the medical field, etc. could possibly be found to be negligent when problems arise. And Goldberg elaborates on how most bar requirements insist that attorneys utilize the latest technology in their legal work. 


Goldberg explains the specificity of their platform and how users can detail a long list of things they would like to see in a contract as well as things they do not want to see in a contract, and how the LawGeex AI-enabled software will deliver the results they seek. 


The legal AI expert discusses the future of contracts and legal claims. And he explains how AI and human work will coexist almost always, as deviations within software will typically require human interaction. As Goldberg explains most automated tasks go forward swimmingly, but in the event, there is a problem, humans decide the best course of action.


The Nutrition Advantage – Amy Berger, MS, CNS, NTP, Founder of Tuit Nutrition – Nutrition, Disease, Weight Loss & Cognition—We Are Certainly What We Eat

Oct 16, 2018 38:30

Description:

Amy Berger, MS, CNS, NTP, founder of Tuit Nutrition (<a href="http://tuitnutrition.com">tuitnutrition.com</a>), provides an extensive overview of nutrition as it relates to good health, disease, cognition, and well being. Berger talks about her family medical history and her concern that there was a lot of disease in that history. She discusses how she grew up as a chubby child and how weight loss solutions that actually work are so important. She recounts her own personal experiences with weight, knowing what it’s like to feel upset when you are counting calories, eating low fat, and exercising, but you still aren’t losing the weight, and your energy and mood is incredibly low. And while Berger learned through her own experimentation that reducing sugar and total carbohydrate intake was the key to successful weight loss, she states that through her extensive research she has found that weight loss is actually the least impressive task that carbohydrate reduction can accomplish.


Berger is a certified nutrition specialist and nutritional therapy practitioner who served her country in the United States Air Force. Berger’s expertise comes through years of research into low-carbohydrate nutrition, which can help people take back their vitality while eating delicious foods. As Berger states, staying well doesn’t require anyone to starve themselves, deprive themselves of tasty foods, or spend every day at the gym working out constantly. Berger’s business has a strong online presence where she provides a wealth of insightful, detailed information on a wide swath of health and nutrition-oriented topics, from metabolism and weight loss to insulin-related topics, thyroid function, and much more. Berger is the author of The Alzheimer’s Antidote: Using a Low-Carb, High-Fat Diet to Fight Alzheimer’s Disease, Memory Loss, and Cognitive Decline, a must-read for anyone who is concerned with improving health, vitality, and cognition, and finding ways to fight disease. She holds a master’s degree in human nutrition from the University of Bridgeport.


Berger discusses her extensive research into what she refers to as “nutritional intervention” that can potentially support brain health and assist those who have Alzheimer’s disease. She mentions that those who implement certain nutritional changes in their diet see noticeable improvement in cognition, behavior, and memory. She discusses the science behind the cellular conditions that arise which create a sort of “energy crisis in the brain.” She talks about how cells that aren’t getting energy from glucose anymore can still, remarkably, get energy from ketones. Ketones are a hybrid energy source and Berger states that they are the key to many issues. 


Berger gives an incredibly detailed overview of insulin issues and discusses how normal blood sugar can still contain extremely high levels of insulin, which can potentially cause gout, hypertension, and more. Thus, many people who aren’t actually diabetic can still have lots of chronic health issues due to high insulin levels.


Berger discusses hyperthyroidism and the issues that pertain to it, such as depression, inability to lose weight regardless of exercise and proper diet, hair loss, a feeling of being cold constantly, constipation and more. And she talks about the dietary myths that exist about various foods, especially proteins. And sadly, as Berger mentions, many doctors are simply not providing adequate testing to truly understand some patient’s issues related to the thyroid. 


The nutrition expert discusses ketosis in depth and how it works for the body. She expounds upon the topics of fat consumption, variability in individuals, and measures people can take to ensure they are getting the most from ketosis. She talks about how some people get hung up on the ratios in their diet, but that each person needs to look at their diet and consider the issues individually, as everybody is unique to some degree. 


As Berger’s voluminous research has shown, there are many myths that exist in regard to how the body processes food and what nutritional habits can or cannot do. And many times the key to understanding obesity, diabetes, heart disease, dementia, mood disorders, and other health issues lies in getting a deeper understanding of our bodies in relation to our diet.


Philipp Holl-Technical University of Munich-Wi-Fi Holography and AI-Based Fluid Dynamics

Oct 16, 2018 19:35

Description:

The hologram is a picture of the world as recorded by Wi-Fi,” says Philip Holl, explaining the bachelor’s thesis he completed at the Technical University of Munich. By recording all Wi-Fi signals that pass through a certain plane, Holl was able to create a 3D picture--or a hologram--of every object through which those signals passed. While it was done primarily for academic purposes, the use cases for this technology include indoor and outdoor tracking.  


As a Ph.D. student, Holl has shifted his focus into the world of artificial intelligence and machine learning and is currently working on using artificial intelligence to solve fluid optimization problems. For example, in order for a robot to pick up a glass of water without spilling it, the robot must understand how the water will behave within that glass. 


Holl also discusses a recent project in which he developed AI-based algorithms for determining whether rare events in physics can be classified as real, or are merely background events from other sources. Tune in for an in-depth explanation of all of Holl’s work, and feel free to reach out with questions. 

The Farm Fresh Factor – Kenneth Wu, CEO of Milk and Eggs – Farm Fresh Food Delivery to Your Door that Provides Better Food and Reduces Negative Environmental Impact

Oct 15, 2018 24:15

Description:

Kenneth Wu, CEO of Milk and Eggs (milkandeggs.com), a local farms food delivery business, provides a detailed overview of the current state of farm fresh foods, delivery, freshness, and environmental impact. As founder and chief executive officer of Milk and Eggs, Wu manages the company’s overall vision and planned growth strategies. As he explains, Milk and Eggs is an online farmers market with a delivery arm. Wu oversees the company’s investor relations as well as the general business development. Wu is a seasoned entrepreneur with over twenty years of business experience with a specialty in startups and new business ventures.


Wu was the founder of AirSplat, the largest retailer of shooting sports equipment, tactical accessories, and gear where he oversaw the company’s development, growth, and management. And Wu served as president of 2WheelBikes, a popular cycling equipment and accessories retailer. Other notable entrepreneurial successes in Wu’s long history of business expansion include his founding of Battle Arena, a virtual sports entertainment center and Cast Gear, a prominent tactical clothing and gear retailer.


Wu explains the process that makes Milk and Eggs work so successfully. He details how their produce and foods originate fresh from farms and foodmakers and are delivered to the consumer. He gives an overview of the methods they utilize to deliver the freshest goods in an efficient manner that is better for the environment as well. And as Wu explains, Milk and Eggs can keep prices low because there is no waste, inventory, middlemen, or large inefficient distribution centers and stores that require massive, costly real estate. He outlines the company’s focus on real foods, produce, etc. and discusses why they stay away from what he refers to as “center aisle” products such as chips, sodas, toilet paper, etc.


The farm fresh entrepreneur discusses their product lines and some of the specialty offerings they provide—curated boxes of items such as farm box, seasonal box, and office meeting box—each delivering different items for niche markets or desires. Additionally, he discusses their unique meal kits that are developed in coordination with local nutritional authorities, for those who really want to maximize their health benefits.


Wu details their focus on local artisanal products and the immense positive feedback they receive from consumers on these specialty products, from the access to foods that would normally require extensive travel, to the freshness of the ingredients and foods. He enthusiastically states that many of their customers truly praise the quality of their foods and have stated that the level of freshness is much higher than what they can find at their local grocery stores and markets. Wu describes the time frames that typical foods sit around before being purchased or consumed, and how Milk and Eggs has dramatically reduced the ‘sit time’ on foods, which is instantly obvious when consumers taste the freshness.


The food freshness expert talks about the problem of waste in the food industry and how it is a huge drain on our ecosystem. He talks about the percentage of food that is classified as ‘imperfect’ and what his company and others are doing to cut down on waste. Wu’s goal is to ensure that all food is used by donating to local food banks that support the community and those in need. And Milk and Eggs uses

minimal packaging and reusable insulated delivery bags to further cut waste, and any plastic bags they use are specially designed to be biodegradable to decrease pollution and cause no harm to wildlife.

Biology at the Brink – Pamela Silver, Principal Investigator, Silver Lab – The Bionic Leaf and Advanced Biological Experimentation That Could Help Solve Monumental Environmental and Sustainability Problems

Oct 15, 2018 28:55

Description:

Pamela Silver is the principal investigator of the Silver Lab (<a href="http://silver.med.harvard.edu">silver.med.harvard.edu</a>) and an Elliot T and Onie H Adams Professor of Biochemistry and Systems Biology at Harvard Medical School. Silver delivers an incredibly interesting and important overview of the biological advances that can help to reduce climate change and improve other pressing global issues through science.


Silver is a member of the Harvard Wyss Institute and the Harvard University Graduate Program in Systems Biology, as well as the Harvard Medical School BBS Graduate Program and the Harvard Biophysics and Chemical Biology Graduate Programs. Her passionate interest and curiosity with systems to synthetic biology drive her team’s research at Silver Lab. 


Silver’s team works in the arena of systems and synthetic biology to develop, design, and build biological systems in mammalian and prokaryotic cells. Working in a vast and diverse swath of methods and approaches from the computational to experimental, Silver states her team’s overarching mission is to address complex scientific questions that may impact the world and its population on a grand scale. Silver Lab works on many projects annually, from the reconstruction of entire new genomes to the hopeful development of principles for building synthetic cells that act as sensors, bio-computers, and memory devices, as well as the building of novel subsystems such as proteins with designed properties for general therapeutic use.  


Silver discusses her diverse work that tackles health-related issues, sustainability issues, climate change, and beyond, solutions to improve the way we live and interact with our world. She states her philosophy that biology is the best chemistry and talks about her work to replace many chemical industry processes with biological solutions in an effort to decrease stress on the environment overall. She details her “bionic leaf” project, which is a system that uses solar energy to essentially split water molecules and hydrogen-eating bacteria to generate and produce liquid fuels. The system can convert solar energy to biomass and the possibilities for this scientific advance are truly revolutionary. And she notes the particular importance of science-based solutions and the landmark Paris Accord (Paris Agreement), which is a multinational agreement on global warming and greenhouse-gas emissions, as climate change is truly accelerating. 


The biology innovator discusses the future probability of seeing more hydrogen-fueled automobiles and the current pushback against them, from the issues regarding the centralized production of traditional fuel sources, shipping concerns, and politics. And she explains how the push to move electric cars forward has perhaps stymied the hydrogen-fueled industry. 


Silver describes how some of the bacteria that exist within the bionic leaf can be engineered such that they can utilize all the tools for gene editing and gene engineering, and thus place genes into them that program the cells to make things, from molecules that look like biofuels, plastic precursors, and even feedstock for other elements.


Commanding the knowledge regarding how to program cells in a completely rational way can be extremely valuable for many advanced scientific areas from stem cell design, to drug therapy, and the environment. Silver’s lab strives to utilize a combination of theoretical and experimental approaches to further develop and improve what biology can offer us, in a myriad of ways.


Jussi Luntama-European Space Agency’s Lagrange Mission-Viewing Solar Activity From a New Perspective, Preparing for the Next Big Coronal Mass Ejection

Oct 15, 2018 36:48

Description:

It’s been about 150 years since the largest known coronal mass ejection (CME)--the ejection of millions of tons of plasma from the sun into space at a speed of 300 kilometers per second. On average, CMEs occur every 100 to 200 years, which means the next big event is inevitable. While it won’t threaten life on earth, it will put every satellite system at risk and threaten the safety of astronauts in space. 


As the head of space weather at the European Space Agency, Jussi Luntama discusses the 2018 Lagrange mission that aims to monitor solar activity and more accurately predict the presence and direction of a coming CME. The team working on the ESA Lagrange mission will park a spacecraft at Lagrange points, which are points where the gravitational pull of the sun and earth balance each other out. This will cause the spacecraft to trail the earth’s orbit at a distance of 150 million kilometers for eternity or until intentionally moved, and will allow them to view solar activity from a perspective that’s different from the one they have when looking at the sun from the earth. 


Tune in to hear Jussi Luntama discuss a variety of interesting topics, including the relationship between CMEs and periods of high and low solar activity, the effects of CMEs on power grids, and the launch of the Lagrange spacecraft planned to happen between 2023 and early 2025. To learn more, simply type “Where no mission has gone before” into a Google search engine. 

Ann Louise Gittleman-Author of the New Book Radical Metabolism A Powerful New Plan to Blast and Reignite Your Energy in Just 21 Days

Oct 15, 2018 24:51

Description:

Ann Louise Gittleman is an award-winning and New York Times best-selling author of over 30 books on a variety of topics, including weight loss, diet, and detoxification. Her most recent book, Radical Metabolism: A Powerful New Plan to Blast Fat and Reignite Your Energy in Just 21 Days, relies on the premise that the gallbladder is not a throw-away organ; it is an essential one that’s connected to the health of the thyroid gland and metabolism. 


Dizziness, radiating leg pain, and insomnia is just a few of the seemingly unrelated symptoms that can occur after gallbladder removal, but how do we compensate for this loss, and how can we prevent removal, to begin with? Gittleman offers answers to these questions and many more. Her theory that there is a critically important connection between the gallbladder, the thyroid and metabolism are backed by Harvard researchers who found that people who improved their gallbladder health saw a 53 percent increase in metabolism. An additional study out of Finland showed that people who have reduced bile flow are seven times more likely to suffer from hypothyroidism. 


Gittleman discusses a range of topics, including the right and wrong types of high-fat diets, why some people might want to stop drinking kombucha, green, and white tea, and the effect of electromagnetic radiation on cortisol levels--something she refers to as “electropollution.”


Tune in for a compelling and eye-opening discussion, and visit <a href="http://radicalmetabolism.com">radicalmetabolism.com</a> for more information and free downloads.

Ben Hindman-Splash-A Personalized Planning Tool For Your Next Business or Party Event

Oct 15, 2018 22:09

Description:

Whether you’re planning a business event, festival, or wedding party, Splash can help by providing sophisticated event marketing software that allows for more predictability, personalization, and greater returns on investment. As the CEO and founder of Splash, Ben Hindman has learned that the most important aspect of any event is not about getting more people in the room, but about getting the right people in the room. 


In order to ensure that, Splash offers invitation software, a beautifully designed landing page and registration experience, reminders and automated emails, promotions, check-in apps, and post-event follow-up apps. Hindman discusses a range of topics, including the importance of design in event planning and recommendations on how to start planning your next event. “I’m really passionate about the in-person experience, I think it creates more focus, people pick their heads up and really look and listen...it brings them into the now,” says Hindman. Tune in for the full conversation, and learn more at <a href="http://splashthat.com">splashthat.com</a>. 

Sara Bird-uBiome-Easy-To-Use Kits for Understanding Your Microbiome and Improving Your Health

Oct 15, 2018 23:12

Description:

Looking to deepen your understanding of the human microbiome or understand how it could be affecting your overall health? Dealing with a chronic gut issue such as IBD or ulcerative colitis? Trying to manage a gluten or lactose sensitivity? uBiome is a biotech company that was established in 2012 with the mission of advancing the science of the microbiome and making products that will allow individuals to understand how the microbiome contributes to their health and wellness, as well as a variety of illnesses and conditions.


Since 2012, uBiome has amassed the world’s largest data set on the human microbiome, having collected over 250,000 samples; that number only continues to grow. They currently offer three kits: Explorer, SmartGut, and SmartJane. Based on a user’s goals and conditions, they will order one or more kits, submit a sample of their microbiome from one or more sites on their body, and complete a detailed survey that addresses their fitness routine, diet, sleep patterns, stress patterns, and daily activity. The team at uBiome will use this information in conjunction with the sequencing data from their sample in order to provide an assessment of how their microbiome changes over time and contributes to their health. 


As the Vice President of Product Technology at uBiome, Sara Bird provides an informative and interesting discussion about the ins and outs of everything offered by uBiome, the ways in which the microbiome plays a role in myriad conditions, the increasing use of microbiome data by physicians, and how to get started with your own uBiome kit today. Visit ubiome.com to learn more about each product offered. 

Jarie Bolander, COO-Lab Sensor Solutions-Tracking and Maintaining the Integrity of Medical Samples in Transit

Oct 12, 2018 21:34

Description:

There are a wide variety of medical tests and samples that are time, temperature, and handling sensitive; if either one of these factors isn’t properly maintained, then inaccurate results will be delivered, putting the health and lives of patients at risk. With an error rate of 35-40 percent, blood samples taken for the purposes of monitoring chemotherapy are the most vulnerable to becoming compromised by environmental variants encountered before they even reach the machine for analysis, and a variety of other medical samples have an average error rate of between five and eight percent.


Lab Sensor Solutions is a company that’s developed a system to address this by closely tracking the temperature and location of sensitive medical samples with less than a five-minute delay. How do they do it? Since such sensitive samples should be kept in close proximity to the courier who’s transporting them, Lab Sensor Solutions places Bluetooth-enabled, low-energy temperature sensors inside the containers holding samples, and connects those sensors to the courier’s own mobile device. If a sample has been sitting too long, has reached too high or low of a temperature, or is on a route that will take longer than the sample will stay viable, then an alert will automatically be sent to the courier, the dispatcher, and the supervisor on shift. 


Prior to the implementation of this system, there was no way to identify when a sample was at risk of spoiling, but now the team at Lab Sensor Solutions is seeing on average three to five corrections a day and a significant increase in overall compliance. They already have 12 customers all around the country and are continuing to expand. Tune in and visit Lsstracks.com to learn more. 

Jonathan Smalley-Yaguara-A Fitness Tracker for Your Business

Oct 12, 2018 13:35

Description:

You might already be familiar with it--the quarterly or annual struggle to gather your company’s data and retroactively determine whether or not you’ve met your goals, only to forget which metrics you were really trying to improve or find yourself asking, “What went wrong, and how do we fix it?” But did you know that setting and tracking your company’s progress toward goals during the time period within which they should be met makes it 90% more likely for you to actually achieve those goals? Yaguara is a company in the business of helping companies do just that.


As the CEO and founder of Yaguara, Jonathan Smalley calls his company a “fitness tracker” for businesses, one that helps tie real-time data into the process of accomplishing company goals by measuring progress in real time and predicting based on historical performance and current progress how long it will take to accomplish those goals. The team at Yaguara also provides insight and recommendations based on the data collected, such as which media sites a company can reach the most customers, and what each individual within the company can do to to further the overall progress of the company.


There’s a lot on the horizon for Yaguara, including new content-based templates, new modules, improved algorithms for improved recommendations, and paid pilots in markets outside of e-commerce beginning in 2019. Tune in and visit yaguara.co for more!

The 3D Metal Movement – Jonah Myerberg, Co-founder and CTO of Desktop Metal – How 3D Metal Printing Is Improving Quality and Efficiency in the World of Manufacturing and Mechanical Engineering

Oct 11, 2018 27:25

Description:

Jonah Myerberg, co-founder and CTO of Desktop Metal (desktopmetal.com), discusses the current state of technology in 3D printing and how it is revolutionizing engineering and manufacturing. Myerberg oversees the technical direction of Desktop Metal’s 3D printing solutions. He founded Boston Impact, an engineering consulting firm, in 2013, and has worked at the top level of many successful businesses focused on high-performance battery development, including Renovo Auto and A123Systems. 


During his tenure with A123Systems, Myerberg helmed the motorsports business unit that focused primarily on the development of high-performance batteries that were later adopted by many leading Formula One teams such as McLaren, Force India, Mercedes Benz, and Red Bull. Additionally, he was a race engineer for Porsche on their 919 teams and also for Mahindra Racing on the Formula E team. Myerberg has a bachelor’s degree in mechanical engineering from Lehigh University, as well as a master’s degree in mechanical engineering and manufacturing from the prestigious Johns Hopkins University.


Myerberg states that his primary goal is to make metal 3D printing more accessible to manufacturers and engineers. Myerberg’s company, Desktop Metal, specializes in bringing new capabilities to the world’s first office-friendly, metal 3D printing solution. They provide high-resolution printing that can be in-house and built to exact specifications and scale. Desktop Metal’s Studio System abandons the traditional lasers and loose powders typically associated with metal 3D printing, which allows for higher safety standards. And businesses appreciate that power and an internet connection can get them going, simply and efficiently, without third-party equipment. 


Myerberg compares and contrasts plastics 3D printing and metal 3D printing and details the variables with both, outlining polymer printing techniques for plastics versus the solid-state techniques needed for metal printing. He explains how his company has taken advantage of polymer techniques to bring that technology to the office environment for metal 3D printing.


The 3D printing and engineering specialist expounds upon the technical manufacturing knowledge that is needed in the mechanical engineering world. He discusses the new tools that are being utilized specifically for 3D printing, such as Desktop Metal’s Live Parts, which is proprietary software they developed that allows engineers to input their specifications and constraints in order to allow the software to actually grow the part between the holding points, establishing the geometry via the software. This saves time and creates a very efficient process as engineers can spend more of their day on engineering tasks, and less time on solving parts problems. 


Myerberg lists some of the many advantages of 3D metal printing, such as reduction of total number of parts by streamlining the geometry, and significant decreases in the weight of parts overall by utilizing layer construction and other methods. And Myerberg provides his insight into the future of 3D metal printing. He gives examples of some of the companies they work with who are helping to drive the technology forward as they collaborate.

Nav Dhunay, President & CEO of Imaginea Ai – How Artificial Intelligence Is Helping Businesses to Automate Tasks and Utilize Data for Increased Efficiency and Productivity

Oct 11, 2018 19:52

Description:

Nav Dhunay, president and CEO of Imaginea Ai (imaginea.ai), presents a detailed overview of artificial intelligence technology that is bringing more efficiency and productivity to businesses globally. Dhunay brings a diverse background and experience to the position of president and CEO of Imaginea Ai. Dhunay has made significant achievements in the fields of artificial intelligence and clean technology and is a respected voice in multiple fields, including technology and energy. He is a sought-after expert in the area of early emerging trends in evolving technologies. Dhunay has strong ties to Silicon Valley and an intense drive to push for innovation within his companies by fostering an environment where experimentation and collaboration are encouraged. Dhunay’s prime areas of focus are in technology, corporate development, management, business operations, strategy, product development, startups, and company culture.


Dhunay’s company, Imaginea Ai, is an artificial intelligence company whose mission is to help industries work better, faster, more efficiently, and smarter. The Imaginea Ai platform was crafted with the idea that innovation arrives through the liaison of global talent, leading-edge products, and highly driven commercial organizations, and by allowing AI to be fully integrated. Dhunay states that AI is not accessible to everyone so his company wants to change that dynamic in terms of access to clean data and affordability, etc. He explains that by increasing the global pool of data scientists, costs can come down across the board.


Dhunay talks about Imaginea’s platform specifics, and how it provides an opportunity for organizations to engage in meaningful, technology-driven partnerships in order to tackle real-world problems. By linking with global AI technologies and specialist talent, and allowing buyers and sellers to transact with complete transparency and security, Dhunay’s team seeks to truly democratize AI.


Dhunay discusses the importance of tech talent and nurturing data scientists. He gives an overview of how 99-cent apps have truly changed the way some businesses work by simplifying tasks through the use of these apps. And he explains how cryptocurrency and blockchain has innovated the platform by simplifying transactions and processes. And Dhunay speaks about the possibility that Imaginea Ai may soon develop their own token or work with other top cryptocurrency that is currently in the marketplace, in order to further accelerate access to their platform.


The AI expert provides details on some of the areas that he and his team at Imaginea Ai are excited about, such as the marketplace that Dhunay refers to as a smart market, which is a place where data scientists can commoditize their artificial intelligence. Dhunay explains that he wants to give data scientists this opportunity to share the work they create, outside of their job, to provide them additional revenue, and to give the community more AI options to utilize for their work-related tasks and functions. Dhunay states that he hopes to give the community a one-stop-shop platform that benefits the creators, and the users, as artificial intelligence technology is applied on a mass scale to dramatically change industrial operations worldwide.

Emotional Rescue – Sarah Hill, Chief Storyteller and CEO of Healium – The Technology Innovations That Are Helping People Access Their Emotional Experience, and Affect Positive Changes

Oct 11, 2018 25:15

Description:

Sarah Hill, chief storyteller, and CEO of Healium (<a href="http://tryhealium.com">tryhealium.com</a>) provides a thoughtful overview of her exciting industry that is helping people to get in touch with their feelings and emotions and influence them in a positive way through the use of technology. Hill is the CEO of StoryUP XR, the visionary company behind Healium. She is a former television journalist for the NBC, ABC, & CBS affiliates in Missouri and a savvy media technologist with over 25 years experience building successful platforms. Hill has a strong journalistic background and many years experience as an interactive reporter often focused on the world’s negativity and trauma, and as such she is a national Edward R. Murrow, NAB Service to America, and twelve-time mid-America Emmy award-winning storyteller. She began working directly with augmented reality filters during her live TV newscasts in 2011 focusing on a variety of XR inputs such as heart rate variability and respiration trackers. 


Hill’s journalistic passion has taken her all over the world as she has delivered powerful stories of the human spirit originating in the Amazon, Congo, Zambia, UAE, Guatemala, and China. She holds a bachelor of journalism from the University of Missouri, Columbia. Hill’s company, Healium, is the first augmented and virtual reality (AR & VR) channel that is powered by biometrics. Hill details the Healium headband and how it measures gamma asymmetry that is associated with our feelings, such as love, joy, appreciation, openness, etc. Healium’s platform allows users to engage and take a more active role in their personal well being, to become more self-aware of the power of their feelings. 


The Healium experience is delivered through wearables including a low profile brain-computer interface (BCI). As stress is now considered to be an actual epidemic, Hill expresses the urgency to develop methods to alleviate stress and connect with our emotional state. Hill states that their platform helps users achieve a heightened sense of self-awareness, via biometrics, as the data helps to make users aware of the power of their emotions. She discusses neuromeditation and Dr. Jeff Tarrant’s fascinating work as his team uses state-of-the-art biofeedback technologies to monitor the brain and body in order to train the nervous system to return to a more optimal state. 


Hill discusses some of the published studies that concluded Healium’s platform demonstrated a reduction in anxiety for various users. She recounts stories of individual users who have shared their experiences learning about and trying Healium for the first time. And she details some of their comments regarding the experience, their recalled memories, feelings of altered states or relaxation and others while using the platform.


The Healium low-profile headband known as a brain-computer interface senses electrical activity in the brain and a virtual reality headset then immerses the user into the experience. Additionally, the Healium augmented reality experiences are designed to work without goggles as well, with a simple smartphone. Hill shares her thoughts on the overall experience that users receive and how her team is extremely concerned that every user’s experience is a positive one.

Advancing Aesthetics – Alysa Hoffmeister, Senior Product Marketing Manager at Cutera – The Technological Advances Within the Aesthetic Industry That Are Providing Patients With Greater Options In Treatment and Care

Oct 11, 2018 17:04

Description:

Alysa Hoffmeister, senior product marketing manager at Cutera (cutera.com), discusses the expanding, changing, and exciting face and body aesthetic industry and how her company, Cutera, is solving problems and providing industry professionals with the tools to satisfy their patients’ needs. Hoffmeister explains the work they do at Cutera, developing advanced laser light and energy-based aesthetic systems for practitioners worldwide.


Hoffmeister is a seasoned medical device professional with a strong background in the industry. She is a results-oriented leader with extensive experience in sales, sales management and training, product/marketing management, and customer retention, as well as new business development. She is a powerful strategic sales professional who excels in advanced marketing for robust revenue growth. Her incredible experience includes tenure at Syneron Candela as their senior territory manager where she focused heavily on dermatology/plastic surgery and CO2RE Intima for OB/GYN. Additionally, Hoffmeister was VP of sales & marketing and general manager NA for DIP-Tech, territory sales manager and senior director of marketing at Alma Lasers, and the women’s health care and general imaging ultrasound senior account manager for Philips.


The aesthetic technology-marketing expert explains some of the technology behind their products, such as the effects of laser contact with the skin, blasting melanin, etc. She discusses the technical aspects such as wavelength and depth that pertain to laser work for tattoos, freckles, and other skin issues that concern patients.


Cutera develops devices that give medical aesthetic professionals the ability to evolve in the expanding and competitive face and body aesthetic industry. Cutera’s one-of-a-kind devices offer professionals the opportunity to innovate and provide new and exciting options for their patients, solutions that get results. As Hoffmeister explains, Cutera partners with physicians to fully understand their needs, in order to properly deliver ideal solutions that exceed their expectations and ultimately provide superior patient satisfaction. Cutera’s products are engineered at the highest level for maximum performance, safety, and efficacy.


Hoffmeister provides information and details about Cutera’s other products, such as their non-invasive radiofrequency devices that are utilized for fat destruction. But as Hoffmeister explains, their process is slow (about 12 weeks) and effective, a more measured response that targets the fat cells with heat, over time, so they can be eliminated through the body. She discusses their many products and how solutions need to be unique, tailored specifically to individual patient’s needs, and how Cutera’s goal is to make that possible. She details how Cutera’s solutions can target trouble areas for patients, reducing pockets of fat wherever they occur.


And Hoffmeister expounds upon the many areas that are popular and growing in the aesthetic care industry, but as she mentions, non-invasive fat reduction is by far the number one procedure in demand in the industry overall. She discusses the Cutera expansion and how demand for their products is booming, but Cutera is not a company that rests on its laurels and as such their research team is continually working to develop new, innovative products for the future, to help improve patients’ lives.

Managing Mental Healthcare – Ravi Sharma, the Co-founder and CEO of OOTify – Improving Opportunities For Those Who Seek Quality Mental Healthcare, Via Technology

Oct 11, 2018 27:16

Description:

Ravi Sharma, the co-founder, and CEO of OOTify (<a href="http://ootify.com">ootify.com</a>) delivers an informative overview of the important work his company is engaged in that seeks to bring quality mental health care to everyone who needs it. Sharma has a wealth of experience in multiple sectors of industry and is a proven leader in business, technology, and investing, but his passion and primary goal is to improve mental health options for everyone. Sharma’s background includes his tenure at Western Asset Management Company where his skills in on-boarding quality lenders, drafting underwriting guidelines for investment mandates, loan level due diligence for credit and compliance, and more, helped lift the company to a higher level of success. And in just 3 years at Western Asset Management Company, Sharma grew the loan portfolio to more than $1 billion, targeting double-digit returns. Before his successful time with Western Asset Management Company, Sharma helped to build and then exit several tech companies. He is a strong advocate for mental health and clean technology.


Sharma describes OOTify as a mental health marketplace that seeks to match individuals with the best possible providers for their unique needs. OOTify is a community of professionals, mentors and peers focused intently on personal development and helping individuals build healthier relationships. Part of the company name, ‘oot,’ is derived from the Hindi language; it means, simply, to ‘lift up,’ and OOTify’s mission is certainly all about lifting people up. OOTify allows users to connect with mental health professionals, a life coach, or verified mentor, easily and swiftly, via their phone. Sharma describes the many options users can take advantage of on the platform, such as audio, video, or messaging, connecting with trained professionals who can help, right from the comfort of the user’s phone. It’s on-demand online therapy that seeks to improve lives. Sharma discusses ‘the fabric,’ which is his term for the community forum that is a compilation of different threads that is modified by multiple, qualified individuals who provide support. Users can benefit from hearing and reading about others’ experiences, engage in Q&A with experienced professionals, and more.


Sharma describes how OOTify’s powerful mental health technology utilizes artificial intelligence (AI) to match mental health providers, life coaches, and other carefully screened professionals to users through their open marketplace. OOTify will assist with the intake process via their AI chatbot, streamline it, and improve the process of delivery of quality mental health care. And Sharma discusses the importance of quality matching, which is why OOTify’s intake process is essential. For as Sharma states, while the most educated and celebrated authority on a particular mental illness may seem perfect on paper, credentials, and experience aside, that individual may not be right for everyone because it is critical that the mental healthcare seeker connect or vibe well with their mental health care provider.


The healthcare technology advocate discusses the massive amount of feedback he has received from healthcare professionals who appreciate how OOTify is leveraging technology to bring care to individuals. Healthcare professionals acknowledge the power of the OOTify application as it hosts powerful productivity tools such as HIPAA compliant video, audio and messaging, and also assists with billing and scheduling. OOTify stresses however that the AI does not make any care decisions for those seeking help, but rather is leveraged to help providers match with new clients, gain insight via client data metrics, and generally be more efficient overall, so they can spend their time helping people as opposed to doing administrative work. 


Sharma details the OOTify rewards program and other ways in which they seek to acknowledge and support those providers who receive exceptional feedback and high ratings from users. He provides information on some notable acknowledgments of their groundbreaking mental health technology work that they have received from respected institutions such as the USC Keck School of Medicine.


OOTify partners with prestigious institutions such as the University of Southern California, Loyola Marymount University, and others, as well as many respected businesses and community leaders. And the community is supported by technologists, businesses, many other academic institutions, non-profits, teachers, parents, and nearly everyone who grasps the importance of providing quality mental health care.

The Future of Now – Jolene Creighton, Founder and Editor-in-Chief at Futurism, LLC – Technologies That Are Impacting Our Lives Today and the Future Tech That Is On the Horizon

Oct 9, 2018 31:34

Description:

Jolene Creighton, founder, and editor-in-chief at Futurism, LLC (<a href="http://futurism.com">futurism.com</a>), provides expert insight into the state of our advancing technologies and what the future holds for society. Some of Creighton’s past accomplishments include her tenure as co-founder of From Quarks to Quasars and her noted work as a freelance writer with Hattiesburg American. She was an instructor at the University of Southern Mississippi. Creighton’s Ph.D. work was focused on digital media & discourse analysis at the University of Southern Mississippi and her master of art study was at SUNY Brockport where she studied English language and literature/letters working toward her thesis on digital communication and viral storytelling. Creighton received her BA from Keuka College in Keuka Park, NY. 


Creighton is a noted public speaker and writer in the field of science via digital, print, and video output. She has taught more than two dozen university courses on writing and communication. Creighton’s work as editor-in-chief at Futurism brings together her many varied interests and profiles her expertise on the topic of future science and its applications across various media.


Creighton discusses the pace of change as technology is accelerating, and the additional power that is packed into our devices as they decrease in size but expand in capability. She touts the many benefits of the changing technology landscape such as the nearly instantaneous reporting of news and events through media platforms such as YouTube and others that have revolutionized the news dissemination avenues. 


Futurism is a media publication that covers the science and technology that is currently shaping our future. Creighton discusses their overall intention for the platform. Futurism’s mission is to deliver captivating news and further the dialogue about forward-thinking products and narratives that make an impact on our world. Futurism, as Creighton explains, seeks to bring thought-provoking news items that bridge the expanding areas of science and technology. She details the interesting case studies and questions that surround the safety, science, and responsibility of autonomous vehicles as they dramatically expand into development and use in our society. She discusses the vigorous scientific debate that revolves around vaccinations, and other significant areas of science and medicine, and more, and how fear of technology can sometimes keep people from accepting proven science that can improve their lives or help to keep them safe.


The futurist technology advocate also discusses some of the more dubious applications of technology such as social credit systems that rate the quality of someone as a citizen. She details how China is using algorithms to judge individuals and how parenting could be one way to increase someone’s score, as bizarre as that idea may seem. She provides information on the government policy and research that goes into the development of technology and the checks and balances that are in place to ensure that technologies benefit people in a safe and effective manner.


As technologies can be utilized for good and bad purposes and are being generated at a blistering pace, it is important to ensure that the development and release of technologies are monitored by multiple entities for the good of society. However, Creighton stresses that the overpublicized ‘worst case scenarios’ that technology detractors speak and write about are typically absurd and unrealistic, and have little to no chance of becoming reality. In essence, she states that most advancing technologies will be used to benefit our lives in multiple ways. 

Andrew Smith Lewis, Co-founder and CEO of Cerego - Improving Learning Through Artificial Intelligence, Predictive Learning, and Cognitive Science

Oct 9, 2018 30:58

Description:

Andrew Smith Lewis, co-founder and CEO of Cerego (cerego.com), delivers an informative overview of the ways we learn and how technology and AI is improving learning and increasing retention. Lewis’s passion for research was spawned at the Bronx High School of Science, and it was his insatiable curiosity for learning that carried him on to become one of the founders of Cerego’s learning method. Lewis and his team launched Cerego to create an open platform that could improve memory and quantify knowledge. His obsession with advanced learning was the motivation behind his successful launch of three education and technology companies, including the notable Princeton Review of Japan. 


As Lewis states, their mission is to make people smarter and improve learning through the use of AI and cognitive science. Lewis’s company, Cerego, is an advanced platform that can successfully drive a business or collaborative team’s training, learning, and skill set acquisition opportunities. Simple to use, yet multidimensional within, Cerego’s platform reinvents the basic elements of learning software by focusing on precisely how people learn as opposed to what they learn, for a more immersive learning experience that gets results. Cerego is revolutionizing the learning and training process for many companies and universities, and others are coming forward steadily to adapt Cerego’s successful platform for their teams. Lewis explains the importance of meta-cognition and the concept that very smart people may not necessarily be efficient learners, and Lewis intends to improve learning for everyone with his technology.


The platform’s algorithms deliver a schedule that efficiently guides learning for each individual, to help them achieve the maximum success in a manner that works for them by integrating detailed learning data, detailed scientific models of memory decay, and of course—the individual’s own personal learning history. Cerego users have achieved stellar results, as Cerego utilizes evidence-supported cognitive science algorithms working at the root of the platform to deliver instructional and quiz content to users at the right time, before the information is forgotten, which supports their learning and increases retention.


Lewis discusses the error corrective model, which is essential the platform’s ability to learn and improve how it delivers its information pursuant to each individual’s unique process. And he expounds upon some of the specific advantages, such as success rates for users and how in addition to the elevated number of users who now pass their tests more easily and quickly, their retention of the learned information is greatly increased as well. Additionally, instructors are reducing training time and repurposing that time on more one-on-one personal student interactions.


Lewis discusses the company’s focus on K-12 education, higher education, corporate, and government applications. Lewis explains how higher learning through technology teaching methods helps to create better, more satisfied employees and more successful, empowered students. Additionally, employers can access the learning data on individual employees, which can help employers place their employees into specific job functions, tasks, and areas in which they are best suited and will excel. 

Joshua Wiesman-SmiloBaby-Taking a Scientific Approach to the Development of Essential Products for Every Stage of Childhood

Oct 9, 2018 16:53

Description:

Until now, the products marketed for various stages of childhood have been designed in a generic, one-size-fits-all way that ignores critical stages of growth and development. But things are done differently at SmiloBaby, a direct consumer baby and child brand that’s backing the design of its products with science in order to create the safest, most innovative, and most effective products. 


As the CEO and co-founder of SmiloBaby, Joshua Weisman explains their two core products, the first of which is a palette support pacifier. Using finite element analysis to study how generic pacifiers deform in the mouth during use and lead to malocclusions and crossbites, the team at SmiloBaby has created a pacifier that supports the palette during the first 16 weeks of life when it grows by 30 percent. The second core product is a feeding bottle with a patented valve and nipple shape that’s been designed based on finite element analysis and a study of fluid dynamics. The result? A bottle that reduces air intake, thereby preventing common problems that result from generic bottles, such as ear infections, colic, and gas ingestion. 


With a team comprised of pediatricians, pediatric dentists, and lactation consultants, parents can feel confident that they’re giving their child the best when they buy from SmiloBaby. Tune in to learn about their other products, and visit smilobaby.com to make some purchases of your own.  

Jimmy Moore- Author of Keto Clarity and the Livin’ La Vida Low-Carb Podcast- How to Revolutionize Your Life on the Ketogenic Diet

Oct 9, 2018 53:32

Description:

In 2003, Jimmy Moore weighed 410 pounds and was dependent upon multiple prescription medications for high cholesterol, high blood pressure, and respiratory issues; he was just 31 years old. Fast forward to today, and he’s living his best and most healthy life, and as the author of Keto Clarity: Your Definitive Guide to the Benefits of a Low-Carb, High-Fat Diet and the creator of the popular podcast Livin’ La Vida Low-Carb, he’s doing everything he can to help others through their own health struggles. 


He joins the podcast today to focus on the common struggles faced by most who transition to the keto diet, including the “keto-flu” which can cause fatigue, an insatiable appetite, headaches, and muscle cramps. “If you’re getting any of those symptoms, that is a telltale sign that you need four things in abundance,” says Moore. What are they? Tune in for the answer and an explanation as to why they’ll get you through the toughest part of transitioning to the keto diet, as well as Moore’s invaluable tips and insight on a number of other topics.

Alexander Haque and Maryam Saboor-Retinad VR-Understanding User Behavior in the VR World

Oct 9, 2018 48:28

Description:

Retinad VR is a company that was born out of a major problem that emerged in the VR industry about four years ago: the inability to measure and understand user interactions, sentiments, and behavior. Alexander Haque, CEO of Retinad, and Maryam Saboor who works as a strategic consultant for Retinad join the podcast today to discuss the acquisition of novel metrics, such as head, hand, and eye movements that produce what’s called a kinematic fingerprint. 


With over 10 million VR headsets in use, the amount of data uptake has phenomenal potential but is too voluminous and messy to be useful unless it can be organized and analyzed in a way that makes sense--and that’s where Saboor’s strategies come into play. So, what insights has the team at Retinad gained so far? To put it simply, part of what they’re learning is what differentiates a good versus a bad user experience with VR. Contrary to the belief that a 360° scene should be enough to engage a user, the team at Retinad has learned that what a user really needs is something that’s not visual at all: audio. 


Hitting users with an audio queue within the first five seconds of a VR experience encouraged them to move around and increased completion of the VR experience by 80%. This is just one of several surprising findings and interesting topics discussed, so tune in for the full conversation. To learn more, visit retinadvr.com.  

Dr. Geoff Rutledge-HealthTap-Physician Advice and Healthcare Guidance at the Tap of a Button on Your Mobile Device

Oct 9, 2018 28:56

Description:

HealthTap was founded about eight years ago with the goal of improving the accessibility of quality healthcare advice, guidance, and the right type of medical care at the right time. With more and more people turning to their mobile devices and an increasing reliance on social media these days, what better platform for a healthcare resource than a mobile application? As the co-founder of HealthTap, Dr. Geoff Rutledge figured there wasn't one, and he's been delighted with the progress and success that he's seen so far. 


HealthTap allows anyone who has a question about their health to immediately receive an answer pulled from the largest library of content from doctors. And if a user has a new or unique question, they can simply submit it and receive a tailored response from a physician within a matter of a few hours--all at no cost. To date, over six billion answers have been provided by doctors via HealthTap.  


Do you need to go to the ER? Should you schedule an appointment with your primary doctor tomorrow? Or would you be better served by scheduling an appointment with a specialist in a few weeks? Many of us find ourselves asking these questions, and until now, not everyone has had a way of getting a quick and reliable answer. And this is just the first level of guidance provided by HealthTap; once a user has been directed to the right level of care, HealthTap will guide them through the process of actually receiving that care.


With over 140,000 doctors signed up on the HealthTap platform and several on call in 47 states, users can find some peace of mind in knowing that with the tap of a button, they can speak with a physician in less than one minute. This is unlike anything that’s been done before and holds great promise for patients and the healthcare industry in general--not just in this country, but around the world. Tune in and visit healthtap.com to learn more. 

Energy Evolution – Brian Curtis, CEO of Concentric Power – The Future Is Now. Sustainable Energy Makes Its Way Forward Into the Power Grid

Oct 4, 2018 18:29

Description:

Brian Curtis, CEO of Concentric Power (concentricpower.com), delivers an informative overview on the technology, sustainability, and efficiency issues that impact the energy grid we rely upon. Curtis has more than 20 years of experience in a wide range of skilled areas such as engineering, finance, and strategic management in the energy and technology industries. He has a wealth of international experience and has partnered with many companies on multiple projects. Curtis was involved with notable projects in China such as the building of an ammonia processing plant in which he stayed on as plant general manager during the launch of their business and product line and as a venture partner with VC firms where he supervised clean energy investment strategies. Additionally, he worked closely with the U.S. Department of Energy with the Office of Energy Efficiency and Renewable Energy, as well as many other clean energy startups. He has extensive experience as a power plant design engineer and as a refinery engineer.


Curtis founded Concentric Power in 2011 to focus on sustainable infrastructure and energy independence for companies in critical industries such as food and pharmaceuticals. Concentric Power is his second start-up. He holds a B.S. in mechanic engineering from UCLA, where he specialized in electro-mechanical systems design and control. Additionally, he holds an MBA from MIT.


As Curtis states, Concentric Power’s primary focus is on sustainable infrastructure for agriculture and industry applications, essentially firm power applications such as natural gas, battery storage, etc. coupled with renewables. Curtis discusses the traditional grid and the sources of power that exist based on geographical locations. And he explains how the trend will be to utilize energy sources that are localized, and how that will affect the power generation and supply overall. He discusses hybrid technologies and the impact on the environment, and his interest in how the technologies are coming together for more efficient energy production that may be greener and more sustainable overall as well. 


The energy engineering expert provides an analysis of the shortcomings of intermittent power sources such as wind and solar, and the battery storage, pumped hydro, thermal, and other technologies that are needed to store intermittent sources for those nonproductive times. Curtis provides his expertise and insight into some of the issues that could present ongoing problems in the energy sector as renewable sources become more mainstreamed, such as the software and control of the systems. He discusses the complexities involved with running a coordinated system of varied energy sources, and how Concentric Power has developed a software program that utilizes machine learning to assist with the management and coordination. He provides information on the costs of energy production in various locations, from high to low, and the importance of smart components to work with the next generation grid as the energy production advances continue to move ahead.


Additionally, the energy expert discusses the details of efficiency and ways that energy producers can make savings along the way and be more productive and successful. He outlines some other projects that he and his team are working on that relate to the grid, such as microgrid projects that deal with renewables and sustainable energy production.

Digital Details – Robert Hernandez, Associate Professor of Professional Practice, Digital Journalism Professor, USC Annenberg School for Communication and Journalism – The Intersection of Journalism and Virtual Reality

Oct 4, 2018 35:17

Description:

Robert Hernandez, associate professor of professional practice, and digital journalism professor at the prestigious USC Annenberg School for Communication and Journalism, provides a delightful overview of the future of immersive digital journalism. Robert Hernandez’s skill and experience covers a multitude of areas such as changing news industry ethics, information and communication technologies, new media, online journalism, pop culture, the practice of journalism, and social media as it pertains to journalism.


Hernandez is a veteran of web journalism with a strong focus on the nexus of technology and journalism. His primary goals are to empower people, increase opportunities for better informed reporting and storytelling, to engage the community, improve overall distribution, and increase revenue. Hernandez’s belief is that ‘open source’ shared knowledge between journalists will improve the quality of journalism, and he continually works to build communities of digital journalists and technology-oriented writers. He is an active participant and supporter of VR journalism and media diversity. Hernandez has served on many national boards such as Chicas Poderosas, InquireFirst, the Online News Association, and the National Association of Hispanic Journalists.


Hernandez has worked professionally on several top projects that are heavily involved with augmented reality, as well as wearables/google glass and virtual reality. His latest project is an immersive experience that is appropriately named and trademarked as, JOVRNALISM™. His project work has been featured in The New York Times, on NBC, NPR, and in USA Today, and other significant publications and media outlets.


Hernandez discusses his professorial work with the Oculus platform, 360 video, and how many make the transition soon after working with 360, to VR. For as Hernandez explains, 360 is more common in newsrooms, and due to economics it has a wider reach. He explains the 360 camera in detail, in regard to framing of the story and the composition, and how he relates this important information to his students. As he discusses, the 360 camera becomes almost another subject in the reporting, as it is a thoroughly immersive experience.


The technology journalism professor gives an overview of some of the advanced technological platforms that are launching on YouTube and other media that allow users to split views and utilize VR tools such as Google Cardboard to essentially go inside the video, for full immersion. However, as Hernandez explains, the technology is so shockingly interesting that first time users may be distracted by the amazing experience, so much so that they may miss key elements of the actual story being told. But he states that a good story will resonate with people, regardless of the technology, for that is the key to solid journalism.


Hernandez recounts a particular experience in which he covered a coming storm and how the graphics and semantics, coupled with the advancing VR technology, provided reference points to help people understand the scale of the storm to fully grasp its potential danger. He discusses how immersive experience helps people to more fully believe the story, but cautions that those with nefarious intentions could use the technology to manipulate as well.


Hernandez’s JOVRNALISM has received multiple awards from respected institutions such as the Online News Association, Society for News Design, and Association for Education in Journalism and Mass Communication, and others.

Chuck McGraw - Chief of Operations at TLDR Capital-The Importance of Centralized Planning and Decentralized Execution in the Corporate World

Oct 4, 2018 26:02

Description:

Having had a 20-year career as a US Navy Seal, Chuck McGraw brings invaluable qualities and insights to his role as Chief of Operations at TLDR Capital, a company that focuses on advisory services in the blockchain industry and fields of cyber and physical security. While managing the day-to-day operations carried out by the globally distributed and decentralized team at TLDR Capital, McGraw focuses on identifying and implementing procedures and processes that are agile and resilient enough to withstand an ever-changing external environment, which is something that his training as a Navy Seal well-equipped him to do. 


Decentralization is a concept that’s increasingly being applied to real-world operations, but what does it really mean? What’s the difference between a team in the traditional sense and a decentralized team, and what are the benefits of the latter? McGraw explains it with a simple phrase: “centralized planning, decentralized execution.” While centralized planning involves all members of a team coming together to develop a plan under a shared understanding of the vision, mission, and objectives of the company, decentralized execution involves allowing individual members of a team the authority to make autonomous decisions in order to carry out that plan. 


Among other topics, McGraw discusses the problems that hinder corporate growth and the productivity of decentralized teams and lends advice to entrepreneurs looking to form their own companies. Tune in for the full conversation, reach out to McGraw through his LinkedIn page, and visit tldr.capital to learn more. 

Lyron Bentovim-The Glimpse Group-Fostering Innovation and Creativity in an Ecosystem of Like-Minded Entrepreneurs

Oct 4, 2018 25:17

Description:

There are at least two main challenges facing entrepreneurs today: finding a solution to a problem in the world that has not yet been effectively addressed, and obtaining the money and know-how to actually build a company based off of that solution. According to Lyron Bentovim, the second challenge stymies the creativity and innovative thinking that the first challenge requires, and as the CEO of The Glimpse Group, he’s working to change that. 


The Glimpse Group is a platform company currently hosting 10 fully-owned startups that have the same or similar goals, the same level of technological understanding, and a shared desire to work collaboratively in developing augmented reality and virtual reality products. While creativity and innovation flow freely in this environment, the team at The Glimpse Group takes care of everything else--from the operational and business development aspects of building a company, to capital raising and management--so that the focus on building and taking products to the market remains unhindered.


This is something that’s never been done before, and it’s taking off incredibly well. Tune in for all the details, including what exactly The Glimpse Group looks for in taking on new startups, visit <a href="http://theglimpsegroup.com">theglimpsegroup.com</a> to learn more, and reach out to Bentovim at lyron@theglimpsegroup.com.

Michael Singer-BrainScope-An AI-Based, Handheld Device for Objectively and Reliably Assessing Traumatic Brain Injuries

Oct 4, 2018 19:07

Description:

In the US alone, approximately five to 10 million people require a brain injury assessment and potential intervention every year; globally, that number rises to somewhere between 75 and 100 million. These numbers may shock you, but what’s perhaps even more shocking is that as it currently stands, brain injury assessments are highly subjective, relying more upon a particular clinician’s capabilities and experience with diagnosing brain injuries than on any form of objective measurement. This has not only led to misdiagnoses, but an extreme overuse of CAT scan technology. 


Michael Singer is the CEO of BrainScope, a company that’s developed an AI-based, non-invasive, handheld device capable of helping clinicians objectively and reliably determine whether or not a patient actually needs a CAT scan to look for bleeding in the brain, and identify whether or not a patient has suffered from a functional brain injury, such as a concussion, which is something that CAT scans can’t do.  


Developed in coordination with military and clinical partners, the BrainScope device is applied to a patient’s forehead in order to measure the electrical activity in their brain and provide as assessment as to whether or not the patient is at risk of a bleed in the brain, and whether or not the patient has suffered a concussion. As a whole, this device provides a panel of capabilities that allow clinicians to feel more confident in making decisions about what’s best for an individual patient. 


Tune in for all the details about this exciting new technology, and visit <a href="http://www.brainscope.com">www.brainscope.com</a> to learn more. 

Insuring the Future – Andrew Hubbard, CEO of Ai-London – Strategic Solutions for Insurance and Investment Strategies

Oct 3, 2018 27:28

Description:

Andrew Hubbard, CEO of Ai-London (ai-london.com), delivers a thorough discussion on the many new tools that businesses and individuals can utilize to expand their use of cloud service-based technologies for investment, insurance, and beyond. Hubbard’s realization that people of all ages and backgrounds wanted to engage with insurance companies digitally drove him to push Ai-London to solve the problem and open up new avenues for discovery. Hubbard explains how the information and policies were once completely geared toward underwriters, insurance agents, and claim specialists, but was woefully lacking in the digital and mobile arena. He talks about how Ai-London seeks to move core systems into the cloud in order to truly innovate and turn the industry on its ear.


Ai-London is a strategic management solutions company that works with life, savings and investment providers who seek to place customers directly in the center of their strategies and systems. Ai-London offers software assets, process and project management skills for business, as well as a full range of technology support services. Hubbard’s company focuses on four primary performance areas: organizational efficiency, digital transformation strategy, line of business convergence, and customer experience. And the company seeks to offer strategies that focus significantly on the management of risk. 


Ai-London offers multiple software options that deal with policy administration, customer-based compliance, and innovation. Their Ai-PAS system that deals with policy administration are an end-to-end comprehensive system that covers the lifecycle of the policy. It offers web services, batch management, product configuration and more that provide for an optimized business model and successful business results as they pertain to current and future investments. Their Ai-CXP system (customer-centric and compliance-conscious) establishes secure records for customer engagements with a focus on the insurer/customer transaction. And their innovation software, Ai-LAB, is an advanced incubation platform for firms that desire to engage in digital and social media type initiatives. It encompasses many digital insurance products, such as those that are social media oriented or short-term, utilizing blockchain.


By innovating and reinventing the social media aspects of investment and savings opportunities, Hubbard outlines how his company is helping to launch many investment strategies and situations that help not only businesses but everyday people who may want to help friends and family or social causes. Hubbard details the ways blockchain has expanded opportunities for many transactions and how industries are excited to begin using blockchain as it offers careful recording of information that is secure. Hubbard states that from an industry point of view, sponsoring independent innovation hubs is a means to break through the barriers to adopting blockchain, and AI.


The technology innovator discusses some pitfalls and issues that may develop in the use of AI as it pertains to his industry. And he details some of the successes of his company’s platform, AI LAB, as the technological advances of cloud services expand and develop. 

Technology Acceleration – Warren Katz, CEO of Techstars – How Tech Startups Choose Their Partners, Develop Their Technologies, and Launch Products

Oct 3, 2018 29:20

Description:

Disclaimer: "<strong>The opinions stated herein are those of Warren Katz, and do not reflect the position of the US Air Force</strong>."


Warren Katz, CEO of Techstars (techstars.com), provides a detailed analysis of the current state of technology startups, and the assistance his company can deliver to steer them in the right direction, help them reach their goals, and launch their products faster. Warren Katz is the managing director of Techstars Autonomous Technology Accelerator with the US Air Force, a partnership designed to increase active engagement between promising startups with state-of-the-art counter-drone technologies, and the Department of Defense.


Katz was President of Neurala, a top artificial intelligence company that is focused on AI with continuous learning. Additionally, Katz co-founded MÄK Technologies, which was later acquired by VT Systems of Alexandria, Virginia. Katz is a mentor to many industry leaders as well as an angel investor who notably invested in Harmonix, GrabCAD, Neurala, Oblong, Bevi, LovePop, and PetNet. He holds bachelor’s degrees in both mechanical and electrical engineering from the prestigious Massachusetts Institute of Technology (MIT).


Katz discusses his work with the US Air Force to help them keep pace with emerging commercial technologies. But beyond the US Air Force, many private sector companies are also looking to Techstars to accelerate their connections to the latest technology. Techstars’ team combs through thousands of startups and selects an elite group of the most viable and commercially relevant, that are either currently manufacturing or about to manufacture groundbreaking technology. After the selections are made, Techstars vets those selected and assists them with advanced development toward their launch. Techstars is the worldwide network that helps entrepreneurs succeed while helping companies access the technology they need. And Techstars Corporate Partners provides powerful industry expertise by offering hands-on mentorship, as well as strategic business development, and access to abundant resources to help startups accelerate their overall progress toward their goals. And with 150 countries involved, 10,000 mentors, and 300,000 alumni, it’s clear that valuable connections are being made.


The technology expert discusses some of the hard problems that the Department of Defense (DOD) faces in its struggle to bring the best tech on board. He states that while the DOD has big pockets, their money does not flow as easily as some private industry companies, and the wheels for progress are often slower moving. For these and other reasons, Katz states that many of the best tech startups are choosing to work in the private sector to avoid headaches and to accelerate their progress. Thus, Katz is helping the US Air Force to streamline their process, to make it easier for the best and brightest startups to say yes to working with them first. By combining outside money with the startup, the DOD can accelerate their process as well, and be less drained financially as two separate teams are working to advance the technology and deliver robust products.


Katz gives an overview of some of the most exciting technology startups that he is working with. From blockchain advances to invisible ink and specialty drones, the technology products are diverse and offer amazing advances for the public and private sector. He discusses drones that attack other drones, technology that can map cellular and WIFI signals and locate unauthorized or enemy equipment, drone-based radiation detectors, and more. As technology and autonomous products continue to advance, Katz expects to see many probes and unmanned devices taking their place on the battlefield and in the private industry world as well.

Snow Sayonara – James Albis, Founder and CEO of SnoHub – Rethinking and Improving the Massive Snow Removal Problem Through an Innovative Technological Solution

Oct 3, 2018 22:39

Description:

James Albis, founder and CEO of SnoHub (snohub.com), provides a complete overview of the snow removal business and how his company’s digital app is creating jobs and helping to alleviate the snow problem that faces millions of people annually. As a boy, Albis saw an opportunity in snow removal. Teaming up with a neighborhood friend when he was just ten years old, Albis shoveled many driveways in the winter and earned a decent amount of extra cash, enough to make a ten year old pretty pleased. Fast forward many years and Albis, now a businessman, found himself pondering why snow removal was still a continual problem for so many people living in areas that get pounded by the winter weather annually. His desire to solve this problem motivated his launch of SnoHub.


SnoHub is a fully automated snow clearing service that, finally, solves the snow-clearing crisis in a super convenient, easy way. It’s a simple to use app for customers and contractors alike that benefits everyone. Snow clearing is no longer difficult, for as Albis states, SnoHub has solved an inefficient problem through the use of mobile technology. Albis explains how their service covers the full range of customers’ needs, from snow blowing to snow plowing, snow shoveling, and deicing. It’s a compulsory, gig economy type of service as Albis explains, and his app solves the problem by bringing literally thousands of new snow removal workers into the solution. From a person with a truck and pro equipment to the college student with a good shovel and strong arms ready to work, SnoHub brings every willing body into the snow removal equation when they are needed!


For customers who need snow removal, SnoHub offers the benefit of easy contracts with no long-term commitments, easy ordering of the service on demand, preorders for when you know the storm is coming, order tracking, and full documentation of completed work with before and after photos. Additionally, SnoHub can alert customers via SMS and phone contact, and their advanced secure channels allow for concise, convenient, and confidential communication throughout the entire process from early ordering all the way through to a final tip to the contractor for a job well done.


For contractors, the benefits are also plentiful. Contractors who work through SnoHub can reserve jobs, up to five at a time in advance of a coming storm or during the storm. They can receive bonuses for meeting specific SnoHub goals, which could put extra money in their pocket. Contractors benefit from the same easy means of communication, via phone or SMS notices. They can view jobs in advance, calculate their time and distance to jobs, and earn extra for completing additional services clients may request, and count on easy payments for their hard work in just three to four days after completion.


Albis discusses some exciting partnerships that he is bringing SnoHub into, such as equipment providers that SnoHub’s contractors can utilize in their work. And Albis stresses his desire to work with American companies as SnoHub strives to bring more workers into the snow accumulation problem through the creation of many viable job opportunities. And for the future, Albis hopes to broaden his company’s services, as they have the database of customers who will probably also need additional services during the non-winter months as well.

Space Spectacles – Payam Banazadeh, Co-founder and CEO of Capella Space – The Advanced Radar Satellites That Are Dramatically Improving Global Surveillance

Oct 3, 2018 27:35

Description:

Payam Banazadeh, the co-founder and CEO of Capella Space (capellaspace.com), shines some light on the important topic of satellite surveillance. Banazadeh’s company, Capella Space, is a venture-backed Silicon Valley company that builds satellites capable of imaging earth day and night, in all weather and light conditions. Banazadeh was named to the prestigious Forbes 30 Under 30 list in 2017 and Capella Space has been touted by The New York Times, Bloomberg, and Inc. as one of the top-25 disruptive companies in the world. Banazadeh graduated magna cum laude with a B.S. in aerospace engineering from The University of Texas at Austin. 


During his time at UT, he received the Texas Outstanding Scholar & Leader Award for his formidable academic skills, performance, and exceptional leadership. Additionally, he holds a graduate business degree from Stanford University. Banazadeh received the NASA Mariner Award for his work on two multi-million dollar missions and the prestigious NASA Discovery Award for outstanding achievement in the formulation of novel concepts for the development of projects for NASA. 


Banazadeh co-founded Capella Space with William Woods with the common goal of developing a means to monitor the planet more accurately and efficiently from space, which could have far-reaching applications for multiple industries. He discusses the frustration they shared as the world watched the unsuccessful search for Malaysian Airlines Flight 370 on live TV. Banazadeh and Woods collectively felt that there should be a better way to monitor the planet, and track objects such as airline flights, etc. He discusses some of their initial findings, reasons behind the ineffectiveness of satellites, such as satellites’ inability to monitor in a comprehensive manner during cloudiness or darkness. 


He describes how traditional satellites utilize optical imaging, which cannot see through either—clouds or darkness. Capella Space’s satellites use Synthetic Aperture Radar (SAR) to achieve their excellent capabilities. SAR is a type of radar that can create 2D or 3D images of objects, such as landscapes, and it uses the motion of the radar antenna over a specific region to provide a sharper spatial resolution than traditional beam-scanning radars. Clouds and nighttime are no longer an issue, or a problem, with Capella Space’s advanced technological satellites.


Banazadeh gives a detailed explanation of the power and energy necessary to bounce satellite signals with the SAR system, and how Capella Space’s satellites inhabit lower orbits to facilitate the power/energy and distance issues. He provides details on the measurements and imagery that exist with the SAR-based satellites versus traditional satellite technology that has been utilized in the past. He talks about the minute details that are visible with their company’s offerings in the satellite technology arena, such as reflectivity, texture, and moisture information that is incredibly helpful for applications in many industries. 


Banazadeh states that their strategy is not to observe the entire globe but to look at important, key areas globally where changes are occurring, changes that could severely impact security and industry. Capella Space’s satellites can identify and classify most objects that are one meter or larger in size and can be accessed anywhere in the globe at any time, day or night. Additionally, they provide new imagery hourly and can easily penetrate clouds, fog, pollution, haze, and nearly every atmospheric condition. And with penetration and accuracy at such a high level, it’s clear why Capella Space is attracting attention and praise for their outstanding leadership in global surveillance. 

Isaac Dallas, Co-founder and CMO of XSPACE – The Changing Marketplace and the Power of Virtual and Augmented Reality in Sales

Oct 3, 2018 23:42

Description:

Isaac Dallas, co-founder, and CMO of XSPACE (xspaceapp.com) provide an overview of the future of product content generation for ecommerce, and how augmented (AR) and virtual reality (VR) will play a significant role. As co-founder, Dallas is intently focused on using visualization to simplify business. In addition to his work in the business arena, Dallas is a strong advocate for education reform initiatives and was a key player in a strategic Harvard and Apple sponsored project that seeks to create advanced programs to assist children with problem-solving skills and strategies for learning. Dallas is a graduate of Illinois State University where he specialized in marketing analytics.


Dallas’s company, XSPACE, provides a simplified end-to-end solution for product information and visuals. XSPACE’s platform ensures that businesses continually provide high-quality images and product descriptions to their customer base. The XSPACE platform will help your brand cut costs, save time, and give customers exactly what they want and need to make a purchase. XSPACE delivers an updated database of products to business websites and streamlines the product management process through their efficient and affordable solutions.


Dallas describes their platform’s automation and the benefits and savings of automating. By introducing an efficient way to deliver 360-degree photography to businesses, customers have greater control over their shopping and buying experience, for about the same cost to a business as their average spends on traditional 2D photography. The platform could contribute to significant savings over the long run, sometimes as much as 70%, and value-added options of 3D, AR, and 360 capabilities will help to build brand trust with customers in the marketplace. 


Dallas discusses the next wave of product marketing and the technology that will continue to impact how customers consume. He provides detailed information on browser issues, and viewing options that are available for presenting product displays online. The online and display marketing expert delivers an analysis of available market data that provides insight into average sales increases, as well as the dramatic decrease in product returns. 


He explains the tremendous upside for sales that exist as businesses convert their inventory to more experiential imaging. For example, in regard to furnishings, as consumers can look at multiple products in a room, they are then more inclined to purchase all of their individual furnishings through the very same store. From sizing, to mix and match options, it’s clear that 3D, AR, and VR are providing unique customer experiences that boost revenue. 

Craig Emmerich- The Complete Guide to Success on the Ketogenic Diet- Reversing and Significantly Reducing the Symptoms of Common and Chronic Diseases

Oct 1, 2018 18:38

Description:

“A lot of what ails us comes from improper inputs...food, how much light we get, how much exercise we get, how much sleep we get...if you can get your environment and diet right, you can reverse some disease processes and greatly improve symptoms of other disease processes,” says Craig Emmerich, founder of keto-adapted.com and author of Keto: The Complete Guide to Success on the Ketogenic Diet, Including Simplified Science and No-Cook Meal Plans. Having been on the ketogenic diet for 12 years now, Emmerich can speak first-hand about the progressive improvements in his health, as well as the challenges faced by many who are just starting out. 


The Keto-Adapted program has received over 1,000 testimonials from clients who have seen significant improvement in their disease processes and symptoms after adhering to the ketogenic diet, including those who suffer from MS, Parkinson’s disease, IBS, acid reflux, eczema, and diabetes. Several people with MS and Parkinson’s disease have reported such significant improvements in their symptoms that they’re no longer dependent upon any medication. And of course, the ketogenic diet carries with it the added bonus of weight loss. 


Tune in to hear Emmerich discuss some of the highlights from his book, such as the three phases of keto, as well as the most difficult aspects of starting and sticking to the ketogenic diet (and some tips on how to do so successfully!) Check out the blog at <a href="http://mariamindbodyhealth.com">mariamindbodyhealth.com</a> and learn more at <a href="http://keto-adapted.com">keto-adapted.com</a>. 

Ken Church- nScrypt- Innovations in 3D Print Electronics, Bioprinting, and Biologics

Oct 1, 2018 29:11

Description:

In recent years, the idea of merging 3D printing with print electronics has become an area of both interest and skepticism. It is feasible, or is it just a gimmick? As the CEO of nScrypt, Ken Church set out to prove that it’s not only feasible, but applicable and relevant. In order to do this, the team at nScrypt is designing and manufacturing industrial printers that will be capable of producing the products we use everyday. But that’s not all, they are also printing biological materials such as collagen and red blood cells. This will pave the way for the printing of more complex tissues and organs, and will relieve biologists of the technological burden of the printing process and the software that’s behind it. 


Most recently, nScrypt has began working with a new startup that’s using pancreatic cells to create spheroids, a biologic drug that has already shown to lower blood sugar levels in mice from 600 to 120 when administered subcutaneously. Church discusses a variety of topics, including thermoplastics in 3D printing, the steps involved and the challenges to overcome in printing organs, and nScrypt’s plan to have careful experiments conducted on the bioprinter in the international space station, which is set to launch February 2019. 


Tune in for all the details, and visit <a href="http://www.nscrypt.com">www.nscrypt.com</a> to learn more.

Victoria Field-Epigenix and KetoPet- Implementing Ketogenic Diet Therapy with Canine and Human Patients Alike

Oct 1, 2018 31:23

Description:

Victoria Field began researching the ketogenic diet and understanding it as an underutilized tool in medicine and science after seeing the amazing results it had on her epileptic dog, who had previously been on anticonvulsants for years without good results. When a simple change in diet relieved her dog of seizures and replaced the medication altogether, she began wondering what other types of diseases a ketogenic diet could help manage--not just in dogs, but humans too. 


In 2014, KetoPet sanctuary was established with the goal of rescuing and improving the quality of life of dogs who have been diagnosed with cancer. With the implementation of a ketogenic diet, they’ve seen a 55% success rate in extending lives past prognosis. They also focus on educating the public on species-appropriate foods not often found on pet store shelves, and providing people with tools for easy implementation of ketogenic diets. One such tool is the KetoPet calculator, which is available on ketopet.org and helps owners develop tailored ketogenic diets based on a variety of factors, including the overall goal they wish to achieve and the state at which their dog’s disease has progressed.  


Geared with the knowledge and evidence gained from the work done at KetoPet, the team at Epigenix decided to apply the same principles to the world of human health and medicine. The team at Epigenix is currently partnering with oncologists to explore the effect of combining ketogenic diets with the standard of care for patients suffering from cancer, and the results from pilot studies have been incredibly positive; within just four weeks of adhering to a ketogenic diet, one patient had regained the ability to speak and read. 


Field discusses the importance of taking a dynamic approach to treating diseases in humans and animals, the importance of empowerment that is provided by nutrition-based therapy, and the upcoming Metabolic Health Summit conference, an organization which she is proud to be named co-founder. The conference is open to anyone interested in learning more or getting started on a ketogenic diet, as well as scientists and physicians looking to hold clinical trials to more thoroughly analyze its effectiveness. Find all the details about the conference at <a href="http://metabolichealthsummit.com">metabolichealthsummit.com</a>, and learn more about ketogenic diets at <a href="http://epigenixfoundation.org">epigenixfoundation.org</a> and <a href="http://ketopet.org">ketopet.org</a>.

Sports Investment – Ben Godfrey, Founder & General Partner of SportVEST – How Blockchain and Tokenization Are Breathing New Life Into Sports-related Businesses

Oct 1, 2018 35:46

Description:

Ben Godfrey, founder, and general partner of SportVEST (<a href="http://sportvest.io">sportvest.io</a>) delivers an overview of sports investing in a digital blockchain world. Godfrey manages the vision and direction of SportVEST with a focus on accelerating the company’s market share and SVE token valuation. He is an innovation expert and has a track record of strong customer relationships, partnership building, and smart staff development and hiring practices for the sports and blockchain communities. Godfrey is especially interested in promoting the investment pipeline for the best visionary opportunities within the sports sector. He brings over 20 years of solid experience in global finance and investments to SportVEST and has worked for some of the top financial institutions such as Deutsche Bank, HSBC, Merrill Lynch, and others.


Godfrey’s company, SportVEST, is a blockchain-based venture capital fund that invests in the future of sports with the goal of creating a novel asset class. Godfrey discusses how he was curious as to why there were seemingly so many great sports business and technology concepts that were having trouble raising funds, and how he set out to create improved fundraising protocols through an innovative venture investment platform. The SportVEST venture fund uses tokenization. SVE is an asset-backed ERC20 digital token built on blockchain technology with token holders forming limited partners in the fund. The SportVEST mission, at its core, is to provide improved VC measurement tools while also bringing better liquidity to investments in the sports sector such that the SVE token holders can decide on the optimal time to acquire profits. And as Godfrey states, the sports economy is valued at approximately $600 to $700 Billion, thus the need for capitalization for sports-oriented startups within the sports economy is immense.


Godfrey discusses the benefits and advantages of utilizing blockchain and tokenization for investment as opposed to traditional investment platforms. Godfrey explains that when you sell the token to an investor, the token represents a share in your fund, but liquidity is a big difference, as investors can get in and out in about one year. This is a significant upside for investors who don’t want their funds tied up in investments for three to five years as is required by many traditional investment platforms. 


The blockchain investment expert provides an analysis of the various areas of the sports economy such as clubs, teams, athletes, merchandise, memorabilia, fan content, wearables, media, IP, data, gaming, AI, VR, fantasy sports, ticketing, events, and gambling, etc. And he discusses how some companies in the sports industry and economy are able to move more efficiently by working through this future-forward platform. And as Godfrey explains, the ease of their investment strategy is another advantage for interested investors. Godfrey details how his company not only helps these sports-focused companies with the investment side, but they also provide hands-on support for growth revenue streams, development, scalability, and more.


The investment expert explains the process for registering, from thoroughly vetting the white papers they provide to contacting the general partners for investment contracts. He explains the importance of transparency in the process and how they take special care to ensure that each investor fully understands all the details every step of the way.


Georgios Depastas, Co-founder – The Constantly Accelerating Field of Data Security in the Digital World

Sep 28, 2018 25:55

Description:

Georgios Depastas, co-founder and business lead of Kalepso (kalepso.com), imparts technology-based wisdom on the value of data security and his goal to keep private, sensitive data safe for all of us. Depastas holds a master’s in electrical and computer engineering from Greece National Technology University of Athens, and a master’s from Cambridge University. His experience in real-time data analytics at Barclays motivated him to launch his company, Kalepso.


Kalepso offers the strongest dynamic encryption at rest, in motion, and in memory. Their platform utilizes machine learning to optimize queries execution, and differential privacy to perturb the query result size in order to avoid communication volume leakages. And their oblivious RAM re-encrypts database rows each time data is queried, to avoid access pattern leakages. Kalepso uses military-grade protocols, at the lowest level for individual records encryption.


Depastas discusses their cloud database system, which allows companies to use their data as they always have, but with significantly more security. He provides information on how the Kalepso platform delivers protection against all attacks, even potential quantum attacks. Depastas outlines how Kalepso’s protection is through dynamic encryption, and how each additional query triggers re-encryption, for maximum security and protection. By utilizing differential privacy and introducing ‘noise’ to the query results, so potential hackers or data thieves cannot infer sensitive information that needs to be critically secured. Depastas lists some of the most current encryption levels and the security variants with quantum computing.


The data security expert gives his opinions on blockchain and its many uses, such as immutability, and how he expects blockchain’s robust, tamper-proof qualities to be utilized in Kalepso’s next line of technology and products. Depastas discusses the expense of storing volumes of information on the blockchain, and the fragility, in terms of blockchains that are not quantum resistant at current. And he mentions how authorization issues will be an area where blockchain can be of use for Kalepso. Depastas states that their current platform has been peer reviewed and undergone white hat hacker testing, and none of the hackers were able to find any vulnerability in the system or their core technology.


Depastas discusses the alpha and beta versions of their Kalepso security products and their upcoming collaboration with the National Bank of Greece to roll out a new proof of concept. And as they expand they will be seeking to introduce more products to the market and continue their global outreach. Cybersecurity is a complex issue and there will always be challenges ahead as Depastas and his team innovate to meet the needs of individuals and businesses.

Sahil Gupta, Co-founder, Product Lead, Soundskrit —The New Technology That Is Improving Audio

Sep 27, 2018 23:37

Description:

Sahil Gupta, co-founder and product lead of Soundskrit (soundskrit.ca), delivers an engrossing overview of the future of audio and microphone technology. Gupta received a B.S. and master’s of engineering in electrical and computer engineering from Cornell University. Gupta worked intensively in the MEMS lab on the DARPA N-ZERO program to develop important zero-power wireless sensors. His standout work received the highest honors in the advanced, elite program and is currently patent pending. DARPA is the Defense Advanced Research Projects Agency. It is an agency of the United States Department of Defense that is responsible for the development of new and emerging technologies for use by the military. And DARPA’s N-ZERO program focuses on two primary areas—unattended sensors (that can monitor a physical environment continuously with near-zero power consumption) and radio receivers (that are always alert for radio transmissions, also with near-zero power consumption).


Soundskrit’s mission is to make audio important, so it will no longer be an afterthought. Gupta states that Soundskrit has developed a microphone that can zoom in on the essential sounds that you deem are most important, in a similar manner to how cameras can zoom in on images. Soundskrit’s microphone separates sounds coming in from various, different directions and provides improved speech recognition in addition to more advanced, higher quality recordings. Their bio-inspired design directly measures particle velocity of sound as opposed to its pressure, and that makes a significant difference. Gupta discusses the scalability of this technology and how it relates to sound quality in terms of frequency. 


As he explains, it is often challenging to gather all the information in the lower frequency range, thus Soundskrit is perfecting ways to enhance the low end. Gupta details the fascinating auditory systems of insects such as spiders, crickets, and flies, and how they use sensors to monitor the air that passes across hair on their bodies, to detect approaching predators. It was this type of intricate insect ability that inspired Gupta to develop Soundskrit’s primary audio technology. 


The audio tech expert discusses autonomous vehicles and other devices that could utilize the technology as it can literally zoom in on sounds to discover their exact source, which facilitates the efficiency of the process for repairing or preventing potential mechanical problems. And Gupta talks about some of the amazing concepts that we could see in the future, such as blended audio—audio that could allow, for example, someone who is walking with headphones to be more aware of incoming sounds that they should hear, such as sirens, etc., for their own safety.


Gupta explains how the technology Soundskrit has developed could be used in many future applications and devices. From smartphone improvements to conference line and meeting room technology, smart home devices and more, Gupta expects to see sweeping changes that will dramatically improve audio and microphone usage. 


Virtual Medicine – Alexis Smirnov, Co-founder and CTO of Dialogue – Visiting Your Doctor Through an App for More Immediate Quality Care

Sep 27, 2018 27:42

Description:

Alexis Smirnov, the co-founder and CTO of Dialogue (dialogue.co), discusses the changing times in regard to healthcare and how virtual healthcare options are becoming more commonplace. Dialogue is the top Canadian telehealth service and Smirnov is passionate about the future of healthcare. Smirnov has many years of experience in the design and development of social analytics systems, search engine technology, conversational mobile apps, and more. He has played an integral role in the building of products and services for various startups and Fortune 100 companies. Smirnov is continually intrigued by transformational technologies and the practical methods to bring them to market, and his passion for tech led him to his work as CTO at Dialogue.


Smirnov discusses how technology is changing the way we receive healthcare. His company, Dialogue, was founded in 2016 by co-founders who saw an incredible need for access to better health care, and they set out to solve the problem via technology. Dialogue offers virtual healthcare solutions for employees, and impactful benefits for businesses and their platform provides forward-thinking, premium, affordable health care options for Canadian companies and individuals. The Dialogue team is comprised of many skilled entrepreneurs, developers, sales experts, designers, customer service specialists, engineers, and quality assurance experts who work collaboratively to devise the best strategies to tackle modern healthcare issues. And their medical team features some of the most highly respected healthcare professionals in Canada who practice virtual healthcare and seek to bring the best care to everyone.


Smirnov describes the problems of traditional healthcare settings in regard to treating patients, and how a virtual care team can alleviate some of the burdens on the system, long waiting times, and more. He describes how many companies will choose to offer virtual healthcare as a corporate benefit, as many employees may find it helpful to have treatment and advice from qualified healthcare workers right on their smartphone… in an app. He discusses the use of photos in the treatment process, such as a skin issue, for example, in which a user could photograph their particular skin issue, send the photo via the app, and get a doctor or health care worker’s advice on treatment right away. He states this method could sometimes allow care to come within minutes, as opposed to days or weeks in a traditional setting. And by cutting overhead through the use of technology, doctors can often reduce their time with paperwork and give more time to patients, which as Smirnov states, is what everyone wants.


Smirnov details how many companies are seeing the benefits of offering this virtual healthcare option to their employees, and as such Dialogue is growing at an incredible rate. He expects that the transition from physical first to digital first healthcare will create a booming industry for virtual care providers. As doctors and hospital administrators learn more about the service, Smirnov mentions that they are always surprised that the system has not been put in place earlier, and they quickly gravitate toward the service as they see that the benefits are boundless.

Scintillating Science – Steve McCloskey, Founder and CEO of Nanome – Nanoscale Scientific Research and The Potential for Groundbreaking Discoveries

Sep 26, 2018 19:18

Description:

Steve McCloskey, founder, and CEO of Nanome (nanome.ai) delivers an interesting overview of their virtual reality solutions for scientists and engineers—solutions that could potentially stimulate discovery of disease treatment and even cure. McCloskey studied nanoengineering at the University of California, San Diego where his work was primarily focused on emerging technologies applied to Science, Technology, Engineering, and Mathematics (STEM). While at UC San Diego, McCloskey worked with Ken Vecchio, the founding chair of the nanoengineering department, as they set the foundation for the Nanoengineering Materials Research Center. They were instrumental in the development of thermodynamic processing methods for iron-based superelastic alloys. McCloskey’s passion for the field led him to launch Nanome as a vehicle to build virtual reality solutions for scientists and engineers working at the nanoscale. Specifically, Nanome’s team spends a significant amount of time exploring protein engineering and small molecule drug development. 


McCloskey’s company, Nanome, transforms our interaction with, and understanding of, science, by providing a virtual world where users can experiment, design, innovate and learn at the nanoscale. McCloskey explains that Nanome’s vision is to create an immersive interface where people can see things intuitively, and better interact with science via virtual reality and other tools. McCloskey states that their current technology allows users to view at the atom level, but he is working to develop further, to achieve success at the subatomic level. Additionally, he discusses the energy minimization force field as it relates to forces that are being calculated between atoms as they push and pull apart. 


McCloskey discusses one of their top products that he is particularly excited about—CalcFlow. CalcFlow allows researchers to study and visualize vector calculus in an interactive environment. The platform enables mathematical modeling, manipulation of 3D graphs, as well as the editing of parameters while you work. He elaborates on the advantages that CalcFlow provides for research and experimentation, such as its ability to bring mechanical engineering design into the dynamic in an observable manner. And the process is exceptionally great for optimization and delivery into the 3D printing environment.


The nanoengineering expert describes how the introduction of blockchain to their platform will allow more people to work globally toward solutions to many problems that humans face, from technology to medical and beyond. McCloskey details how the platform can provide an opportunity for a larger group of people to study and hopefully find solutions for tropical diseases, diseases that big pharmaceutical companies have no interest in, due to the fact that their ability to profit is lower. Through the use of open-source models and automated licensing, and even closed source, the use of blockchain truly is changing the rate of discovery, as the global community can be involved. 


As the technology is expanding, McCloskey expects that virus modeling will become easier, as entire viruses can be viewed with atomic detail, enabling study at the systems level of the biology. And by simulating cells at every level, the possibilities for discovery are enormous.

Kinetic Ketogenic Connections – Dr. Brian Lenzkes, Founder, Low Carb Advisor – The Power of the Ketogenic Diet for Weight Loss and Medical Condition Reversal

Sep 26, 2018 48:37

Description:

Dr. Brian Lenzkes, founder of Low Carb Advisor (lowcarbadvisor.com), details the many advantages of a ketogenic diet and lifestyle. From weight loss, alertness, more energy, and a feeling of general well being, Dr. Lenzkes lays out the undeniable benefits and the science behind the diet that Americans are turning to for good health. As an internal medicine doctor in San Diego, Lenzkes has long been interested in clinical nutrition. His physician group has been in operation since 2004, and when he is not practicing medicine he can often be seen at speaking engagements around the country, discussing modern health. Lenzkes received a BS in Biology at UC Irvine. After attending USC Medical School, Lenzkes completed his residency at Scripps Mercy Hospital in San Diego and was named Chief Resident there before launching his private practice at Internal Medicine Associates. 


Lenzkes discusses his personal struggle with weight gain in spite of following standard medical advice for weight loss. As a physician, Lenzkes was determined to find ways to reduce his patients’ reliance on drug companies by working with them on nutrition and a healthier lifestyle in general. Working from personal experience, Dr. Lenzkes was, and is, strongly motivated to bring the ketogenic lifestyle to his own patients who are seeking nutritional advice, as well as to the general public. Lenzkes provides an overview of the connection between fasting and good health. He talks about the many medical problems that he sees regularly as an internal medicine physician, such as diabetes, cardiovascular disease, fatigue, hypertension and weight gain, and their connection to insulin resistance. He discusses the advantages of cutting out sugars and processed foods and returning to real, wholesome natural foods.


The nutritional expert and respected physician describe the innumerable benefits of the ketogenic diet and lifestyle. The diet offers safe and healthy weight loss, control of blood glucose levels, improved brain function, and the potential to literally reverse many chronic health conditions. The keto diet transitions the body into a fat-burning metabolic state called nutritional ketosis. In nutritional ketosis, the body uses few carbohydrates for energy—it begins using ketones that are produced by the liver from the breakdown of fats. It’s the process of burning body fat for energy by eating the proper foods. He describes the cycle of hunger and eating, and how it is quite often directly related to higher triglyceride levels. A triglyceride is an ester that is derived from glycerol and three fatty acids. He explains that a ketogenic diet will drop triglyceride levels nearly in half in a surprisingly short amount of time, which will lower hunger and even allow for fasting to be tolerated easier. 


Lenzkes delivers an analysis of the effects of carbohydrate loading on the body. He talks about the benefits of higher fat, higher protein diets and how they can actually decrease hunger. Additionally, he expounds upon the growing medical problem with the fatty liver, how the body stores fat, and the carbohydrate connection, as well as what medical experts can do to advise patients on nutrition, to combat the problem. He talks about the paradigm shift in medicine that is coming, in regard to nutrition. Lenzkes gives an overview of his ketogenic program and the many options from fasting to carb cutting and beyond. He discusses the challenges people face when they take on a ketogenic lifestyle, and how variations within the diet may be necessary for people to find the best way to their true success.


Lenzkes states that experimentation is key, as different foods and plans work better for some than others, but the nutritional benefits will be incredibly rewarding once someone finds the plan that works best for them. He discusses how carbs break down into sugar, and the hidden carbs in many foods that people know to be healthy foods even. He talks about how the key to health and fitness is often unnecessarily overcomplicated when the basic tenets of controlling sugar and carb intake are easier to grasp and adopt than many people realize. He details how a drop in insulin level will, in most cases, immediately begin to improve fatigue, mood, cognition, depression, and so much more. Ultimately, as Dr. Lenzkes states, the power exists within us all to change our nutrition habits and reverse potentially dangerous medical issues and conditions, and it is his personal goal to help everyone take steps toward achieving their best health possible.

Dale Pfost-MicroBiome Therapeutics-A Drinkable Blend of Prebiotics to Feed Human Microorganisms and Boost Human Health

Sep 25, 2018 33:07

Description:

During the past decade, the human microbiome has slowly come to be recognized as an integral factor of human health, one that’s been misunderstood for far too long. Whether it’s an autoimmune disorder, diabetes, habitual overeating, a central nervous system disorder, or irritable bowel syndrome, Dale Pfost believes there’s a connection to be found with the microorganisms that live inside each and every one of us. With active research being conducted on this topic, his opinion is backed by evidence and shared by many. 


Pfost now serves as the CEO of MicroBiome Therapeutics, a company founded nine years ago with the goal of bolstering the health of the microbiome in order to bolster the health of people. So, what’s the main contributor to the health of the microbiome, and what do we need to do in order to address it? Pfost believes the number one problem is our diet, something which has changed dramatically over the past several decades; we’re overeating, yet we’re simultaneously underfeeding the microorganisms that enable us to live healthy lives. 


What’s the solution? The team at Microbiome Therapeutics has just launched BiomeBliss, a perfectly formulated blend of prebiotics designed to feed microorganisms the nutrients they need but often don’t receive in sufficient amounts (if at all). Based on the most recent double-blind, randomized clinical studies, BiomeBliss has produced three results: satiety (absence of hunger), increased GI health, and lower glycemic indexes. 


Tune in to learn more about this fascinating new area of research and what BiomeBliss can offer you, and reach out with questions via the website at mbiome.com. 

Eduardo Jorgensen, CEO-MedicSen-Non-Invasive, Predictive Technology and a Drug Delivery System Improving the Quality of Life for Patients with Diabetes

Sep 25, 2018 19:54

Description:

Over 100 million people in the US are now living with diabetes or prediabetes, a disease that causes poor quality of life for most. Eduardo Jorgensen set out to address this problem by establishing MedicSen, a company that’s developing a predictive algorithm capable of alerting patients up to an hour in advance of a hypoglycemic event. 


The MedicSen software receives information from wearable devices such as glucose monitors and is able to predict a patient’s future glucose levels based on certain parameters, such as food intake, activity level, and levels of insulin versus glucose in the body. By alerting the patient without any input aside from food intake documentation, this technology will provide patients with relief from the constant stress and worry that accompanies diabetes. Furthermore, it’s an interactive system, which means that patients can ask it certain questions, such as whether or not it would be safe for them to consume a soda or go for a hike. But that’s not all: currently in the works is a needle-free drug delivery device in the form of a patch. 


Tune in for all the details, visit medicsen.com to learn more, and reach out to Jorgensen at <a href="http://eduardo@medicsen.com">eduardo@medicsen.com</a>. 

Professor Guglielmo Aglietti-Surrey Space Center-Thousands of Tons of Space Debris in Orbit Pose a Threat to New Satellites, What’s the Solution

Sep 25, 2018 33:56

Description:

Over the past several decades, advancements in space technology have led to an unprecedented number of satellites being put into orbit, which has led to a number of exciting new insights and findings. However, it’s come at a cost: with a few thousand tons of space debris from old and nonfunctional satellites orbiting the earth at a rate of about seven kilometers per second, each individual piece of debris poses the threat of colliding with another, or with a new satellite. This is a problem that must be addressed in order to continue using satellites safely. 


Professor Guglielmo is the director of the Surrey Space Center at the University of Surrey in England, and he joins the podcast today to discuss this problem and the ways in which he’s trying to solve it. He explains that when large particles of debris collide with one another, a cascade effect of collisions ensues, worsening the problem. And of course, if a large piece of debris were to collide with a new satellite, the satellite would be destroyed. According to Guglielmo, then, the largest threat is none other than the largest pieces of debris. 


Tune in for all the details about the work that’s being done at Surrey to develop a solution, and the biggest challenge facing the development of that solution. Learn more at www.surrey.ac.uk/surrey-space-centre. 

Software Development and Quality Assurance – Prasanna Singaraju, Engineering Chief and CTO, Qentelli – Improving Business Systems and Applications Through Quality Engineering

Sep 25, 2018 14:51

Description:

Prasanna Singaraju, engineering chief and CTO of Qentelli (<a href="http://qentelli.com">qentelli.com</a>), provides an overview of how Qentelli’s solutions are delivering a new standard in quality engineering and DevOps for Continuous Delivery. Continuous Delivery is a DevOps software development practice in which code changes are built, tested, and prepared for release into production. Singaraju states that Qentelli helps companies re-engineer their applications that are built upon existing, older technology stacks. He discusses how they utilize DevOpps (a software engineering practice that seeks to unify software development and software operation) and automated testing. 


Singaraju has a wealth of experience in radio-frequency engineering and infrastructure, data, communications, quality assurance, and project management. As CTO, he brings a passionate interest in sustainable innovation, application engineering, and value-driven solutions to Qentelli. Singaraju has an illustrious background in his industry and has a strong reputation as an integrator and world leader in IT, product and program management, as well as customer support.


Qentelli’s focus is on the nexus of quality engineering and intelligence, and Singaraju leads their innovations group with an active approach to the design and implementation of the various solutions and products they deliver. The company seeks to offer high-end software development and quality assurance to bring higher level applications to businesses.


Singaraju discusses Qentelli’s goal of assisting companies, with higher speed delivery of applications for their operations. From banking to retail, airlines to restaurants, Qentelli’s solutions are practical and usable for many industries. He provides details of their successful transformations for businesses, and how they are able to improve feedback and increase the quality of applications. Starting with ecommerce all the way through to back-of-store, point of sale systems, to payment, Qentelli delivers end-to-end solutions for business application success.


Singaraju describes many of the problems that businesses face in this space, and how Qentelli’s solutions apply. He states that any business that utilizes applications to serve their customers is a business that they can help improve. Singaraju outlines their multi-level approach, which includes examination of a company’s overall processes, technology, and methods of implementation. And Singaraju details the specifics of bringing real-time, absolute visibility into the quality assessment as a means to achieve predictable outcomes in the overall application lifecycle.

Day Care Demand – Jessica Chang, Co-founder and CEO of Wee Care – The Growing Need for Quality Day Care That Is Motivating Entrepreneurs and Caregivers to Start Their Own Centers

Sep 25, 2018 26:58

Description:

Jessica Chang, co-founder, and CEO of Wee Care (weecare.com), delivers an informative overview of the current state of childcare and how quality day care services are desperately in demand. Chang’s Wee Care Preschool has established a successful early childhood program for children 3 months to 6 years of age. Their comprehensive curriculum provides strong academics, creative play, as well as physical activities, all within a warm, safe, and nurturing environment. Their stimulating, structured program ensures quality interaction between the children and their teachers, as well as child to child. Children can learn valuable social skills as they interact with one another. 


Chang states that Wee Care helps parents find quality, affordable, convenient care. Additionally, they assist preschool teachers, caregivers, and stay-at-home moms who seek to start their own licensed home daycare center, as Wee Care’s online technology platform provides the structure they need to succeed. Chang discusses the rising cost of day care for parents, and also the low pay caregivers often receive, and her concern for all parties involved. Chang’s desire is to solve the problems on both sides. Chang’s, Wee Care, offers best practices advice and support, and assists with setting up the foundation for new daycare center operators. Wee Care can provide structural support to newly formed daycares and thus decrease the administrative time for operators. This allows many who choose to work with Wee Care in this manner to operate their daycare and still have another career.


The Wee Care Preschool environment offers many opportunities for learning new skills during various activities. Group activities, circle time, play time in designated play areas, science centers, and individual teacher/student skill building are all part of the program. Wee Care focuses on pre-math and reading readiness throughout the day at each of the classroom levels. Also, climber time and outdoor play activities provide physical movement and important motor skill development.


Chang gives an overview of the trends in daycare, and she details how more and more women are starting their own businesses. She discusses how technology and the desire to control your own time has motivated many people to seek employment that works for them, on their schedule, by their own rules. Thus, Wee Care is experiencing tremendous growth as individuals are enthusiastically taking on new challenges and opening home businesses. 


The daycare and child development expert provides information on licensing and the standards that new daycare operators must meet in order to be approved. She underscores the advantages of working with Wee Care, as caregivers can focus on what they love, which is working with children and teaching them, while Wee Care handles the administrative obstacles that may seem daunting to some new business owners. She states the importance of curriculum, and how Wee Care takes the stress out of this by providing the curriculum in advance so caregivers and teachers can simply implement it. Finally, Chang outlines the importance of cultural diversity and languages, and how they enrich the learning experience for children overall. 

The Amazing Power of Apps – Ramsay Brown, Co-founder and COO, Boundless Mind – Understanding How The Apps That We Use Impact Our Behavior and State of Mind

Sep 25, 2018 19:09

Description:

Ramsay Brown, co-founder, and COO of Boundless Mind (boundless.ai) delivers an insightful overview of the apps that influence our behavior and the mechanisms of behavioral engineering that could change our actions. Brown believes that machine-learning techniques have advanced to the level that we can now predictably and predictively take behavioral engineering seriously. Brown states that Boundless Mind can help companies understand how people are acting, and change the way they behave. Additionally, they can assist individuals who want to make a behavioral change in their own life. He discusses some options that they offer to help people change the way they interact with social media as well, options that allow people to build healthier relationships. 


Brown and his team at Boundless Mind believe that technology is becoming more addictive, and coercive, and some of the technologies that are moving at the greatest pace toward persuasive domination are unfortunately not always great for human prosperity. Through the study of human behavior mechanisms, Boundless Mind has developed their AI platform such that any app that seeks to help humans thrive can now do just that, powered by state of the art mechanisms that bring together brainpower and machines. Essentially, the Boundless AI platform works to combine neuroscience and data, to deliver tailored in-app user engagement programs that consistently outperform other methods and approaches. 


The AI platform allows administrators to pick a common action that has value for users (opening the app or completing a specific task), and then they can pick a particular enhancement, such as a visual cue that acts as a reward for completing the task. Finally, the users are connected to Boundless Mind’s API through one of their supported software development kits, known as SDKs, or REST (Representational State Transfer) API, which aligns each user onto an individualized program tailored for them. It is software that changes user behavior and strengthens engagement following neuroscience, which has proven that habits are programmable, but individuals require tailored programs.


Brown discusses optimized reinforcement techniques, and their partnership with a large pharmaceutical company in which Boundless Mind has delivered a means to keep patients on track with their medications. By using the mechanisms of basic neuroscience their platform can help to reward patients for taking their medication and thus increase retention. Brown digs into the hard science behind predictability and patterns of reinforcement as it applies to modification of behavior.


The behavioral modification expert provides an overview of how we interact with our apps in the smartphone world, and how all apps are designed to be persuasive. He explains that we are constantly making choices as to which apps we give our attention to, and how those apps are influencing our decisions, and ultimately how we feel about ourselves. Brown believes that when we are equipped with tools that understand our motivations and aspirations, that our smartphones can become instruments that enable us to grow into the kind of people we aspire to become. By loading up our smartphones with apps that appeal to our better selves, who we aspire to be, and deleting apps that impact us negatively, Brown feels that we can transition to a healthier life. Brown’s team ultimately seeks to work with other companies that share their vision of bringing positive, healthy changes to our behavior.

Dr. Bret Scher-My Boundless Health- Transforming Health with Individually-Tailored Programs

Sep 25, 2018 34:44

Description:

Dr. Bret Scher has been a cardiologist for over 15 years now and says that one thing’s been made clear: our health care system is badly broken, failing to address the main issues affecting people and to provide solutions that will actually work. As the lead practitioner at My Boundless Health, Dr. Scher is trying to change this.


“The goal of the work I’m doing...is to help people get access to information that is not being promoted by our contemporary health care system and to get access to a practitioner who can spend more time, think outside the box, and see the bigger picture to really try to find the right solution for each individual,” says Dr. Scher. At My Boundless Health, the focus is on a lot more than just lab results and medications; it’s about nutrition, exercise, stress, sleep, and social interactions. Ultimately, it’s about listening to the patient and making adjustments according to the changes in their life or status of health.


Dr. Scher takes a two-tiered approach by first giving people easy access to as much information as possible, and then working one-on-one with patients in order to develop an intense, individually-tailored program that will best suit their needs. Dr. Scher discusses a variety of topics, including overmedication, the details of the initial screening process of his program, and some of the most difficult aspects of getting people into more healthful states of being. 


Tune in for the full conversation, and learn more by visiting <a href="http://myboundlesshealth.com">myboundlesshealth.com</a> or <a href="http://lowcarbcardiologist.com">lowcarbcardiologist.com</a>. 

William Hurley, CEO-Strangeworks-Quantum Computing for Developers and Laypersons

Sep 25, 2018 34:26

Description:

There’s been a lot of talk about quantum computing lately, but what exactly is it, and what are some practical applications that it may have? These are just a few of the topics discussed by William Hurley, CEO of Strange works, which is a company that launched earlier this year during a South by Southwest Keynote presentation and raised $4 million just in seed money. 


The main goal of the company is to make quantum computing technology more understandable to the layperson and more accessible to developers. Right now, the Strangeworks platform offers developers and enterprises a way to become familiar with the technology by performing quantum experiments, as well as a timeline of the likely advances in this technology. Hurley believes that within 24 to 36 months, quantum computing will be usable and produce real enterprise outcomes.


Quantum computing has come a long way in the past few years, but it has a ways to go. Among many other topics, Hurley discusses what he believes to be the two main factors holding back quantum computing: high cost and the unsolved problem of error correction. Despite the challenges, the potential of quantum computing is exciting and has the potential to change the world. 


Tune in for an informative and compelling conversation, join the community at <a href="http://quantumcomputing.stackexchange.com">quantumcomputing.stackexchange.com</a>, and reach out to Hurley with questions via email at whrley@strangeworks.com.

The Ketogenic Epilepsy Connection – Jade Nelson, Epilepsy Advocate, Health Educator, and Author of My Keto Toolkit – Better Health, Abundant Energy, and Feeling Well with a Ketogenic Diet and Lifestyle

Sep 20, 2018 27:45

Description:

Jade Nelson, speaker, coach, epilepsy advocate, community health educator, and author of My Keto Toolkit, delivers a passionate account of her journey to better health through lifestyle changes and the ketogenic diet. Nelson shares her story and details on her remarkable path to healing at her website (jadenelson.net). Nelson’s book, My Keto Toolkit, is equal parts a survival guide and overview of her path to becoming a ketogenic epilepsy warrior. Nelson shares her 31-year journey with an epilepsy diagnosis, her personal experience with self-care, the ketogenic diet, health insurance and more. The informative book provides tips, resources, and information on favorite products, as well as many personal recipes, etc., that can help people to take the first step toward a healthier life with more energy and a feeling of well being. It is a guide to a lifestyle that will truly be life-changing.


Nelson describes how a strict ketogenic diet worked for her, but that other might achieve positive results from variations on the diet, such as a modified Atkins, or simply a low-carb approach. Nelson describes the incredible changes she felt once she took the plunge into a ketogenic lifestyle, such as feeling more alert, having an abundance of energy, feeling happier, and living with a general sense of wellness within the body. Overall she was simply less emotionally drained, and she no longer needed those daily naps; her life was restored. 


The nutrition authority offers valuable information on the importance of tweaking one’s diet to ensure it is providing the maximum health benefits. She discusses the process of gluconeogenesis, which is what happens when the body receives more protein than it needs and converts it into glucose, which can push someone out of ketosis. Nelson explains that the process of discovery and experimentation can lead ketogenic dieters to a plan that is optimum for them, as everyone is different internally to some degree. She stresses that the ketogenic diet will cause many to feel satiated more often, not as hungry as they might have been before beginning the diet, and the importance of monitoring the diet, especially if one’s body fat is low to ensure that body muscle is not adversely impacted.


Nelson outlines some helpful tips for those who are on the go. She states that there are more ketogenic products available in the marketplace today, including many travel items, oils, and supplementary foods that are grab-and-go and convenient. She explains that there are many ways to supplement meals when eating out or traveling, options that can round out the ketogenic diet and allow everyone to keep on track with their ketogenic routine and stay in ketosis. Additionally, she describes some of the ketogenic products that she has had success with but stresses that it is real food, not products, that is the key to success in a ketogenic lifestyle and diet.


The ketogenic educator discusses ketogenic specifics for women and some of the important issues to consider to ensure that their diet doesn’t adversely affect their natural cycle. She warns that excessively low caloric intake and insufficient nutrients can possibly cause some women to become amenorrheic, which is the loss of their period, so women should be aware, and adjust their diets accordingly to avoid this problem. 


Nelson discusses her path to success on the ketogenic diet, and the many people she has worked with on an individual basis, as well as her coaching and live event speaking engagements where she outlines a wealth of information on the diet and nutrition in general. She encourages people to reach out to her through her website as well as through instagram (@thetraininsideme) and on facebook.

Rideshare Rentals – Kit Tran, Chief Marketing Officer at HyreCar – Solving the Rideshare Vehicle Shortage & Creating Financial Opportunities

Sep 19, 2018 21:08

Description:

Kit Tran, chief marketing officer at HyreCar (hyrecar.com), delivers an overview of the rideshare industry and how his company is helping to build a bridge between drivers and vehicle owners. While many people are excited to get into the potentially lucrative, make your own schedule career of rideshare driving, 40% of those who desire to drive are denied the opportunity because their car simply doesn’t meet Uber or Lyft’s standards. Thus, HyreCar is there to bridge the gap, offering solutions for drivers and vehicle owners who want to work, and make money, respectively.


HyreCar is an app that allows car owners to rent their vehicles to ridesharing drivers who either don’t have a vehicle of their own, or their vehicle fails to meet the standards of their rideshare employer, or they simply prefer to not use their own vehicle. It’s a startup company that brings together a sharing economy model and on-demand economy model that benefits all parties involved.


Tran’s company, HyreCar, was launched as a means to empower entrepreneurs by leveraging technology, and HyreCar seeks to become the undisputed leader in automotive asset sharing. In an on-demand economy, drivers can make one thousand dollars per week or more, so demand for vehicles is on the rise. Vehicle owners who have an extra vehicle to spare, or drive infrequently with the vehicle they do have, can make a substantial amount of money by renting out their Uber or Lyft approved vehicle. In fact, owners can sometimes make $14,000 per year, possibly even more.


Tran speaks about HyreCar’s higher mission, which is enabling people to get on the path to financial freedom. He shares some stories of their successes in this area, as their service has allowed many who were once homeless or underemployed find a solution to greater financial stability. He gives an overview of their service, covering the terms and various background checks that potential drivers must go through in order to work with HyreCar. As HyreCar is a tech platform that is designed to work in tandem with the rideshare companies, HyreCar’s vehicles must be used for ridesharing specifically.


Tran discusses future opportunities for HyreCar and drivers alike, as they continue to evolve to meet the growing demands of the industry. Tran states that their primary goal is to build bridges to financial freedom, and through that lens they look at many potential paths they can take to improve lives and meet demands. He discusses possible opportunities, as drivers or owners may want to expand and create their own fleet of vehicles and thus find even more avenues to financial success. For as Tran states, an easier path to ownership benefits everyone.

Gene Genie – George Church, Geneticist, Chemist, Molecular Engineer, Professor at Harvard and MIT – How Genome Sequencing and Gene Therapy Is Turning Fantasy Into Reality and Helping to Reverse Disease

Sep 19, 2018 36:55

Description:

George Church is an American geneticist, chemist, molecular engineer, professor of genetics at Harvard Medical School, and professor of health sciences and technology at Harvard and MIT. Church provides an informative and thorough overview of his work in genetics and gene therapy, which is the use of genes to treat or prevent disease. Church’s Harvard Ph.D. work included the initial methods for direct genome sequencing, as well as molecular multiplexing and barcoding. His innovative research and experimentation led to the first genome sequence (pathogen, Helicobacter pylori) in the mid-nineties. 


His work has provided important and significant contributions to practically all next-generation DNA sequencing methods and a long list of companies who are leaders in the field. Church’s lab's research on chip-DNA-synthesis, gene editing, and stem cell engineering led to the founding of multiple application-based companies in the areas of medical diagnostics, and synthetic biology and therapeutics. Church is the director of an IARPA (Intelligence Advanced Research Projects Activity) BRAIN Project and NIH Center for Excellence in Genomic Science. 


Church discusses some of the new companies that he is involved with that are researching many scientific areas. He details one of his passion projects that seeks to impact human cells such that they will be resistant to all viruses. He talks about various endogenous viruses that exist within specific genomes, and exogenous viruses, and the methods of his lab is studying, particularly in regard to transplants. He explains that virus and disease transmission is a great concern in organ transplantation from pigs to humans, and how it is important to eliminate all endogenous retroviruses that could potentially cause disease once organs are transplanted. While the concept of animal to human organ transplant is not a new idea, Church explains that it has taken 20 years to develop new technologies for gene editing that can enable simultaneous changes in dozens of areas within the genome in order to make transplantation potentially possible.


The genetic expert talks about current research in the study of longevity and his interest in using gene therapy for the reversal of diseases and conditions such as obesity, type II diabetes, osteoarthritis, heart and kidney damage, etc. He discusses the categories that his lab looks for that can be manipulated, and he provides an overview of classic gene therapy for diseases that someone is born with, as well as the FDA approval needed. He provides examples such as how mitochondria is impacted by aging, and why important levels drop, and how gene therapy can provide a means to restore cells to more optimum levels for better functioning. 


Church expounds upon the current options for genome sequencing and where he expects the advances in genetic research to lead us. He details how the price is coming down such that many people may soon have access to important genetic information that can greatly impact their lives, inform their decisions about having children with partners, and so forth. Church discusses epidemiology, therapies, and methods that apply to genetic research, and how the future will possibly see gene therapy become as commonplace as vaccinations are today.

Technology Treatment – Matt Angle, PhD, Founder & CEO of Paradromics, Inc. – Connecting Computers to Brains to Improve Lives and Reconnect People to Their Abilities

Sep 19, 2018 30:08

Description:

Matt Angle, Ph.D., the founder & CEO of Paradromics, Inc., provides an informative overview of the current state of neuroscience and technology as it pertains to people who have sustained a loss of ability due to injury or disease. 

Angle completed his graduate studies at the Max Planck Institute for Medical Research, a research institute of the Max Planck Society in Heidelberg, Germany. His post-doctoral work at Stanford University was focused on the design of novel interfaces between nanomaterials and cells, with the intention of developing next-generation electrical recording technologies and products for the field of neuroscience.


Paradromics seeks to advance bidirectional data streaming capabilities that flow between brains and computers. Their complex neural interface technologies are designed to help physically disabled patients reorient and reconnect with the world outside. The Paradromics platform brings together research and clinical applications. Angle discusses his team’s work and describes their primary goal, which is to create a modem for the human brain. He describes how blind, deaf, or paralyzed people have been somewhat cut off from the world, and he explains the motivation that fuels his work at Paradromics as his team pushes to find ways to assist these people to reconnect. He details the basic examples of how their technology could work, such as robotic limbs that move based on brain waves for those who are paralyzed, and cameras that provide visual experiences, or input to the brain, for those who are blind. 


The neuroscience expert provides details on brain implants currently in trials that allow up to one hundred electrodes to be implanted into a person’s motor cortex that can give a paralyzed person control of a robotic limb or a mouse on a computer screen, etc. Angle hopes to build a higher data rate version of the current technologies, and increase the advantages that these amazing technologies bring to the lives of those who have sustained injuries and/or losses of function. Angle describes in detail some of their specific technology, and the methods and materials used, such as microwire-based recording techniques. He talks about the impact of the use of microwires, as they are only about one-fifth of the size of a human hair, and thus they can be inserted noninvasively into brain tissue. He states that it comes down to how many neurons can you record and how many neurons can you stimulate. He discusses the value of direct electrical recording and the importance of recording for simplicity of implementation and preservation of safety.


Angle provides his analysis of the importance of the collection of data and how it impacts the simplicity of models that a researcher/designer can use to describe a particular system and build more sophisticated hardware. Angle states that more, and better, data makes an analysis easier, not harder. Finding the simplest models for use in the decoding of brain data will be advantageous for the development of new and innovative products and systems that will enable users to have more control over their world. Angle states that the Paradromics team’s goal is to have a completely implantable device ready to go by the end of the year 2020, with clinical trials beginning as early as 2021. He discusses how their technology may play a part in correcting neural activity to help treat conditions and diseases with electrophysiological signatures such as chronic depression, obsessive-compulsive disorder, or even schizophrenia. 


Angle founded Paradromics in 2015 with a team of skilled engineers and neuroscientists. His company received supplemental early-stage support from the National Institutes of Health (NIH) and the Defense Advanced Research Projects Agency (DARPA), which is an agency of the United States Department of Defense that develops emerging technologies for use by the military.

Anouk Wipprecht, Fashion-Tech Designer – Clothing That Communicates with Our World Through Technology

Sep 19, 2018 22:37

Description:

Dutch fashion-tech designer, Anouk Wipprecht, discusses her work and the many ways that technology and fashion are becoming one. As a successful designer and innovator in the fascinating field of fashion-tech, Wipprecht’s passion is to design garments that bring together the physical and psychological. Fashion-tech is a bridge between multiple areas of study and design and is the nexus between fashion design, science and engineering, robotics, and user experience design. It seeks to lift fashion design to an experiential level, rising above simply garments to be worn for comfort or style. 


With fashion as interface, Wipprecht’s designs push conventional design to higher levels that interact with the surroundings and introduce considerations of expanding technology, personal space, and more. Wipprecht has formed many exciting partnerships with major companies such as Microsoft, Intel, Google, Audi, and Cirque Du Soleil, as well as the 3D printing company Materialise, as she continues to influence how we will dress in the ever-expanding technological future.


Wipprecht discusses her thoughts on the ways she wants fashion to speak for those who wear it and how the technology aspects offer more opportunities for the wearer. She talks about the interesting spider dress that she created while working with Intel and details her use of the Intel Edison, a computer-on-module designed by Intel to be utilized as a development system for wearable devices. The spider dress contains sensors and moveable arms that create a more defined boundary of personal space while pushing style in a new direction. 


Wipprecht describes her smoke dress, a dress that contains a small, battery-operated fog generator. The dress was unveiled at the Dutch Electronic Art Festival in Rotterdam. The famous smoke dress can produce up to a quarter hour of continuous output or 150 puffs of five seconds each, and it can react to the number of people within the general area.


The innovative designer discusses her work with entertainers such as Fergie, Britney Spears, and others, and collaborations with movie studios on CGI-based movies. Wipprecht delivers an overview of the important work she is doing to help children with ADHD, such as her unicorn horn hat that contains a camera and electrodes that helps to measure brain signals and attention. She explains the process and how the camera records when brain signals indicate that the user is paying attention, which helps to further the advancement of their development.


As technology continues to become part of our very existence, electronic systems can now be included in materials that allow processors and sensors to transmit and receive information. Wipprecht’s technological couture is poised to lead us into the future of wearable tech.

Daniel Jones-Aural Analytics-A Low-Cost, Objective Way of Measuring Brain Health Using Machine Learning Algorithms

Sep 18, 2018 24:05

Description:

The current gold standard for measuring and tracking brain health is not only hugely expensive, but time-consuming, invasive and cumbersome for the patient, and not as accurate as it could be. Aura Analytics is a health tech company that’s providing a new, inexpensive, and highly accurate method for early detection and longitudinal tracking in brain health, which encompasses Alzheimer’s disease, Parkinson’s disease, ALS, and other disorders affecting fine motor and cognitive function. 


CEO and co-founder of Aura Analytics, Daniel Jones, explains how their product works: patients complete a simple, three to five minute set of tasks on a mobile device app that asks specific questions targeting task-specific areas of the brain. The tasks solicit a speech sample from the patient, which is immediately sent to the cloud and subjected to a series of machine learning algorithms that generate and deliver to clinicians in real time objective, finite results.


Built on 25 years worth of data from the National Science Foundation and National Institutes of Health, the Aura Analytics technology has shown a level of accuracy in the 90th percentile of all currently used methods of measuring brain health. Patient feedback has already been overwhelmingly positive, and Aura Analytics is now partnering with major pharmaceutical companies and health systems to carry out large-scale clinical trials and gain more widespread acceptance.


Daniel Jones expects their first major breakthrough with the FDA to happen in about 18 months, and in the meantime, his efforts are focused on gaining external validation and eventual clinician and consumer adoption. Tune in for the full discussion, and visit auralanalytics.com to learn more.  

Amir Inditzky-Dayzz-Developing Comprehensive, Personalized Sleep Training Programs

Sep 18, 2018 25:19

Description:

Most sleep solutions on the market today overlook a critical contributing factor to our quality of sleep: what we do during the day, which includes what we eat, what we do in our free time, and what we do while at work. “The most surprising factor...is how many people actually suffer from sleep disorders….not a lot of people are talking about it but as soon as you give them a stage to talk about it, they are seeking solutions because there are not very good solutions on the market today to treat real sleep disorders,” says Amir Inditzky, CEO of Dayzz. 


Dayzz is taking a holistic approach to the problem of sleep by assessing an individual’s lifestyle and sleeping patterns, collecting data about that individual in a variety of areas during all times of the day, and then creating a highly detailed assessment and training program that not only combines several different sleep solutions in a way that’s tailored to the individual, but also allows for adjustments along the way in order to provide the most well-suited plan.


Interested in finding your solution? The first version of the Dayzz app with be available on your mobile device early this November; simply download the app and get started by answering a few questions about your lifestyle and the problem you’re trying to solve, whether you suspect it’s insomnia, restless leg syndrome, or circadian sleep disorder. So far, Dayzz app users are seeing better results on average than those who’ve sought help from a sleep doctor or clinic--which are hard to come by in the first place. Tune in to learn more and hear the most recent feedback from Dayzz focus groups.

Dr. James Blum-CLEW Medical-Monitoring Critically Ill Patients Using Artificial Intelligence

Sep 18, 2018 22:55

Description:

Despite the use of technologically advanced patient monitoring systems in hospitals, subtle changes in the vital signs of critically ill patients are often inadequately interpreted by medical professionals or else undetected altogether. When a single patient in the ICU can generate gigabytes of data per day, it’s no wonder this is a problem, but that doesn’t mean it’s one that can’t be fixed. 


Dr. James Blum is Chairman of the Advisory Board at CLEW, a company that’s implementing artificial intelligence-based monitoring systems capable of identifying subtle changes in a patient’s vital signs in order to predict the need for specific types of medical intervention hours in advance of an actual medical event. CLEW provides details about what specific problem a patient is likely to experience within a certain period of time, and which means of intervention are likely to be needed. In contrast, technologies developed along similar lines by other companies merely predict that something may go wrong.


CLEW is close to bringing the first iteration of its product to market in ICUs, which focuses on identifying the need to increase doses of blood pressure medications in order to prevent respiratory failure. Since its inception, the team at CLEW has discovered a need for this technology outside of the ICU, on a hospital-wide basis with two primary goals in mind: improving clinical outcomes for patients, and increasing hospital-wide efficiency. 


To learn more, visit <a href="http://clewmed.com">clewmed.com</a>. 

Jon Carder - CEO And Co-Founder - Empyr - O